CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = G171V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3171G171VG989VnonsyngGtgTt503350290.9992053230-3232
ORF1ab/nsp3171G171VG989VnonsyngGTgTC503320.0003973773230-3232
ORF1ab/nsp3171G171VG989VnonsyngGTgTA503320.0003973773230-3232

Details of the mutation G171V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3171G171VgGtgTt50295033All0.000962
ORF1ab/nsp3171G171VgGTgTA25033All0
ORF1ab/nsp3171G171VgGTgTC25033All0
ORF1ab/nsp3171G171VgGtgTt23272327B.1.5170.993595
ORF1ab/nsp3171G171VgGtgTt360360AY.40.00056
ORF1ab/nsp3171G171VgGtgTt340342B.1.1.70.000304
ORF1ab/nsp3171G171VgGTgTA2342B.1.1.70.000002
ORF1ab/nsp3171G171VgGtgTt255255AY.650.135928
ORF1ab/nsp3171G171VgGtgTt196196B.1.617.20.000738
ORF1ab/nsp3171G171VgGtgTt190190B.1.517.11
ORF1ab/nsp3171G171VgGtgTt172172B.1.20.001515
ORF1ab/nsp3171G171VgGtgTt144144B.1.3750.118033
ORF1ab/nsp3171G171VgGtgTt135135B.10.001237
ORF1ab/nsp3171G171VgGtgTt123123AY.1200.004573
ORF1ab/nsp3171G171VgGtgTt6969AY.440.00042
ORF1ab/nsp3171G171VgGtgTt6565AY.430.000288
ORF1ab/nsp3171G171VgGtgTt6262AY.710.029454
ORF1ab/nsp3171G171VgGtgTt3535B.1.10.000635
ORF1ab/nsp3171G171VgGtgTt3232B.1.1.5190.001271
ORF1ab/nsp3171G171VgGtgTt2929AY.30.000288
ORF1ab/nsp3171G171VgGtgTt2626A.10.007328
ORF1ab/nsp3171G171VgGtgTt2525P.10.000394
ORF1ab/nsp3171G171VgGtgTt2020AY.390.000494
ORF1ab/nsp3171G171VgGtgTt1919AY.1210.002571
ORF1ab/nsp3171G171VgGtgTt1818B.1.1600.000561
ORF1ab/nsp3171G171VgGtgTt1818B.1.360.002626
ORF1ab/nsp3171G171VgGtgTt1313AY.250.000078
ORF1ab/nsp3171G171VgGtgTt1212AY.200.000466
ORF1ab/nsp3171G171VgGtgTt1111AY.320.005857
ORF1ab/nsp3171G171VgGtgTt1111AY.700.002294
ORF1ab/nsp3171G171VgGtgTt1010B.1.177.850.054348
ORF1ab/nsp3171G171VgGtgTt99B.1.1770.000119
ORF1ab/nsp3171G171VgGtgTt88B.1.2430.000557
ORF1ab/nsp3171G171VgGtgTt77B.1.5260.000165
ORF1ab/nsp3171G171VgGtgTt77D.20.000525
ORF1ab/nsp3171G171VgGtgTt66AY.1020.000159
ORF1ab/nsp3171G171VgGtgTt66AY.1030.000037
ORF1ab/nsp3171G171VgGtgTt66AY.130.000966
ORF1ab/nsp3171G171VgGtgTt66AY.4.50.000645
ORF1ab/nsp3171G171VgGtgTt66B.1.5460.022222
ORF1ab/nsp3171G171VgGtgTt55AY.290.000079
ORF1ab/nsp3171G171VgGtgTt55AY.450.000608
ORF1ab/nsp3171G171VgGtgTt55AY.460.00052
ORF1ab/nsp3171G171VgGtgTt55AY.470.000156
ORF1ab/nsp3171G171VgGtgTt55AY.50.000103
ORF1ab/nsp3171G171VgGtgTt55AY.610.000524
ORF1ab/nsp3171G171VgGtgTt55AY.75.10.000902
ORF1ab/nsp3171G171VgGtgTt55B.1.4090.003906
ORF1ab/nsp3171G171VgGtgTt55B.1.6370.000365
ORF1ab/nsp3171G171VgGtgTt55P.1.140.000239
ORF1ab/nsp3171G171VgGtgTt55P.20.000933
