CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = D339D

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3339D339DD1157DsyngaCgaT4064406413734-3736

Details of the mutation D339D within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3339D339DgaCgaT40644064All0.000777
ORF1ab/nsp3339D339DgaCgaT10201020AY.40.001588
ORF1ab/nsp3339D339DgaCgaT452452B.1.1.70.000405
ORF1ab/nsp3339D339DgaCgaT302302P.60.949686
ORF1ab/nsp3339D339DgaCgaT201201B.1.1.630.077546
ORF1ab/nsp3339D339DgaCgaT159159B.1.2210.011294
ORF1ab/nsp3339D339DgaCgaT132132AY.30.001313
ORF1ab/nsp3339D339DgaCgaT131131B.1.351.20.039637
ORF1ab/nsp3339D339DgaCgaT9292AY.250.000553
ORF1ab/nsp3339D339DgaCgaT8383B.1.20.000731
ORF1ab/nsp3339D339DgaCgaT8383B.1.617.20.000313
ORF1ab/nsp3339D339DgaCgaT7474P.10.001166
ORF1ab/nsp3339D339DgaCgaT6464B.10.000586
ORF1ab/nsp3339D339DgaCgaT6262B.1.2400.013365
ORF1ab/nsp3339D339DgaCgaT6060AY.1030.000373
ORF1ab/nsp3339D339DgaCgaT5959B.1.10.00107
ORF1ab/nsp3339D339DgaCgaT5757AY.390.001409
ORF1ab/nsp3339D339DgaCgaT5454AY.430.000239
ORF1ab/nsp3339D339DgaCgaT5151AY.470.001586
ORF1ab/nsp3339D339DgaCgaT5151B.1.2410.041396
ORF1ab/nsp3339D339DgaCgaT4040B.1.258.170.004159
ORF1ab/nsp3339D339DgaCgaT3636AY.440.000219
ORF1ab/nsp3339D339DgaCgaT3232AY.260.000906
ORF1ab/nsp3339D339DgaCgaT3131B.1.1770.000408
ORF1ab/nsp3339D339DgaCgaT3030B.1.4290.000706
ORF1ab/nsp3339D339DgaCgaT2929B.1.1.4640.04271
ORF1ab/nsp3339D339DgaCgaT2828B.1.1.2840.003007
ORF1ab/nsp3339D339DgaCgaT2727B.1.2580.001797
ORF1ab/nsp3339D339DgaCgaT2727B.1.3710.030303
ORF1ab/nsp3339D339DgaCgaT2525B.1.1600.00078
ORF1ab/nsp3339D339DgaCgaT2323B.1.5260.000541
ORF1ab/nsp3339D339DgaCgaT2121AY.130.003381
ORF1ab/nsp3339D339DgaCgaT1717C.370.001973
ORF1ab/nsp3339D339DgaCgaT1616AY.4.40.006547
ORF1ab/nsp3339D339DgaCgaT1616B.1.1.5190.000635
ORF1ab/nsp3339D339DgaCgaT1414B.1.3510.000416
ORF1ab/nsp3339D339DgaCgaT1313AY.120.10.004173
ORF1ab/nsp3339D339DgaCgaT1111AY.50.000227
ORF1ab/nsp3339D339DgaCgaT1111AY.9.20.000404
ORF1ab/nsp3339D339DgaCgaT1111AY.940.004869
ORF1ab/nsp3339D339DgaCgaT1111B.1.177.770.007988
ORF1ab/nsp3339D339DgaCgaT1010AY.230.000697
ORF1ab/nsp3339D339DgaCgaT1010AY.330.000668
ORF1ab/nsp3339D339DgaCgaT1010AY.610.001048
