CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = G282S

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3282G282SG1100SnonsynGgtAgt114411410.9973783563-3565
ORF1ab/nsp3282G282SG1100SnonsynGgTAgC114410.0008741263563-3565
ORF1ab/nsp3282G282SG1100SnonsynGGTTCA114410.0008741263563-3565
ORF1ab/nsp3282G282SG1100SnonsynGGTTCG114410.0008741263563-3565

Details of the mutation G282S within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3282G282SGgtAgt11411144All0.000218
ORF1ab/nsp3282G282SGGTTCG11144All0
ORF1ab/nsp3282G282SGGTTCA11144All0
ORF1ab/nsp3282G282SGgTAgC11144All0
ORF1ab/nsp3282G282SGgtAgt253254B.1.1.70.000226
ORF1ab/nsp3282G282SGgTAgC1254B.1.1.70.000001
ORF1ab/nsp3282G282SGgtAgt225225AY.40.00035
ORF1ab/nsp3282G282SGgtAgt118118AY.30.001174
ORF1ab/nsp3282G282SGgtAgt4646B.1.20.000405
ORF1ab/nsp3282G282SGgtAgt3939B.1.617.20.000147
ORF1ab/nsp3282G282SGgtAgt3535B.1.1.2840.003759
ORF1ab/nsp3282G282SGgtAgt3232AY.440.000195
ORF1ab/nsp3282G282SGgtAgt3131AY.1030.000192
ORF1ab/nsp3282G282SGgtAgt2828B.1.4290.000659
ORF1ab/nsp3282G282SGgtAgt2626P.10.00041
ORF1ab/nsp3282G282SGgtAgt2323AY.50.000475
ORF1ab/nsp3282G282SGgtAgt1919AY.430.000084
ORF1ab/nsp3282G282SGgtAgt1717Q.10.002148
ORF1ab/nsp3282G282SGgtAgt1616B.1.177.190.02289
ORF1ab/nsp3282G282SGgtAgt1515B.1.1.4160.013575
ORF1ab/nsp3282G282SGgtAgt1414AY.250.000084
ORF1ab/nsp3282G282SGgtAgt1212B.1.160.270.181818
ORF1ab/nsp3282G282SGgtAgt1212B.1.6370.000877
ORF1ab/nsp3282G282SGgtAgt1111AY.200.000428
ORF1ab/nsp3282G282SGgtAgt1111P.1.140.000526
ORF1ab/nsp3282G282SGgtAgt1010AY.390.000247
ORF1ab/nsp3282G282SGgtAgt1010AY.4.20.000217
ORF1ab/nsp3282G282SGgtAgt88AY.260.000226
ORF1ab/nsp3282G282SGgtAgt88AY.60.000329
ORF1ab/nsp3282G282SGgtAgt66B.10.000055
ORF1ab/nsp3282G282SGgtAgt66B.1.10.000109
ORF1ab/nsp3282G282SGgtAgt66B.1.2340.000792
ORF1ab/nsp3282G282SGgtAgt66C.370.000696
ORF1ab/nsp3282G282SGgtAgt55B.1.2320.002687
ORF1ab/nsp3282G282SGgtAgt44AY.1000.000184
ORF1ab/nsp3282G282SGgtAgt44AY.290.000063
ORF1ab/nsp3282G282SGgtAgt44B.1.1770.000053
ORF1ab/nsp3282G282SGgtAgt44B.1.617.10.000516
ORF1ab/nsp3282G282SGgtAgt33AY.29.10.000662
ORF1ab/nsp3282G282SGgtAgt33AY.470.000093
ORF1ab/nsp3282G282SGgtAgt33B.1.2430.000209
ORF1ab/nsp3282G282SGgtAgt33B.1.3460.003932
ORF1ab/nsp3282G282SGgtAgt33B.1.3510.000089
ORF1ab/nsp3282G282SGgtAgt33B.1.4270.000151
