CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = D455N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3455D455ND1273NnonsynGacAac1221210.9918034082-4084
ORF1ab/nsp3455D455ND1273NnonsynGaCAaT12210.008196724082-4084

Details of the mutation D455N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3455D455NGacAac121122All0.000023
ORF1ab/nsp3455D455NGaCAaT1122All0
ORF1ab/nsp3455D455NGacAac2929B.1.1.70.000026
ORF1ab/nsp3455D455NGacAac1212B.1.10.000218
ORF1ab/nsp3455D455NGacAac1010AY.390.000247
ORF1ab/nsp3455D455NGacAac1010B.1.20.000088
ORF1ab/nsp3455D455NGacAac77B.1.1.3050.027027
ORF1ab/nsp3455D455NGacAac66B.1.617.20.000023
ORF1ab/nsp3455D455NGacAac55AY.1030.000031
ORF1ab/nsp3455D455NGacAac55B.1.5260.000118
ORF1ab/nsp3455D455NGacAac44AY.470.000124
ORF1ab/nsp3455D455NGacAac33AY.430.000013
ORF1ab/nsp3455D455NGacAac33B.10.000027
ORF1ab/nsp3455D455NGacAac33Q.80.000495
ORF1ab/nsp3455D455NGaCAaT120.055556
ORF1ab/nsp3455D455NGacAac120.055556
ORF1ab/nsp3455D455NGacAac22AY.130.000322
ORF1ab/nsp3455D455NGacAac22AY.230.000139
ORF1ab/nsp3455D455NGacAac22AY.30.00002
ORF1ab/nsp3455D455NGacAac22B.1.1.370.000386
ORF1ab/nsp3455D455NGacAac22B.1.177.600.000437
ORF1ab/nsp3455D455NGacAac11AY.290.000016
ORF1ab/nsp3455D455NGacAac11AY.320.000532
ORF1ab/nsp3455D455NGacAac11AY.360.000148
ORF1ab/nsp3455D455NGacAac11AY.40.000002
ORF1ab/nsp3455D455NGacAac11AY.4.20.000022
ORF1ab/nsp3455D455NGacAac11AY.650.000533
ORF1ab/nsp3455D455NGacAac11AY.680.000274
ORF1ab/nsp3455D455NGacAac11AY.9.20.000037
ORF1ab/nsp3455D455NGacAac11B.1.1.2280.003049
ORF1ab/nsp3455D455NGacAac11B.1.2100.002132
ORF1ab/nsp3455D455NGacAac11B.1.5610.000397
ORF1ab/nsp3455D455NGacAac11B.1.6190.000871
ORF1ab/nsp3455D455NGacAac11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.