ORF1ab/nsp3339D339DgaCgaT1010Q.30.00145
ORF1ab/nsp3339D339DgaCgaT99AY.1000.000414
ORF1ab/nsp3339D339DgaCgaT99B.1.1.2440.138462
ORF1ab/nsp3339D339DgaCgaT99B.1.36.170.004447
ORF1ab/nsp3339D339DgaCgaT99B.1.6210.000797
ORF1ab/nsp3339D339DgaCgaT88AY.1020.000212
ORF1ab/nsp3339D339DgaCgaT88AY.290.000126
ORF1ab/nsp3339D339DgaCgaT88B.1.1.2140.000444
ORF1ab/nsp3339D339DgaCgaT88B.1.36.10.009122
ORF1ab/nsp3339D339DgaCgaT88D.20.0006
ORF1ab/nsp3339D339DgaCgaT88R.10.00072
ORF1ab/nsp3339D339DgaCgaT77AY.46.40.001152
ORF1ab/nsp3339D339DgaCgaT66AY.1200.000223
ORF1ab/nsp3339D339DgaCgaT66B.1.1.3060.00263
ORF1ab/nsp3339D339DgaCgaT66B.1.351.50.003597
ORF1ab/nsp3339D339DgaCgaT66B.1.36.290.003104
ORF1ab/nsp3339D339DgaCgaT66P.1.140.000287
ORF1ab/nsp3339D339DgaCgaT55AY.1180.000313
ORF1ab/nsp3339D339DgaCgaT55AY.140.00044
ORF1ab/nsp3339D339DgaCgaT55AY.200.000194
ORF1ab/nsp3339D339DgaCgaT55AY.420.000201
ORF1ab/nsp3339D339DgaCgaT55AY.620.002179
ORF1ab/nsp3339D339DgaCgaT55B.1.1.250.002843
ORF1ab/nsp3339D339DgaCgaT55B.1.1.4340.001743
ORF1ab/nsp3339D339DgaCgaT55B.1.2340.00066
ORF1ab/nsp3339D339DgaCgaT55B.1.6370.000365
ORF1ab/nsp3339D339DgaCgaT44AY.160.001519
ORF1ab/nsp3339D339DgaCgaT44AY.46.60.000289
ORF1ab/nsp3339D339DgaCgaT44AY.90.00027
ORF1ab/nsp3339D339DgaCgaT44B.1.1.1570.003653
ORF1ab/nsp3339D339DgaCgaT44B.1.1.280.001245
ORF1ab/nsp3339D339DgaCgaT44B.1.1.3020.008299
ORF1ab/nsp3339D339DgaCgaT44B.1.1.3170.001647
ORF1ab/nsp3339D339DgaCgaT44B.1.1.4620.034483
ORF1ab/nsp3339D339DgaCgaT44B.1.4000.001716
ORF1ab/nsp3339D339DgaCgaT44B.1.6280.001409
ORF1ab/nsp3339D339DgaCgaT33AY.1170.000254
ORF1ab/nsp3339D339DgaCgaT33AY.1190.000106
ORF1ab/nsp3339D339DgaCgaT33AY.39.10.000119
ORF1ab/nsp3339D339DgaCgaT33AY.46.50.000595
ORF1ab/nsp3339D339DgaCgaT33AY.99.20.000276
ORF1ab/nsp3339D339DgaCgaT33B0.000383
ORF1ab/nsp3339D339DgaCgaT33B.1.1.2220.000612
ORF1ab/nsp3339D339DgaCgaT33B.1.1.2940.003797
ORF1ab/nsp3339D339DgaCgaT33B.1.177.90.003995
ORF1ab/nsp3339D339DgaCgaT33B.1.4270.000151
ORF1ab/nsp3339D339DgaCgaT33B.1.4970.000944
ORF1ab/nsp3339D339DgaCgaT33B.1.5640.001278
ORF1ab/nsp3339D339DgaCgaT22AD.20.000438
ORF1ab/nsp3339D339DgaCgaT22AY.1050.001286
ORF1ab/nsp3339D339DgaCgaT22AY.1070.000932
