CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = A1526V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31526A1526VA2344VnonsyngCtgTt176217610.9994327295-7297
ORF1ab/nsp31526A1526VA2344VnonsyngCTgTA176210.0005675377295-7297

Details of the mutation A1526V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31526A1526VgCtgTt17611762All0.000337
ORF1ab/nsp31526A1526VgCTgTA11762All0
ORF1ab/nsp31526A1526VgCtgTt421421AY.30.004187
ORF1ab/nsp31526A1526VgCtgTt299299B.1.617.30.892537
ORF1ab/nsp31526A1526VgCtgTt105105B.1.1.70.000094
ORF1ab/nsp31526A1526VgCtgTt6969B.1.2340.009104
ORF1ab/nsp31526A1526VgCtgTt6565B.1.243.20.942029
ORF1ab/nsp31526A1526VgCtgTt6464B.1.617.20.000241
ORF1ab/nsp31526A1526VgCtgTt5959AY.330.00394
ORF1ab/nsp31526A1526VgCtgTt5757B.1.1.5190.002264
ORF1ab/nsp31526A1526VgCtgTt4141AY.40.000064
ORF1ab/nsp31526A1526VgCtgTt3939B.1.10.000707
ORF1ab/nsp31526A1526VgCtgTt3939B.1.1.3730.928571
ORF1ab/nsp31526A1526VgCtgTt3737B.10.000339
ORF1ab/nsp31526A1526VgCtgTt3434AY.1020.000901
ORF1ab/nsp31526A1526VgCtgTt2626AY.430.000115
ORF1ab/nsp31526A1526VgCtgTt2626B.1.214.20.015588
ORF1ab/nsp31526A1526VgCtgTt2020B.1.5960.001743
ORF1ab/nsp31526A1526VgCtgTt1616B.1.2210.001137
ORF1ab/nsp31526A1526VgCtgTt1515AY.200.000583
ORF1ab/nsp31526A1526VgCtgTt1414B.1.1650.166667
ORF1ab/nsp31526A1526VgCtgTt1313B.1.177.600.00284
ORF1ab/nsp31526A1526VgCtgTt1212B.1.5260.000282
ORF1ab/nsp31526A1526VgCtgTt1111AY.1210.001488
ORF1ab/nsp31526A1526VgCtgTt1111B.1.1.4220.5
ORF1ab/nsp31526A1526VgCtgTt1111B.1.20.000097
ORF1ab/nsp31526A1526VgCtgTt1010AY.140.00088
ORF1ab/nsp31526A1526VgCtgTt1010AY.440.000061
ORF1ab/nsp31526A1526VgCtgTt1010B.1.6390.217391
ORF1ab/nsp31526A1526VgCtgTt99AY.260.000255
ORF1ab/nsp31526A1526VgCtgTt99AY.390.000222
ORF1ab/nsp31526A1526VgCtgTt99AY.60.00037
ORF1ab/nsp31526A1526VgCtgTt99B.1.1770.000119
ORF1ab/nsp31526A1526VgCtgTt77AY.930.001912
ORF1ab/nsp31526A1526VgCtgTt66AY.470.000187
ORF1ab/nsp31526A1526VgCtgTt66B.1.5950.001566
ORF1ab/nsp31526A1526VgCtgTt66C.370.000696
ORF1ab/nsp31526A1526VgCtgTt55AY.1030.000031
ORF1ab/nsp31526A1526VgCtgTt55AY.230.000349
ORF1ab/nsp31526A1526VgCtgTt55AY.250.00003
ORF1ab/nsp31526A1526VgCtgTt55AY.610.000524
ORF1ab/nsp31526A1526VgCtgTt55AY.9.20.000184
ORF1ab/nsp31526A1526VgCtgTt55P.10.000079
ORF1ab/nsp31526A1526VgCtgTt44AY.1170.000338
ORF1ab/nsp31526A1526VgCtgTt44AY.1190.000141
ORF1ab/nsp31526A1526VgCtgTt44AY.1200.000149
ORF1ab/nsp31526A1526VgCtgTt44AY.320.00213
ORF1ab/nsp31526A1526VgCtgTt44B.1.1.1920.009238
ORF1ab/nsp31526A1526VgCtgTt44B.1.2400.000862
ORF1ab/nsp31526A1526VgCtgTt44B.1.5510.005161
ORF1ab/nsp31526A1526VgCtgTt33AY.750.000168
ORF1ab/nsp31526A1526VgCtgTt33B.1.1.2140.000166
ORF1ab/nsp31526A1526VgCtgTt33B.1.1.3060.001315
ORF1ab/nsp31526A1526VgCtgTt33B.1.36.290.001552
ORF1ab/nsp31526A1526VgCtgTt33D.20.000225
ORF1ab/nsp31526A1526VgCTgTA120.055556
ORF1ab/nsp31526A1526VgCtgTt120.055556
ORF1ab/nsp31526A1526VgCtgTt22AY.1000.000092
ORF1ab/nsp31526A1526VgCtgTt22AY.1180.000125
ORF1ab/nsp31526A1526VgCtgTt22AY.280.003781
ORF1ab/nsp31526A1526VgCtgTt22AY.290.000032
ORF1ab/nsp31526A1526VgCtgTt22AY.39.10.000079
