CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = D1085Y

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31085D1085YD1903YnonsynGacTac5575560.9982055972-5974
ORF1ab/nsp31085D1085YD1903YnonsynGaCTaT55710.001795335972-5974

Details of the mutation D1085Y within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31085D1085YGacTac556557All0.000106
ORF1ab/nsp31085D1085YGaCTaT1557All0
ORF1ab/nsp31085D1085YGacTac9393AY.250.000559
ORF1ab/nsp31085D1085YGacTac7070B.1.1.70.000063
ORF1ab/nsp31085D1085YGacTac6161B.10.000559
ORF1ab/nsp31085D1085YGacTac4646AY.430.000204
ORF1ab/nsp31085D1085YGacTac3434B.1.617.20.000128
ORF1ab/nsp31085D1085YGacTac2121AY.40.000033
ORF1ab/nsp31085D1085YGacTac1818AY.560.028892
ORF1ab/nsp31085D1085YGacTac1313B.1.4290.000306
ORF1ab/nsp31085D1085YGacTac1111AY.440.000067
ORF1ab/nsp31085D1085YGacTac1111B.1.1.330.00463
ORF1ab/nsp31085D1085YGacTac1010AY.1030.000062
ORF1ab/nsp31085D1085YGacTac1010B.1.3510.000297
ORF1ab/nsp31085D1085YGacTac99B.1.20.000079
ORF1ab/nsp31085D1085YGacTac88AY.46.60.000578
ORF1ab/nsp31085D1085YGacTac88B.1.10.000145
ORF1ab/nsp31085D1085YGacTac77AY.330.000467
ORF1ab/nsp31085D1085YGacTac77B.1.1.2220.001428
ORF1ab/nsp31085D1085YGacTac55A.2.50.002495
ORF1ab/nsp31085D1085YGacTac55AY.70.00098
ORF1ab/nsp31085D1085YGacTac55AY.750.00028
ORF1ab/nsp31085D1085YGacTac55B.1.177.80.003762
ORF1ab/nsp31085D1085YGacTac55B.1.36.120.048077
ORF1ab/nsp31085D1085YGacTac44AY.116.10.001246
ORF1ab/nsp31085D1085YGacTac44AY.470.000124
ORF1ab/nsp31085D1085YGacTac44AY.540.000381
ORF1ab/nsp31085D1085YGacTac44B.1.1770.000053
ORF1ab/nsp31085D1085YGacTac44P.10.000063
ORF1ab/nsp31085D1085YGacTac33AY.1200.000112
ORF1ab/nsp31085D1085YGacTac33AY.200.000117
ORF1ab/nsp31085D1085YGacTac33AY.390.000074
ORF1ab/nsp31085D1085YGacTac33B.1.360.000438
ORF1ab/nsp31085D1085YGacTac33B.1.36.160.004274
ORF1ab/nsp31085D1085YGacTac33D.20.000225
ORF1ab/nsp31085D1085YGacTac22AY.1180.000125
ORF1ab/nsp31085D1085YGacTac22AY.1210.000271
ORF1ab/nsp31085D1085YGacTac22AY.260.000057
ORF1ab/nsp31085D1085YGacTac22AY.30.00002
ORF1ab/nsp31085D1085YGacTac22AY.360.000296
ORF1ab/nsp31085D1085YGacTac22AY.4.20.000043
ORF1ab/nsp31085D1085YGacTac22AY.50.000041
ORF1ab/nsp31085D1085YGaCTaT12AY.850.000427
ORF1ab/nsp31085D1085YGacTac12AY.850.000427
ORF1ab/nsp31085D1085YGacTac22B.1.2210.000142
ORF1ab/nsp31085D1085YGacTac22B.1.5210.00995
ORF1ab/nsp31085D1085YGacTac22P.1.140.000096
ORF1ab/nsp31085D1085YGacTac11AY.1020.000027
ORF1ab/nsp31085D1085YGacTac11AY.120.10.000321
ORF1ab/nsp31085D1085YGacTac11AY.130.000161
ORF1ab/nsp31085D1085YGacTac11AY.16.10.00047
ORF1ab/nsp31085D1085YGacTac11AY.220.002092
ORF1ab/nsp31085D1085YGacTac11AY.270.000065
ORF1ab/nsp31085D1085YGacTac11AY.290.000016
ORF1ab/nsp31085D1085YGacTac11AY.39.10.00004
ORF1ab/nsp31085D1085YGacTac11AY.450.000122
ORF1ab/nsp31085D1085YGacTac11AY.60.000041
ORF1ab/nsp31085D1085YGacTac11AY.690.000187
ORF1ab/nsp31085D1085YGacTac11AY.90.000068
ORF1ab/nsp31085D1085YGacTac11AY.9.10.000084
ORF1ab/nsp31085D1085YGacTac11AY.900.000684
ORF1ab/nsp31085D1085YGacTac11AY.99.20.000092
ORF1ab/nsp31085D1085YGacTac11AZ.20.000821
ORF1ab/nsp31085D1085YGacTac11B0.000128
ORF1ab/nsp31085D1085YGacTac11B.1.1.10.000327
ORF1ab/nsp31085D1085YGacTac11B.1.1.1170.009709
ORF1ab/nsp31085D1085YGacTac11B.1.1.2160.00089
ORF1ab/nsp31085D1085YGacTac11B.1.1.2410.00207
ORF1ab/nsp31085D1085YGacTac11B.1.1.280.000311
ORF1ab/nsp31085D1085YGacTac11B.1.1.3180.000302
ORF1ab/nsp31085D1085YGacTac11B.1.1.570.011494
ORF1ab/nsp31085D1085YGacTac11B.1.1600.000031
ORF1ab/nsp31085D1085YGacTac11B.1.2930.0125
ORF1ab/nsp31085D1085YGacTac11B.1.3950.007042
ORF1ab/nsp31085D1085YGacTac11B.1.5260.000024
ORF1ab/nsp31085D1085YGacTac11B.1.5770.000687
ORF1ab/nsp31085D1085YGacTac11B.1.621.10.000506
ORF1ab/nsp31085D1085YGacTac11C.360.000911
ORF1ab/nsp31085D1085YGacTac11C.36.3.10.002717
ORF1ab/nsp31085D1085YGacTac11C.370.000116
ORF1ab/nsp31085D1085YGacTac11P.1.170.000162
ORF1ab/nsp31085D1085YGacTac11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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