ORF1ab/nsp3339D339DgaCgaT22AY.450.000243
ORF1ab/nsp3339D339DgaCgaT22AY.630.000774
ORF1ab/nsp3339D339DgaCgaT22AY.690.000373
ORF1ab/nsp3339D339DgaCgaT22AY.740.000231
ORF1ab/nsp3339D339DgaCgaT22AY.910.001461
ORF1ab/nsp3339D339DgaCgaT22AY.980.000158
ORF1ab/nsp3339D339DgaCgaT22B.1.1.330.000842
ORF1ab/nsp3339D339DgaCgaT22B.1.1.4480.004065
ORF1ab/nsp3339D339DgaCgaT22B.1.1.610.017544
ORF1ab/nsp3339D339DgaCgaT22B.1.177.600.000437
ORF1ab/nsp3339D339DgaCgaT22B.1.2430.000139
ORF1ab/nsp3339D339DgaCgaT22B.1.3690.00057
ORF1ab/nsp3339D339DgaCgaT22B.1.4780.023529
ORF1ab/nsp3339D339DgaCgaT22B.1.5960.000174
ORF1ab/nsp3339D339DgaCgaT22B.1.6230.001073
ORF1ab/nsp3339D339DgaCgaT22C.360.001821
ORF1ab/nsp3339D339DgaCgaT22N.60.014184
ORF1ab/nsp3339D339DgaCgaT22P.1.10.000635
ORF1ab/nsp3339D339DgaCgaT22P.1.120.000968
ORF1ab/nsp3339D339DgaCgaT22P.20.000373
ORF1ab/nsp3339D339DgaCgaT22Q.10.000253
ORF1ab/nsp3339D339DgaCgaT110.055556
ORF1ab/nsp3339D339DgaCgaT11A.2.5.10.004808
ORF1ab/nsp3339D339DgaCgaT11AY.1060.000335
ORF1ab/nsp3339D339DgaCgaT11AY.1130.000142
ORF1ab/nsp3339D339DgaCgaT11AY.1210.000135
ORF1ab/nsp3339D339DgaCgaT11AY.23.10.000417
ORF1ab/nsp3339D339DgaCgaT11AY.29.10.000221
ORF1ab/nsp3339D339DgaCgaT11AY.3.10.000085
ORF1ab/nsp3339D339DgaCgaT11AY.4.20.000022
ORF1ab/nsp3339D339DgaCgaT11AY.4.2.10.000149
ORF1ab/nsp3339D339DgaCgaT11AY.4.50.000107
ORF1ab/nsp3339D339DgaCgaT11AY.460.000104
ORF1ab/nsp3339D339DgaCgaT11AY.46.10.001027
ORF1ab/nsp3339D339DgaCgaT11AY.46.20.000635
ORF1ab/nsp3339D339DgaCgaT11AY.46.30.000934
ORF1ab/nsp3339D339DgaCgaT11AY.480.000465
ORF1ab/nsp3339D339DgaCgaT11AY.570.000656
ORF1ab/nsp3339D339DgaCgaT11AY.60.000041
ORF1ab/nsp3339D339DgaCgaT11AY.650.000533
ORF1ab/nsp3339D339DgaCgaT11AY.720.001361
ORF1ab/nsp3339D339DgaCgaT11AY.75.10.00018
ORF1ab/nsp3339D339DgaCgaT11AY.820.001357
ORF1ab/nsp3339D339DgaCgaT11AY.850.000427
ORF1ab/nsp3339D339DgaCgaT11AY.920.000287
ORF1ab/nsp3339D339DgaCgaT11B.1.1.1530.001095
ORF1ab/nsp3339D339DgaCgaT11B.1.1.1610.003534
ORF1ab/nsp3339D339DgaCgaT11B.1.1.1890.001513
ORF1ab/nsp3339D339DgaCgaT11B.1.1.2160.00089
ORF1ab/nsp3339D339DgaCgaT11B.1.1.2180.007692
ORF1ab/nsp3339D339DgaCgaT11B.1.1.2190.005
ORF1ab/nsp3339D339DgaCgaT11B.1.1.2200.001859
