CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = A225V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3225A225VA1043VnonsyngCagTa2171217113392-3394

Details of the mutation A225V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3225A225VgCagTa21712171All0.000415
ORF1ab/nsp3225A225VgCagTa205205B.1.1.1860.704467
ORF1ab/nsp3225A225VgCagTa204204B.1.1.70.000183
ORF1ab/nsp3225A225VgCagTa190190B.1.1770.002502
ORF1ab/nsp3225A225VgCagTa145145B.1.617.20.000546
ORF1ab/nsp3225A225VgCagTa117117AY.40.000182
ORF1ab/nsp3225A225VgCagTa9797AY.250.000583
ORF1ab/nsp3225A225VgCagTa8686AY.430.000381
ORF1ab/nsp3225A225VgCagTa7676B.1.1600.00237
ORF1ab/nsp3225A225VgCagTa5757B.1.20.000502
ORF1ab/nsp3225A225VgCagTa5757B.1.5960.004967
ORF1ab/nsp3225A225VgCagTa5454AY.50.001115
ORF1ab/nsp3225A225VgCagTa5151AY.1200.001896
ORF1ab/nsp3225A225VgCagTa4545B.10.000412
ORF1ab/nsp3225A225VgCagTa4444B.1.1.2220.008976
ORF1ab/nsp3225A225VgCagTa4242B.1.177.210.003212
ORF1ab/nsp3225A225VgCagTa4040AY.390.000988
ORF1ab/nsp3225A225VgCagTa3939B.1.36.220.047101
ORF1ab/nsp3225A225VgCagTa3838AY.440.000231
ORF1ab/nsp3225A225VgCagTa3737B.1.2410.030032
ORF1ab/nsp3225A225VgCagTa3030B.1.4290.000706
ORF1ab/nsp3225A225VgCagTa2929B.1.10.000526
ORF1ab/nsp3225A225VgCagTa2323AY.1030.000143
ORF1ab/nsp3225A225VgCagTa2222B.1.177.100.019315
ORF1ab/nsp3225A225VgCagTa1919B.1.3510.000565
ORF1ab/nsp3225A225VgCagTa1717B.1.2580.001131
ORF1ab/nsp3225A225VgCagTa1313AY.30.000129
ORF1ab/nsp3225A225VgCagTa1212AY.4.50.00129
ORF1ab/nsp3225A225VgCagTa1212B.1.2430.000835
ORF1ab/nsp3225A225VgCagTa1111AY.460.001145
ORF1ab/nsp3225A225VgCagTa1111AY.99.20.001014
ORF1ab/nsp3225A225VgCagTa1111B.1.1990.045455
ORF1ab/nsp3225A225VgCagTa1010AY.470.000311
ORF1ab/nsp3225A225VgCagTa1010P.10.000158
ORF1ab/nsp3225A225VgCagTa99B.1.1.5260.031915
ORF1ab/nsp3225A225VgCagTa88AY.200.000311
ORF1ab/nsp3225A225VgCagTa88AY.750.000448
ORF1ab/nsp3225A225VgCagTa88Q.70.008889
ORF1ab/nsp3225A225VgCagTa77AY.330.000467
ORF1ab/nsp3225A225VgCagTa77AY.4.20.000152
ORF1ab/nsp3225A225VgCagTa77AY.920.002011
ORF1ab/nsp3225A225VgCagTa77B.1.6210.00062
ORF1ab/nsp3225A225VgCagTa77P.1.17.10.006124
ORF1ab/nsp3225A225VgCagTa66AY.1140.001387
ORF1ab/nsp3225A225VgCagTa66AY.290.000095
ORF1ab/nsp3225A225VgCagTa66B.1.1.1920.013857
ORF1ab/nsp3225A225VgCagTa66B.1.1.2140.000333
ORF1ab/nsp3225A225VgCagTa66B.1.5090.005195
ORF1ab/nsp3225A225VgCagTa66B.1.5260.000141
ORF1ab/nsp3225A225VgCagTa55AY.260.000142
ORF1ab/nsp3225A225VgCagTa55AY.98.10.000242
ORF1ab/nsp3225A225VgCagTa55C.370.00058
ORF1ab/nsp3225A225VgCagTa44AY.1020.000106
ORF1ab/nsp3225A225VgCagTa44AY.3.10.000341
