CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = C1223C

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31223C1223CC2041CsyntgCtgT2985298516386-6388

Details of the mutation C1223C within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31223C1223CtgCtgT29852985All0.000571
ORF1ab/nsp31223C1223CtgCtgT14261426AY.640.84881
ORF1ab/nsp31223C1223CtgCtgT331331B.1.1.70.000296
ORF1ab/nsp31223C1223CtgCtgT176176B.1.177.210.013459
ORF1ab/nsp31223C1223CtgCtgT120120B.1.617.20.000452
ORF1ab/nsp31223C1223CtgCtgT9696AY.40.000149
ORF1ab/nsp31223C1223CtgCtgT6969AY.30.000686
ORF1ab/nsp31223C1223CtgCtgT6565AY.430.000288
ORF1ab/nsp31223C1223CtgCtgT5757B.1.1.3020.118257
ORF1ab/nsp31223C1223CtgCtgT5050B.1.20.00044
ORF1ab/nsp31223C1223CtgCtgT4848B.1.177.420.042934
ORF1ab/nsp31223C1223CtgCtgT3434B.10.000311
ORF1ab/nsp31223C1223CtgCtgT2525AY.250.00015
ORF1ab/nsp31223C1223CtgCtgT2424AY.1030.000149
ORF1ab/nsp31223C1223CtgCtgT2222AY.440.000134
ORF1ab/nsp31223C1223CtgCtgT2121B.1.1.5190.000834
ORF1ab/nsp31223C1223CtgCtgT1919B.1.10.000345
ORF1ab/nsp31223C1223CtgCtgT1818AY.650.009595
ORF1ab/nsp31223C1223CtgCtgT1818P.10.000284
ORF1ab/nsp31223C1223CtgCtgT1717AY.4.20.000369
ORF1ab/nsp31223C1223CtgCtgT1313AY.1170.001099
ORF1ab/nsp31223C1223CtgCtgT1212AY.240.005172
ORF1ab/nsp31223C1223CtgCtgT1212AY.260.00034
ORF1ab/nsp31223C1223CtgCtgT1111B.1.2430.000765
ORF1ab/nsp31223C1223CtgCtgT1010B.1.1600.000312
ORF1ab/nsp31223C1223CtgCtgT1010B.1.1770.000132
ORF1ab/nsp31223C1223CtgCtgT99AY.130.001449
ORF1ab/nsp31223C1223CtgCtgT88AY.750.000448
ORF1ab/nsp31223C1223CtgCtgT88B.1.258.230.190476
ORF1ab/nsp31223C1223CtgCtgT88B.1.5950.002088
ORF1ab/nsp31223C1223CtgCtgT77AY.1000.000322
ORF1ab/nsp31223C1223CtgCtgT77AY.400.00675
ORF1ab/nsp31223C1223CtgCtgT77B.1.3510.000208
ORF1ab/nsp31223C1223CtgCtgT77B.1.5260.000165
ORF1ab/nsp31223C1223CtgCtgT77B.1.6370.000512
ORF1ab/nsp31223C1223CtgCtgT77Q.80.001154
ORF1ab/nsp31223C1223CtgCtgT66AY.1020.000159
ORF1ab/nsp31223C1223CtgCtgT66AY.1080.006615
ORF1ab/nsp31223C1223CtgCtgT66AY.50.000124
ORF1ab/nsp31223C1223CtgCtgT55AY.1190.000177
ORF1ab/nsp31223C1223CtgCtgT55AY.390.000124
ORF1ab/nsp31223C1223CtgCtgT55AY.940.002213
ORF1ab/nsp31223C1223CtgCtgT55B.1.1.280.001556
ORF1ab/nsp31223C1223CtgCtgT55B.1.1.330.002104
ORF1ab/nsp31223C1223CtgCtgT55B.1.1.3690.002231
ORF1ab/nsp31223C1223CtgCtgT55B.1.4270.000252
ORF1ab/nsp31223C1223CtgCtgT44AY.39.10.000158
ORF1ab/nsp31223C1223CtgCtgT44AY.670.001857
ORF1ab/nsp31223C1223CtgCtgT44AY.90.00027
ORF1ab/nsp31223C1223CtgCtgT44AY.9.20.000147
ORF1ab/nsp31223C1223CtgCtgT44B.1.1.4290.018433
ORF1ab/nsp31223C1223CtgCtgT44B.1.1.750.042553
ORF1ab/nsp31223C1223CtgCtgT44B.1.177.150.002524
ORF1ab/nsp31223C1223CtgCtgT44B.1.360.000584
ORF1ab/nsp31223C1223CtgCtgT44R.10.00036
ORF1ab/nsp31223C1223CtgCtgT33AY.100.00159
ORF1ab/nsp31223C1223CtgCtgT33AY.1100.000338
ORF1ab/nsp31223C1223CtgCtgT33AY.1200.000112
ORF1ab/nsp31223C1223CtgCtgT33AY.140.000264
ORF1ab/nsp31223C1223CtgCtgT33AY.200.000117
ORF1ab/nsp31223C1223CtgCtgT33AY.290.000047
ORF1ab/nsp31223C1223CtgCtgT33B.1.2210.000213
ORF1ab/nsp31223C1223CtgCtgT33B.1.4390.017751
ORF1ab/nsp31223C1223CtgCtgT33B.1.5250.000339
ORF1ab/nsp31223C1223CtgCtgT33B.1.5610.001191
