CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L1857F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31857L1857FL2675FnonsynCtcTtc191918288-8290

Details of the mutation L1857F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31857L1857FCtcTtc1919All0.000004
ORF1ab/nsp31857L1857FCtcTtc22AY.4.20.000043
ORF1ab/nsp31857L1857FCtcTtc22B.1.1.70.000002
ORF1ab/nsp31857L1857FCtcTtc22D.20.00015
ORF1ab/nsp31857L1857FCtcTtc110.055556
ORF1ab/nsp31857L1857FCtcTtc11AY.30.00001
ORF1ab/nsp31857L1857FCtcTtc11AY.40.000002
ORF1ab/nsp31857L1857FCtcTtc11AY.430.000004
ORF1ab/nsp31857L1857FCtcTtc11AY.540.000095
ORF1ab/nsp31857L1857FCtcTtc11B.10.000009
ORF1ab/nsp31857L1857FCtcTtc11B.1.177.440.000519
ORF1ab/nsp31857L1857FCtcTtc11B.1.20.000009
ORF1ab/nsp31857L1857FCtcTtc11B.1.2430.00007
ORF1ab/nsp31857L1857FCtcTtc11B.1.3960.000706
ORF1ab/nsp31857L1857FCtcTtc11B.1.4290.000024
ORF1ab/nsp31857L1857FCtcTtc11B.1.5760.000907
ORF1ab/nsp31857L1857FCtcTtc11B.1.5820.000491

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.