CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = G76G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp376G76GG894GsynggCggT109010640.9761472945-2947
ORF1ab/nsp376G76GG894GsynggCggA1090200.01834862945-2947
ORF1ab/nsp376G76GG894GsynggCggG109060.005504592945-2947

Details of the mutation G76G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp376G76GggCggT10641090All0.000204
ORF1ab/nsp376G76GggCggA201090All0.000004
ORF1ab/nsp376G76GggCggG61090All0.000001
ORF1ab/nsp376G76GggCggT193199B.1.1.70.000173
ORF1ab/nsp376G76GggCggG3199B.1.1.70.000003
ORF1ab/nsp376G76GggCggA3199B.1.1.70.000003
ORF1ab/nsp376G76GggCggT124124P.10.001953
ORF1ab/nsp376G76GggCggT9191B.1.20.000801
ORF1ab/nsp376G76GggCggT7676B.1.4690.274368
ORF1ab/nsp376G76GggCggT7272B.1.4060.436364
ORF1ab/nsp376G76GggCggT5960AY.40.000092
ORF1ab/nsp376G76GggCggA160AY.40.000002
ORF1ab/nsp376G76GggCggT5253B.1.617.20.000196
ORF1ab/nsp376G76GggCggA153B.1.617.20.000004
ORF1ab/nsp376G76GggCggT4849B.1.5250.005432
ORF1ab/nsp376G76GggCggA149B.1.5250.000113
ORF1ab/nsp376G76GggCggT3535AY.250.000211
ORF1ab/nsp376G76GggCggT2626AY.440.000158
ORF1ab/nsp376G76GggCggT2122AY.430.000093
ORF1ab/nsp376G76GggCggA122AY.430.000004
ORF1ab/nsp376G76GggCggT2122B.1.1.700.007162
ORF1ab/nsp376G76GggCggA122B.1.1.700.000341
ORF1ab/nsp376G76GggCggT2021AY.1020.00053
ORF1ab/nsp376G76GggCggA121AY.1020.000027
ORF1ab/nsp376G76GggCggT2020AY.20.007123
ORF1ab/nsp376G76GggCggT1717B.10.000156
ORF1ab/nsp376G76GggCggT1011B.1.10.000181
ORF1ab/nsp376G76GggCggG111B.1.10.000018
ORF1ab/nsp376G76GggCggT1010B.1.1600.000312
ORF1ab/nsp376G76GggCggT99AY.1030.000056
ORF1ab/nsp376G76GggCggT99B.1.3510.000268
ORF1ab/nsp376G76GggCggT88B.1.1.3110.002865
ORF1ab/nsp376G76GggCggT88B.1.1.4320.010127
ORF1ab/nsp376G76GggCggA56AY.240.002155
ORF1ab/nsp376G76GggCggT16AY.240.000431
ORF1ab/nsp376G76GggCggT66AY.4.20.00013
ORF1ab/nsp376G76GggCggT66B.1.6370.000438
ORF1ab/nsp376G76GggCggT55AY.30.00005
ORF1ab/nsp376G76GggCggT55AY.50.000103
ORF1ab/nsp376G76GggCggT44AY.1200.000149
ORF1ab/nsp376G76GggCggT44AY.1210.000541
ORF1ab/nsp376G76GggCggT44AY.330.000267
ORF1ab/nsp376G76GggCggT44AY.4.2.10.000596
ORF1ab/nsp376G76GggCggT44B.1.1770.000053
ORF1ab/nsp376G76GggCggT44C.370.000464
ORF1ab/nsp376G76GggCggT33AY.140.000264
ORF1ab/nsp376G76GggCggT33AY.220.006276
ORF1ab/nsp376G76GggCggT33AY.9.10.000251
ORF1ab/nsp376G76GggCggT33B.1.2430.000209
ORF1ab/nsp376G76GggCggT33B.1.3320.01049
ORF1ab/nsp376G76GggCggT33B.1.4290.000071
ORF1ab/nsp376G76GggCggT33B.1.5260.000071
