CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L862L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3862L862LL1680LsynttGttA283626320.9280685303-5305
ORF1ab/nsp3862L862LL1680LsynTtgCtg28362040.07193235303-5305

Details of the mutation L862L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3862L862LttGttA26322836All0.000503
ORF1ab/nsp3862L862LTtgCtg2042836All0.000039
ORF1ab/nsp3862L862LttGttA935944AY.250.005624
ORF1ab/nsp3862L862LTtgCtg9944AY.250.000054
ORF1ab/nsp3862L862LttGttA271271B.1.1.440.653012
ORF1ab/nsp3862L862LttGttA216249B.1.1.70.000193
ORF1ab/nsp3862L862LTtgCtg33249B.1.1.70.00003
ORF1ab/nsp3862L862LttGttA187192B.1.617.20.000704
ORF1ab/nsp3862L862LTtgCtg5192B.1.617.20.000019
ORF1ab/nsp3862L862LttGttA110137AY.430.000487
ORF1ab/nsp3862L862LTtgCtg27137AY.430.00012
ORF1ab/nsp3862L862LttGttA106110AY.440.000645
ORF1ab/nsp3862L862LTtgCtg4110AY.440.000024
ORF1ab/nsp3862L862LTtgCtg8086AY.470.002488
ORF1ab/nsp3862L862LttGttA686AY.470.000187
ORF1ab/nsp3862L862LttGttA5256B.10.000476
ORF1ab/nsp3862L862LTtgCtg456B.10.000037
ORF1ab/nsp3862L862LttGttA5056B.1.20.00044
ORF1ab/nsp3862L862LTtgCtg656B.1.20.000053
ORF1ab/nsp3862L862LttGttA4449AY.40.000068
ORF1ab/nsp3862L862LTtgCtg549AY.40.000008
ORF1ab/nsp3862L862LttGttA3838B.1.6370.002777
ORF1ab/nsp3862L862LttGttA3536AY.1030.000217
ORF1ab/nsp3862L862LTtgCtg136AY.1030.000006
ORF1ab/nsp3862L862LttGttA2626AY.9.20.000955
ORF1ab/nsp3862L862LttGttA2424B.1.5260.000564
ORF1ab/nsp3862L862LttGttA2323AY.1020.00061
ORF1ab/nsp3862L862LttGttA2323B.1.1.4340.008017
ORF1ab/nsp3862L862LttGttA2323Q.10.002906
ORF1ab/nsp3862L862LttGttA2121B.1.2210.001492
ORF1ab/nsp3862L862LttGttA1718B.1.10.000308
ORF1ab/nsp3862L862LTtgCtg118B.1.10.000018
ORF1ab/nsp3862L862LttGttA1616AY.260.000453
ORF1ab/nsp3862L862LttGttA1414AY.330.000935
ORF1ab/nsp3862L862LTtgCtg1013B.1.4290.000235
ORF1ab/nsp3862L862LttGttA313B.1.4290.000071
ORF1ab/nsp3862L862LttGttA1212B.1.2400.002587
ORF1ab/nsp3862L862LttGttA99AY.30.00009
ORF1ab/nsp3862L862LttGttA89AY.390.000198
ORF1ab/nsp3862L862LTtgCtg19AY.390.000025
ORF1ab/nsp3862L862LttGttA99AY.4.20.000195
ORF1ab/nsp3862L862LttGttA99AY.5.40.00249
ORF1ab/nsp3862L862LttGttA99AY.90.000608
ORF1ab/nsp3862L862LttGttA99AY.98.10.000436
ORF1ab/nsp3862L862LttGttA99B.1.1.2540.101124
ORF1ab/nsp3862L862LttGttA99B.1.5750.002731
ORF1ab/nsp3862L862LttGttA99P.10.000142
ORF1ab/nsp3862L862LttGttA88AY.120.10.002568
ORF1ab/nsp3862L862LttGttA88B.1.4090.00625
ORF1ab/nsp3862L862LttGttA77AY.160.002658
ORF1ab/nsp3862L862LttGttA77AY.880.006189
ORF1ab/nsp3862L862LttGttA77B.1.1.3170.002882
ORF1ab/nsp3862L862LttGttA77B.1.1600.000218
ORF1ab/nsp3862L862LttGttA77B.1.6210.00062
ORF1ab/nsp3862L862LttGttA66AY.1200.000223
ORF1ab/nsp3862L862LttGttA66AY.420.000241
ORF1ab/nsp3862L862LttGttA56B.1.1.5190.000199
ORF1ab/nsp3862L862LTtgCtg16B.1.1.5190.00004
ORF1ab/nsp3862L862LttGttA56B.1.1770.000066
