CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = D1085N

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31085D1085ND1903NnonsynGacAac1671630.9760485972-5974
ORF1ab/nsp31085D1085ND1903NnonsynGaCAaT16740.02395215972-5974

Details of the mutation D1085N within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31085D1085NGacAac163167All0.000031
ORF1ab/nsp31085D1085NGaCAaT4167All0.000001
ORF1ab/nsp31085D1085NGacAac2828B.1.1770.000369
ORF1ab/nsp31085D1085NGacAac2020B.1.1.70.000018
ORF1ab/nsp31085D1085NGacAac1414B.1.617.20.000053
ORF1ab/nsp31085D1085NGacAac1212AY.40.000019
ORF1ab/nsp31085D1085NGacAac1010B.1.258.170.00104
ORF1ab/nsp31085D1085NGacAac99B.1.4290.000212
ORF1ab/nsp31085D1085NGacAac77AY.60.000288
ORF1ab/nsp31085D1085NGacAac66B.1.177.230.019417
ORF1ab/nsp31085D1085NGacAac44AY.440.000024
ORF1ab/nsp31085D1085NGacAac44B.1.10.000073
ORF1ab/nsp31085D1085NGacAac44P.10.000063
ORF1ab/nsp31085D1085NGacAac33AY.460.000312
ORF1ab/nsp31085D1085NGacAac33B.10.000027
ORF1ab/nsp31085D1085NGacAac220.111111
ORF1ab/nsp31085D1085NGacAac22AY.1020.000053
ORF1ab/nsp31085D1085NGaCAaT12AY.1190.000035
ORF1ab/nsp31085D1085NGacAac12AY.1190.000035
ORF1ab/nsp31085D1085NGacAac22AY.250.000012
ORF1ab/nsp31085D1085NGacAac22AY.4.50.000215
ORF1ab/nsp31085D1085NGacAac22AY.430.000009
ORF1ab/nsp31085D1085NGacAac22B.1.1.2250.014388
ORF1ab/nsp31085D1085NGacAac22B.1.1.700.000682
ORF1ab/nsp31085D1085NGacAac22B.1.20.000018
ORF1ab/nsp31085D1085NGacAac11A0.000387
ORF1ab/nsp31085D1085NGacAac11A.300.142857
ORF1ab/nsp31085D1085NGacAac11AY.1030.000006
ORF1ab/nsp31085D1085NGacAac11AY.1050.000643
ORF1ab/nsp31085D1085NGaCAaT11AY.120.10.000321
ORF1ab/nsp31085D1085NGaCAaT11AY.120.20.001285
ORF1ab/nsp31085D1085NGacAac11AY.260.000028
ORF1ab/nsp31085D1085NGacAac11AY.30.00001
ORF1ab/nsp31085D1085NGacAac11AY.340.000097
ORF1ab/nsp31085D1085NGacAac11AY.39.10.00004
ORF1ab/nsp31085D1085NGacAac11AY.46.60.000072
ORF1ab/nsp31085D1085NGacAac11AY.750.000056
ORF1ab/nsp31085D1085NGacAac11AY.920.000287
ORF1ab/nsp31085D1085NGacAac11AY.99.20.000092
ORF1ab/nsp31085D1085NGacAac11AZ.30.00152
ORF1ab/nsp31085D1085NGacAac11B.1.1.2200.001859
ORF1ab/nsp31085D1085NGacAac11B.1.1.4060.006494
ORF1ab/nsp31085D1085NGacAac11B.1.177.570.000281
ORF1ab/nsp31085D1085NGacAac11B.1.2430.00007
ORF1ab/nsp31085D1085NGacAac11B.1.360.000146
ORF1ab/nsp31085D1085NGacAac11B.1.5250.000113
ORF1ab/nsp31085D1085NGaCAaT11B.1.5960.000087
ORF1ab/nsp31085D1085NGacAac11B.1.617.10.000129
ORF1ab/nsp31085D1085NGacAac11C.60.037037
ORF1ab/nsp31085D1085NGacAac11P.1.160.000374

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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