CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = K530T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3530K530TK1348TnonsynaAgaCg26220.8461544307-4309
ORF1ab/nsp3530K530TK1348TnonsynaAGaCC2620.07692314307-4309
ORF1ab/nsp3530K530TK1348TnonsynaAGaCT2620.07692314307-4309

Details of the mutation K530T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3530K530TaAgaCg2226All0.000004
ORF1ab/nsp3530K530TaAGaCC226All0
ORF1ab/nsp3530K530TaAGaCT226All0
ORF1ab/nsp3530K530TaAgaCg66AY.200.000233
ORF1ab/nsp3530K530TaAgaCg55B.1.1.70.000004
ORF1ab/nsp3530K530TaAgaCg33AY.40.000005
ORF1ab/nsp3530K530TaAgaCg33AY.420.000121
ORF1ab/nsp3530K530TaAGaCT12AY.30.00001
ORF1ab/nsp3530K530TaAGaCC12AY.30.00001
ORF1ab/nsp3530K530TaAGaCT12AY.3.10.000085
ORF1ab/nsp3530K530TaAGaCC12AY.3.10.000085
ORF1ab/nsp3530K530TaAgaCg11AY.1030.000006
ORF1ab/nsp3530K530TaAgaCg11AY.230.00007
ORF1ab/nsp3530K530TaAgaCg11B.10.000009
ORF1ab/nsp3530K530TaAgaCg11B.1.10.000018
ORF1ab/nsp3530K530TaAgaCg11B.1.20.000009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.