CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = F1503L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31503F1503LF2321LnonsynttTttA128570.4453127226-7228
ORF1ab/nsp31503F1503LF2321LnonsynTttCtt128570.4453127226-7228
ORF1ab/nsp31503F1503LF2321LnonsynttTttG128130.1015627226-7228
ORF1ab/nsp31503F1503LF2321LnonsynTtTCtC12810.00781257226-7228

Details of the mutation F1503L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31503F1503LttTttA57128All0.000011
ORF1ab/nsp31503F1503LTttCtt57128All0.000011
ORF1ab/nsp31503F1503LttTttG13128All0.000002
ORF1ab/nsp31503F1503LTtTCtC1128All0
ORF1ab/nsp31503F1503LttTttA1327B.1.1.70.000012
ORF1ab/nsp31503F1503LTttCtt927B.1.1.70.000008
ORF1ab/nsp31503F1503LttTttG427B.1.1.70.000004
ORF1ab/nsp31503F1503LTtTCtC127B.1.1.70.000001
ORF1ab/nsp31503F1503LTttCtt1717B.1.3510.000505
ORF1ab/nsp31503F1503LttTttA1214B.10.00011
ORF1ab/nsp31503F1503LttTttG114B.10.000009
ORF1ab/nsp31503F1503LTttCtt114B.10.000009
ORF1ab/nsp31503F1503LTttCtt99B.1.3180.346154
ORF1ab/nsp31503F1503LTttCtt34AY.40.000005
ORF1ab/nsp31503F1503LttTttA14AY.40.000002
ORF1ab/nsp31503F1503LttTttA24B.1.10.000036
ORF1ab/nsp31503F1503LttTttG14B.1.10.000018
ORF1ab/nsp31503F1503LTttCtt14B.1.10.000018
ORF1ab/nsp31503F1503LttTttA44B.1.1.3480.003185
ORF1ab/nsp31503F1503LttTttA33B.1.1110.003525
ORF1ab/nsp31503F1503LttTttA23B.1.20.000018
ORF1ab/nsp31503F1503LttTttG13B.1.20.000009
ORF1ab/nsp31503F1503LTttCtt23B.1.617.20.000008
ORF1ab/nsp31503F1503LttTttA13B.1.617.20.000004
ORF1ab/nsp31503F1503LttTttA33P.10.000047
ORF1ab/nsp31503F1503LttTttA22AY.1030.000012
ORF1ab/nsp31503F1503LttTttG12AY.30.00001
ORF1ab/nsp31503F1503LttTttA12AY.30.00001
ORF1ab/nsp31503F1503LTttCtt22AY.50.000041
ORF1ab/nsp31503F1503LttTttA12B.1.1770.000013
ORF1ab/nsp31503F1503LTttCtt12B.1.1770.000013
ORF1ab/nsp31503F1503LTttCtt22B.1.2210.000142
ORF1ab/nsp31503F1503LTttCtt12B.1.4290.000024
ORF1ab/nsp31503F1503LttTttG12B.1.4290.000024
ORF1ab/nsp31503F1503LTttCtt22B.1.466.20.000782
ORF1ab/nsp31503F1503LTttCtt22B.1.5610.000794
ORF1ab/nsp31503F1503LttTttA22C.370.000232
ORF1ab/nsp31503F1503LttTttA22P.1.150.000465
ORF1ab/nsp31503F1503LttTttG11A0.000387
ORF1ab/nsp31503F1503LttTttA11AY.1080.001103
ORF1ab/nsp31503F1503LTttCtt11AY.1190.000035
ORF1ab/nsp31503F1503LttTttA11AY.250.000006
ORF1ab/nsp31503F1503LttTttA11AY.260.000028
ORF1ab/nsp31503F1503LTttCtt11AY.4.40.000409
ORF1ab/nsp31503F1503LTttCtt11AY.430.000004
ORF1ab/nsp31503F1503LttTttA11AY.440.000006
ORF1ab/nsp31503F1503LttTttA11AY.450.000122
ORF1ab/nsp31503F1503LttTttA11AY.470.000031
ORF1ab/nsp31503F1503LttTttA11AY.700.000209
ORF1ab/nsp31503F1503LTttCtt11B.1.1.1570.000913
ORF1ab/nsp31503F1503LttTttG11B.1.1.1760.000439
ORF1ab/nsp31503F1503LttTttG11B.1.160.70.002079
ORF1ab/nsp31503F1503LTttCtt11B.1.177.510.004566
ORF1ab/nsp31503F1503LttTttG11B.1.4270.00005
ORF1ab/nsp31503F1503LttTttA11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.