CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L651L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3651L651LL1469LsynctCctT116810550.9032534670-4672
ORF1ab/nsp3651L651LL1469LsynctCctA11681030.08818494670-4672
ORF1ab/nsp3651L651LL1469LsynCtCTtA116840.003424664670-4672
ORF1ab/nsp3651L651LL1469LsynctCctG116830.002568494670-4672
ORF1ab/nsp3651L651LL1469LsynCtCTtG116830.002568494670-4672

Details of the mutation L651L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3651L651LctCctT10551168All0.000202
ORF1ab/nsp3651L651LctCctA1031168All0.00002
ORF1ab/nsp3651L651LCtCTtA41168All0.000001
ORF1ab/nsp3651L651LctCctG31168All0.000001
ORF1ab/nsp3651L651LCtCTtG31168All0.000001
ORF1ab/nsp3651L651LctCctT276278AY.40.00043
ORF1ab/nsp3651L651LctCctA2278AY.40.000003
ORF1ab/nsp3651L651LctCctT160180B.1.1.70.000143
ORF1ab/nsp3651L651LctCctA20180B.1.1.70.000018
ORF1ab/nsp3651L651LctCctT145145B.1.5260.003408
ORF1ab/nsp3651L651LctCctT8686B.1.36.20.924731
ORF1ab/nsp3651L651LctCctT3547B.10.000321
ORF1ab/nsp3651L651LctCctA747B.10.000064
ORF1ab/nsp3651L651LctCctG247B.10.000018
ORF1ab/nsp3651L651LCtCTtG247B.10.000018
ORF1ab/nsp3651L651LCtCTtA147B.10.000009
ORF1ab/nsp3651L651LctCctT2828B.1.20.000247
ORF1ab/nsp3651L651LctCctT2325AY.50.000475
ORF1ab/nsp3651L651LctCctA225AY.50.000041
ORF1ab/nsp3651L651LctCctT2223AY.250.000132
ORF1ab/nsp3651L651LctCctA123AY.250.000006
ORF1ab/nsp3651L651LctCctT2222AY.440.000134
ORF1ab/nsp3651L651LctCctT2121AY.1030.00013
ORF1ab/nsp3651L651LctCctT2121AY.130.003381
ORF1ab/nsp3651L651LctCctT1320B.1.617.20.000049
ORF1ab/nsp3651L651LctCctA620B.1.617.20.000023
ORF1ab/nsp3651L651LCtCTtA120B.1.617.20.000004
ORF1ab/nsp3651L651LctCctT1318B.1.10.000236
ORF1ab/nsp3651L651LctCctA218B.1.10.000036
ORF1ab/nsp3651L651LCtCTtA118B.1.10.000018
ORF1ab/nsp3651L651LctCctG118B.1.10.000018
ORF1ab/nsp3651L651LCtCTtG118B.1.10.000018
ORF1ab/nsp3651L651LctCctA1017AY.30.000099
ORF1ab/nsp3651L651LctCctT717AY.30.00007
ORF1ab/nsp3651L651LctCctA1117B.1.2430.000765
ORF1ab/nsp3651L651LctCctT617B.1.2430.000418
ORF1ab/nsp3651L651LctCctT1616AY.260.000453
ORF1ab/nsp3651L651LctCctT915P.10.000142
ORF1ab/nsp3651L651LctCctA615P.10.000095
ORF1ab/nsp3651L651LctCctT1112AY.430.000049
ORF1ab/nsp3651L651LctCctA112AY.430.000004
ORF1ab/nsp3651L651LctCctT1111AY.390.000272
ORF1ab/nsp3651L651LctCctT99B.1.1770.000119
ORF1ab/nsp3651L651LctCctT77B.1.36.220.008454
ORF1ab/nsp3651L651LctCctA56B.1.5960.000436
ORF1ab/nsp3651L651LctCctT16B.1.5960.000087
ORF1ab/nsp3651L651LctCctT55AY.650.002665
ORF1ab/nsp3651L651LctCctT35B.1.3510.000089
ORF1ab/nsp3651L651LctCctA25B.1.3510.000059
ORF1ab/nsp3651L651LctCctT55B.1.351.50.002998
ORF1ab/nsp3651L651LctCctT55B.1.36.330.037879
ORF1ab/nsp3651L651LctCctT34AY.1020.00008
ORF1ab/nsp3651L651LctCctA14AY.1020.000027
ORF1ab/nsp3651L651LctCctA44AY.1080.00441
ORF1ab/nsp3651L651LctCctT44AY.200.000155
ORF1ab/nsp3651L651LctCctT44AY.420.000161
ORF1ab/nsp3651L651LctCctT44B.1.1.5190.000159
ORF1ab/nsp3651L651LctCctA44B.1.2400.000862
ORF1ab/nsp3651L651LctCctA23AY.230.000139
ORF1ab/nsp3651L651LctCctT13AY.230.00007
ORF1ab/nsp3651L651LctCctT23AY.39.10.000079
ORF1ab/nsp3651L651LctCctA13AY.39.10.00004
