CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = E95D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp395E95DE913DnonsyngaGgaT16922169010.9987593002-3004
ORF1ab/nsp395E95DE913DnonsyngaGgaC16922210.001240993002-3004

Details of the mutation E95D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp395E95DgaGgaT1690116922All0.003233
ORF1ab/nsp395E95DgaGgaC2116922All0.000004
ORF1ab/nsp395E95DgaGgaT1258812588B.1.1.70.011269
ORF1ab/nsp395E95DgaGgaT11991201AY.40.001866
ORF1ab/nsp395E95DgaGgaC21201AY.40.000003
ORF1ab/nsp395E95DgaGgaT579579C.301
ORF1ab/nsp395E95DgaGgaT288288B.1.10.005225
ORF1ab/nsp395E95DgaGgaT283283Q.80.046669
ORF1ab/nsp395E95DgaGgaT256256AY.250.00154
ORF1ab/nsp395E95DgaGgaT155156D.20.011631
ORF1ab/nsp395E95DgaGgaC1156D.20.000075
ORF1ab/nsp395E95DgaGgaT149149C.30.11
ORF1ab/nsp395E95DgaGgaT118118B.1.617.20.000444
ORF1ab/nsp395E95DgaGgaT9396B.1.20.000819
ORF1ab/nsp395E95DgaGgaC396B.1.20.000026
ORF1ab/nsp395E95DgaGgaT8787AY.9.10.007284
ORF1ab/nsp395E95DgaGgaT8181AY.440.000493
ORF1ab/nsp395E95DgaGgaT7777B.1.1770.001014
ORF1ab/nsp395E95DgaGgaT7676AY.1030.000472
ORF1ab/nsp395E95DgaGgaT5353B.10.000485
ORF1ab/nsp395E95DgaGgaT4747AY.700.0098
ORF1ab/nsp395E95DgaGgaT3636AY.430.000159
ORF1ab/nsp395E95DgaGgaT3535AY.840.015311
ORF1ab/nsp395E95DgaGgaT3232AY.30.000318
ORF1ab/nsp395E95DgaGgaT2828P.20.005226
ORF1ab/nsp395E95DgaGgaT2626AY.410.007643
ORF1ab/nsp395E95DgaGgaT2323P.10.000362
ORF1ab/nsp395E95DgaGgaT2020B.1.177.810.003786
ORF1ab/nsp395E95DgaGgaT1818AY.290.000284
ORF1ab/nsp395E95DgaGgaT1818AY.980.001422
ORF1ab/nsp395E95DgaGgaT1818B.1.1.4200.018109
ORF1ab/nsp395E95DgaGgaT1717B.1.3510.000505
ORF1ab/nsp395E95DgaGgaT1515AY.540.00143
ORF1ab/nsp395E95DgaGgaT1515B.1.1.500.010183
ORF1ab/nsp395E95DgaGgaT1414AY.1020.000371
ORF1ab/nsp395E95DgaGgaT1414B.1.360.002043
ORF1ab/nsp395E95DgaGgaT1313AY.680.003559
ORF1ab/nsp395E95DgaGgaT1212AY.470.000373
ORF1ab/nsp395E95DgaGgaT1212B.1.438.10.001287
ORF1ab/nsp395E95DgaGgaT1212B.1.5490.086331
ORF1ab/nsp395E95DgaGgaT1111A.2.5.30.113402
ORF1ab/nsp395E95DgaGgaT1111AY.70.002156
ORF1ab/nsp395E95DgaGgaT1111B.1.4700.015449
ORF1ab/nsp395E95DgaGgaT1111B.1.5260.000259
ORF1ab/nsp395E95DgaGgaT1010B.1.258.50.087719
ORF1ab/nsp395E95DgaGgaT99AY.116.10.002803
ORF1ab/nsp395E95DgaGgaT89AY.390.000198
ORF1ab/nsp395E95DgaGgaC19AY.390.000025
ORF1ab/nsp395E95DgaGgaC48AY.4.20.000087
ORF1ab/nsp395E95DgaGgaT48AY.4.20.000087
ORF1ab/nsp395E95DgaGgaT88B.1.1.2260.046512
ORF1ab/nsp395E95DgaGgaT88B.1.1.3060.003507
ORF1ab/nsp395E95DgaGgaT88B.1.177.50.009938
ORF1ab/nsp395E95DgaGgaT88B.1.2580.000532
ORF1ab/nsp395E95DgaGgaT88Q.10.001011
ORF1ab/nsp395E95DgaGgaT77AY.610.000733
ORF1ab/nsp395E95DgaGgaT77B.1.1.2250.05036
ORF1ab/nsp395E95DgaGgaT77B.1.1.5190.000278
ORF1ab/nsp395E95DgaGgaT77B.1.4270.000353
