CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = M196L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3196M196LM1014LnonsynAtgCtg3183000.9433963305-3307
ORF1ab/nsp3196M196LM1014LnonsynAtgTtg318130.04088053305-3307
ORF1ab/nsp3196M196LM1014LnonsynAtGCtA31850.01572333305-3307

Details of the mutation M196L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3196M196LAtgCtg300318All0.000057
ORF1ab/nsp3196M196LAtgTtg13318All0.000002
ORF1ab/nsp3196M196LAtGCtA5318All0.000001
ORF1ab/nsp3196M196LAtgCtg126126AY.40.000196
ORF1ab/nsp3196M196LAtgCtg123123B.1.1770.00162
ORF1ab/nsp3196M196LAtGCtA512B.10.000046
ORF1ab/nsp3196M196LAtgCtg512B.10.000046
ORF1ab/nsp3196M196LAtgTtg212B.10.000018
ORF1ab/nsp3196M196LAtgTtg89P.1.140.000382
ORF1ab/nsp3196M196LAtgCtg19P.1.140.000048
ORF1ab/nsp3196M196LAtgCtg66AY.440.000037
ORF1ab/nsp3196M196LAtgCtg66B.1.4700.008427
ORF1ab/nsp3196M196LAtgCtg44AY.1200.000149
ORF1ab/nsp3196M196LAtgCtg44B.1.1.70.000004
ORF1ab/nsp3196M196LAtgCtg33AY.200.000117
ORF1ab/nsp3196M196LAtgCtg33AY.610.000314
ORF1ab/nsp3196M196LAtgCtg22AY.1030.000012
ORF1ab/nsp3196M196LAtgCtg22B.1.20.000018
ORF1ab/nsp3196M196LAtgCtg22B.1.3510.000059
ORF1ab/nsp3196M196LAtgCtg11AY.1210.000135
ORF1ab/nsp3196M196LAtgCtg11AY.250.000006
ORF1ab/nsp3196M196LAtgCtg11AY.260.000028
ORF1ab/nsp3196M196LAtgCtg11AY.30.00001
ORF1ab/nsp3196M196LAtgCtg11AY.320.000532
ORF1ab/nsp3196M196LAtgCtg11AY.390.000025
ORF1ab/nsp3196M196LAtgCtg11AY.4.50.000107
ORF1ab/nsp3196M196LAtgTtg11B.1.1.4090.002833
ORF1ab/nsp3196M196LAtgCtg11B.1.1600.000031
ORF1ab/nsp3196M196LAtgCtg11B.1.177.150.000631
ORF1ab/nsp3196M196LAtgCtg11B.1.177.370.027027
ORF1ab/nsp3196M196LAtgCtg11B.1.2220.001692
ORF1ab/nsp3196M196LAtgCtg11B.1.36.210.00216
ORF1ab/nsp3196M196LAtgTtg11B.1.4530.003236
ORF1ab/nsp3196M196LAtgCtg11B.1.617.20.000004
ORF1ab/nsp3196M196LAtgTtg11B.290.003509

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.