ORF1ab/nsp31223C1223CtgCtgT22AY.1210.000271
ORF1ab/nsp31223C1223CtgCtgT22AY.330.000134
ORF1ab/nsp31223C1223CtgCtgT22AY.380.000999
ORF1ab/nsp31223C1223CtgCtgT22AY.420.00008
ORF1ab/nsp31223C1223CtgCtgT22AY.46.20.001271
ORF1ab/nsp31223C1223CtgCtgT22AY.5.30.000675
ORF1ab/nsp31223C1223CtgCtgT22AY.600.001876
ORF1ab/nsp31223C1223CtgCtgT22AY.610.00021
ORF1ab/nsp31223C1223CtgCtgT22B0.000256
ORF1ab/nsp31223C1223CtgCtgT22B.1.1.630.000772
ORF1ab/nsp31223C1223CtgCtgT22B.1.177.120.000303
ORF1ab/nsp31223C1223CtgCtgT22B.1.177.620.002384
ORF1ab/nsp31223C1223CtgCtgT22B.1.4290.000047
ORF1ab/nsp31223C1223CtgCtgT22B.1.5960.000174
ORF1ab/nsp31223C1223CtgCtgT22P.1.120.000968
ORF1ab/nsp31223C1223CtgCtgT22P.1.140.000096
ORF1ab/nsp31223C1223CtgCtgT22P.20.000373
ORF1ab/nsp31223C1223CtgCtgT11A.10.000282
ORF1ab/nsp31223C1223CtgCtgT11A.2.40.003367
ORF1ab/nsp31223C1223CtgCtgT11A.23.10.000704
ORF1ab/nsp31223C1223CtgCtgT11AY.1050.000643
ORF1ab/nsp31223C1223CtgCtgT11AY.1070.000466
ORF1ab/nsp31223C1223CtgCtgT11AY.1160.000287
ORF1ab/nsp31223C1223CtgCtgT11AY.120.10.000321
ORF1ab/nsp31223C1223CtgCtgT11AY.16.10.00047
ORF1ab/nsp31223C1223CtgCtgT11AY.23.10.000417
ORF1ab/nsp31223C1223CtgCtgT11AY.300.000396
ORF1ab/nsp31223C1223CtgCtgT11AY.370.000316
ORF1ab/nsp31223C1223CtgCtgT11AY.4.2.10.000149
ORF1ab/nsp31223C1223CtgCtgT11AY.4.50.000107
ORF1ab/nsp31223C1223CtgCtgT11AY.450.000122
ORF1ab/nsp31223C1223CtgCtgT11AY.46.60.000072
ORF1ab/nsp31223C1223CtgCtgT11AY.470.000031
ORF1ab/nsp31223C1223CtgCtgT11AY.540.000095
ORF1ab/nsp31223C1223CtgCtgT11AY.570.000656
ORF1ab/nsp31223C1223CtgCtgT11AY.590.00053
ORF1ab/nsp31223C1223CtgCtgT11AY.60.000041
ORF1ab/nsp31223C1223CtgCtgT11AY.620.000436
ORF1ab/nsp31223C1223CtgCtgT11AY.690.000187
ORF1ab/nsp31223C1223CtgCtgT11AY.70.000196
ORF1ab/nsp31223C1223CtgCtgT11AY.730.000665
ORF1ab/nsp31223C1223CtgCtgT11AY.740.000116
ORF1ab/nsp31223C1223CtgCtgT11AY.75.10.00018
ORF1ab/nsp31223C1223CtgCtgT11AY.98.10.000048
ORF1ab/nsp31223C1223CtgCtgT11AY.99.20.000092
ORF1ab/nsp31223C1223CtgCtgT11B.1.1.1920.002309
ORF1ab/nsp31223C1223CtgCtgT11B.1.1.3160.000925
ORF1ab/nsp31223C1223CtgCtgT11B.1.1.3170.000412
ORF1ab/nsp31223C1223CtgCtgT11B.1.1.5230.001563
ORF1ab/nsp31223C1223CtgCtgT11B.1.160.170.001701
ORF1ab/nsp31223C1223CtgCtgT11B.1.177.520.001757
ORF1ab/nsp31223C1223CtgCtgT11B.1.177.600.000218
ORF1ab/nsp31223C1223CtgCtgT11B.1.177.730.000566
ORF1ab/nsp31223C1223CtgCtgT11B.1.220.001318
ORF1ab/nsp31223C1223CtgCtgT11B.1.2650.001271
ORF1ab/nsp31223C1223CtgCtgT11B.1.351.20.000303
ORF1ab/nsp31223C1223CtgCtgT11B.1.351.50.0006
ORF1ab/nsp31223C1223CtgCtgT11B.1.3560.001727
ORF1ab/nsp31223C1223CtgCtgT11B.1.36.180.00042
ORF1ab/nsp31223C1223CtgCtgT11B.1.3690.000285
ORF1ab/nsp31223C1223CtgCtgT11B.1.3810.007812
ORF1ab/nsp31223C1223CtgCtgT11B.1.3960.000706
ORF1ab/nsp31223C1223CtgCtgT11B.1.438.10.000107
ORF1ab/nsp31223C1223CtgCtgT11B.1.617.10.000129
ORF1ab/nsp31223C1223CtgCtgT11B.1.6280.000352
ORF1ab/nsp31223C1223CtgCtgT11B.6.50.076923
ORF1ab/nsp31223C1223CtgCtgT11C.370.000116
ORF1ab/nsp31223C1223CtgCtgT11P.1.10.000318
ORF1ab/nsp31223C1223CtgCtgT11P.1.100.000269
ORF1ab/nsp31223C1223CtgCtgT11V.20.032258

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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