CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = D729Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3729D729YD1547YnonsynGatTat2815281514904-4906

Details of the mutation D729Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3729D729YGatTat28152815All0.000538
ORF1ab/nsp3729D729YGatTat686686B.1.1.70.000614
ORF1ab/nsp3729D729YGatTat429429AY.430.001901
ORF1ab/nsp3729D729YGatTat239239AY.30.002377
ORF1ab/nsp3729D729YGatTat143143AY.40.000223
ORF1ab/nsp3729D729YGatTat123123B.1.617.20.000463
ORF1ab/nsp3729D729YGatTat7171AY.1030.000441
ORF1ab/nsp3729D729YGatTat6666B.1.5521
ORF1ab/nsp3729D729YGatTat6363P.10.000993
ORF1ab/nsp3729D729YGatTat5959AY.440.000359
ORF1ab/nsp3729D729YGatTat4949AY.270.003171
ORF1ab/nsp3729D729YGatTat4747B.1.160.160.04368
ORF1ab/nsp3729D729YGatTat4646AY.1020.00122
ORF1ab/nsp3729D729YGatTat4242AY.690.00784
ORF1ab/nsp3729D729YGatTat4242B.1.20.00037
ORF1ab/nsp3729D729YGatTat3333B.10.000302
ORF1ab/nsp3729D729YGatTat2929AY.250.000174
ORF1ab/nsp3729D729YGatTat2929B.1.4780.341176
ORF1ab/nsp3729D729YGatTat2626AY.46.60.001877
ORF1ab/nsp3729D729YGatTat2525AY.260.000708
ORF1ab/nsp3729D729YGatTat2323AY.390.000568
ORF1ab/nsp3729D729YGatTat2323B.1.177.320.031039
ORF1ab/nsp3729D729YGatTat2121B.1.10.000381
ORF1ab/nsp3729D729YGatTat2020AY.1000.00092
ORF1ab/nsp3729D729YGatTat1919AY.1200.000706
ORF1ab/nsp3729D729YGatTat1818AY.330.001202
ORF1ab/nsp3729D729YGatTat1616B.1.3510.000476
ORF1ab/nsp3729D729YGatTat1313AY.3.10.001108
ORF1ab/nsp3729D729YGatTat1313B.1.2580.000865
ORF1ab/nsp3729D729YGatTat1212B.1.110.30.008621
ORF1ab/nsp3729D729YGatTat1212B.1.5960.001046
ORF1ab/nsp3729D729YGatTat1111AY.620.004793
ORF1ab/nsp3729D729YGatTat1111B.1.4290.000259
ORF1ab/nsp3729D729YGatTat1010B.1.177.810.001893
ORF1ab/nsp3729D729YGatTat1010B.1.6370.000731
ORF1ab/nsp3729D729YGatTat1010P.1.140.000478
ORF1ab/nsp3729D729YGatTat99AY.1210.001218
ORF1ab/nsp3729D729YGatTat99AY.200.00035
ORF1ab/nsp3729D729YGatTat99AY.470.00028
ORF1ab/nsp3729D729YGatTat99AY.9.20.000331
ORF1ab/nsp3729D729YGatTat88B.1.177.120.001214
ORF1ab/nsp3729D729YGatTat88B.1.177.540.004851
ORF1ab/nsp3729D729YGatTat77AY.340.000679
ORF1ab/nsp3729D729YGatTat77AY.98.10.000339
ORF1ab/nsp3729D729YGatTat77D.20.000525
ORF1ab/nsp3729D729YGatTat66AY.1110.001099
ORF1ab/nsp3729D729YGatTat66AZ.20.004926
ORF1ab/nsp3729D729YGatTat66B.1.160.140.012712
ORF1ab/nsp3729D729YGatTat66B.1.1770.000079
ORF1ab/nsp3729D729YGatTat55AY.1180.000313
ORF1ab/nsp3729D729YGatTat55AY.4.20.000108
ORF1ab/nsp3729D729YGatTat55AY.610.000524
ORF1ab/nsp3729D729YGatTat55B.1.1.3170.002058
ORF1ab/nsp3729D729YGatTat55B.1.3560.008636
ORF1ab/nsp3729D729YGatTat55B.1.5260.000118