ORF1ab/nsp395E95DgaGgaC77B.1.6370.000512
ORF1ab/nsp395E95DgaGgaT66AY.1210.000812
ORF1ab/nsp395E95DgaGgaT66AY.9.20.00022
ORF1ab/nsp395E95DgaGgaT66AY.98.10.000291
ORF1ab/nsp395E95DgaGgaT66B.1.1600.000187
ORF1ab/nsp395E95DgaGgaT66B.1.177.40.001266
ORF1ab/nsp395E95DgaGgaT55AY.230.000349
ORF1ab/nsp395E95DgaGgaT55B.1.177.440.002595
ORF1ab/nsp395E95DgaGgaT55B.1.2910.096154
ORF1ab/nsp395E95DgaGgaT44AY.1180.000251
ORF1ab/nsp395E95DgaGgaT44AY.200.000155
ORF1ab/nsp395E95DgaGgaT44AY.260.000113
ORF1ab/nsp395E95DgaGgaT44AY.50.000083
ORF1ab/nsp395E95DgaGgaT44AY.750.000224
ORF1ab/nsp395E95DgaGgaT44B.1.1.2220.000816
ORF1ab/nsp395E95DgaGgaT44B.1.1.4850.066667
ORF1ab/nsp395E95DgaGgaT44B.1.177.510.018265
ORF1ab/nsp395E95DgaGgaT44B.1.6210.000354
ORF1ab/nsp395E95DgaGgaT33A.2.50.001497
ORF1ab/nsp395E95DgaGgaT33AY.300.001187
ORF1ab/nsp395E95DgaGgaT33AY.320.001597
ORF1ab/nsp395E95DgaGgaT33AY.450.000365
ORF1ab/nsp395E95DgaGgaT33AY.5.30.001012
ORF1ab/nsp395E95DgaGgaT33AY.90.000203
ORF1ab/nsp395E95DgaGgaT33B.1.1.1330.025424
ORF1ab/nsp395E95DgaGgaT33B.1.177.60.00293
ORF1ab/nsp395E95DgaGgaT33B.1.177.70.000495
ORF1ab/nsp395E95DgaGgaT33B.1.177.720.010169
ORF1ab/nsp395E95DgaGgaT33B.1.258.170.000312
ORF1ab/nsp395E95DgaGgaT33B.1.3110.000824
ORF1ab/nsp395E95DgaGgaT33B.1.5960.000261
ORF1ab/nsp395E95DgaGgaT33B.1.617.10.000387
ORF1ab/nsp395E95DgaGgaT33C.180.007772
ORF1ab/nsp395E95DgaGgaT33C.370.000348
ORF1ab/nsp395E95DgaGgaT33P.1.170.000485
ORF1ab/nsp395E95DgaGgaT33P.1.70.000958
ORF1ab/nsp395E95DgaGgaT22AY.1000.000092
ORF1ab/nsp395E95DgaGgaT22AY.1040.003968
ORF1ab/nsp395E95DgaGgaT22AY.1140.000462
ORF1ab/nsp395E95DgaGgaT22AY.1160.000574
ORF1ab/nsp395E95DgaGgaT22AY.130.000322
ORF1ab/nsp395E95DgaGgaT22AY.160.000759
ORF1ab/nsp395E95DgaGgaT22AY.270.000129
ORF1ab/nsp395E95DgaGgaT22AY.340.000194
ORF1ab/nsp395E95DgaGgaT22AY.580.001815
ORF1ab/nsp395E95DgaGgaT22B.1.1.100.00223
ORF1ab/nsp395E95DgaGgaT22B.1.1.1740.006757
ORF1ab/nsp395E95DgaGgaT22B.1.1.2140.000111
ORF1ab/nsp395E95DgaGgaT22B.1.1.2200.003717
ORF1ab/nsp395E95DgaGgaT22B.1.1390.001466
ORF1ab/nsp395E95DgaGgaT22B.1.2210.000142
ORF1ab/nsp395E95DgaGgaT22B.1.36.70.008
ORF1ab/nsp395E95DgaGgaT22B.1.4340.105263
ORF1ab/nsp395E95DgaGgaT22B.4.50.02381
ORF1ab/nsp395E95DgaGgaT22P.1.140.000096
ORF1ab/nsp395E95DgaGgaT22Q.60.013245
ORF1ab/nsp395E95DgaGgaT22R.10.00018
ORF1ab/nsp395E95DgaGgaT11A.20.000662
ORF1ab/nsp395E95DgaGgaT11AY.1130.000142
ORF1ab/nsp395E95DgaGgaT11AY.1190.000035
ORF1ab/nsp395E95DgaGgaT11AY.1200.000037
ORF1ab/nsp395E95DgaGgaT11AY.140.000088
ORF1ab/nsp395E95DgaGgaT11AY.16.10.00047
ORF1ab/nsp395E95DgaGgaT11AY.370.000316
ORF1ab/nsp395E95DgaGgaT11AY.4.30.000842
ORF1ab/nsp395E95DgaGgaT11AY.400.000964
ORF1ab/nsp395E95DgaGgaT11AY.420.00004
ORF1ab/nsp395E95DgaGgaT11AY.460.000104
