CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L1791F

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31791L1791FL2609FnonsynCtcTtc504150280.9974218090-8092
ORF1ab/nsp31791L1791FL2609FnonsynCtCTtT5041130.002578858090-8092

Details of the mutation L1791F within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31791L1791FCtcTtc50285041All0.000962
ORF1ab/nsp31791L1791FCtCTtT135041All0.000002
ORF1ab/nsp31791L1791FCtcTtc10041004B.1.1.70.000899
ORF1ab/nsp31791L1791FCtcTtc912912AY.40.001419
ORF1ab/nsp31791L1791FCtcTtc327327AY.99.10.507764
ORF1ab/nsp31791L1791FCtcTtc218218B.1.617.20.000821
ORF1ab/nsp31791L1791FCtcTtc205205B.1.258.170.021314
ORF1ab/nsp31791L1791FCtcTtc113113B.1.1770.001488
ORF1ab/nsp31791L1791FCtcTtc102102AY.1030.000633
ORF1ab/nsp31791L1791FCtcTtc9797B.520.979798
ORF1ab/nsp31791L1791FCtcTtc9595AY.430.000421
ORF1ab/nsp31791L1791FCtcTtc8787B.1.3510.002586
ORF1ab/nsp31791L1791FCtcTtc8686AY.30.000855
ORF1ab/nsp31791L1791FCtcTtc8484P.10.001323
ORF1ab/nsp31791L1791FCtcTtc7878B.1.20.000687
ORF1ab/nsp31791L1791FCtcTtc7474B.1.5260.001739
ORF1ab/nsp31791L1791FCtcTtc6969AY.250.000415
ORF1ab/nsp31791L1791FCtcTtc6666B.1.177.741
ORF1ab/nsp31791L1791FCtcTtc6363AY.440.000383
ORF1ab/nsp31791L1791FCtcTtc5252AY.340.005042
ORF1ab/nsp31791L1791FCtcTtc4848B.1.1.2220.009792
ORF1ab/nsp31791L1791FCtcTtc4242AY.1000.001932
ORF1ab/nsp31791L1791FCtcTtc4040XA0.888889
ORF1ab/nsp31791L1791FCtcTtc3939B.1.438.10.004183
ORF1ab/nsp31791L1791FCtcTtc3636B.1.4270.001818
ORF1ab/nsp31791L1791FCtcTtc3232B.1.4290.000753
ORF1ab/nsp31791L1791FCtcTtc3131AY.1020.000822
ORF1ab/nsp31791L1791FCtcTtc3131AY.4.20.000672
ORF1ab/nsp31791L1791FCtcTtc3030C.36.3.10.081522
ORF1ab/nsp31791L1791FCtcTtc2828B.10.000256
ORF1ab/nsp31791L1791FCtcTtc2828B.1.1.2140.001553
ORF1ab/nsp31791L1791FCtcTtc2828B.1.177.670.21374
ORF1ab/nsp31791L1791FCtcTtc2424B.1.10.000435
ORF1ab/nsp31791L1791FCtcTtc2424B.1.1.2160.021371
ORF1ab/nsp31791L1791FCtcTtc2424B.1.1600.000749
ORF1ab/nsp31791L1791FCtcTtc2323AY.260.000651
ORF1ab/nsp31791L1791FCtcTtc2222B.1.177.600.004806
ORF1ab/nsp31791L1791FCtcTtc2020P.1.140.000956
ORF1ab/nsp31791L1791FCtcTtc1818AZ.20.014778
ORF1ab/nsp31791L1791FCtcTtc1818B.1.6210.001593
ORF1ab/nsp31791L1791FCtcTtc1717AY.60.000699
ORF1ab/nsp31791L1791FCtcTtc1616B.1.2210.001137
ORF1ab/nsp31791L1791FCtcTtc1515AY.1040.029762
ORF1ab/nsp31791L1791FCtcTtc1515AY.290.000237
ORF1ab/nsp31791L1791FCtcTtc1414AY.90.000946
ORF1ab/nsp31791L1791FCtcTtc1414B.1.1.3110.005014
ORF1ab/nsp31791L1791FCtcTtc1414B.1.1.440.033735
ORF1ab/nsp31791L1791FCtcTtc1414B.1.1.5190.000556
ORF1ab/nsp31791L1791FCtcTtc1313B0.001662
ORF1ab/nsp31791L1791FCtcTtc1212AY.200.000466
ORF1ab/nsp31791L1791FCtcTtc1212AY.460.001249
ORF1ab/nsp31791L1791FCtcTtc1212AY.50.000248
ORF1ab/nsp31791L1791FCtCTtT1212B.1.177.60.011719
ORF1ab/nsp31791L1791FCtcTtc1212B.1.3690.003423
ORF1ab/nsp31791L1791FCtcTtc1111AY.98.10.000533
ORF1ab/nsp31791L1791FCtcTtc1111B.1.177.810.002083
ORF1ab/nsp31791L1791FCtcTtc1111B.1.177.860.002018
ORF1ab/nsp31791L1791FCtcTtc1111B.1.2430.000765
ORF1ab/nsp31791L1791FCtcTtc1010AY.1190.000353