ORF1ab/nsp3729D729YGatTat44AY.1130.00057
ORF1ab/nsp3729D729YGatTat44AY.420.000161
ORF1ab/nsp3729D729YGatTat44AY.450.000487
ORF1ab/nsp3729D729YGatTat44AY.9.10.000335
ORF1ab/nsp3729D729YGatTat44B.1.1.2140.000222
ORF1ab/nsp3729D729YGatTat44B.1.1600.000125
ORF1ab/nsp3729D729YGatTat44B.1.258.170.000416
ORF1ab/nsp3729D729YGatTat33AY.1190.000106
ORF1ab/nsp3729D729YGatTat33AY.460.000312
ORF1ab/nsp3729D729YGatTat33AY.50.000062
ORF1ab/nsp3729D729YGatTat33AY.80.001818
ORF1ab/nsp3729D729YGatTat33AY.99.20.000276
ORF1ab/nsp3729D729YGatTat33B.1.1.2160.002671
ORF1ab/nsp3729D729YGatTat33B.1.1.3020.006224
ORF1ab/nsp3729D729YGatTat33B.1.2210.000213
ORF1ab/nsp3729D729YGatTat33B.1.258.30.005025
ORF1ab/nsp3729D729YGatTat33B.1.3910.003382
ORF1ab/nsp3729D729YGatTat33B.1.4270.000151
ORF1ab/nsp3729D729YGatTat33N.50.0053
ORF1ab/nsp3729D729YGatTat33P.1.70.000958
ORF1ab/nsp3729D729YGatTat33Q.10.000379
ORF1ab/nsp3729D729YGatTat22A.23.10.001408
ORF1ab/nsp3729D729YGatTat22AY.10.000791
ORF1ab/nsp3729D729YGatTat22AY.290.000032
ORF1ab/nsp3729D729YGatTat22AY.39.1.10.001449
ORF1ab/nsp3729D729YGatTat22AY.4.50.000215
ORF1ab/nsp3729D729YGatTat22AY.60.000082
ORF1ab/nsp3729D729YGatTat22AY.750.000112
ORF1ab/nsp3729D729YGatTat22AY.75.10.000361
ORF1ab/nsp3729D729YGatTat22AY.790.002421
ORF1ab/nsp3729D729YGatTat22AY.930.000546
ORF1ab/nsp3729D729YGatTat22AY.980.000158
ORF1ab/nsp3729D729YGatTat22B.1.1.1890.003026
ORF1ab/nsp3729D729YGatTat22B.1.1.2220.000408
ORF1ab/nsp3729D729YGatTat22B.1.1.2690.002706
ORF1ab/nsp3729D729YGatTat22B.1.1.280.000622
ORF1ab/nsp3729D729YGatTat22B.1.1.3060.000877
ORF1ab/nsp3729D729YGatTat22B.1.1.330.000842
ORF1ab/nsp3729D729YGatTat22B.1.1.500.001358
ORF1ab/nsp3729D729YGatTat22B.1.1.5170.013605
ORF1ab/nsp3729D729YGatTat22B.1.1.5190.000079
ORF1ab/nsp3729D729YGatTat22B.1.160.250.022222
ORF1ab/nsp3729D729YGatTat22B.1.177.600.000437
ORF1ab/nsp3729D729YGatTat22B.1.1890.008584
ORF1ab/nsp3729D729YGatTat22B.1.2430.000139
ORF1ab/nsp3729D729YGatTat22B.1.360.000292
ORF1ab/nsp3729D729YGatTat22B.1.6190.001742
ORF1ab/nsp3729D729YGatTat22B.1.930.001867
ORF1ab/nsp3729D729YGatTat22B.400.000729
ORF1ab/nsp3729D729YGatTat22C.360.001821
ORF1ab/nsp3729D729YGatTat22P.20.000373
ORF1ab/nsp3729D729YGatTat11A.2.50.000499
ORF1ab/nsp3729D729YGatTat11A.270.001656
ORF1ab/nsp3729D729YGatTat11AP.10.001502
ORF1ab/nsp3729D729YGatTat11AT.10.005128
ORF1ab/nsp3729D729YGatTat11AY.1040.001984
ORF1ab/nsp3729D729YGatTat11AY.1070.000466
ORF1ab/nsp3729D729YGatTat11AY.1140.000231
ORF1ab/nsp3729D729YGatTat11AY.1170.000085
ORF1ab/nsp3729D729YGatTat11AY.140.000088
ORF1ab/nsp3729D729YGatTat11AY.150.002222
ORF1ab/nsp3729D729YGatTat11AY.190.00114
