CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = E378L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3378E378LE1196LnonsynGAaTTa43390.9069773851-3853
ORF1ab/nsp3378E378LE1196LnonsynGAATTG4320.04651163851-3853
ORF1ab/nsp3378E378LE1196LnonsynGAaCTa4310.02325583851-3853
ORF1ab/nsp3378E378LE1196LnonsynGAACTG4310.02325583851-3853

Details of the mutation E378L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3378E378LGAaTTa3943All0.000007
ORF1ab/nsp3378E378LGAATTG243All0
ORF1ab/nsp3378E378LGAaCTa143All0
ORF1ab/nsp3378E378LGAACTG143All0
ORF1ab/nsp3378E378LGAaTTa3640B.1.1.70.000032
ORF1ab/nsp3378E378LGAATTG240B.1.1.70.000002
ORF1ab/nsp3378E378LGAACTG140B.1.1.70.000001
ORF1ab/nsp3378E378LGAaCTa140B.1.1.70.000001
ORF1ab/nsp3378E378LGAaTTa11AY.250.000006
ORF1ab/nsp3378E378LGAaTTa11B.1.5760.000907
ORF1ab/nsp3378E378LGAaTTa11P.10.000016