CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = I1192T

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31192I1192TI2010TnonsynaTaaCa1864186416293-6295

Details of the mutation I1192T within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31192I1192TaTaaCa18641864All0.000357
ORF1ab/nsp31192I1192TaTaaCa10011001AY.1030.006215
ORF1ab/nsp31192I1192TaTaaCa169169AY.40.000263
ORF1ab/nsp31192I1192TaTaaCa154154B.1.617.20.00058
ORF1ab/nsp31192I1192TaTaaCa138138B.1.1821
ORF1ab/nsp31192I1192TaTaaCa9090B.1.1.70.000081
ORF1ab/nsp31192I1192TaTaaCa2626AY.430.000115
ORF1ab/nsp31192I1192TaTaaCa2222B.1.1.2310.068111
ORF1ab/nsp31192I1192TaTaaCa2020AY.420.000805
ORF1ab/nsp31192I1192TaTaaCa1717R.10.00153
ORF1ab/nsp31192I1192TaTaaCa1616AY.540.001526
ORF1ab/nsp31192I1192TaTaaCa1515AY.250.00009
ORF1ab/nsp31192I1192TaTaaCa1515B.1.258.110.005945
ORF1ab/nsp31192I1192TaTaaCa1313B.10.000119
ORF1ab/nsp31192I1192TaTaaCa1111B.1.2430.000765
ORF1ab/nsp31192I1192TaTaaCa88AY.440.000049
ORF1ab/nsp31192I1192TaTaaCa88B.1.1.2940.010127
ORF1ab/nsp31192I1192TaTaaCa88B.1.6370.000585
ORF1ab/nsp31192I1192TaTaaCa77AY.1020.000186
ORF1ab/nsp31192I1192TaTaaCa77AY.1180.000439
ORF1ab/nsp31192I1192TaTaaCa77AY.4.20.000152
ORF1ab/nsp31192I1192TaTaaCa77P.1.140.000335
ORF1ab/nsp31192I1192TaTaaCa66AY.260.00017
ORF1ab/nsp31192I1192TaTaaCa55AY.1200.000186
ORF1ab/nsp31192I1192TaTaaCa55B.1.10.000091
ORF1ab/nsp31192I1192TaTaaCa44AY.30.00004
ORF1ab/nsp31192I1192TaTaaCa44B.1.1.5190.000159
ORF1ab/nsp31192I1192TaTaaCa44B.1.1600.000125
ORF1ab/nsp31192I1192TaTaaCa44B.1.20.000035
ORF1ab/nsp31192I1192TaTaaCa44B.1.3110.001098
ORF1ab/nsp31192I1192TaTaaCa44B.1.4290.000094
ORF1ab/nsp31192I1192TaTaaCa33AY.1000.000138
ORF1ab/nsp31192I1192TaTaaCa33AY.290.000047
ORF1ab/nsp31192I1192TaTaaCa33AY.470.000093
ORF1ab/nsp31192I1192TaTaaCa33AY.610.000314
ORF1ab/nsp31192I1192TaTaaCa33B.1.1770.00004
ORF1ab/nsp31192I1192TaTaaCa22AY.390.000049
ORF1ab/nsp31192I1192TaTaaCa22AY.460.000208
ORF1ab/nsp31192I1192TaTaaCa22AY.740.000231
ORF1ab/nsp31192I1192TaTaaCa22AY.99.20.000184
ORF1ab/nsp31192I1192TaTaaCa22B.1.1.3260.003521
ORF1ab/nsp31192I1192TaTaaCa22P.10.000032
ORF1ab/nsp31192I1192TaTaaCa11A.2.50.000499
ORF1ab/nsp31192I1192TaTaaCa11A.2.5.20.001572
ORF1ab/nsp31192I1192TaTaaCa11A.50.001923
ORF1ab/nsp31192I1192TaTaaCa11AD.20.000219
ORF1ab/nsp31192I1192TaTaaCa11AM.40.003571
ORF1ab/nsp31192I1192TaTaaCa11AY.100.00053
ORF1ab/nsp31192I1192TaTaaCa11AY.1170.000085
ORF1ab/nsp31192I1192TaTaaCa11AY.160.00038
ORF1ab/nsp31192I1192TaTaaCa11AY.29.10.000221
ORF1ab/nsp31192I1192TaTaaCa11AY.330.000067
ORF1ab/nsp31192I1192TaTaaCa11AY.340.000097
ORF1ab/nsp31192I1192TaTaaCa11AY.450.000122
ORF1ab/nsp31192I1192TaTaaCa11AY.46.20.000635
ORF1ab/nsp31192I1192TaTaaCa11AY.46.40.000165
ORF1ab/nsp31192I1192TaTaaCa11AY.590.00053
ORF1ab/nsp31192I1192TaTaaCa11AY.75.10.00018
ORF1ab/nsp31192I1192TaTaaCa11AY.90.000068
ORF1ab/nsp31192I1192TaTaaCa11AY.9.20.000037
ORF1ab/nsp31192I1192TaTaaCa11AY.920.000287
ORF1ab/nsp31192I1192TaTaaCa11B.1.1.80.003584
ORF1ab/nsp31192I1192TaTaaCa11B.1.160.120.00641
ORF1ab/nsp31192I1192TaTaaCa11B.1.177.120.000152
ORF1ab/nsp31192I1192TaTaaCa11B.1.177.620.001192
ORF1ab/nsp31192I1192TaTaaCa11B.1.1990.004132
ORF1ab/nsp31192I1192TaTaaCa11B.1.2370.004975
ORF1ab/nsp31192I1192TaTaaCa11B.1.2580.000067
ORF1ab/nsp31192I1192TaTaaCa11B.1.3510.00003
ORF1ab/nsp31192I1192TaTaaCa11B.1.351.20.000303
ORF1ab/nsp31192I1192TaTaaCa11B.1.360.000146
ORF1ab/nsp31192I1192TaTaaCa11B.1.4270.00005
ORF1ab/nsp31192I1192TaTaaCa11B.1.6210.000089
ORF1ab/nsp31192I1192TaTaaCa11C.2.10.006667
ORF1ab/nsp31192I1192TaTaaCa11C.360.000911
ORF1ab/nsp31192I1192TaTaaCa11D.20.000075
ORF1ab/nsp31192I1192TaTaaCa11N.50.001767
ORF1ab/nsp31192I1192TaTaaCa11P.1.40.000977
ORF1ab/nsp31192I1192TaTaaCa11P.1.80.004785
ORF1ab/nsp31192I1192TaTaaCa11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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