CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = F1516V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31516F1516VF2334VnonsynTtcGtc1090.97265-7267
ORF1ab/nsp31516F1516VF2334VnonsynTtCGtT1010.17265-7267

Details of the mutation F1516V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31516F1516VTtcGtc910All0.000002
ORF1ab/nsp31516F1516VTtCGtT110All0
ORF1ab/nsp31516F1516VTtcGtc120.055556
ORF1ab/nsp31516F1516VTtCGtT120.055556
ORF1ab/nsp31516F1516VTtcGtc11AY.260.000028
ORF1ab/nsp31516F1516VTtcGtc11AY.290.000016
ORF1ab/nsp31516F1516VTtcGtc11AY.39.10.00004
ORF1ab/nsp31516F1516VTtcGtc11AY.40.000002
ORF1ab/nsp31516F1516VTtcGtc11AY.46.60.000072
ORF1ab/nsp31516F1516VTtcGtc11B.1.1.70.000001
ORF1ab/nsp31516F1516VTtcGtc11B.1.3510.00003
ORF1ab/nsp31516F1516VTtcGtc11B.1.466.20.000391

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.