CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L312F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3312L312FL1130FnonsynCttTtt5873587313653-3655

Details of the mutation L312F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3312L312FCttTtt58735873All0.001123
ORF1ab/nsp3312L312FCttTtt867867B.1.1.70.000776
ORF1ab/nsp3312L312FCttTtt853853AY.390.021079
ORF1ab/nsp3312L312FCttTtt472472AY.40.000735
ORF1ab/nsp3312L312FCttTtt359359AY.1030.002229
ORF1ab/nsp3312L312FCttTtt249249B.10.002281
ORF1ab/nsp3312L312FCttTtt183183AY.440.001114
ORF1ab/nsp3312L312FCttTtt172172B.1.438.10.018449
ORF1ab/nsp3312L312FCttTtt169169P.1.170.027337
ORF1ab/nsp3312L312FCttTtt166166AY.420.006678
ORF1ab/nsp3312L312FCttTtt158158AY.460.016445
ORF1ab/nsp3312L312FCttTtt141141B.1.617.20.000531
ORF1ab/nsp3312L312FCttTtt125125AY.430.000554
ORF1ab/nsp3312L312FCttTtt122122B.1.20.001074
ORF1ab/nsp3312L312FCttTtt109109B.1.10.001977
ORF1ab/nsp3312L312FCttTtt9898AY.20.0349
ORF1ab/nsp3312L312FCttTtt9292B.1.1600.002869
ORF1ab/nsp3312L312FCttTtt8383P.10.001308
ORF1ab/nsp3312L312FCttTtt8080B.1.4290.001882
ORF1ab/nsp3312L312FCttTtt7474AY.270.004789
ORF1ab/nsp3312L312FCttTtt7474B.1.3110.020319
ORF1ab/nsp3312L312FCttTtt6767AY.30.000666
ORF1ab/nsp3312L312FCttTtt6767B.1.1770.000882
ORF1ab/nsp3312L312FCttTtt6666AY.250.000397
ORF1ab/nsp3312L312FCttTtt5858B.1.2340.007653
ORF1ab/nsp3312L312FCttTtt3939C.36.30.022121
ORF1ab/nsp3312L312FCttTtt3636AY.140.003168
ORF1ab/nsp3312L312FCttTtt3535B.1.360.005107
ORF1ab/nsp3312L312FCttTtt3131AY.46.60.002238
ORF1ab/nsp3312L312FCttTtt2929B.1.2430.002018
ORF1ab/nsp3312L312FCttTtt2424B.1.1.1070.774194
ORF1ab/nsp3312L312FCttTtt2424C.370.002786
ORF1ab/nsp3312L312FCttTtt2222B.1.3510.000654
ORF1ab/nsp3312L312FCttTtt1818AY.340.001745
ORF1ab/nsp3312L312FCttTtt1717AY.1020.000451
ORF1ab/nsp3312L312FCttTtt1616B.1.1.5190.000635
ORF1ab/nsp3312L312FCttTtt1616B.1.2210.001137
ORF1ab/nsp3312L312FCttTtt1515AY.200.000583
ORF1ab/nsp3312L312FCttTtt1515B.1.1.4240.681818
ORF1ab/nsp3312L312FCttTtt1515B.1.3690.004278
ORF1ab/nsp3312L312FCttTtt1515B.1.5260.000353
ORF1ab/nsp3312L312FCttTtt1414AE.80.006846
ORF1ab/nsp3312L312FCttTtt1414AY.1190.000494
ORF1ab/nsp3312L312FCttTtt1414AY.260.000396
ORF1ab/nsp3312L312FCttTtt1414AY.46.10.014374
ORF1ab/nsp3312L312FCttTtt1414B.1.2580.000932
ORF1ab/nsp3312L312FCttTtt1313R.10.00117
ORF1ab/nsp3312L312FCttTtt1212B.1.6210.001062
ORF1ab/nsp3312L312FCttTtt1111B.1.1.500.007468
ORF1ab/nsp3312L312FCttTtt1111B.1.4160.013959
ORF1ab/nsp3312L312FCttTtt1111B.1.5950.002871
ORF1ab/nsp3312L312FCttTtt1010AY.1050.006431
ORF1ab/nsp3312L312FCttTtt1010AY.610.001048
ORF1ab/nsp3312L312FCttTtt99AY.46.40.001481
ORF1ab/nsp3312L312FCttTtt99P.20.00168