ORF1ab/nsp3651L651LctCctA33AY.450.000365
ORF1ab/nsp3651L651LctCctT33AY.9.20.00011
ORF1ab/nsp3651L651LctCctA23AY.980.000158
ORF1ab/nsp3651L651LctCctT13AY.980.000079
ORF1ab/nsp3651L651LctCctT33B.1.1.3060.001315
ORF1ab/nsp3651L651LCtCTtA13B.1.1.4090.002833
ORF1ab/nsp3651L651LctCctA13B.1.1.4090.002833
ORF1ab/nsp3651L651LctCctT13B.1.1.4090.002833
ORF1ab/nsp3651L651LctCctT33B.1.4090.002344
ORF1ab/nsp3651L651LctCctT33C.360.002732
ORF1ab/nsp3651L651LctCctT33Q.10.000379
ORF1ab/nsp3651L651LctCctT22AY.1200.000074
ORF1ab/nsp3651L651LctCctT22AY.290.000032
ORF1ab/nsp3651L651LctCctT22AY.530.000575
ORF1ab/nsp3651L651LctCctA22AY.750.000112
ORF1ab/nsp3651L651LctCctA12B.1.2340.000132
ORF1ab/nsp3651L651LctCctT12B.1.2340.000132
ORF1ab/nsp3651L651LctCctT22B.1.2580.000133
ORF1ab/nsp3651L651LctCctT22B.1.360.000292
ORF1ab/nsp3651L651LctCctA12B.1.4290.000024
ORF1ab/nsp3651L651LctCctT12B.1.4290.000024
ORF1ab/nsp3651L651LctCctT22B.1.617.10.000258
ORF1ab/nsp3651L651LctCctT12B.1.6190.000871
ORF1ab/nsp3651L651LctCctA12B.1.6190.000871
ORF1ab/nsp3651L651LctCctT22B.1.6210.000177
ORF1ab/nsp3651L651LctCctT22B.1.6370.000146
ORF1ab/nsp3651L651LctCctT22B.1.910.004149
ORF1ab/nsp3651L651LctCctT11A.30.002096
ORF1ab/nsp3651L651LctCctT11AY.1000.000046
ORF1ab/nsp3651L651LctCctT11AY.1090.00074
ORF1ab/nsp3651L651LctCctT11AY.1140.000231
ORF1ab/nsp3651L651LctCctT11AY.116.10.000311
ORF1ab/nsp3651L651LctCctT11AY.1170.000085
ORF1ab/nsp3651L651LctCctT11AY.140.000088
ORF1ab/nsp3651L651LctCctT11AY.280.00189
ORF1ab/nsp3651L651LctCctT11AY.360.000148
ORF1ab/nsp3651L651LctCctT11AY.370.000316
ORF1ab/nsp3651L651LctCctA11AY.4.50.000107
ORF1ab/nsp3651L651LctCctT11AY.46.50.000198
ORF1ab/nsp3651L651LctCctT11AY.590.00053
ORF1ab/nsp3651L651LctCctT11AY.610.000105
ORF1ab/nsp3651L651LctCctT11AY.700.000209
ORF1ab/nsp3651L651LctCctT11AY.890.004902
ORF1ab/nsp3651L651LctCctT11B0.000128
ORF1ab/nsp3651L651LctCctT11B.1.1.2140.000055
ORF1ab/nsp3651L651LctCctT11B.1.1.250.000569
ORF1ab/nsp3651L651LctCctT11B.1.1.2790.001121
ORF1ab/nsp3651L651LctCctT11B.1.1.2840.000107
ORF1ab/nsp3651L651LctCctT11B.1.1.3260.001761
ORF1ab/nsp3651L651LctCctT11B.1.1.3620.005618
ORF1ab/nsp3651L651LctCctT11B.1.1.500.000679
ORF1ab/nsp3651L651LctCctT11B.1.1.930.025641
ORF1ab/nsp3651L651LctCctT11B.1.214.20.0006
ORF1ab/nsp3651L651LctCctT11B.1.2320.000537
ORF1ab/nsp3651L651LctCctT11B.1.3460.001311
ORF1ab/nsp3651L651LctCctT11B.1.351.20.000303
ORF1ab/nsp3651L651LctCctT11B.1.36.170.000494
ORF1ab/nsp3651L651LctCctA11B.1.4240.008065
ORF1ab/nsp3651L651LctCctT11B.1.4270.00005
ORF1ab/nsp3651L651LctCctT11B.1.4560.003268
ORF1ab/nsp3651L651LctCctA11B.1.4600.017857
ORF1ab/nsp3651L651LctCctT11B.1.4680.005714
ORF1ab/nsp3651L651LctCctA11B.1.4700.001404
ORF1ab/nsp3651L651LctCctT11B.1.4970.000315
ORF1ab/nsp3651L651LctCctT11B.1.6280.000352
ORF1ab/nsp3651L651LctCctA11B.60.00091
ORF1ab/nsp3651L651LctCctT11C.260.007353
ORF1ab/nsp3651L651LctCctT11D.20.000075
ORF1ab/nsp3651L651LctCctT11P.1.100.000269
ORF1ab/nsp3651L651LctCctT11P.30.001595
ORF1ab/nsp3651L651LctCctT11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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