CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L550L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3550L550LL1368LsynctTctC8045560.6915424367-4369
ORF1ab/nsp3550L550LL1368LsynctTctA8042220.2761194367-4369
ORF1ab/nsp3550L550LL1368LsynctTctG804160.01990054367-4369
ORF1ab/nsp3550L550LL1368LsynCtTTtG80490.0111944367-4369
ORF1ab/nsp3550L550LL1368LsynCtTTtA80410.001243784367-4369

Details of the mutation L550L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3550L550LctTctC556804All0.000106
ORF1ab/nsp3550L550LctTctA222804All0.000042
ORF1ab/nsp3550L550LctTctG16804All0.000003
ORF1ab/nsp3550L550LCtTTtG9804All0.000002
ORF1ab/nsp3550L550LCtTTtA1804All0
ORF1ab/nsp3550L550LctTctC323323B.1.1.2800.996914
ORF1ab/nsp3550L550LctTctA95104AY.1030.00059
ORF1ab/nsp3550L550LctTctC9104AY.1030.000056
ORF1ab/nsp3550L550LctTctA6771AY.430.000297
ORF1ab/nsp3550L550LctTctG271AY.430.000009
ORF1ab/nsp3550L550LctTctC271AY.430.000009
ORF1ab/nsp3550L550LctTctC5660AY.30.000557
ORF1ab/nsp3550L550LctTctA460AY.30.00004
ORF1ab/nsp3550L550LctTctC5656AY.1110.010256
ORF1ab/nsp3550L550LctTctC2224B.10.000202
ORF1ab/nsp3550L550LctTctA124B.10.000009
ORF1ab/nsp3550L550LctTctG124B.10.000009
ORF1ab/nsp3550L550LctTctC916B.1.1.70.000008
ORF1ab/nsp3550L550LctTctA616B.1.1.70.000005
ORF1ab/nsp3550L550LctTctG116B.1.1.70.000001
ORF1ab/nsp3550L550LctTctC914AY.40.000014
ORF1ab/nsp3550L550LctTctA514AY.40.000008
ORF1ab/nsp3550L550LctTctC1313AY.5.40.003597
ORF1ab/nsp3550L550LctTctA77AY.1190.000247
ORF1ab/nsp3550L550LCtTTtG77AY.140.000616
ORF1ab/nsp3550L550LctTctG26AY.250.000012
ORF1ab/nsp3550L550LctTctA26AY.250.000012
ORF1ab/nsp3550L550LctTctC26AY.250.000012
ORF1ab/nsp3550L550LctTctC55AD.20.001095
ORF1ab/nsp3550L550LctTctA55AY.610.000524
ORF1ab/nsp3550L550LctTctC45B.1.20.000035
ORF1ab/nsp3550L550LctTctG15B.1.20.000009
ORF1ab/nsp3550L550LctTctC55B.1.5750.001517
ORF1ab/nsp3550L550LctTctC34AY.330.0002
ORF1ab/nsp3550L550LctTctA14AY.330.000067
ORF1ab/nsp3550L550LctTctA34AY.350.000699
ORF1ab/nsp3550L550LctTctC14AY.350.000233
ORF1ab/nsp3550L550LctTctC44B.1.177.810.000757
ORF1ab/nsp3550L550LctTctA44B.1.3750.003279
ORF1ab/nsp3550L550LctTctA33B.1.1600.000094
ORF1ab/nsp3550L550LctTctC33B.1.360.000438
ORF1ab/nsp3550L550LctTctC33B.1.4700.004213
ORF1ab/nsp3550L550LctTctC33B.1.617.20.000011
ORF1ab/nsp3550L550LctTctA23C.370.000232
ORF1ab/nsp3550L550LctTctC13C.370.000116
ORF1ab/nsp3550L550LctTctC22AY.240.000862
ORF1ab/nsp3550L550LctTctA12AY.270.000065
ORF1ab/nsp3550L550LctTctG12AY.270.000065
ORF1ab/nsp3550L550LctTctC22AY.370.000632
ORF1ab/nsp3550L550LctTctA22AY.440.000012
ORF1ab/nsp3550L550LctTctG12AY.46.60.000072
ORF1ab/nsp3550L550LctTctC12AY.46.60.000072
ORF1ab/nsp3550L550LCtTTtG12AY.540.000095
ORF1ab/nsp3550L550LctTctA12AY.540.000095
ORF1ab/nsp3550L550LctTctA22B.1.1.3260.003521
ORF1ab/nsp3550L550LctTctC22B.1.1.330.000842
ORF1ab/nsp3550L550LctTctC22B.1.1770.000026
ORF1ab/nsp3550L550LCtTTtG12B.1.258.170.000104
ORF1ab/nsp3550L550LctTctC12B.1.258.170.000104
ORF1ab/nsp3550L550LctTctG22B.1.466.20.000782
ORF1ab/nsp3550L550LctTctA22C.360.001821
ORF1ab/nsp3550L550LctTctC22P.10.000032
ORF1ab/nsp3550L550LctTctC11AU.20.002421
ORF1ab/nsp3550L550LctTctC11AY.1020.000027
ORF1ab/nsp3550L550LctTctA11AY.1130.000142
ORF1ab/nsp3550L550LctTctA11AY.160.00038
ORF1ab/nsp3550L550LctTctG11AY.3.10.000085
ORF1ab/nsp3550L550LctTctC11AY.4.50.000107
ORF1ab/nsp3550L550LctTctC11AY.460.000104
ORF1ab/nsp3550L550LctTctC11AY.480.000465
ORF1ab/nsp3550L550LctTctC11AY.660.00107
ORF1ab/nsp3550L550LctTctA11AY.70.000196
ORF1ab/nsp3550L550LctTctA11AY.850.000427
ORF1ab/nsp3550L550LctTctC11AY.920.000287
ORF1ab/nsp3550L550LctTctG11B.1.10.000018
ORF1ab/nsp3550L550LctTctG11B.1.1.1740.003378
ORF1ab/nsp3550L550LctTctA11B.1.1.630.000386
ORF1ab/nsp3550L550LctTctC11B.1.177.60.000977
ORF1ab/nsp3550L550LctTctC11B.1.177.600.000218
ORF1ab/nsp3550L550LctTctC11B.1.177.860.000183
ORF1ab/nsp3550L550LCtTTtA11B.1.2370.004975
ORF1ab/nsp3550L550LctTctA11B.1.4290.000024
ORF1ab/nsp3550L550LctTctC11B.1.5960.000087
ORF1ab/nsp3550L550LctTctG11B.1.5970.00463
ORF1ab/nsp3550L550LctTctA11B.400.000364
ORF1ab/nsp3550L550LctTctA11B.6.60.000889
ORF1ab/nsp3550L550LctTctG11D.20.000075
ORF1ab/nsp3550L550LctTctA11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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