ORF1ab/nsp31791L1791FCtcTtc1010AY.230.000697
ORF1ab/nsp31791L1791FCtcTtc1010AY.39.1.10.007246
ORF1ab/nsp31791L1791FCtcTtc1010AY.470.000311
ORF1ab/nsp31791L1791FCtcTtc1010B.1.360.001459
ORF1ab/nsp31791L1791FCtcTtc99AY.46.60.00065
ORF1ab/nsp31791L1791FCtcTtc99AY.750.000504
ORF1ab/nsp31791L1791FCtcTtc99AY.980.000711
ORF1ab/nsp31791L1791FCtcTtc99B.1.5750.002731
ORF1ab/nsp31791L1791FCtcTtc99B.1.5960.000784
ORF1ab/nsp31791L1791FCtcTtc88AY.1130.001139
ORF1ab/nsp31791L1791FCtcTtc88AY.330.000534
ORF1ab/nsp31791L1791FCtcTtc88AY.450.000973
ORF1ab/nsp31791L1791FCtcTtc88B.1.5250.000905
ORF1ab/nsp31791L1791FCtcTtc77AY.9.20.000257
ORF1ab/nsp31791L1791FCtcTtc77B.1.2580.000466
ORF1ab/nsp31791L1791FCtcTtc77B.1.4000.003003
ORF1ab/nsp31791L1791FCtcTtc66A.2.50.002994
ORF1ab/nsp31791L1791FCtcTtc66AY.1200.000223
ORF1ab/nsp31791L1791FCtcTtc66B.1.3960.004234
ORF1ab/nsp31791L1791FCtcTtc66B.1.4970.001889
ORF1ab/nsp31791L1791FCtcTtc66B.1.5880.00546
ORF1ab/nsp31791L1791FCtcTtc66B.1.6200.005676
ORF1ab/nsp31791L1791FCtcTtc55AY.1160.001434
ORF1ab/nsp31791L1791FCtcTtc55AY.1170.000423
ORF1ab/nsp31791L1791FCtcTtc55AY.3.10.000426
ORF1ab/nsp31791L1791FCtcTtc55AY.420.000201
ORF1ab/nsp31791L1791FCtcTtc55B.1.177.440.002595
ORF1ab/nsp31791L1791FCtcTtc55B.1.6370.000365
ORF1ab/nsp31791L1791FCtcTtc44AY.1180.000251
ORF1ab/nsp31791L1791FCtcTtc44AY.390.000099
ORF1ab/nsp31791L1791FCtcTtc44AY.610.000419
ORF1ab/nsp31791L1791FCtcTtc44AZ.30.006079
ORF1ab/nsp31791L1791FCtcTtc44B.1.1.1700.004988
ORF1ab/nsp31791L1791FCtcTtc44B.1.1.280.001245
ORF1ab/nsp31791L1791FCtcTtc44B.1.110.30.002874
ORF1ab/nsp31791L1791FCtcTtc44B.1.177.570.001124
ORF1ab/nsp31791L1791FCtcTtc44B.1.2360.008214
ORF1ab/nsp31791L1791FCtcTtc44C.370.000464
ORF1ab/nsp31791L1791FCtcTtc44P.1.100.001078
ORF1ab/nsp31791L1791FCtcTtc44R.10.00036
ORF1ab/nsp31791L1791FCtcTtc33AY.10.001187
ORF1ab/nsp31791L1791FCtcTtc33AY.130.000483
ORF1ab/nsp31791L1791FCtcTtc33AY.300.001187
ORF1ab/nsp31791L1791FCtcTtc33AY.39.10.000119
ORF1ab/nsp31791L1791FCtcTtc33AY.640.001786
ORF1ab/nsp31791L1791FCtcTtc33AY.700.000626
ORF1ab/nsp31791L1791FCtcTtc33AY.99.20.000276
ORF1ab/nsp31791L1791FCtcTtc33B.1.1.3060.001315
ORF1ab/nsp31791L1791FCtcTtc33B.1.1.3260.005282
ORF1ab/nsp31791L1791FCtcTtc33B.1.1.3480.002389
ORF1ab/nsp31791L1791FCtcTtc33B.1.1.370.000579
ORF1ab/nsp31791L1791FCtcTtc33B.1.1.700.001023
ORF1ab/nsp31791L1791FCtcTtc33B.1.177.210.000229
ORF1ab/nsp31791L1791FCtcTtc33B.1.177.520.005272
ORF1ab/nsp31791L1791FCtcTtc33B.1.177.70.000495
ORF1ab/nsp31791L1791FCtcTtc33B.1.5170.001281
ORF1ab/nsp31791L1791FCtcTtc33B.1.5950.000783
ORF1ab/nsp31791L1791FCtcTtc33C.350.002322
ORF1ab/nsp31791L1791FCtcTtc33Q.40.001364
ORF1ab/nsp31791L1791FCtcTtc22AL.10.025974
ORF1ab/nsp31791L1791FCtcTtc22AY.1210.000271
ORF1ab/nsp31791L1791FCtcTtc22AY.23.10.000835
ORF1ab/nsp31791L1791FCtcTtc22AY.34.10.00102
ORF1ab/nsp31791L1791FCtcTtc22AY.370.000632
ORF1ab/nsp31791L1791FCtcTtc22AY.46.40.000329
ORF1ab/nsp31791L1791FCtcTtc22AY.5.30.000675
ORF1ab/nsp31791L1791FCtcTtc22AY.540.000191
ORF1ab/nsp31791L1791FCtcTtc22AY.590.001059
ORF1ab/nsp31791L1791FCtcTtc22AY.620.000871
