CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = D112E

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3112D112ED930EnonsyngaTgaA93660.7096773053-3055
ORF1ab/nsp3112D112ED930EnonsyngaTgaG93270.2903233053-3055

Details of the mutation D112E within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3112D112EgaTgaA6693All0.000013
ORF1ab/nsp3112D112EgaTgaG2793All0.000005
ORF1ab/nsp3112D112EgaTgaA4344B.1.1.70.000038
ORF1ab/nsp3112D112EgaTgaG144B.1.1.70.000001
ORF1ab/nsp3112D112EgaTgaA1010AY.430.000044
ORF1ab/nsp3112D112EgaTgaG77AY.440.000043
ORF1ab/nsp3112D112EgaTgaG36B.10.000027
ORF1ab/nsp3112D112EgaTgaA36B.10.000027
ORF1ab/nsp3112D112EgaTgaG33B.1.360.000438
ORF1ab/nsp3112D112EgaTgaA12AY.1050.000643
ORF1ab/nsp3112D112EgaTgaG12AY.1050.000643
ORF1ab/nsp3112D112EgaTgaG22B.1.1.2370.010811
ORF1ab/nsp3112D112EgaTgaG22B.1.2210.000142
ORF1ab/nsp3112D112EgaTgaG11A.60.005128
ORF1ab/nsp3112D112EgaTgaA11AY.1040.001984
ORF1ab/nsp3112D112EgaTgaA11AY.200.000039
ORF1ab/nsp3112D112EgaTgaA11AY.390.000025
ORF1ab/nsp3112D112EgaTgaG11AY.840.000437
ORF1ab/nsp3112D112EgaTgaG11B.1.1.2160.00089
ORF1ab/nsp3112D112EgaTgaA11B.1.1.370.000193
ORF1ab/nsp3112D112EgaTgaG11B.1.1.500.000679
ORF1ab/nsp3112D112EgaTgaA11B.1.1770.000013
ORF1ab/nsp3112D112EgaTgaA11B.1.258.110.000396
ORF1ab/nsp3112D112EgaTgaG11B.1.258.170.000104
ORF1ab/nsp3112D112EgaTgaG11B.1.36.380.001642
ORF1ab/nsp3112D112EgaTgaA11B.1.4000.000429
ORF1ab/nsp3112D112EgaTgaA11B.1.4260.001009
ORF1ab/nsp3112D112EgaTgaG11B.1.5250.000113
ORF1ab/nsp3112D112EgaTgaG11B.1.5610.000397
ORF1ab/nsp3112D112EgaTgaA11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.