CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = D1774G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31774D1774GD2592GnonsyngAtgGt60860818039-8041

Details of the mutation D1774G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31774D1774GgAtgGt608608All0.000116
ORF1ab/nsp31774D1774GgAtgGt248248AY.23.10.103506
ORF1ab/nsp31774D1774GgAtgGt5959B.1.1.70.000053
ORF1ab/nsp31774D1774GgAtgGt3636B.1.20.000317
ORF1ab/nsp31774D1774GgAtgGt2121AY.40.000033
ORF1ab/nsp31774D1774GgAtgGt1717B.1.617.20.000064
ORF1ab/nsp31774D1774GgAtgGt1515B.1.4290.000353
ORF1ab/nsp31774D1774GgAtgGt1313AY.1030.000081
ORF1ab/nsp31774D1774GgAtgGt1313AY.250.000078
ORF1ab/nsp31774D1774GgAtgGt1010AY.440.000061
ORF1ab/nsp31774D1774GgAtgGt1010B.1.3110.002746
ORF1ab/nsp31774D1774GgAtgGt88AY.360.001186
ORF1ab/nsp31774D1774GgAtgGt77B.1.1770.000092
ORF1ab/nsp31774D1774GgAtgGt77B.1.3510.000208
ORF1ab/nsp31774D1774GgAtgGt77B.1.5960.00061
ORF1ab/nsp31774D1774GgAtgGt77B.1.617.10.000903
ORF1ab/nsp31774D1774GgAtgGt66AY.430.000027
ORF1ab/nsp31774D1774GgAtgGt55AY.1190.000177
ORF1ab/nsp31774D1774GgAtgGt55AY.290.000079
ORF1ab/nsp31774D1774GgAtgGt55AY.9.20.000184
ORF1ab/nsp31774D1774GgAtgGt55B.10.000046
ORF1ab/nsp31774D1774GgAtgGt44AY.230.000279
ORF1ab/nsp31774D1774GgAtgGt44AY.330.000267
ORF1ab/nsp31774D1774GgAtgGt44B.1.10.000073
ORF1ab/nsp31774D1774GgAtgGt44R.10.00036
ORF1ab/nsp31774D1774GgAtgGt33AY.46.20.001906
ORF1ab/nsp31774D1774GgAtgGt33B.1.1.3650.01676
ORF1ab/nsp31774D1774GgAtgGt33B.1.177.350.002073
ORF1ab/nsp31774D1774GgAtgGt33B.360.230769
ORF1ab/nsp31774D1774GgAtgGt22AY.1000.000092
ORF1ab/nsp31774D1774GgAtgGt22AY.270.000129
ORF1ab/nsp31774D1774GgAtgGt22AY.460.000208
ORF1ab/nsp31774D1774GgAtgGt22AY.46.60.000144
ORF1ab/nsp31774D1774GgAtgGt22AY.550.001835
ORF1ab/nsp31774D1774GgAtgGt22AY.7.20.001119
ORF1ab/nsp31774D1774GgAtgGt22AY.930.000546
ORF1ab/nsp31774D1774GgAtgGt22AY.99.20.000184
ORF1ab/nsp31774D1774GgAtgGt22B.1.1.250.001137
ORF1ab/nsp31774D1774GgAtgGt22B.1.1.280.000622
ORF1ab/nsp31774D1774GgAtgGt22B.1.1.3060.000877
ORF1ab/nsp31774D1774GgAtgGt22B.1.1.5190.000079
ORF1ab/nsp31774D1774GgAtgGt22B.1.2320.001075
ORF1ab/nsp31774D1774GgAtgGt22B.1.5400.019417
ORF1ab/nsp31774D1774GgAtgGt22B.1.6210.000177
ORF1ab/nsp31774D1774GgAtgGt22B.1.6280.000705
ORF1ab/nsp31774D1774GgAtgGt22P.1.10.000635
ORF1ab/nsp31774D1774GgAtgGt110.055556
ORF1ab/nsp31774D1774GgAtgGt11A.2.40.003367
ORF1ab/nsp31774D1774GgAtgGt11AY.1170.000085
ORF1ab/nsp31774D1774GgAtgGt11AY.1180.000063
ORF1ab/nsp31774D1774GgAtgGt11AY.130.000161
ORF1ab/nsp31774D1774GgAtgGt11AY.16.10.00047
ORF1ab/nsp31774D1774GgAtgGt11AY.260.000028
ORF1ab/nsp31774D1774GgAtgGt11AY.340.000097
ORF1ab/nsp31774D1774GgAtgGt11AY.39.20.001541
ORF1ab/nsp31774D1774GgAtgGt11AY.4.20.000022
ORF1ab/nsp31774D1774GgAtgGt11AY.4.2.10.000149
ORF1ab/nsp31774D1774GgAtgGt11AY.420.00004
ORF1ab/nsp31774D1774GgAtgGt11AY.530.000288
ORF1ab/nsp31774D1774GgAtgGt11AY.60.000041
ORF1ab/nsp31774D1774GgAtgGt11AY.610.000105
ORF1ab/nsp31774D1774GgAtgGt11AY.690.000187
ORF1ab/nsp31774D1774GgAtgGt11AY.740.000116
ORF1ab/nsp31774D1774GgAtgGt11AY.750.000056
ORF1ab/nsp31774D1774GgAtgGt11AY.840.000437
ORF1ab/nsp31774D1774GgAtgGt11AY.90.000068
ORF1ab/nsp31774D1774GgAtgGt11AY.9.10.000084
ORF1ab/nsp31774D1774GgAtgGt11AY.990.001049
ORF1ab/nsp31774D1774GgAtgGt11AZ.40.003356
ORF1ab/nsp31774D1774GgAtgGt11B.1.1.2140.000055
ORF1ab/nsp31774D1774GgAtgGt11B.1.1.370.000193
ORF1ab/nsp31774D1774GgAtgGt11B.1.1.390.00051
ORF1ab/nsp31774D1774GgAtgGt11B.1.1600.000031
ORF1ab/nsp31774D1774GgAtgGt11B.1.177.830.001481
ORF1ab/nsp31774D1774GgAtgGt11B.1.177.90.001332
ORF1ab/nsp31774D1774GgAtgGt11B.1.2340.000132
ORF1ab/nsp31774D1774GgAtgGt11B.1.2600.003344
ORF1ab/nsp31774D1774GgAtgGt11B.1.3370.005587
ORF1ab/nsp31774D1774GgAtgGt11B.1.3670.000792
ORF1ab/nsp31774D1774GgAtgGt11B.1.4230.010204
ORF1ab/nsp31774D1774GgAtgGt11B.1.4270.00005
ORF1ab/nsp31774D1774GgAtgGt11B.1.438.10.000107
ORF1ab/nsp31774D1774GgAtgGt11B.1.5210.004975
ORF1ab/nsp31774D1774GgAtgGt11B.1.5610.000397
ORF1ab/nsp31774D1774GgAtgGt11B.1.5680.001111
ORF1ab/nsp31774D1774GgAtgGt11B.1.6370.000073
ORF1ab/nsp31774D1774GgAtgGt11P.10.000016
ORF1ab/nsp31774D1774GgAtgGt11P.1.170.000162

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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