CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L1746L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31746L1746LL2564LsynctTctA9688120.8388437955-7957
ORF1ab/nsp31746L1746LL2564LsynctTctC9681160.1198357955-7957
ORF1ab/nsp31746L1746LL2564LsynctTctG968400.04132237955-7957

Details of the mutation L1746L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31746L1746LctTctA812968All0.000155
ORF1ab/nsp31746L1746LctTctC116968All0.000022
ORF1ab/nsp31746L1746LctTctG40968All0.000008
ORF1ab/nsp31746L1746LctTctA770770AU.10.974684
ORF1ab/nsp31746L1746LctTctC8182B.1.1.70.000073
ORF1ab/nsp31746L1746LctTctG182B.1.1.70.000001
ORF1ab/nsp31746L1746LctTctG3536AY.430.000155
ORF1ab/nsp31746L1746LctTctC136AY.430.000004
ORF1ab/nsp31746L1746LctTctA1214B.10.00011
ORF1ab/nsp31746L1746LctTctC114B.10.000009
ORF1ab/nsp31746L1746LctTctG114B.10.000009
ORF1ab/nsp31746L1746LctTctA99B.1.466.20.003521
ORF1ab/nsp31746L1746LctTctC78B.1.1770.000092
ORF1ab/nsp31746L1746LctTctA18B.1.1770.000013
ORF1ab/nsp31746L1746LctTctA88Q.30.00116
ORF1ab/nsp31746L1746LctTctA36B.1.617.20.000011
ORF1ab/nsp31746L1746LctTctC26B.1.617.20.000008
ORF1ab/nsp31746L1746LctTctG16B.1.617.20.000004
ORF1ab/nsp31746L1746LctTctC44AY.40.000006
ORF1ab/nsp31746L1746LctTctC33AY.250.000018
ORF1ab/nsp31746L1746LctTctA33B.1.2600.010033
ORF1ab/nsp31746L1746LctTctC23B.1.5230.004902
ORF1ab/nsp31746L1746LctTctA13B.1.5230.002451
ORF1ab/nsp31746L1746LctTctC33P.10.000047
ORF1ab/nsp31746L1746LctTctC22AY.420.00008
ORF1ab/nsp31746L1746LctTctA22B.1.4590.008163
ORF1ab/nsp31746L1746LctTctC22P.1.140.000096
ORF1ab/nsp31746L1746LctTctC11AY.1030.000006
ORF1ab/nsp31746L1746LctTctC11AY.4.20.000022
ORF1ab/nsp31746L1746LctTctA11AY.440.000006
ORF1ab/nsp31746L1746LctTctC11AY.470.000031
ORF1ab/nsp31746L1746LctTctC11B.1.10.000018
ORF1ab/nsp31746L1746LctTctG11B.1.1.1530.001095
ORF1ab/nsp31746L1746LctTctC11B.1.1.270.00565
ORF1ab/nsp31746L1746LctTctC11B.1.1.510.001718
ORF1ab/nsp31746L1746LctTctC11B.1.1.5210.005348
ORF1ab/nsp31746L1746LctTctC11B.1.20.000009
ORF1ab/nsp31746L1746LctTctA11B.1.2220.001692
ORF1ab/nsp31746L1746LctTctA11B.1.5750.000303
ORF1ab/nsp31746L1746LctTctG11B.1.5960.000087

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.