CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = A1527G

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31527A1527GA2345GnonsyngCagGa1280.6666677298-7300
ORF1ab/nsp31527A1527GA2345GnonsyngCAgGC1230.257298-7300
ORF1ab/nsp31527A1527GA2345GnonsyngCAgGT1210.08333337298-7300

Details of the mutation A1527G within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31527A1527GgCagGa812All0.000002
ORF1ab/nsp31527A1527GgCAgGC312All0.000001
ORF1ab/nsp31527A1527GgCAgGT112All0
ORF1ab/nsp31527A1527GgCagGa230.111111
ORF1ab/nsp31527A1527GgCAgGC130.055556
ORF1ab/nsp31527A1527GgCagGa23B.10.000018
ORF1ab/nsp31527A1527GgCAgGC13B.10.000009
ORF1ab/nsp31527A1527GgCagGa12K.10.02381
ORF1ab/nsp31527A1527GgCAgGC12K.10.02381
ORF1ab/nsp31527A1527GgCagGa11AY.1070.000466
ORF1ab/nsp31527A1527GgCagGa11AY.590.00053
ORF1ab/nsp31527A1527GgCagGa11B.1.617.20.000004
ORF1ab/nsp31527A1527GgCAgGT11B.4.40.018868

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.