ORF1ab/nsp376G76GggCggT33P.1.140.000143
ORF1ab/nsp376G76GggCggT22AY.1000.000092
ORF1ab/nsp376G76GggCggT22AY.1080.002205
ORF1ab/nsp376G76GggCggT22AY.1130.000285
ORF1ab/nsp376G76GggCggT22AY.290.000032
ORF1ab/nsp376G76GggCggT22AY.420.00008
ORF1ab/nsp376G76GggCggT22AY.590.001059
ORF1ab/nsp376G76GggCggT22AY.60.000082
ORF1ab/nsp376G76GggCggT22AY.920.000575
ORF1ab/nsp376G76GggCggA22B.1.1.2840.000215
ORF1ab/nsp376G76GggCggT22B.1.1.5190.000079
ORF1ab/nsp376G76GggCggG22B.1.2340.000264
ORF1ab/nsp376G76GggCggT22B.1.5960.000174
ORF1ab/nsp376G76GggCggT22D.20.00015
ORF1ab/nsp376G76GggCggT22P.1.120.000968
ORF1ab/nsp376G76GggCggA110.055556
ORF1ab/nsp376G76GggCggT11AY.1180.000063
ORF1ab/nsp376G76GggCggT11AY.200.000039
ORF1ab/nsp376G76GggCggT11AY.230.00007
ORF1ab/nsp376G76GggCggT11AY.29.10.000221
ORF1ab/nsp376G76GggCggT11AY.300.000396
ORF1ab/nsp376G76GggCggT11AY.340.000097
ORF1ab/nsp376G76GggCggT11AY.39.10.00004
ORF1ab/nsp376G76GggCggT11AY.410.000294
ORF1ab/nsp376G76GggCggT11AY.540.000095
ORF1ab/nsp376G76GggCggT11AY.610.000105
ORF1ab/nsp376G76GggCggT11AY.710.000475
ORF1ab/nsp376G76GggCggT11AY.910.00073
ORF1ab/nsp376G76GggCggT11AY.98.10.000048
ORF1ab/nsp376G76GggCggT11B.1.1.2320.001815
ORF1ab/nsp376G76GggCggT11B.1.1.2430.004082
ORF1ab/nsp376G76GggCggT11B.1.1.280.000311
ORF1ab/nsp376G76GggCggT11B.1.1.2940.001266
ORF1ab/nsp376G76GggCggT11B.1.1.3170.000412
ORF1ab/nsp376G76GggCggT11B.1.1.390.00051
ORF1ab/nsp376G76GggCggT11B.1.1.4340.000349
ORF1ab/nsp376G76GggCggT11B.1.1.560.017857
ORF1ab/nsp376G76GggCggT11B.1.1.630.000386
ORF1ab/nsp376G76GggCggT11B.1.160.280.002924
ORF1ab/nsp376G76GggCggT11B.1.177.240.001295
ORF1ab/nsp376G76GggCggT11B.1.177.270.009434
ORF1ab/nsp376G76GggCggA11B.1.177.440.000519
ORF1ab/nsp376G76GggCggT11B.1.177.500.004695
ORF1ab/nsp376G76GggCggT11B.1.2210.000071
ORF1ab/nsp376G76GggCggT11B.1.2390.001221
ORF1ab/nsp376G76GggCggT11B.1.2400.000216
ORF1ab/nsp376G76GggCggT11B.1.258.170.000104
ORF1ab/nsp376G76GggCggT11B.1.264.10.047619
ORF1ab/nsp376G76GggCggT11B.1.351.50.0006
ORF1ab/nsp376G76GggCggT11B.1.3610.001289
ORF1ab/nsp376G76GggCggT11B.1.3960.000706
ORF1ab/nsp376G76GggCggT11B.1.438.10.000107
ORF1ab/nsp376G76GggCggT11B.1.5240.001406
ORF1ab/nsp376G76GggCggT11B.1.6210.000089
ORF1ab/nsp376G76GggCggA11B.310.003731
ORF1ab/nsp376G76GggCggT11P.1.10.000318
ORF1ab/nsp376G76GggCggT11P.1.150.000232
ORF1ab/nsp376G76GggCggA11Q.30.000145
ORF1ab/nsp376G76GggCggT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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