ORF1ab/nsp3729D729YGatTat11AY.230.00007
ORF1ab/nsp3729D729YGatTat11AY.29.10.000221
ORF1ab/nsp3729D729YGatTat11AY.360.000148
ORF1ab/nsp3729D729YGatTat11AY.4.2.10.000149
ORF1ab/nsp3729D729YGatTat11AY.46.20.000635
ORF1ab/nsp3729D729YGatTat11AY.480.000465
ORF1ab/nsp3729D729YGatTat11AY.530.000288
ORF1ab/nsp3729D729YGatTat11AY.580.000907
ORF1ab/nsp3729D729YGatTat11AY.630.000387
ORF1ab/nsp3729D729YGatTat11AY.680.000274
ORF1ab/nsp3729D729YGatTat11AY.830.001724
ORF1ab/nsp3729D729YGatTat11AY.880.000884
ORF1ab/nsp3729D729YGatTat11B0.000128
ORF1ab/nsp3729D729YGatTat11B.1.1.1340.011364
ORF1ab/nsp3729D729YGatTat11B.1.1.1610.003534
ORF1ab/nsp3729D729YGatTat11B.1.1.2510.007937
ORF1ab/nsp3729D729YGatTat11B.1.1.2790.001121
ORF1ab/nsp3729D729YGatTat11B.1.1.2820.011628
ORF1ab/nsp3729D729YGatTat11B.1.1.2840.000107
ORF1ab/nsp3729D729YGatTat11B.1.1.2860.002899
ORF1ab/nsp3729D729YGatTat11B.1.1.3160.000925
ORF1ab/nsp3729D729YGatTat11B.1.1.3260.001761
ORF1ab/nsp3729D729YGatTat11B.1.1.3970.002252
ORF1ab/nsp3729D729YGatTat11B.1.1.4480.002033
ORF1ab/nsp3729D729YGatTat11B.1.1.4660.008696
ORF1ab/nsp3729D729YGatTat11B.1.1470.000756
ORF1ab/nsp3729D729YGatTat11B.1.160.230.004831
ORF1ab/nsp3729D729YGatTat11B.1.177.160.000664
ORF1ab/nsp3729D729YGatTat11B.1.177.210.000076
ORF1ab/nsp3729D729YGatTat11B.1.177.860.000183
ORF1ab/nsp3729D729YGatTat11B.1.1990.004132
ORF1ab/nsp3729D729YGatTat11B.1.2100.002132
ORF1ab/nsp3729D729YGatTat11B.1.2340.000132
ORF1ab/nsp3729D729YGatTat11B.1.2360.002053
ORF1ab/nsp3729D729YGatTat11B.1.2410.000812
ORF1ab/nsp3729D729YGatTat11B.1.258.110.000396
ORF1ab/nsp3729D729YGatTat11B.1.2790.000514
ORF1ab/nsp3729D729YGatTat11B.1.3290.000608
ORF1ab/nsp3729D729YGatTat11B.1.36.170.000494
ORF1ab/nsp3729D729YGatTat11B.1.3670.000792
ORF1ab/nsp3729D729YGatTat11B.1.3710.001122
ORF1ab/nsp3729D729YGatTat11B.1.3810.007812
ORF1ab/nsp3729D729YGatTat11B.1.3990.001934
ORF1ab/nsp3729D729YGatTat11B.1.4410.009615
ORF1ab/nsp3729D729YGatTat11B.1.4480.002625
ORF1ab/nsp3729D729YGatTat11B.1.4590.004082
ORF1ab/nsp3729D729YGatTat11B.1.466.20.000391
ORF1ab/nsp3729D729YGatTat11B.1.5650.00081
ORF1ab/nsp3729D729YGatTat11B.1.5950.000261
ORF1ab/nsp3729D729YGatTat11B.1.617.10.000129
ORF1ab/nsp3729D729YGatTat11B.1.6210.000089
ORF1ab/nsp3729D729YGatTat11B.1.6220.012987
ORF1ab/nsp3729D729YGatTat11B.3.10.001658
ORF1ab/nsp3729D729YGatTat11B.610.005747
ORF1ab/nsp3729D729YGatTat11C.36.30.000567
ORF1ab/nsp3729D729YGatTat11C.370.000116
ORF1ab/nsp3729D729YGatTat11P.1.170.000162
ORF1ab/nsp3729D729YGatTat11P.1.20.001156

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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