ORF1ab/nsp3862L862LTtgCtg16B.1.1770.000013
ORF1ab/nsp3862L862LttGttA66B.1.2430.000418
ORF1ab/nsp3862L862LttGttA66B.1.5170.002562
ORF1ab/nsp3862L862LttGttA66B.1.5670.02
ORF1ab/nsp3862L862LttGttA66B.1.5820.002944
ORF1ab/nsp3862L862LttGttA55AY.1130.000712
ORF1ab/nsp3862L862LttGttA55AY.1180.000313
ORF1ab/nsp3862L862LttGttA55AY.200.000194
ORF1ab/nsp3862L862LttGttA55AY.460.00052
ORF1ab/nsp3862L862LttGttA55AY.930.001365
ORF1ab/nsp3862L862LttGttA440.222222
ORF1ab/nsp3862L862LttGttA44A.270.006623
ORF1ab/nsp3862L862LttGttA44AY.46.40.000658
ORF1ab/nsp3862L862LttGttA44AY.46.60.000289
ORF1ab/nsp3862L862LTtgCtg34AY.50.000062
ORF1ab/nsp3862L862LttGttA14AY.50.000021
ORF1ab/nsp3862L862LttGttA44B.1.1.4200.004024
ORF1ab/nsp3862L862LttGttA44B.1.1.4860.006309
ORF1ab/nsp3862L862LttGttA44B.1.1810.078431
ORF1ab/nsp3862L862LttGttA33AY.290.000047
ORF1ab/nsp3862L862LttGttA33AY.4.40.001227
ORF1ab/nsp3862L862LttGttA33AY.540.000286
ORF1ab/nsp3862L862LttGttA23AY.610.00021
ORF1ab/nsp3862L862LTtgCtg13AY.610.000105
ORF1ab/nsp3862L862LttGttA33AY.700.000626
ORF1ab/nsp3862L862LttGttA33AY.730.001996
ORF1ab/nsp3862L862LTtgCtg23AY.750.000112
ORF1ab/nsp3862L862LttGttA13AY.750.000056
ORF1ab/nsp3862L862LttGttA23AY.75.10.000361
ORF1ab/nsp3862L862LTtgCtg13AY.75.10.00018
ORF1ab/nsp3862L862LttGttA33B.1.3510.000089
ORF1ab/nsp3862L862LttGttA33B.1.36.290.001552
ORF1ab/nsp3862L862LttGttA33C.370.000348
ORF1ab/nsp3862L862LttGttA33P.1.160.001122
ORF1ab/nsp3862L862LTtgCtg12AY.1160.000287
ORF1ab/nsp3862L862LttGttA12AY.1160.000287
ORF1ab/nsp3862L862LttGttA22AY.1190.000071
ORF1ab/nsp3862L862LttGttA22AY.140.000176
ORF1ab/nsp3862L862LttGttA22AY.240.000862
ORF1ab/nsp3862L862LttGttA22AY.450.000243
ORF1ab/nsp3862L862LttGttA22AY.490.00639
ORF1ab/nsp3862L862LttGttA22AY.60.000082
ORF1ab/nsp3862L862LttGttA22AY.660.002139
ORF1ab/nsp3862L862LttGttA22AY.670.000929
ORF1ab/nsp3862L862LttGttA22AY.860.00166
ORF1ab/nsp3862L862LttGttA22AY.9.10.000167
ORF1ab/nsp3862L862LttGttA22B.1.1.1610.007067
ORF1ab/nsp3862L862LttGttA22B.1.1.2220.000408
ORF1ab/nsp3862L862LttGttA22B.1.1.3180.000604
ORF1ab/nsp3862L862LttGttA22B.1.1.3620.011236
ORF1ab/nsp3862L862LTtgCtg22B.1.177.210.000153
ORF1ab/nsp3862L862LttGttA22B.1.177.770.001452
ORF1ab/nsp3862L862LttGttA22B.1.2340.000264
ORF1ab/nsp3862L862LttGttA22B.1.3490.00143
ORF1ab/nsp3862L862LttGttA22B.1.4430.009346
ORF1ab/nsp3862L862LttGttA22B.1.4780.023529
ORF1ab/nsp3862L862LttGttA22B.1.5250.000226
ORF1ab/nsp3862L862LttGttA22B.1.5430.02
ORF1ab/nsp3862L862LttGttA22B.1.5600.009259
ORF1ab/nsp3862L862LttGttA22B.1.5880.00182
ORF1ab/nsp3862L862LttGttA22B.1.5950.000522
ORF1ab/nsp3862L862LTtgCtg22B.1.5960.000174
ORF1ab/nsp3862L862LttGttA22P.1.170.000324
ORF1ab/nsp3862L862LttGttA22Q.30.00029
ORF1ab/nsp3862L862LttGttA22Q.80.00033
ORF1ab/nsp3862L862LttGttA11AY.10.000396
ORF1ab/nsp3862L862LttGttA11AY.1000.000046