ORF1ab/nsp31791L1791FCtcTtc22AY.900.001369
ORF1ab/nsp31791L1791FCtcTtc22B.1.1.10.000653
ORF1ab/nsp31791L1791FCtcTtc22B.1.1.1280.014184
ORF1ab/nsp31791L1791FCtcTtc22B.1.1.1410.004024
ORF1ab/nsp31791L1791FCtcTtc22B.1.1.2280.006098
ORF1ab/nsp31791L1791FCtcTtc22B.1.1.3290.007692
ORF1ab/nsp31791L1791FCtCTtT12B.1.1.620.027027
ORF1ab/nsp31791L1791FCtcTtc12B.1.1.620.027027
ORF1ab/nsp31791L1791FCtcTtc22B.1.1.630.000772
ORF1ab/nsp31791L1791FCtcTtc22B.1.177.110.003396
ORF1ab/nsp31791L1791FCtcTtc22B.1.177.40.000422
ORF1ab/nsp31791L1791FCtcTtc22B.1.177.400.010309
ORF1ab/nsp31791L1791FCtcTtc22B.1.1990.008264
ORF1ab/nsp31791L1791FCtcTtc22B.1.2130.029851
ORF1ab/nsp31791L1791FCtcTtc22B.1.2340.000264
ORF1ab/nsp31791L1791FCtcTtc22B.1.258.30.00335
ORF1ab/nsp31791L1791FCtcTtc22B.1.3130.013158
ORF1ab/nsp31791L1791FCtcTtc22B.1.3490.00143
ORF1ab/nsp31791L1791FCtcTtc22B.1.36.170.000988
ORF1ab/nsp31791L1791FCtcTtc22B.1.36.90.006431
ORF1ab/nsp31791L1791FCtcTtc22B.1.3600.025316
ORF1ab/nsp31791L1791FCtcTtc22B.1.3980.005952
ORF1ab/nsp31791L1791FCtcTtc22B.1.5650.001621
ORF1ab/nsp31791L1791FCtcTtc22B.1.617.10.000258
ORF1ab/nsp31791L1791FCtcTtc22B.1.6230.001073
ORF1ab/nsp31791L1791FCtcTtc22B.1.6250.004706
ORF1ab/nsp31791L1791FCtcTtc22C.36.10.008299
ORF1ab/nsp31791L1791FCtcTtc22P.1.150.000465
ORF1ab/nsp31791L1791FCtcTtc11A.2.20.001689
ORF1ab/nsp31791L1791FCtcTtc11A.23.10.000704
ORF1ab/nsp31791L1791FCtcTtc11A.50.001923
ORF1ab/nsp31791L1791FCtcTtc11AD.20.000219
ORF1ab/nsp31791L1791FCtcTtc11AY.100.00053
ORF1ab/nsp31791L1791FCtcTtc11AY.1050.000643
ORF1ab/nsp31791L1791FCtcTtc11AY.1080.001103
ORF1ab/nsp31791L1791FCtcTtc11AY.1090.00074
ORF1ab/nsp31791L1791FCtcTtc11AY.1110.000183
ORF1ab/nsp31791L1791FCtcTtc11AY.1140.000231
ORF1ab/nsp31791L1791FCtcTtc11AY.120.000316
ORF1ab/nsp31791L1791FCtcTtc11AY.270.000065
ORF1ab/nsp31791L1791FCtcTtc11AY.320.000532
ORF1ab/nsp31791L1791FCtcTtc11AY.360.000148
ORF1ab/nsp31791L1791FCtcTtc11AY.4.2.10.000149
ORF1ab/nsp31791L1791FCtcTtc11AY.4.50.000107
ORF1ab/nsp31791L1791FCtcTtc11AY.530.000288
ORF1ab/nsp31791L1791FCtcTtc11AY.690.000187
ORF1ab/nsp31791L1791FCtcTtc11AY.710.000475
ORF1ab/nsp31791L1791FCtcTtc11AY.730.000665
ORF1ab/nsp31791L1791FCtcTtc11AY.820.001357
ORF1ab/nsp31791L1791FCtcTtc11AY.850.000427
ORF1ab/nsp31791L1791FCtcTtc11AY.870.000833
ORF1ab/nsp31791L1791FCtcTtc11AY.970.001701
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.1290.009174
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.1940.00495
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.1980.001468
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.2630.001558
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.2840.000107
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.2960.018182
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3010.001179
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3050.003861
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3090.005848
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3180.000302
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.330.000421