ORF1ab/nsp3171G171VgGtgTt44AY.330.000267
ORF1ab/nsp3171G171VgGtgTt44AY.370.001264
ORF1ab/nsp3171G171VgGtgTt44AY.46.50.000794
ORF1ab/nsp3171G171VgGtgTt44AY.690.000747
ORF1ab/nsp3171G171VgGtgTt44AY.790.004843
ORF1ab/nsp3171G171VgGtgTt44AY.900.002738
ORF1ab/nsp3171G171VgGtgTt44B.1.2580.000266
ORF1ab/nsp3171G171VgGtgTt44B.1.5960.000349
ORF1ab/nsp3171G171VgGtgTt33AY.270.000194
ORF1ab/nsp3171G171VgGtgTt33AY.4.20.000065
ORF1ab/nsp3171G171VgGtgTt33AY.750.000168
ORF1ab/nsp3171G171VgGtgTt33AY.90.000203
ORF1ab/nsp3171G171VgGtgTt33B.1.1.3330.003229
ORF1ab/nsp3171G171VgGtgTt33B.1.1.3690.001339
ORF1ab/nsp3171G171VgGtgTt33B.1.1.4340.001046
ORF1ab/nsp3171G171VgGtgTt33B.1.1490.010274
ORF1ab/nsp3171G171VgGtgTt33B.1.177.810.000568
ORF1ab/nsp3171G171VgGtgTt33B.1.2210.000213
ORF1ab/nsp3171G171VgGtgTt33B.1.3510.000089
ORF1ab/nsp3171G171VgGtgTt33B.1.4270.000151
ORF1ab/nsp3171G171VgGtgTt33B.1.4730.057692
ORF1ab/nsp3171G171VgGtgTt33B.1.5950.000783
ORF1ab/nsp3171G171VgGtgTt33B.1.617.10.000387
ORF1ab/nsp3171G171VgGtgTt33B.1.6210.000266
ORF1ab/nsp3171G171VgGtgTt33P.1.130.002695
ORF1ab/nsp3171G171VgGtgTt22A0.000774
ORF1ab/nsp3171G171VgGtgTt22AY.100.00106
ORF1ab/nsp3171G171VgGtgTt22AY.160.000759
ORF1ab/nsp3171G171VgGtgTt22AY.230.000139
ORF1ab/nsp3171G171VgGtgTt22AY.240.000862
ORF1ab/nsp3171G171VgGtgTt22AY.340.000194
ORF1ab/nsp3171G171VgGtgTt22AY.420.00008
ORF1ab/nsp3171G171VgGtgTt22AY.60.000082
ORF1ab/nsp3171G171VgGtgTt22AY.600.001876
ORF1ab/nsp3171G171VgGtgTt22AY.9.10.000167
ORF1ab/nsp3171G171VgGtgTt22AY.9.20.000073
ORF1ab/nsp3171G171VgGtgTt22B.1.1.1860.006873
ORF1ab/nsp3171G171VgGtgTt22B.1.1.2220.000408
ORF1ab/nsp3171G171VgGtgTt22B.1.1.2690.002706
ORF1ab/nsp3171G171VgGtgTt22B.1.1.330.000842
ORF1ab/nsp3171G171VgGtgTt22B.1.2100.004264
ORF1ab/nsp3171G171VgGtgTt22B.1.243.20.028986
ORF1ab/nsp3171G171VgGtgTt22B.1.3620.003082
ORF1ab/nsp3171G171VgGtgTt22B.1.3780.013699
ORF1ab/nsp3171G171VgGtgTt22B.1.4000.000858
ORF1ab/nsp3171G171VgGtgTt22B.1.5580.009132
ORF1ab/nsp3171G171VgGtgTt22B.1.5810.018868
ORF1ab/nsp3171G171VgGtgTt12B.290.003509
ORF1ab/nsp3171G171VgGTgTC12B.290.003509
ORF1ab/nsp3171G171VgGTgTC12B.400.000364
ORF1ab/nsp3171G171VgGtgTt12B.400.000364
ORF1ab/nsp3171G171VgGtgTt22C.370.000232
ORF1ab/nsp3171G171VgGtgTt11A.210.00277
ORF1ab/nsp3171G171VgGtgTt11A.230.010526
ORF1ab/nsp3171G171VgGtgTt11AY.1000.000046
ORF1ab/nsp3171G171VgGtgTt11AY.1100.000113
ORF1ab/nsp3171G171VgGtgTt11AY.1140.000231
ORF1ab/nsp3171G171VgGtgTt11AY.1190.000035
ORF1ab/nsp3171G171VgGtgTt11AY.120.10.000321
ORF1ab/nsp3171G171VgGtgTt11AY.140.000088