ORF1ab/nsp3862L862LttGttA11AY.1060.000335
ORF1ab/nsp3862L862LttGttA11AY.1070.000466
ORF1ab/nsp3862L862LttGttA11AY.1090.00074
ORF1ab/nsp3862L862LttGttA11AY.1100.000113
ORF1ab/nsp3862L862LttGttA11AY.116.10.000311
ORF1ab/nsp3862L862LttGttA11AY.1210.000135
ORF1ab/nsp3862L862LttGttA11AY.20.000356
ORF1ab/nsp3862L862LttGttA11AY.300.000396
ORF1ab/nsp3862L862LttGttA11AY.340.000097
ORF1ab/nsp3862L862LttGttA11AY.34.10.00051
ORF1ab/nsp3862L862LttGttA11AY.350.000233
ORF1ab/nsp3862L862LttGttA11AY.370.000316
ORF1ab/nsp3862L862LttGttA11AY.380.000499
ORF1ab/nsp3862L862LttGttA11AY.4.30.000842
ORF1ab/nsp3862L862LTtgCtg11AY.410.000294
ORF1ab/nsp3862L862LttGttA11AY.5.20.002463
ORF1ab/nsp3862L862LttGttA11AY.5.30.000337
ORF1ab/nsp3862L862LttGttA11AY.520.000814
ORF1ab/nsp3862L862LttGttA11AY.580.000907
ORF1ab/nsp3862L862LttGttA11AY.620.000436
ORF1ab/nsp3862L862LttGttA11AY.640.000595
ORF1ab/nsp3862L862LttGttA11AY.650.000533
ORF1ab/nsp3862L862LttGttA11AY.70.000196
ORF1ab/nsp3862L862LttGttA11AY.710.000475
ORF1ab/nsp3862L862LttGttA11AY.720.001361
ORF1ab/nsp3862L862LttGttA11AY.740.000116
ORF1ab/nsp3862L862LttGttA11AY.920.000287
ORF1ab/nsp3862L862LttGttA11AY.980.000079
ORF1ab/nsp3862L862LttGttA11B0.000128
ORF1ab/nsp3862L862LttGttA11B.1.1.1920.002309
ORF1ab/nsp3862L862LttGttA11B.1.1.2070.001182
ORF1ab/nsp3862L862LttGttA11B.1.1.2160.00089
ORF1ab/nsp3862L862LttGttA11B.1.1.2310.003096
ORF1ab/nsp3862L862LttGttA11B.1.1.3160.000925
ORF1ab/nsp3862L862LttGttA11B.1.1.4090.002833
ORF1ab/nsp3862L862LttGttA11B.1.1.4110.014706
ORF1ab/nsp3862L862LttGttA11B.1.1.4320.001266
ORF1ab/nsp3862L862LttGttA11B.1.1.5180.006329
ORF1ab/nsp3862L862LttGttA11B.1.1.740.00431
ORF1ab/nsp3862L862LttGttA11B.1.110.30.000718
ORF1ab/nsp3862L862LttGttA11B.1.177.620.001192
ORF1ab/nsp3862L862LttGttA11B.1.2060.000816
ORF1ab/nsp3862L862LttGttA11B.1.2540.025
ORF1ab/nsp3862L862LttGttA11B.1.258.170.000104
ORF1ab/nsp3862L862LttGttA11B.1.2980.002114
ORF1ab/nsp3862L862LttGttA11B.1.3050.002151
ORF1ab/nsp3862L862LttGttA11B.1.3060.005714
ORF1ab/nsp3862L862LttGttA11B.1.3130.006579
ORF1ab/nsp3862L862LttGttA11B.1.351.30.000876
ORF1ab/nsp3862L862LttGttA11B.1.3550.011111
ORF1ab/nsp3862L862LttGttA11B.1.3690.000285
ORF1ab/nsp3862L862LttGttA11B.1.3750.00082
ORF1ab/nsp3862L862LttGttA11B.1.3970.004854
ORF1ab/nsp3862L862LttGttA11B.1.4050.012346
ORF1ab/nsp3862L862LTtgCtg11B.1.4160.001269
ORF1ab/nsp3862L862LttGttA11B.1.4270.00005
ORF1ab/nsp3862L862LttGttA11B.1.438.10.000107
ORF1ab/nsp3862L862LTtgCtg11B.1.5580.004566
ORF1ab/nsp3862L862LttGttA11B.1.595.10.005848
ORF1ab/nsp3862L862LttGttA11B.1.621.10.000506
ORF1ab/nsp3862L862LttGttA11B.1.6360.006711
ORF1ab/nsp3862L862LTtgCtg11P.1.150.000232
ORF1ab/nsp3862L862LttGttA11P.60.003145
ORF1ab/nsp3862L862LttGttA11P.70.004367

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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