CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = M196I

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3196M196IM1014InonsynatGatT169611170.6586083305-3307
ORF1ab/nsp3196M196IM1014InonsynatGatA16965430.3201653305-3307
ORF1ab/nsp3196M196IM1014InonsynatGatC1696360.02122643305-3307

Details of the mutation M196I within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3196M196IatGatT11171696All0.000214
ORF1ab/nsp3196M196IatGatA5431696All0.000104
ORF1ab/nsp3196M196IatGatC361696All0.000007
ORF1ab/nsp3196M196IatGatT330330C.370.038301
ORF1ab/nsp3196M196IatGatA101130AY.250.000607
ORF1ab/nsp3196M196IatGatT29130AY.250.000174
ORF1ab/nsp3196M196IatGatA66118B.1.1.70.000059
ORF1ab/nsp3196M196IatGatT41118B.1.1.70.000037
ORF1ab/nsp3196M196IatGatC11118B.1.1.70.00001
ORF1ab/nsp3196M196IatGatA93105AY.290.001467
ORF1ab/nsp3196M196IatGatT12105AY.290.000189
ORF1ab/nsp3196M196IatGatT101101AY.440.000615
ORF1ab/nsp3196M196IatGatT7174AY.30.000706
ORF1ab/nsp3196M196IatGatA374AY.30.00003
ORF1ab/nsp3196M196IatGatT5959B.1.5631
ORF1ab/nsp3196M196IatGatA5555Y.10.705128
ORF1ab/nsp3196M196IatGatT5454B.1.1600.001684
ORF1ab/nsp3196M196IatGatT5252B.1.5170.022203
ORF1ab/nsp3196M196IatGatT2850AY.40.000044
ORF1ab/nsp3196M196IatGatA2150AY.40.000033
ORF1ab/nsp3196M196IatGatC150AY.40.000002
ORF1ab/nsp3196M196IatGatA3541B.1.4290.000824
ORF1ab/nsp3196M196IatGatT641B.1.4290.000141
ORF1ab/nsp3196M196IatGatT3440AY.1030.000211
ORF1ab/nsp3196M196IatGatA540AY.1030.000031
ORF1ab/nsp3196M196IatGatC140AY.1030.000006
ORF1ab/nsp3196M196IatGatT2038B.1.10.000363
ORF1ab/nsp3196M196IatGatA1838B.1.10.000327
ORF1ab/nsp3196M196IatGatA2138B.1.617.20.000079
ORF1ab/nsp3196M196IatGatT1638B.1.617.20.00006
ORF1ab/nsp3196M196IatGatC138B.1.617.20.000004
ORF1ab/nsp3196M196IatGatT3636B.1.6090.017258
ORF1ab/nsp3196M196IatGatT1829B.1.20.000158
ORF1ab/nsp3196M196IatGatA829B.1.20.00007
ORF1ab/nsp3196M196IatGatC329B.1.20.000026
ORF1ab/nsp3196M196IatGatA2929B.1.5950.007568
ORF1ab/nsp3196M196IatGatT1325B.10.000119
ORF1ab/nsp3196M196IatGatA1225B.10.00011
ORF1ab/nsp3196M196IatGatT2121B.1.1700.090517
ORF1ab/nsp3196M196IatGatT2020AY.1180.001253
ORF1ab/nsp3196M196IatGatT1120AY.430.000049
ORF1ab/nsp3196M196IatGatA920AY.430.00004
ORF1ab/nsp3196M196IatGatT1919B.1.36.290.009829
ORF1ab/nsp3196M196IatGatT1518AY.390.000371
ORF1ab/nsp3196M196IatGatA318AY.390.000074
ORF1ab/nsp3196M196IatGatT1313B.1.3620.020031
ORF1ab/nsp3196M196IatGatT89P.10.000126
ORF1ab/nsp3196M196IatGatA19P.10.000016
ORF1ab/nsp3196M196IatGatT78AY.4.20.000152
ORF1ab/nsp3196M196IatGatA18AY.4.20.000022
ORF1ab/nsp3196M196IatGatC88B.1.438.10.000858
ORF1ab/nsp3196M196IatGatA55AY.1020.000133
ORF1ab/nsp3196M196IatGatA45AY.230.000279
ORF1ab/nsp3196M196IatGatT15AY.230.00007
ORF1ab/nsp3196M196IatGatA45AY.39.10.000158
ORF1ab/nsp3196M196IatGatT15AY.39.10.00004
ORF1ab/nsp3196M196IatGatA45B.1.360.000584
ORF1ab/nsp3196M196IatGatT15B.1.360.000146
ORF1ab/nsp3196M196IatGatT34AY.1190.000106
ORF1ab/nsp3196M196IatGatA14AY.1190.000035
ORF1ab/nsp3196M196IatGatA34AY.29.10.000662
ORF1ab/nsp3196M196IatGatT14AY.29.10.000221
ORF1ab/nsp3196M196IatGatA24AY.90.000135
ORF1ab/nsp3196M196IatGatC14AY.90.000068
ORF1ab/nsp3196M196IatGatT14AY.90.000068
ORF1ab/nsp3196M196IatGatA44AY.9.20.000147
ORF1ab/nsp3196M196IatGatA34B.1.1770.00004
ORF1ab/nsp3196M196IatGatC14B.1.1770.000013
ORF1ab/nsp3196M196IatGatT44B.1.4270.000202
ORF1ab/nsp3196M196IatGatT44C.37.10.010471
ORF1ab/nsp3196M196IatGatT230.111111