ORF1ab/nsp3312L312FCttTtt88AY.290.000126
ORF1ab/nsp3312L312FCttTtt88AY.750.000448
ORF1ab/nsp3312L312FCttTtt88B.1.177.620.009535
ORF1ab/nsp3312L312FCttTtt88B.1.36.90.025723
ORF1ab/nsp3312L312FCttTtt88P.1.70.002554
ORF1ab/nsp3312L312FCttTtt77AY.470.000218
ORF1ab/nsp3312L312FCttTtt77AY.60.000288
ORF1ab/nsp3312L312FCttTtt77AY.880.006189
ORF1ab/nsp3312L312FCttTtt77AY.98.10.000339
ORF1ab/nsp3312L312FCttTtt77B.1.177.860.001284
ORF1ab/nsp3312L312FCttTtt77B.1.2400.001509
ORF1ab/nsp3312L312FCttTtt77B.1.466.20.002739
ORF1ab/nsp3312L312FCttTtt77B.1.5960.00061
ORF1ab/nsp3312L312FCttTtt66A.2.5.10.028846
ORF1ab/nsp3312L312FCttTtt66AY.4.20.00013
ORF1ab/nsp3312L312FCttTtt66AY.99.20.000553
ORF1ab/nsp3312L312FCttTtt66B.1.214.20.003597
ORF1ab/nsp3312L312FCttTtt66B.1.30.015707
ORF1ab/nsp3312L312FCttTtt55A.190.04717
ORF1ab/nsp3312L312FCttTtt55AY.640.002976
ORF1ab/nsp3312L312FCttTtt55AY.810.00996
ORF1ab/nsp3312L312FCttTtt55B.1.1.2140.000277
ORF1ab/nsp3312L312FCttTtt55B.1.1.3060.002192
ORF1ab/nsp3312L312FCttTtt55B.1.2410.004058
ORF1ab/nsp3312L312FCttTtt55B.1.4700.007022
ORF1ab/nsp3312L312FCttTtt55D.20.000375
ORF1ab/nsp3312L312FCttTtt44AY.450.000487
ORF1ab/nsp3312L312FCttTtt44AY.50.000083
ORF1ab/nsp3312L312FCttTtt44AY.920.001149
ORF1ab/nsp3312L312FCttTtt44B.1.1.10.001307
ORF1ab/nsp3312L312FCttTtt44B.1.1.3110.001433
ORF1ab/nsp3312L312FCttTtt44B.1.1.5250.021858
ORF1ab/nsp3312L312FCttTtt44B.1.3490.002859
ORF1ab/nsp3312L312FCttTtt44B.1.5250.000453
ORF1ab/nsp3312L312FCttTtt44B.1.6120.01061
ORF1ab/nsp3312L312FCttTtt44B.1.617.30.01194
ORF1ab/nsp3312L312FCttTtt44B.1.6370.000292
ORF1ab/nsp3312L312FCttTtt44P.1.140.000191
ORF1ab/nsp3312L312FCttTtt44Q.30.00058
ORF1ab/nsp3312L312FCttTtt33A.2.5.20.004717
ORF1ab/nsp3312L312FCttTtt33AD.20.000657
ORF1ab/nsp3312L312FCttTtt33AP.10.004505
ORF1ab/nsp3312L312FCttTtt33AY.1070.001398
ORF1ab/nsp3312L312FCttTtt33AY.1180.000188
ORF1ab/nsp3312L312FCttTtt33AY.120.10.000963
ORF1ab/nsp3312L312FCttTtt33AY.1210.000406
ORF1ab/nsp3312L312FCttTtt33AY.360.000445
ORF1ab/nsp3312L312FCttTtt33AY.480.001395
ORF1ab/nsp3312L312FCttTtt33B.1.1.2180.023077
ORF1ab/nsp3312L312FCttTtt33B.1.1620.015075
ORF1ab/nsp3312L312FCttTtt33B.1.36.290.001552
ORF1ab/nsp3312L312FCttTtt33B.1.36.370.008333
ORF1ab/nsp3312L312FCttTtt33B.1.4000.001287
ORF1ab/nsp3312L312FCttTtt33B.1.5500.041096
ORF1ab/nsp3312L312FCttTtt33B.1.617.10.000387
ORF1ab/nsp3312L312FCttTtt22A.20.001324
ORF1ab/nsp3312L312FCttTtt22AY.1000.000092
ORF1ab/nsp3312L312FCttTtt22AY.1130.000285
ORF1ab/nsp3312L312FCttTtt22AY.1200.000074
ORF1ab/nsp3312L312FCttTtt22AY.190.002281
ORF1ab/nsp3312L312FCttTtt22AY.230.000139
ORF1ab/nsp3312L312FCttTtt22AY.4.50.000215
ORF1ab/nsp3312L312FCttTtt22AY.46.50.000397
ORF1ab/nsp3312L312FCttTtt22AY.540.000191