ORF1ab/nsp31526A1526VgCtgTt22AY.46.60.000144
ORF1ab/nsp31526A1526VgCtgTt22AY.5.30.000675
ORF1ab/nsp31526A1526VgCtgTt22AY.590.001059
ORF1ab/nsp31526A1526VgCtgTt22AY.720.002721
ORF1ab/nsp31526A1526VgCtgTt22AY.840.000875
ORF1ab/nsp31526A1526VgCtgTt22B.1.1.2530.005013
ORF1ab/nsp31526A1526VgCtgTt22B.1.1.330.000842
ORF1ab/nsp31526A1526VgCtgTt22B.1.1.3980.006452
ORF1ab/nsp31526A1526VgCtgTt22B.1.1.4340.000697
ORF1ab/nsp31526A1526VgCtgTt22B.1.1600.000062
ORF1ab/nsp31526A1526VgCtgTt22B.1.3510.000059
ORF1ab/nsp31526A1526VgCtgTt22B.1.36.190.018519
ORF1ab/nsp31526A1526VgCtgTt22B.1.428.30.025641
ORF1ab/nsp31526A1526VgCtgTt22B.1.466.20.000782
ORF1ab/nsp31526A1526VgCtgTt22B.1.617.10.000258
ORF1ab/nsp31526A1526VgCtgTt22C.140.008658
ORF1ab/nsp31526A1526VgCtgTt22P.1.10.000635
ORF1ab/nsp31526A1526VgCtgTt22R.10.00018
ORF1ab/nsp31526A1526VgCtgTt11A.20.000662
ORF1ab/nsp31526A1526VgCtgTt11AY.1070.000466
ORF1ab/nsp31526A1526VgCtgTt11AY.120.10.000321
ORF1ab/nsp31526A1526VgCtgTt11AY.16.10.00047
ORF1ab/nsp31526A1526VgCtgTt11AY.340.000097
ORF1ab/nsp31526A1526VgCtgTt11AY.380.000499
ORF1ab/nsp31526A1526VgCtgTt11AY.4.30.000842
ORF1ab/nsp31526A1526VgCtgTt11AY.450.000122
ORF1ab/nsp31526A1526VgCtgTt11AY.46.10.001027
ORF1ab/nsp31526A1526VgCtgTt11AY.5.20.002463
ORF1ab/nsp31526A1526VgCtgTt11AY.540.000095
ORF1ab/nsp31526A1526VgCtgTt11AY.550.000917
ORF1ab/nsp31526A1526VgCtgTt11AY.580.000907
ORF1ab/nsp31526A1526VgCtgTt11AY.740.000116
ORF1ab/nsp31526A1526VgCtgTt11AY.920.000287
ORF1ab/nsp31526A1526VgCtgTt11AY.980.000079
ORF1ab/nsp31526A1526VgCtgTt11AY.98.10.000048
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.10.000327
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.2740.005051
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.3850.004464
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.3970.002252
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.4090.002833
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.4140.142857
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.4520.111111
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.4850.016667
ORF1ab/nsp31526A1526VgCtgTt11B.1.1.630.000386
ORF1ab/nsp31526A1526VgCtgTt11B.1.1340.005464
ORF1ab/nsp31526A1526VgCtgTt11B.1.1390.000733
ORF1ab/nsp31526A1526VgCtgTt11B.1.160.260.002421
ORF1ab/nsp31526A1526VgCtgTt11B.1.1610.017241
ORF1ab/nsp31526A1526VgCtgTt11B.1.2470.014925
ORF1ab/nsp31526A1526VgCtgTt11B.1.258.160.001637
ORF1ab/nsp31526A1526VgCtgTt11B.1.3110.000275
ORF1ab/nsp31526A1526VgCtgTt11B.1.360.000146
ORF1ab/nsp31526A1526VgCtgTt11B.1.36.310.001751
ORF1ab/nsp31526A1526VgCtgTt11B.1.3690.000285
ORF1ab/nsp31526A1526VgCtgTt11B.1.4270.00005
ORF1ab/nsp31526A1526VgCtgTt11B.1.4590.004082
ORF1ab/nsp31526A1526VgCtgTt11B.1.4660.023256
ORF1ab/nsp31526A1526VgCtgTt11B.1.4740.001901
ORF1ab/nsp31526A1526VgCtgTt11B.1.5610.000397
ORF1ab/nsp31526A1526VgCtgTt11B.1.5700.002941
ORF1ab/nsp31526A1526VgCtgTt11B.1.6200.000946
ORF1ab/nsp31526A1526VgCtgTt11B.30.000831
ORF1ab/nsp31526A1526VgCtgTt11C.1.10.076923
ORF1ab/nsp31526A1526VgCtgTt11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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