ORF1ab/nsp3196M196IatGatC130.055556
ORF1ab/nsp3196M196IatGatT23AY.1210.000271
ORF1ab/nsp3196M196IatGatA13AY.1210.000135
ORF1ab/nsp3196M196IatGatT33AY.200.000117
ORF1ab/nsp3196M196IatGatT33AY.4.50.000322
ORF1ab/nsp3196M196IatGatT33AY.610.000314
ORF1ab/nsp3196M196IatGatT33AY.98.10.000145
ORF1ab/nsp3196M196IatGatA33B.1.1.250.001706
ORF1ab/nsp3196M196IatGatC23B.1.1.3060.000877
ORF1ab/nsp3196M196IatGatT13B.1.1.3060.000438
ORF1ab/nsp3196M196IatGatT23B.1.5960.000174
ORF1ab/nsp3196M196IatGatA13B.1.5960.000087
ORF1ab/nsp3196M196IatGatT33B.1.6370.000219
ORF1ab/nsp3196M196IatGatA22AD.20.000438
ORF1ab/nsp3196M196IatGatT22AY.260.000057
ORF1ab/nsp3196M196IatGatA22AY.4.10.001475
ORF1ab/nsp3196M196IatGatA22AY.420.00008
ORF1ab/nsp3196M196IatGatA12AY.50.000021
ORF1ab/nsp3196M196IatGatT12AY.50.000021
ORF1ab/nsp3196M196IatGatT22AY.850.000854
ORF1ab/nsp3196M196IatGatC12B0.000128
ORF1ab/nsp3196M196IatGatT12B0.000128
ORF1ab/nsp3196M196IatGatA12B.1.1.4090.002833
ORF1ab/nsp3196M196IatGatT12B.1.1.4090.002833
ORF1ab/nsp3196M196IatGatC22B.1.1.500.001358
ORF1ab/nsp3196M196IatGatT22B.1.1.5280.009615
ORF1ab/nsp3196M196IatGatT12B.1.2430.00007
ORF1ab/nsp3196M196IatGatA12B.1.2430.00007
ORF1ab/nsp3196M196IatGatT22B.1.3510.000059
ORF1ab/nsp3196M196IatGatA22B.1.36.220.002415
ORF1ab/nsp3196M196IatGatT22B.1.5260.000047
ORF1ab/nsp3196M196IatGatT12C.160.00106
ORF1ab/nsp3196M196IatGatC12C.160.00106
ORF1ab/nsp3196M196IatGatA22P.1.20.002312
ORF1ab/nsp3196M196IatGatT11A0.000387
ORF1ab/nsp3196M196IatGatA11A.270.001656
ORF1ab/nsp3196M196IatGatT11AY.1000.000046
ORF1ab/nsp3196M196IatGatT11AY.1110.000183
ORF1ab/nsp3196M196IatGatA11AY.1170.000085
ORF1ab/nsp3196M196IatGatA11AY.330.000067
ORF1ab/nsp3196M196IatGatT11AY.4.30.000842
ORF1ab/nsp3196M196IatGatT11AY.450.000122
ORF1ab/nsp3196M196IatGatA11AY.46.40.000165
ORF1ab/nsp3196M196IatGatT11AY.470.000031
ORF1ab/nsp3196M196IatGatT11AY.5.40.000277
ORF1ab/nsp3196M196IatGatT11AY.520.000814
ORF1ab/nsp3196M196IatGatA11AY.60.000041
ORF1ab/nsp3196M196IatGatT11AY.7.20.000559
ORF1ab/nsp3196M196IatGatT11AY.750.000056
ORF1ab/nsp3196M196IatGatT11AY.830.001724
ORF1ab/nsp3196M196IatGatC11AY.840.000437
ORF1ab/nsp3196M196IatGatT11AY.870.000833
ORF1ab/nsp3196M196IatGatA11AY.910.00073
ORF1ab/nsp3196M196IatGatT11AY.920.000287
ORF1ab/nsp3196M196IatGatT11AY.950.000761
ORF1ab/nsp3196M196IatGatT11B.1.1.1340.011364
ORF1ab/nsp3196M196IatGatT11B.1.1.1740.003378
ORF1ab/nsp3196M196IatGatT11B.1.1.1890.001513
ORF1ab/nsp3196M196IatGatT11B.1.1.2160.00089
ORF1ab/nsp3196M196IatGatT11B.1.1.280.000311
ORF1ab/nsp3196M196IatGatA11B.1.1.2840.000107
ORF1ab/nsp3196M196IatGatT11B.1.1.2910.000742
ORF1ab/nsp3196M196IatGatT11B.1.1.3030.002762
ORF1ab/nsp3196M196IatGatT11B.1.1.3340.016393
ORF1ab/nsp3196M196IatGatT11B.1.1.5190.00004
ORF1ab/nsp3196M196IatGatA11B.1.1.5260.003546
ORF1ab/nsp3196M196IatGatC11B.1.177.120.000152
ORF1ab/nsp3196M196IatGatT11B.1.1920.009259
ORF1ab/nsp3196M196IatGatT11B.1.2210.000071
ORF1ab/nsp3196M196IatGatA11B.1.2390.001221
ORF1ab/nsp3196M196IatGatA11B.1.2580.000067
ORF1ab/nsp3196M196IatGatA11B.1.36.100.004785
ORF1ab/nsp3196M196IatGatT11B.1.4160.001269
ORF1ab/nsp3196M196IatGatA11B.1.4330.003195
ORF1ab/nsp3196M196IatGatT11B.1.4360.001029
ORF1ab/nsp3196M196IatGatA11B.1.4990.00105
ORF1ab/nsp3196M196IatGatT11B.1.5250.000113
ORF1ab/nsp3196M196IatGatA11B.100.008264
ORF1ab/nsp3196M196IatGatT11D.20.000075
ORF1ab/nsp3196M196IatGatT11P.40.003802

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.