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3440.010753
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3660.015873
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3680.003086
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3690.000446
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3700.012658
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.3720.000689
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.4160.000905
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.4230.0625
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.4860.001577
ORF1ab/nsp31791L1791FCtcTtc11B.1.1.5230.001563
ORF1ab/nsp31791L1791FCtcTtc11B.1.1280.000635
ORF1ab/nsp31791L1791FCtcTtc11B.1.1460.004237
ORF1ab/nsp31791L1791FCtcTtc11B.1.1580.02381
ORF1ab/nsp31791L1791FCtcTtc11B.1.1700.00431
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.160.000664
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.420.000894
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.500.004695
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.650.000665
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.730.000566
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.770.000726
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.80.000752
ORF1ab/nsp31791L1791FCtcTtc11B.1.177.820.000477
ORF1ab/nsp31791L1791FCtcTtc11B.1.2320.000537
ORF1ab/nsp31791L1791FCtcTtc11B.1.2400.000216
ORF1ab/nsp31791L1791FCtcTtc11B.1.258.110.000396
ORF1ab/nsp31791L1791FCtcTtc11B.1.2800.007143
ORF1ab/nsp31791L1791FCtcTtc11B.1.3110.000275
ORF1ab/nsp31791L1791FCtcTtc11B.1.36.180.00042
ORF1ab/nsp31791L1791FCtcTtc11B.1.36.310.001751
ORF1ab/nsp31791L1791FCtcTtc11B.1.36.360.000602
ORF1ab/nsp31791L1791FCtcTtc11B.1.3710.001122
ORF1ab/nsp31791L1791FCtcTtc11B.1.3910.001127
ORF1ab/nsp31791L1791FCtcTtc11B.1.4150.014286
ORF1ab/nsp31791L1791FCtcTtc11B.1.4250.002994
ORF1ab/nsp31791L1791FCtcTtc11B.1.4560.003268
ORF1ab/nsp31791L1791FCtcTtc11B.1.466.20.000391
ORF1ab/nsp31791L1791FCtcTtc11B.1.4790.038462
ORF1ab/nsp31791L1791FCtcTtc11B.1.4990.00105
ORF1ab/nsp31791L1791FCtcTtc11B.1.5090.000866
ORF1ab/nsp31791L1791FCtcTtc11B.1.5460.003704
ORF1ab/nsp31791L1791FCtcTtc11B.1.5610.000397
ORF1ab/nsp31791L1791FCtcTtc11B.1.5640.000426
ORF1ab/nsp31791L1791FCtcTtc11B.1.564.10.001577
ORF1ab/nsp31791L1791FCtcTtc11B.1.5760.000907
ORF1ab/nsp31791L1791FCtcTtc11B.1.6090.000479
ORF1ab/nsp31791L1791FCtcTtc11B.1.6280.000352
ORF1ab/nsp31791L1791FCtcTtc11B.30.000831
ORF1ab/nsp31791L1791FCtcTtc11B.4.10.018868
ORF1ab/nsp31791L1791FCtcTtc11B.560.028571
ORF1ab/nsp31791L1791FCtcTtc11B.6.60.000889
ORF1ab/nsp31791L1791FCtcTtc11C.180.002591
ORF1ab/nsp31791L1791FCtcTtc11C.230.005814
ORF1ab/nsp31791L1791FCtcTtc11D.20.000075
ORF1ab/nsp31791L1791FCtcTtc11N.30.005814
ORF1ab/nsp31791L1791FCtcTtc11P.1.170.000162
ORF1ab/nsp31791L1791FCtcTtc11P.20.000187
ORF1ab/nsp31791L1791FCtcTtc11Q.30.000145
ORF1ab/nsp31791L1791FCtcTtc11Q.80.000165
ORF1ab/nsp31791L1791FCtcTtc11W.20.004831

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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