CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = L1244L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31244L1244LL2062LsynctTctC2241710.7633936449-6451
ORF1ab/nsp31244L1244LL2062LsynctTctA224430.1919646449-6451
ORF1ab/nsp31244L1244LL2062LsynctTctG22480.03571436449-6451
ORF1ab/nsp31244L1244LL2062LsynCtTTtG22410.004464296449-6451
ORF1ab/nsp31244L1244LL2062LsynCtTTtA22410.004464296449-6451

Details of the mutation L1244L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31244L1244LctTctC171224All0.000033
ORF1ab/nsp31244L1244LctTctA43224All0.000008
ORF1ab/nsp31244L1244LctTctG8224All0.000002
ORF1ab/nsp31244L1244LCtTTtG1224All0
ORF1ab/nsp31244L1244LCtTTtA1224All0
ORF1ab/nsp31244L1244LctTctC5965AY.40.000092
ORF1ab/nsp31244L1244LctTctA665AY.40.000009
ORF1ab/nsp31244L1244LctTctC1220B.1.1.70.000011
ORF1ab/nsp31244L1244LctTctA520B.1.1.70.000004
ORF1ab/nsp31244L1244LctTctG220B.1.1.70.000002
ORF1ab/nsp31244L1244LCtTTtG120B.1.1.70.000001
ORF1ab/nsp31244L1244LctTctC1515AY.90.001014
ORF1ab/nsp31244L1244LctTctC1313AY.420.000523
ORF1ab/nsp31244L1244LctTctC1313B.1.4270.000656
ORF1ab/nsp31244L1244LctTctA1011AY.290.000158
ORF1ab/nsp31244L1244LctTctC111AY.290.000016
ORF1ab/nsp31244L1244LctTctC99B.1.258.220.024
ORF1ab/nsp31244L1244LctTctA58B.1.20.000044
ORF1ab/nsp31244L1244LctTctC38B.1.20.000026
ORF1ab/nsp31244L1244LctTctC55B.1.6200.00473
ORF1ab/nsp31244L1244LctTctC24AY.1030.000012
ORF1ab/nsp31244L1244LctTctA24AY.1030.000012
ORF1ab/nsp31244L1244LctTctA34AY.440.000018
ORF1ab/nsp31244L1244LctTctC14AY.440.000006
ORF1ab/nsp31244L1244LctTctC44B.1.617.20.000015
ORF1ab/nsp31244L1244LctTctC33AY.1200.000112
ORF1ab/nsp31244L1244LctTctC23AY.390.000049
ORF1ab/nsp31244L1244LctTctA13AY.390.000025
ORF1ab/nsp31244L1244LctTctC33AY.430.000013
ORF1ab/nsp31244L1244LctTctA33P.1.140.000143
ORF1ab/nsp31244L1244LctTctC22AY.1010.000981
ORF1ab/nsp31244L1244LctTctC22AY.250.000012
ORF1ab/nsp31244L1244LctTctC12AY.4.20.000022
ORF1ab/nsp31244L1244LctTctA12AY.4.20.000022
ORF1ab/nsp31244L1244LctTctC22AY.750.000112
ORF1ab/nsp31244L1244LctTctC22AY.9.10.000167
ORF1ab/nsp31244L1244LctTctG12B0.000128
ORF1ab/nsp31244L1244LctTctC12B0.000128
ORF1ab/nsp31244L1244LctTctG12B.1.1770.000013
ORF1ab/nsp31244L1244LctTctC12B.1.1770.000013
ORF1ab/nsp31244L1244LctTctA22B.1.36.90.006431
ORF1ab/nsp31244L1244LctTctC12B.1.438.10.000107
ORF1ab/nsp31244L1244LctTctG12B.1.438.10.000107
ORF1ab/nsp31244L1244LctTctC22B.1.5250.000226
ORF1ab/nsp31244L1244LctTctA110.055556
ORF1ab/nsp31244L1244LctTctC11AY.1020.000027
ORF1ab/nsp31244L1244LctTctC11AY.1180.000063
ORF1ab/nsp31244L1244LctTctC11AY.1190.000035
ORF1ab/nsp31244L1244LctTctC11AY.140.000088
ORF1ab/nsp31244L1244LctTctC11AY.230.00007
ORF1ab/nsp31244L1244LctTctC11AY.39.10.00004
ORF1ab/nsp31244L1244LctTctA11AY.4.50.000107
ORF1ab/nsp31244L1244LctTctC11AY.550.000917
ORF1ab/nsp31244L1244LctTctC11AY.870.000833
ORF1ab/nsp31244L1244LctTctG11AY.98.10.000048
ORF1ab/nsp31244L1244LctTctC11B.1.10.000018
ORF1ab/nsp31244L1244LctTctC11B.1.1.1690.018182
ORF1ab/nsp31244L1244LctTctC11B.1.1.3260.001761
ORF1ab/nsp31244L1244LCtTTtA11B.1.1.460.004367
ORF1ab/nsp31244L1244LctTctG11B.1.177.860.000183
ORF1ab/nsp31244L1244LctTctA11B.1.2580.000067
ORF1ab/nsp31244L1244LctTctA11B.1.36.340.021277
ORF1ab/nsp31244L1244LctTctG11B.1.6210.000089
ORF1ab/nsp31244L1244LctTctA11C.370.000116
ORF1ab/nsp31244L1244LctTctC11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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