CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = G76C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp376G76CG894CnonsynGgcTgc116211600.9982792945-2947
ORF1ab/nsp376G76CG894CnonsynGgCTgT116220.001721172945-2947

Details of the mutation G76C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp376G76CGgcTgc11601162All0.000222
ORF1ab/nsp376G76CGgCTgT21162All0
ORF1ab/nsp376G76CGgcTgc503503B.1.1.70.00045
ORF1ab/nsp376G76CGgcTgc182182B.1.20.001603
ORF1ab/nsp376G76CGgcTgc5252P.1.10.016518
ORF1ab/nsp376G76CGgcTgc3434B.1.617.20.000128
ORF1ab/nsp376G76CGgcTgc2929AY.1030.00018
ORF1ab/nsp376G76CGgcTgc2929AY.40.000045
ORF1ab/nsp376G76CGgcTgc2424AY.250.000144
ORF1ab/nsp376G76CGgcTgc2222Q.80.003628
ORF1ab/nsp376G76CGgcTgc2121P.10.000331
ORF1ab/nsp376G76CGgcTgc2020AY.430.000089
ORF1ab/nsp376G76CGgcTgc1717B.10.000156
ORF1ab/nsp376G76CGgcTgc1616AY.120.10.005136
ORF1ab/nsp376G76CGgcTgc1313AY.1020.000345
ORF1ab/nsp376G76CGgcTgc1111AY.350.002564
ORF1ab/nsp376G76CGgcTgc1010AY.50.000206
ORF1ab/nsp376G76CGgcTgc99B.1.2360.01848
ORF1ab/nsp376G76CGgcTgc88AY.30.00008
ORF1ab/nsp376G76CGgcTgc77AY.200.000272
ORF1ab/nsp376G76CGgcTgc77AY.440.000043
ORF1ab/nsp376G76CGgcTgc77B.1.6300.036649
ORF1ab/nsp376G76CGgcTgc66AY.260.00017
ORF1ab/nsp376G76CGgcTgc46AY.99.20.000369
ORF1ab/nsp376G76CGgCTgT26AY.99.20.000184
ORF1ab/nsp376G76CGgcTgc55AY.280.009452
ORF1ab/nsp376G76CGgcTgc55AY.330.000334
ORF1ab/nsp376G76CGgcTgc55AY.420.000201
ORF1ab/nsp376G76CGgcTgc55AY.610.000524
ORF1ab/nsp376G76CGgcTgc55AY.710.002375
ORF1ab/nsp376G76CGgcTgc55AY.750.00028
ORF1ab/nsp376G76CGgcTgc55AY.98.10.000242
ORF1ab/nsp376G76CGgcTgc55B.1.10.000091
ORF1ab/nsp376G76CGgcTgc44AY.1180.000251
ORF1ab/nsp376G76CGgcTgc44AY.270.000259
ORF1ab/nsp376G76CGgcTgc44AY.570.002625
ORF1ab/nsp376G76CGgcTgc33B.1.3510.000089
ORF1ab/nsp376G76CGgcTgc33B.1.5260.000071
ORF1ab/nsp376G76CGgcTgc33P.1.160.001122
ORF1ab/nsp376G76CGgcTgc22AY.1060.00067
ORF1ab/nsp376G76CGgcTgc22AY.1190.000071
ORF1ab/nsp376G76CGgcTgc22AY.130.000322
ORF1ab/nsp376G76CGgcTgc22AY.3.10.000171
ORF1ab/nsp376G76CGgcTgc22AY.390.000049
ORF1ab/nsp376G76CGgcTgc22AY.450.000243
ORF1ab/nsp376G76CGgcTgc22AY.460.000208
ORF1ab/nsp376G76CGgcTgc22AY.7.20.001119
ORF1ab/nsp376G76CGgcTgc22B.1.177.200.003035
ORF1ab/nsp376G76CGgcTgc22B.1.177.410.005
ORF1ab/nsp376G76CGgcTgc22B.1.4290.000047
ORF1ab/nsp376G76CGgcTgc22C.370.000232
ORF1ab/nsp376G76CGgcTgc22D.20.00015
ORF1ab/nsp376G76CGgcTgc22P.20.000373
ORF1ab/nsp376G76CGgcTgc22Q.10.000253
ORF1ab/nsp376G76CGgcTgc11A0.000387
ORF1ab/nsp376G76CGgcTgc11A.210.00277
ORF1ab/nsp376G76CGgcTgc11A.30.002096
ORF1ab/nsp376G76CGgcTgc11AY.1140.000231
ORF1ab/nsp376G76CGgcTgc11AY.230.00007
ORF1ab/nsp376G76CGgcTgc11AY.300.000396
ORF1ab/nsp376G76CGgcTgc11AY.4.20.000022
ORF1ab/nsp376G76CGgcTgc11AY.46.10.001027
ORF1ab/nsp376G76CGgcTgc11AY.5.30.000337
ORF1ab/nsp376G76CGgcTgc11AY.520.000814
ORF1ab/nsp376G76CGgcTgc11AY.580.000907
ORF1ab/nsp376G76CGgcTgc11AY.590.00053
ORF1ab/nsp376G76CGgcTgc11AY.730.000665
ORF1ab/nsp376G76CGgcTgc11AY.75.10.00018
ORF1ab/nsp376G76CGgcTgc11AY.910.00073
ORF1ab/nsp376G76CGgcTgc11B.1.1.2140.000055
ORF1ab/nsp376G76CGgcTgc11B.1.1.2260.005814
ORF1ab/nsp376G76CGgcTgc11B.1.1.280.000311
ORF1ab/nsp376G76CGgcTgc11B.1.1.3170.000412
ORF1ab/nsp376G76CGgcTgc11B.1.1.5190.00004
ORF1ab/nsp376G76CGgcTgc11B.1.1.700.000341
ORF1ab/nsp376G76CGgcTgc11B.1.110.30.000718
ORF1ab/nsp376G76CGgcTgc11B.1.1770.000013
ORF1ab/nsp376G76CGgcTgc11B.1.177.160.000664
ORF1ab/nsp376G76CGgcTgc11B.1.2580.000067
ORF1ab/nsp376G76CGgcTgc11B.1.3400.004292
ORF1ab/nsp376G76CGgcTgc11B.1.3610.001289
ORF1ab/nsp376G76CGgcTgc11B.1.3750.00082
ORF1ab/nsp376G76CGgcTgc11B.1.390.003906
ORF1ab/nsp376G76CGgcTgc11B.1.4270.00005
ORF1ab/nsp376G76CGgcTgc11B.1.5160.001957
ORF1ab/nsp376G76CGgcTgc11B.1.6100.003546
ORF1ab/nsp376G76CGgcTgc11B.1.621.10.000506
ORF1ab/nsp376G76CGgcTgc11P.1.150.000232
ORF1ab/nsp376G76CGgcTgc11P.1.70.000319
ORF1ab/nsp376G76CGgcTgc11P.50.013699
ORF1ab/nsp376G76CGgcTgc11Q.50.016949
ORF1ab/nsp376G76CGgcTgc11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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