ORF1ab/nsp3339D339DgaCgaT11B.1.1.2310.003096
ORF1ab/nsp3339D339DgaCgaT11B.1.1.2730.006757
ORF1ab/nsp3339D339DgaCgaT11B.1.1.3080.011765
ORF1ab/nsp3339D339DgaCgaT11B.1.1.3160.000925
ORF1ab/nsp3339D339DgaCgaT11B.1.1.3480.000796
ORF1ab/nsp3339D339DgaCgaT11B.1.1.3710.010417
ORF1ab/nsp3339D339DgaCgaT11B.1.1.3760.005952
ORF1ab/nsp3339D339DgaCgaT11B.1.1.4040.015873
ORF1ab/nsp3339D339DgaCgaT11B.1.1.4090.002833
ORF1ab/nsp3339D339DgaCgaT11B.1.1.4200.001006
ORF1ab/nsp3339D339DgaCgaT11B.1.1.4660.008696
ORF1ab/nsp3339D339DgaCgaT11B.1.1.500.000679
ORF1ab/nsp3339D339DgaCgaT11B.1.1.5070.008696
ORF1ab/nsp3339D339DgaCgaT11B.1.1.5210.005348
ORF1ab/nsp3339D339DgaCgaT11B.1.1200.007692
ORF1ab/nsp3339D339DgaCgaT11B.1.1270.002198
ORF1ab/nsp3339D339DgaCgaT11B.1.160.320.004292
ORF1ab/nsp3339D339DgaCgaT11B.1.177.100.000878
ORF1ab/nsp3339D339DgaCgaT11B.1.177.160.000664
ORF1ab/nsp3339D339DgaCgaT11B.1.177.350.000691
ORF1ab/nsp3339D339DgaCgaT11B.1.177.40.000211
ORF1ab/nsp3339D339DgaCgaT11B.1.177.560.000668
ORF1ab/nsp3339D339DgaCgaT11B.1.177.810.000189
ORF1ab/nsp3339D339DgaCgaT11B.1.177.860.000183
ORF1ab/nsp3339D339DgaCgaT11B.1.177.870.000728
ORF1ab/nsp3339D339DgaCgaT11B.1.3240.001605
ORF1ab/nsp3339D339DgaCgaT11B.1.3320.003497
ORF1ab/nsp3339D339DgaCgaT11B.1.360.000146
ORF1ab/nsp3339D339DgaCgaT11B.1.36.350.002604
ORF1ab/nsp3339D339DgaCgaT11B.1.3610.001289
ORF1ab/nsp3339D339DgaCgaT11B.1.4260.001009
ORF1ab/nsp3339D339DgaCgaT11B.1.438.10.000107
ORF1ab/nsp3339D339DgaCgaT11B.1.4660.023256
ORF1ab/nsp3339D339DgaCgaT11B.1.466.10.007194
ORF1ab/nsp3339D339DgaCgaT11B.1.4680.005714
ORF1ab/nsp3339D339DgaCgaT11B.1.5760.000907
ORF1ab/nsp3339D339DgaCgaT11B.1.5950.000261
ORF1ab/nsp3339D339DgaCgaT11B.1.596.10.009346
ORF1ab/nsp3339D339DgaCgaT11B.1.617.10.000129
ORF1ab/nsp3339D339DgaCgaT11B.1.6250.002353
ORF1ab/nsp3339D339DgaCgaT11B.390.002331
ORF1ab/nsp3339D339DgaCgaT11B.6.60.000889
ORF1ab/nsp3339D339DgaCgaT11C.36.30.000567
ORF1ab/nsp3339D339DgaCgaT11P.1.170.000162
ORF1ab/nsp3339D339DgaCgaT11P.1.20.001156
ORF1ab/nsp3339D339DgaCgaT11Q.70.001111
ORF1ab/nsp3339D339DgaCgaT11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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