CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = G251G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3251G251GG1069GsynggAggG5334070.7636023470-3472
ORF1ab/nsp3251G251GG1069GsynggAggC533760.1425893470-3472
ORF1ab/nsp3251G251GG1069GsynggAggT533500.09380863470-3472

Details of the mutation G251G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3251G251GggAggG407533All0.000078
ORF1ab/nsp3251G251GggAggC76533All0.000015
ORF1ab/nsp3251G251GggAggT50533All0.00001
ORF1ab/nsp3251G251GggAggG7479B.1.617.20.000279
ORF1ab/nsp3251G251GggAggT579B.1.617.20.000019
ORF1ab/nsp3251G251GggAggG6767AY.1020.001776
ORF1ab/nsp3251G251GggAggG6467AY.40.0001
ORF1ab/nsp3251G251GggAggC367AY.40.000005
ORF1ab/nsp3251G251GggAggG1739B.1.1.70.000015
ORF1ab/nsp3251G251GggAggC1239B.1.1.70.000011
ORF1ab/nsp3251G251GggAggT1039B.1.1.70.000009
ORF1ab/nsp3251G251GggAggC1730AY.250.000102
ORF1ab/nsp3251G251GggAggG1330AY.250.000078
ORF1ab/nsp3251G251GggAggG2828B.1.1.5070.243478
ORF1ab/nsp3251G251GggAggG1418B.10.000128
ORF1ab/nsp3251G251GggAggT318B.10.000027
ORF1ab/nsp3251G251GggAggC118B.10.000009
ORF1ab/nsp3251G251GggAggC1516AY.30.000149
ORF1ab/nsp3251G251GggAggG116AY.30.00001
ORF1ab/nsp3251G251GggAggG1212AY.98.10.000581
ORF1ab/nsp3251G251GggAggG1212B.1.9.40.07362
ORF1ab/nsp3251G251GggAggG611AY.440.000037
ORF1ab/nsp3251G251GggAggT511AY.440.00003
ORF1ab/nsp3251G251GggAggG1111B.1.4270.000555
ORF1ab/nsp3251G251GggAggC79AY.1030.000043
ORF1ab/nsp3251G251GggAggT19AY.1030.000006
ORF1ab/nsp3251G251GggAggG19AY.1030.000006
ORF1ab/nsp3251G251GggAggG69AY.50.000124
ORF1ab/nsp3251G251GggAggT39AY.50.000062
ORF1ab/nsp3251G251GggAggT57B.1.10.000091
ORF1ab/nsp3251G251GggAggG17B.1.10.000018
ORF1ab/nsp3251G251GggAggC17B.1.10.000018
ORF1ab/nsp3251G251GggAggC36B.1.20.000026
ORF1ab/nsp3251G251GggAggG26B.1.20.000018
ORF1ab/nsp3251G251GggAggT16B.1.20.000009
ORF1ab/nsp3251G251GggAggG550.277778
ORF1ab/nsp3251G251GggAggC45AY.260.000113
ORF1ab/nsp3251G251GggAggG15AY.260.000028
ORF1ab/nsp3251G251GggAggG55AY.99.20.000461
ORF1ab/nsp3251G251GggAggG55B.40.011038
ORF1ab/nsp3251G251GggAggG55P.1.140.000239
ORF1ab/nsp3251G251GggAggG44AY.1000.000184
ORF1ab/nsp3251G251GggAggG44AY.390.000099
ORF1ab/nsp3251G251GggAggG44B.1.1.2540.044944
ORF1ab/nsp3251G251GggAggC44B.1.2430.000278
ORF1ab/nsp3251G251GggAggT34B.1.5960.000261
ORF1ab/nsp3251G251GggAggC14B.1.5960.000087
ORF1ab/nsp3251G251GggAggG33C.290.1875
ORF1ab/nsp3251G251GggAggG22AY.1160.000574
ORF1ab/nsp3251G251GggAggT12AY.1180.000063
ORF1ab/nsp3251G251GggAggG12AY.1180.000063
ORF1ab/nsp3251G251GggAggG22AY.230.000139
ORF1ab/nsp3251G251GggAggG12AY.430.000004
ORF1ab/nsp3251G251GggAggT12AY.430.000004
ORF1ab/nsp3251G251GggAggG22AY.690.000373
ORF1ab/nsp3251G251GggAggG22AY.840.000875
ORF1ab/nsp3251G251GggAggT22B.1.1.5190.000079
ORF1ab/nsp3251G251GggAggG22B.1.4290.000047
ORF1ab/nsp3251G251GggAggG22B.1.4990.002101
ORF1ab/nsp3251G251GggAggG22B.1.5090.001732
ORF1ab/nsp3251G251GggAggT22B.1.5640.000852
ORF1ab/nsp3251G251GggAggG22C.370.000232
ORF1ab/nsp3251G251GggAggC22P.10.000032
ORF1ab/nsp3251G251GggAggT11AY.1140.000231
ORF1ab/nsp3251G251GggAggC11AY.130.000161
ORF1ab/nsp3251G251GggAggG11AY.3.10.000085
ORF1ab/nsp3251G251GggAggC11AY.34.10.00051
ORF1ab/nsp3251G251GggAggC11AY.350.000233
ORF1ab/nsp3251G251GggAggG11AY.4.20.000022
ORF1ab/nsp3251G251GggAggG11AY.450.000122
ORF1ab/nsp3251G251GggAggG11AY.46.20.000635
ORF1ab/nsp3251G251GggAggT11AY.46.60.000072
ORF1ab/nsp3251G251GggAggT11AY.470.000031
ORF1ab/nsp3251G251GggAggT11AY.60.000041
ORF1ab/nsp3251G251GggAggG11AY.70.000196
ORF1ab/nsp3251G251GggAggG11AY.75.10.00018
ORF1ab/nsp3251G251GggAggG11AY.9.20.000037
ORF1ab/nsp3251G251GggAggG11B.1.1.2360.006897
ORF1ab/nsp3251G251GggAggG11B.1.1.2840.000107
ORF1ab/nsp3251G251GggAggT11B.1.1.3060.000438
ORF1ab/nsp3251G251GggAggG11B.1.1.4340.000349
ORF1ab/nsp3251G251GggAggG11B.1.1.4480.002033
ORF1ab/nsp3251G251GggAggG11B.1.1.4580.041667
ORF1ab/nsp3251G251GggAggG11B.1.1.630.000386
ORF1ab/nsp3251G251GggAggC11B.1.1600.000031
ORF1ab/nsp3251G251GggAggG11B.1.1770.000013
ORF1ab/nsp3251G251GggAggT11B.1.177.550.002331
ORF1ab/nsp3251G251GggAggG11B.1.2210.000071
ORF1ab/nsp3251G251GggAggG11B.1.3400.004292
ORF1ab/nsp3251G251GggAggG11B.1.3510.00003
ORF1ab/nsp3251G251GggAggT11B.1.36.280.005747
ORF1ab/nsp3251G251GggAggC11B.1.36.380.001642
ORF1ab/nsp3251G251GggAggG11B.1.4250.002994
ORF1ab/nsp3251G251GggAggG11B.1.5260.000024
ORF1ab/nsp3251G251GggAggG11B.1.5990.00365
ORF1ab/nsp3251G251GggAggC11B.1.617.10.000129
ORF1ab/nsp3251G251GggAggG11B.1.6280.000352
ORF1ab/nsp3251G251GggAggG11P.1.150.000232
ORF1ab/nsp3251G251GggAggG11P.1.170.000162
ORF1ab/nsp3251G251GggAggT11P.1.70.000319
ORF1ab/nsp3251G251GggAggG11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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