ORF1ab/nsp3282G282SGgtAgt22A.23.10.001408
ORF1ab/nsp3282G282SGgtAgt22AY.330.000134
ORF1ab/nsp3282G282SGgtAgt22AY.75.10.000361
ORF1ab/nsp3282G282SGgtAgt22B.1.1260.002551
ORF1ab/nsp3282G282SGGTTCG12B.1.1570.002985
ORF1ab/nsp3282G282SGGTTCA12B.1.1570.002985
ORF1ab/nsp3282G282SGgtAgt22B.1.1600.000062
ORF1ab/nsp3282G282SGgtAgt22B.1.2210.000142
ORF1ab/nsp3282G282SGgtAgt22B.1.3770.009132
ORF1ab/nsp3282G282SGgtAgt22B.1.5260.000047
ORF1ab/nsp3282G282SGgtAgt22B.1.5960.000174
ORF1ab/nsp3282G282SGgtAgt22D.20.00015
ORF1ab/nsp3282G282SGgtAgt11AY.1160.000287
ORF1ab/nsp3282G282SGgtAgt11AY.1210.000135
ORF1ab/nsp3282G282SGgtAgt11AY.16.10.00047
ORF1ab/nsp3282G282SGgtAgt11AY.230.00007
ORF1ab/nsp3282G282SGgtAgt11AY.34.10.00051
ORF1ab/nsp3282G282SGgtAgt11AY.350.000233
ORF1ab/nsp3282G282SGgtAgt11AY.420.00004
ORF1ab/nsp3282G282SGgtAgt11AY.580.000907
ORF1ab/nsp3282G282SGgtAgt11AY.620.000436
ORF1ab/nsp3282G282SGgtAgt11AY.650.000533
ORF1ab/nsp3282G282SGgtAgt11AY.690.000187
ORF1ab/nsp3282G282SGgtAgt11AY.790.001211
ORF1ab/nsp3282G282SGgtAgt11AY.930.000273
ORF1ab/nsp3282G282SGgtAgt11B0.000128
ORF1ab/nsp3282G282SGgtAgt11B.1.1.2220.000204
ORF1ab/nsp3282G282SGgtAgt11B.1.1.250.000569
ORF1ab/nsp3282G282SGgtAgt11B.1.1.370.000193
ORF1ab/nsp3282G282SGgtAgt11B.1.1.4200.001006
ORF1ab/nsp3282G282SGgtAgt11B.1.1.4330.001425
ORF1ab/nsp3282G282SGgtAgt11B.1.1.500.000679
ORF1ab/nsp3282G282SGgtAgt11B.1.1.5190.00004
ORF1ab/nsp3282G282SGgtAgt11B.1.160.310.008065
ORF1ab/nsp3282G282SGgtAgt11B.1.160.320.004292
ORF1ab/nsp3282G282SGgtAgt11B.1.177.550.002331
ORF1ab/nsp3282G282SGgtAgt11B.1.177.810.000189
ORF1ab/nsp3282G282SGgtAgt11B.1.177.90.001332
ORF1ab/nsp3282G282SGgtAgt11B.1.2400.000216
ORF1ab/nsp3282G282SGgtAgt11B.1.2580.000067
ORF1ab/nsp3282G282SGgtAgt11B.1.258.170.000104
ORF1ab/nsp3282G282SGgtAgt11B.1.2600.003344
ORF1ab/nsp3282G282SGgtAgt11B.1.3660.004878
ORF1ab/nsp3282G282SGgtAgt11B.1.4000.000429
ORF1ab/nsp3282G282SGgtAgt11B.1.4990.00105
ORF1ab/nsp3282G282SGgtAgt11B.1.5760.000907
ORF1ab/nsp3282G282SGgtAgt11B.1.5950.000261
ORF1ab/nsp3282G282SGgtAgt11B.270.015385
ORF1ab/nsp3282G282SGgtAgt11N.50.001767
ORF1ab/nsp3282G282SGgtAgt11P.1.130.000898
ORF1ab/nsp3282G282SGgtAgt11P.1.150.000232

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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