ORF1ab/nsp3225A225VgCagTa44AY.46.10.004107
ORF1ab/nsp3225A225VgCagTa44AY.610.000419
ORF1ab/nsp3225A225VgCagTa44B.1.1.4320.005063
ORF1ab/nsp3225A225VgCagTa44B.1.2340.000528
ORF1ab/nsp3225A225VgCagTa44B.1.6090.001918
ORF1ab/nsp3225A225VgCagTa33AY.1000.000138
ORF1ab/nsp3225A225VgCagTa33AY.1170.000254
ORF1ab/nsp3225A225VgCagTa33AY.130.000483
ORF1ab/nsp3225A225VgCagTa33AY.450.000365
ORF1ab/nsp3225A225VgCagTa33AY.840.001312
ORF1ab/nsp3225A225VgCagTa33B.1.1.280.000934
ORF1ab/nsp3225A225VgCagTa33B.1.3560.005181
ORF1ab/nsp3225A225VgCagTa33B.1.36.210.006479
ORF1ab/nsp3225A225VgCagTa33B.1.4270.000151
ORF1ab/nsp3225A225VgCagTa33B.1.6370.000219
ORF1ab/nsp3225A225VgCagTa33C.200.230769
ORF1ab/nsp3225A225VgCagTa33D.20.000225
ORF1ab/nsp3225A225VgCagTa33P.20.00056
ORF1ab/nsp3225A225VgCagTa33P.30.004785
ORF1ab/nsp3225A225VgCagTa22AD.20.000438
ORF1ab/nsp3225A225VgCagTa22AY.1080.002205
ORF1ab/nsp3225A225VgCagTa22AY.1160.000574
ORF1ab/nsp3225A225VgCagTa22AY.1210.000271
ORF1ab/nsp3225A225VgCagTa22AY.160.000759
ORF1ab/nsp3225A225VgCagTa22AY.230.000139
ORF1ab/nsp3225A225VgCagTa22AY.360.000296
ORF1ab/nsp3225A225VgCagTa22AY.39.10.000079
ORF1ab/nsp3225A225VgCagTa22AY.4.10.001475
ORF1ab/nsp3225A225VgCagTa22AY.420.00008
ORF1ab/nsp3225A225VgCagTa22AY.580.001815
ORF1ab/nsp3225A225VgCagTa22AY.90.000135
ORF1ab/nsp3225A225VgCagTa22AY.980.000158
ORF1ab/nsp3225A225VgCagTa22B0.000256
ORF1ab/nsp3225A225VgCagTa22B.1.1.2160.001781
ORF1ab/nsp3225A225VgCagTa22B.1.1.2170.007273
ORF1ab/nsp3225A225VgCagTa22B.1.1.3060.000877
ORF1ab/nsp3225A225VgCagTa22B.1.1.3790.0625
ORF1ab/nsp3225A225VgCagTa22B.1.1390.001466
ORF1ab/nsp3225A225VgCagTa22B.1.177.600.000437
ORF1ab/nsp3225A225VgCagTa22B.1.351.30.001753
ORF1ab/nsp3225A225VgCagTa22B.1.3690.00057
ORF1ab/nsp3225A225VgCagTa22B.1.416.10.003125
ORF1ab/nsp3225A225VgCagTa22B.1.5180.023529
ORF1ab/nsp3225A225VgCagTa22B.1.5760.001813
ORF1ab/nsp3225A225VgCagTa22B.1.6180.008065
ORF1ab/nsp3225A225VgCagTa22P.1.170.000324
ORF1ab/nsp3225A225VgCagTa11A.10.000282
ORF1ab/nsp3225A225VgCagTa11A.2.40.003367
ORF1ab/nsp3225A225VgCagTa11A.30.002096
ORF1ab/nsp3225A225VgCagTa11AP.10.001502
ORF1ab/nsp3225A225VgCagTa11AY.10.000396
ORF1ab/nsp3225A225VgCagTa11AY.1070.000466
ORF1ab/nsp3225A225VgCagTa11AY.1090.00074
ORF1ab/nsp3225A225VgCagTa11AY.1110.000183
ORF1ab/nsp3225A225VgCagTa11AY.1190.000035
ORF1ab/nsp3225A225VgCagTa11AY.140.000088
ORF1ab/nsp3225A225VgCagTa11AY.29.10.000221
ORF1ab/nsp3225A225VgCagTa11AY.340.000097
ORF1ab/nsp3225A225VgCagTa11AY.34.10.00051
ORF1ab/nsp3225A225VgCagTa11AY.4.2.10.000149
ORF1ab/nsp3225A225VgCagTa11AY.4.40.000409
ORF1ab/nsp3225A225VgCagTa11AY.46.40.000165