ORF1ab/nsp3312L312FCttTtt22AY.620.000871
ORF1ab/nsp3312L312FCttTtt22AY.680.000547
ORF1ab/nsp3312L312FCttTtt22AY.700.000417
ORF1ab/nsp3312L312FCttTtt22AY.75.10.000361
ORF1ab/nsp3312L312FCttTtt22B0.000256
ORF1ab/nsp3312L312FCttTtt22B.1.1.1570.001826
ORF1ab/nsp3312L312FCttTtt22B.1.1.2200.003717
ORF1ab/nsp3312L312FCttTtt22B.1.1.2220.000408
ORF1ab/nsp3312L312FCttTtt22B.1.1.2320.00363
ORF1ab/nsp3312L312FCttTtt22B.1.1.280.000622
ORF1ab/nsp3312L312FCttTtt22B.1.1.3480.001592
ORF1ab/nsp3312L312FCttTtt22B.1.1260.002551
ORF1ab/nsp3312L312FCttTtt22B.1.1270.004396
ORF1ab/nsp3312L312FCttTtt22B.1.1530.037736
ORF1ab/nsp3312L312FCttTtt22B.1.160.160.001859
ORF1ab/nsp3312L312FCttTtt22B.1.177.180.00232
ORF1ab/nsp3312L312FCttTtt22B.1.177.230.006472
ORF1ab/nsp3312L312FCttTtt22B.1.177.60.001953
ORF1ab/nsp3312L312FCttTtt22B.1.177.90.002663
ORF1ab/nsp3312L312FCttTtt22B.1.2360.004107
ORF1ab/nsp3312L312FCttTtt22B.1.2370.00995
ORF1ab/nsp3312L312FCttTtt22B.1.2980.004228
ORF1ab/nsp3312L312FCttTtt22B.1.3200.002491
ORF1ab/nsp3312L312FCttTtt22B.1.36.360.001204
ORF1ab/nsp3312L312FCttTtt22B.1.3800.013245
ORF1ab/nsp3312L312FCttTtt22B.1.5170.000854
ORF1ab/nsp3312L312FCttTtt22B.1.5640.000852
ORF1ab/nsp3312L312FCttTtt22P.1.150.000465
ORF1ab/nsp3312L312FCttTtt11A.2.20.001689
ORF1ab/nsp3312L312FCttTtt11A.230.010526
ORF1ab/nsp3312L312FCttTtt11AD.2.10.045455
ORF1ab/nsp3312L312FCttTtt11AE.40.043478
ORF1ab/nsp3312L312FCttTtt11AY.1060.000335
ORF1ab/nsp3312L312FCttTtt11AY.1170.000085
ORF1ab/nsp3312L312FCttTtt11AY.120.2.10.000498
ORF1ab/nsp3312L312FCttTtt11AY.16.10.00047
ORF1ab/nsp3312L312FCttTtt11AY.300.000396
ORF1ab/nsp3312L312FCttTtt11AY.320.000532
ORF1ab/nsp3312L312FCttTtt11AY.330.000067
ORF1ab/nsp3312L312FCttTtt11AY.380.000499
ORF1ab/nsp3312L312FCttTtt11AY.39.10.00004
ORF1ab/nsp3312L312FCttTtt11AY.5.40.000277
ORF1ab/nsp3312L312FCttTtt11AY.710.000475
ORF1ab/nsp3312L312FCttTtt11AY.740.000116
ORF1ab/nsp3312L312FCttTtt11AY.90.000068
ORF1ab/nsp3312L312FCttTtt11AY.9.10.000084
ORF1ab/nsp3312L312FCttTtt11AY.9.20.000037
ORF1ab/nsp3312L312FCttTtt11AY.910.00073
ORF1ab/nsp3312L312FCttTtt11AY.950.000761
ORF1ab/nsp3312L312FCttTtt11AY.970.001701
ORF1ab/nsp3312L312FCttTtt11AY.980.000079
ORF1ab/nsp3312L312FCttTtt11AZ.50.003509
ORF1ab/nsp3312L312FCttTtt11B.1.1.1010.01
ORF1ab/nsp3312L312FCttTtt11B.1.1.1530.001095
ORF1ab/nsp3312L312FCttTtt11B.1.1.2070.001182
ORF1ab/nsp3312L312FCttTtt11B.1.1.2690.001353
ORF1ab/nsp3312L312FCttTtt11B.1.1.270.00565
ORF1ab/nsp3312L312FCttTtt11B.1.1.2840.000107
ORF1ab/nsp3312L312FCttTtt11B.1.1.2890.002083
ORF1ab/nsp3312L312FCttTtt11B.1.1.2940.001266
ORF1ab/nsp3312L312FCttTtt11B.1.1.3050.003861
ORF1ab/nsp3312L312FCttTtt11B.1.1.3170.000412
ORF1ab/nsp3312L312FCttTtt11B.1.1.3180.000302
