CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L689L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3689L689LL1507LsynctTctC3072070.6742674784-4786
ORF1ab/nsp3689L689LL1507LsynctTctA307560.182414784-4786
ORF1ab/nsp3689L689LL1507LsynctTctG307430.1400654784-4786
ORF1ab/nsp3689L689LL1507LsynCtTTtA30710.003257334784-4786

Details of the mutation L689L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3689L689LctTctC207307All0.00004
ORF1ab/nsp3689L689LctTctA56307All0.000011
ORF1ab/nsp3689L689LctTctG43307All0.000008
ORF1ab/nsp3689L689LCtTTtA1307All0
ORF1ab/nsp3689L689LctTctC100108B.1.1.70.00009
ORF1ab/nsp3689L689LctTctA7108B.1.1.70.000006
ORF1ab/nsp3689L689LctTctG1108B.1.1.70.000001
ORF1ab/nsp3689L689LctTctG3438B.1.1770.000448
ORF1ab/nsp3689L689LctTctA438B.1.1770.000053
ORF1ab/nsp3689L689LctTctC2326AY.40.000036
ORF1ab/nsp3689L689LctTctA326AY.40.000005
ORF1ab/nsp3689L689LctTctA1515B.1.6270.030303
ORF1ab/nsp3689L689LctTctC1212AY.250.000072
ORF1ab/nsp3689L689LctTctC58B.1.1600.000156
ORF1ab/nsp3689L689LctTctG28B.1.1600.000062
ORF1ab/nsp3689L689LctTctA18B.1.1600.000031
ORF1ab/nsp3689L689LctTctC77AY.1170.000592
ORF1ab/nsp3689L689LctTctC77B.1.360.001021
ORF1ab/nsp3689L689LctTctA36B.10.000027
ORF1ab/nsp3689L689LctTctC26B.10.000018
ORF1ab/nsp3689L689LCtTTtA16B.10.000009
ORF1ab/nsp3689L689LctTctC66B.1.1.2770.004552
ORF1ab/nsp3689L689LctTctC46B.1.617.20.000015
ORF1ab/nsp3689L689LctTctA16B.1.617.20.000004
ORF1ab/nsp3689L689LctTctG16B.1.617.20.000004
ORF1ab/nsp3689L689LctTctC55AY.240.002155
ORF1ab/nsp3689L689LctTctC55AY.470.000156
ORF1ab/nsp3689L689LctTctC23AY.390.000049
ORF1ab/nsp3689L689LctTctA13AY.390.000025
ORF1ab/nsp3689L689LctTctC33B.1.1.1890.004539
ORF1ab/nsp3689L689LctTctC33B.1.1.5190.000119
ORF1ab/nsp3689L689LctTctA33B.1.177.40.000633
ORF1ab/nsp3689L689LctTctC22AY.1030.000012
ORF1ab/nsp3689L689LctTctA12AY.1200.000037
ORF1ab/nsp3689L689LctTctC12AY.1200.000037
ORF1ab/nsp3689L689LctTctA12AY.260.000028
ORF1ab/nsp3689L689LctTctG12AY.260.000028
ORF1ab/nsp3689L689LctTctC22AY.30.00002
ORF1ab/nsp3689L689LctTctG12AY.440.000006
ORF1ab/nsp3689L689LctTctA12AY.440.000006
ORF1ab/nsp3689L689LctTctA12B.1.20.000009
ORF1ab/nsp3689L689LctTctC12B.1.20.000009
ORF1ab/nsp3689L689LctTctC11A.2.20.001689
ORF1ab/nsp3689L689LctTctC11AY.16.10.00047
ORF1ab/nsp3689L689LctTctG11AY.270.000065
ORF1ab/nsp3689L689LctTctC11AY.4.20.000022
ORF1ab/nsp3689L689LctTctC11AY.4.2.10.000149
ORF1ab/nsp3689L689LctTctC11AY.430.000004
ORF1ab/nsp3689L689LctTctA11AY.46.40.000165
ORF1ab/nsp3689L689LctTctA11AY.46.50.000198
ORF1ab/nsp3689L689LctTctA11AY.520.000814
ORF1ab/nsp3689L689LctTctA11AY.60.000041
ORF1ab/nsp3689L689LctTctC11AY.680.000274
ORF1ab/nsp3689L689LctTctC11AY.750.000056
ORF1ab/nsp3689L689LctTctA11AZ.10.000867
ORF1ab/nsp3689L689LctTctA11B0.000128
ORF1ab/nsp3689L689LctTctA11B.1.10.000018
ORF1ab/nsp3689L689LctTctC11B.1.1.4190.007407
ORF1ab/nsp3689L689LctTctC11B.1.160.160.000929
ORF1ab/nsp3689L689LctTctC11B.1.177.170.000821
ORF1ab/nsp3689L689LctTctG11B.1.177.310.011494
ORF1ab/nsp3689L689LctTctG11B.1.2230.002778
ORF1ab/nsp3689L689LctTctC11B.1.2390.001221
ORF1ab/nsp3689L689LctTctA11B.1.36.360.000602
ORF1ab/nsp3689L689LctTctC11B.1.3670.000792
ORF1ab/nsp3689L689LctTctC11B.1.4270.00005
ORF1ab/nsp3689L689LctTctA11B.1.4290.000024
ORF1ab/nsp3689L689LctTctA11B.1.5950.000261
ORF1ab/nsp3689L689LctTctC11B.1.5960.000087
ORF1ab/nsp3689L689LctTctC11B.1.619.10.000641
ORF1ab/nsp3689L689LctTctA11B.4.40.018868
ORF1ab/nsp3689L689LctTctC11B.400.000364
ORF1ab/nsp3689L689LctTctA11C.280.04
ORF1ab/nsp3689L689LctTctC11P.10.000016
ORF1ab/nsp3689L689LctTctA11P.1.170.000162
ORF1ab/nsp3689L689LctTctA11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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