ORF1ab/nsp3225A225VgCagTa11AY.530.000288
ORF1ab/nsp3225A225VgCagTa11AY.540.000095
ORF1ab/nsp3225A225VgCagTa11AY.570.000656
ORF1ab/nsp3225A225VgCagTa11AY.590.00053
ORF1ab/nsp3225A225VgCagTa11AY.620.000436
ORF1ab/nsp3225A225VgCagTa11AY.690.000187
ORF1ab/nsp3225A225VgCagTa11AY.70.000196
ORF1ab/nsp3225A225VgCagTa11AY.75.10.00018
ORF1ab/nsp3225A225VgCagTa11AY.790.001211
ORF1ab/nsp3225A225VgCagTa11AY.880.000884
ORF1ab/nsp3225A225VgCagTa11B.1.1.1530.001095
ORF1ab/nsp3225A225VgCagTa11B.1.1.2840.000107
ORF1ab/nsp3225A225VgCagTa11B.1.1.3010.001179
ORF1ab/nsp3225A225VgCagTa11B.1.1.3290.003846
ORF1ab/nsp3225A225VgCagTa11B.1.1.3480.000796
ORF1ab/nsp3225A225VgCagTa11B.1.1.3720.000689
ORF1ab/nsp3225A225VgCagTa11B.1.1.4090.002833
ORF1ab/nsp3225A225VgCagTa11B.1.1.4130.006897
ORF1ab/nsp3225A225VgCagTa11B.1.1.5170.006803
ORF1ab/nsp3225A225VgCagTa11B.1.1.5190.00004
ORF1ab/nsp3225A225VgCagTa11B.1.120.008
ORF1ab/nsp3225A225VgCagTa11B.1.1570.002985
ORF1ab/nsp3225A225VgCagTa11B.1.1590.012195
ORF1ab/nsp3225A225VgCagTa11B.1.177.240.001295
ORF1ab/nsp3225A225VgCagTa11B.1.177.360.016129
ORF1ab/nsp3225A225VgCagTa11B.1.177.460.000918
ORF1ab/nsp3225A225VgCagTa11B.1.177.60.000977
ORF1ab/nsp3225A225VgCagTa11B.1.177.70.000165
ORF1ab/nsp3225A225VgCagTa11B.1.221.30.000833
ORF1ab/nsp3225A225VgCagTa11B.1.2600.003344
ORF1ab/nsp3225A225VgCagTa11B.1.351.20.000303
ORF1ab/nsp3225A225VgCagTa11B.1.360.000146
ORF1ab/nsp3225A225VgCagTa11B.1.36.180.00042
ORF1ab/nsp3225A225VgCagTa11B.1.36.290.000517
ORF1ab/nsp3225A225VgCagTa11B.1.3630.012987
ORF1ab/nsp3225A225VgCagTa11B.1.3670.000792
ORF1ab/nsp3225A225VgCagTa11B.1.4200.010417
ORF1ab/nsp3225A225VgCagTa11B.1.438.10.000107
ORF1ab/nsp3225A225VgCagTa11B.1.4390.005917
ORF1ab/nsp3225A225VgCagTa11B.1.5170.000427
ORF1ab/nsp3225A225VgCagTa11B.1.5210.004975
ORF1ab/nsp3225A225VgCagTa11B.1.5250.000113
ORF1ab/nsp3225A225VgCagTa11B.1.5610.000397
ORF1ab/nsp3225A225VgCagTa11B.1.564.10.001577
ORF1ab/nsp3225A225VgCagTa11B.1.5700.002941
ORF1ab/nsp3225A225VgCagTa11B.1.5770.000687
ORF1ab/nsp3225A225VgCagTa11B.1.5820.000491
ORF1ab/nsp3225A225VgCagTa11B.1.617.10.000129
ORF1ab/nsp3225A225VgCagTa11B.1.6200.000946
ORF1ab/nsp3225A225VgCagTa11B.1.6340.003425
ORF1ab/nsp3225A225VgCagTa11B.40.002208
ORF1ab/nsp3225A225VgCagTa11B.4.50.011905
ORF1ab/nsp3225A225VgCagTa11C.1.20.004255
ORF1ab/nsp3225A225VgCagTa11N.90.005952
ORF1ab/nsp3225A225VgCagTa11P.1.130.000898
ORF1ab/nsp3225A225VgCagTa11P.1.140.000048
ORF1ab/nsp3225A225VgCagTa11Q.30.000145
ORF1ab/nsp3225A225VgCagTa11R.10.00009

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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