ORF1ab/nsp3312L312FCttTtt11B.1.1.3260.001761
ORF1ab/nsp3312L312FCttTtt11B.1.1.3690.000446
ORF1ab/nsp3312L312FCttTtt11B.1.1.370.000193
ORF1ab/nsp3312L312FCttTtt11B.1.1.3750.011905
ORF1ab/nsp3312L312FCttTtt11B.1.1.3980.003226
ORF1ab/nsp3312L312FCttTtt11B.1.1.4130.006897
ORF1ab/nsp3312L312FCttTtt11B.1.1.4160.000905
ORF1ab/nsp3312L312FCttTtt11B.1.1.4320.001266
ORF1ab/nsp3312L312FCttTtt11B.1.1030.019231
ORF1ab/nsp3312L312FCttTtt11B.1.1190.010526
ORF1ab/nsp3312L312FCttTtt11B.1.1390.000733
ORF1ab/nsp3312L312FCttTtt11B.1.1570.002985
ORF1ab/nsp3312L312FCttTtt11B.1.160.220.006757
ORF1ab/nsp3312L312FCttTtt11B.1.177.160.000664
ORF1ab/nsp3312L312FCttTtt11B.1.177.20.004545
ORF1ab/nsp3312L312FCttTtt11B.1.177.40.000211
ORF1ab/nsp3312L312FCttTtt11B.1.177.510.004566
ORF1ab/nsp3312L312FCttTtt11B.1.177.600.000218
ORF1ab/nsp3312L312FCttTtt11B.1.177.650.000665
ORF1ab/nsp3312L312FCttTtt11B.1.177.730.000566
ORF1ab/nsp3312L312FCttTtt11B.1.177.830.001481
ORF1ab/nsp3312L312FCttTtt11B.1.1790.003759
ORF1ab/nsp3312L312FCttTtt11B.1.1890.004292
ORF1ab/nsp3312L312FCttTtt11B.1.2320.000537
ORF1ab/nsp3312L312FCttTtt11B.1.2390.001221
ORF1ab/nsp3312L312FCttTtt11B.1.2650.001271
ORF1ab/nsp3312L312FCttTtt11B.1.36.100.004785
ORF1ab/nsp3312L312FCttTtt11B.1.36.180.00042
ORF1ab/nsp3312L312FCttTtt11B.1.36.310.001751
ORF1ab/nsp3312L312FCttTtt11B.1.36.350.002604
ORF1ab/nsp3312L312FCttTtt11B.1.3960.000706
ORF1ab/nsp3312L312FCttTtt11B.1.3990.001934
ORF1ab/nsp3312L312FCttTtt11B.1.4030.003268
ORF1ab/nsp3312L312FCttTtt11B.1.4270.00005
ORF1ab/nsp3312L312FCttTtt11B.1.4280.00102
ORF1ab/nsp3312L312FCttTtt11B.1.4330.003195
ORF1ab/nsp3312L312FCttTtt11B.1.4800.002488
ORF1ab/nsp3312L312FCttTtt11B.1.4970.000315
ORF1ab/nsp3312L312FCttTtt11B.1.5510.00129
ORF1ab/nsp3312L312FCttTtt11B.1.5620.018519
ORF1ab/nsp3312L312FCttTtt11B.1.5650.00081
ORF1ab/nsp3312L312FCttTtt11B.1.5750.000303
ORF1ab/nsp3312L312FCttTtt11B.1.575.10.002439
ORF1ab/nsp3312L312FCttTtt11B.1.5760.000907
ORF1ab/nsp3312L312FCttTtt11B.1.6090.000479
ORF1ab/nsp3312L312FCttTtt11B.1.6230.000536
ORF1ab/nsp3312L312FCttTtt11B.1.6260.005714
ORF1ab/nsp3312L312FCttTtt11B.1.6270.00202
ORF1ab/nsp3312L312FCttTtt11B.1.80.001972
ORF1ab/nsp3312L312FCttTtt11B.100.008264
ORF1ab/nsp3312L312FCttTtt11B.30.000831
ORF1ab/nsp3312L312FCttTtt11B.450.003831
ORF1ab/nsp3312L312FCttTtt11C.10.002392
ORF1ab/nsp3312L312FCttTtt11C.230.005814
ORF1ab/nsp3312L312FCttTtt11N.60.007092
ORF1ab/nsp3312L312FCttTtt11P.1.10.000318
ORF1ab/nsp3312L312FCttTtt11P.1.100.000269
ORF1ab/nsp3312L312FCttTtt11P.1.160.000374
ORF1ab/nsp3312L312FCttTtt11P.1.80.004785
ORF1ab/nsp3312L312FCttTtt11Q.10.000126
ORF1ab/nsp3312L312FCttTtt11Q.70.001111

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.