ORF1ab/nsp3171G171VgGtgTt11AY.16.10.00047
ORF1ab/nsp3171G171VgGtgTt11AY.190.00114
ORF1ab/nsp3171G171VgGtgTt11AY.3.10.000085
ORF1ab/nsp3171G171VgGtgTt11AY.4.2.10.000149
ORF1ab/nsp3171G171VgGtgTt11AY.4.40.000409
ORF1ab/nsp3171G171VgGtgTt11AY.410.000294
ORF1ab/nsp3171G171VgGtgTt11AY.46.10.001027
ORF1ab/nsp3171G171VgGtgTt11AY.46.60.000072
ORF1ab/nsp3171G171VgGtgTt11AY.5.30.000337
ORF1ab/nsp3171G171VgGtgTt11AY.5.40.000277
ORF1ab/nsp3171G171VgGtgTt11AY.530.000288
ORF1ab/nsp3171G171VgGtgTt11AY.590.00053
ORF1ab/nsp3171G171VgGtgTt11AY.7.10.000113
ORF1ab/nsp3171G171VgGtgTt11AY.870.000833
ORF1ab/nsp3171G171VgGtgTt11AY.880.000884
ORF1ab/nsp3171G171VgGtgTt11AY.890.004902
ORF1ab/nsp3171G171VgGtgTt11AY.920.000287
ORF1ab/nsp3171G171VgGtgTt11AY.950.000761
ORF1ab/nsp3171G171VgGtgTt11AY.990.001049
ORF1ab/nsp3171G171VgGtgTt11AY.99.10.001553
ORF1ab/nsp3171G171VgGtgTt11B.1.1.1210.002427
ORF1ab/nsp3171G171VgGtgTt11B.1.1.1890.001513
ORF1ab/nsp3171G171VgGtgTt11B.1.1.2160.00089
ORF1ab/nsp3171G171VgGtgTt11B.1.1.2910.000742
ORF1ab/nsp3171G171VgGtgTt11B.1.1.2940.001266
ORF1ab/nsp3171G171VgGtgTt11B.1.1.3060.000438
ORF1ab/nsp3171G171VgGtgTt11B.1.1.3160.000925
ORF1ab/nsp3171G171VgGtgTt11B.1.1.3180.000302
ORF1ab/nsp3171G171VgGtgTt11B.1.1.5180.006329
ORF1ab/nsp3171G171VgGtgTt11B.1.1570.002985
ORF1ab/nsp3171G171VgGtgTt11B.1.177.500.004695
ORF1ab/nsp3171G171VgGtgTt11B.1.177.530.002392
ORF1ab/nsp3171G171VgGtgTt11B.1.177.750.001041
ORF1ab/nsp3171G171VgGtgTt11B.1.258.170.000104
ORF1ab/nsp3171G171VgGtgTt11B.1.2600.003344
ORF1ab/nsp3171G171VgGtgTt11B.1.3050.002151
ORF1ab/nsp3171G171VgGtgTt11B.1.3110.000275
ORF1ab/nsp3171G171VgGtgTt11B.1.3360.002439
ORF1ab/nsp3171G171VgGtgTt11B.1.3500.002933
ORF1ab/nsp3171G171VgGtgTt11B.1.36.170.000494
ORF1ab/nsp3171G171VgGtgTt11B.1.36.220.001208
ORF1ab/nsp3171G171VgGtgTt11B.1.36.290.000517
ORF1ab/nsp3171G171VgGtgTt11B.1.36.80.001
ORF1ab/nsp3171G171VgGtgTt11B.1.3700.008
ORF1ab/nsp3171G171VgGtgTt11B.1.4290.000024
ORF1ab/nsp3171G171VgGtgTt11B.1.4360.001029
ORF1ab/nsp3171G171VgGtgTt11B.1.466.20.000391
ORF1ab/nsp3171G171VgGtgTt11B.1.5090.000866
ORF1ab/nsp3171G171VgGtgTt11B.1.5640.000426
ORF1ab/nsp3171G171VgGtgTt11B.1.6090.000479
ORF1ab/nsp3171G171VgGtgTt11B.1.6290.013333
ORF1ab/nsp3171G171VgGtgTt11B.1.9.50.005682
ORF1ab/nsp3171G171VgGtgTt11B.60.00091
ORF1ab/nsp3171G171VgGtgTt11C.160.00106
ORF1ab/nsp3171G171VgGtgTt11P.1.120.000484
ORF1ab/nsp3171G171VgGtgTt11P.1.170.000162
ORF1ab/nsp3171G171VgGtgTt11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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