ORF1ab/nsp395E95DgaGgaT11AY.5.40.000277
ORF1ab/nsp395E95DgaGgaT11AY.510.000909
ORF1ab/nsp395E95DgaGgaT11AY.550.000917
ORF1ab/nsp395E95DgaGgaT11AY.560.001605
ORF1ab/nsp395E95DgaGgaT11AY.600.000938
ORF1ab/nsp395E95DgaGgaT11AY.670.000464
ORF1ab/nsp395E95DgaGgaC11AY.80.000606
ORF1ab/nsp395E95DgaGgaT11AY.920.000287
ORF1ab/nsp395E95DgaGgaT11AY.990.001049
ORF1ab/nsp395E95DgaGgaT11B0.000128
ORF1ab/nsp395E95DgaGgaT11B.1.1.1600.02381
ORF1ab/nsp395E95DgaGgaT11B.1.1.1700.001247
ORF1ab/nsp395E95DgaGgaT11B.1.1.1710.003676
ORF1ab/nsp395E95DgaGgaT11B.1.1.1940.00495
ORF1ab/nsp395E95DgaGgaT11B.1.1.2160.00089
ORF1ab/nsp395E95DgaGgaT11B.1.1.2300.009174
ORF1ab/nsp395E95DgaGgaT11B.1.1.250.000569
ORF1ab/nsp395E95DgaGgaT11B.1.1.2630.001558
ORF1ab/nsp395E95DgaGgaT11B.1.1.2770.000759
ORF1ab/nsp395E95DgaGgaT11B.1.1.2790.001121
ORF1ab/nsp395E95DgaGgaT11B.1.1.280.000311
ORF1ab/nsp395E95DgaGgaT11B.1.1.3040.002809
ORF1ab/nsp395E95DgaGgaT11B.1.1.3120.001912
ORF1ab/nsp395E95DgaGgaT11B.1.1.3170.000412
ORF1ab/nsp395E95DgaGgaT11B.1.1.3180.000302
ORF1ab/nsp395E95DgaGgaT11B.1.1.3720.000689
ORF1ab/nsp395E95DgaGgaT11B.1.1.3740.002375
ORF1ab/nsp395E95DgaGgaT11B.1.1.390.00051
ORF1ab/nsp395E95DgaGgaT11B.1.1.4330.001425
ORF1ab/nsp395E95DgaGgaT11B.1.1.440.00241
ORF1ab/nsp395E95DgaGgaT11B.1.1.4640.001473
ORF1ab/nsp395E95DgaGgaT11B.1.1.480.002874
ORF1ab/nsp395E95DgaGgaT11B.1.1.520.012195
ORF1ab/nsp395E95DgaGgaT11B.1.1.5280.004808
ORF1ab/nsp395E95DgaGgaT11B.1.1.580.005376
ORF1ab/nsp395E95DgaGgaC11B.1.1.700.000341
ORF1ab/nsp395E95DgaGgaT11B.1.1.710.006061
ORF1ab/nsp395E95DgaGgaT11B.1.177.120.000152
ORF1ab/nsp395E95DgaGgaT11B.1.2140.003663
ORF1ab/nsp395E95DgaGgaT11B.1.2430.00007
ORF1ab/nsp395E95DgaGgaT11B.1.2600.003344
ORF1ab/nsp395E95DgaGgaT11B.1.2790.000514
ORF1ab/nsp395E95DgaGgaC11B.1.36.290.000517
ORF1ab/nsp395E95DgaGgaT11B.1.3780.006849
ORF1ab/nsp395E95DgaGgaT11B.1.4020.009804
ORF1ab/nsp395E95DgaGgaT11B.1.4090.000781
ORF1ab/nsp395E95DgaGgaT11B.1.4250.002994
ORF1ab/nsp395E95DgaGgaT11B.1.4690.00361
ORF1ab/nsp395E95DgaGgaT11B.1.4990.00105
ORF1ab/nsp395E95DgaGgaT11B.1.5240.001406
ORF1ab/nsp395E95DgaGgaT11B.1.5250.000113
ORF1ab/nsp395E95DgaGgaT11B.1.5510.00129
ORF1ab/nsp395E95DgaGgaT11B.1.5760.000907
ORF1ab/nsp395E95DgaGgaT11B.1.5970.00463
ORF1ab/nsp395E95DgaGgaT11B.1.6190.000871
ORF1ab/nsp395E95DgaGgaT11B.1.6200.000946
ORF1ab/nsp395E95DgaGgaT11B.1.621.10.000506
ORF1ab/nsp395E95DgaGgaT11B.350.007812
ORF1ab/nsp395E95DgaGgaT11B.6.10.026316
ORF1ab/nsp395E95DgaGgaT11C.360.000911
ORF1ab/nsp395E95DgaGgaT11C.36.30.000567
ORF1ab/nsp395E95DgaGgaT11D.30.005917
ORF1ab/nsp395E95DgaGgaT11P.1.160.000374
ORF1ab/nsp395E95DgaGgaT11P.1.60.001946
ORF1ab/nsp395E95DgaGgaT11P.50.013699
ORF1ab/nsp395E95DgaGgaT11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.