CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = A1431A

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31431A1431AA2249AsyngcTgcC3041480.4868427010-7012
ORF1ab/nsp31431A1431AA2249AsyngcTgcA304810.2664477010-7012
ORF1ab/nsp31431A1431AA2249AsyngcTgcG304750.2467117010-7012

Details of the mutation A1431A within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31431A1431AgcTgcC148304All0.000028
ORF1ab/nsp31431A1431AgcTgcA81304All0.000015
ORF1ab/nsp31431A1431AgcTgcG75304All0.000014
ORF1ab/nsp31431A1431AgcTgcG5152C.370.005919
ORF1ab/nsp31431A1431AgcTgcC152C.370.000116
ORF1ab/nsp31431A1431AgcTgcC4447B.1.1.70.000039
ORF1ab/nsp31431A1431AgcTgcG347B.1.1.70.000003
ORF1ab/nsp31431A1431AgcTgcA3737B.1.1.621
ORF1ab/nsp31431A1431AgcTgcA1322B.1.10.000236
ORF1ab/nsp31431A1431AgcTgcC922B.1.10.000163
ORF1ab/nsp31431A1431AgcTgcA1016B.1.20.000088
ORF1ab/nsp31431A1431AgcTgcC616B.1.20.000053
ORF1ab/nsp31431A1431AgcTgcC1414P.10.000221
ORF1ab/nsp31431A1431AgcTgcC510B.10.000046
ORF1ab/nsp31431A1431AgcTgcA510B.10.000046
ORF1ab/nsp31431A1431AgcTgcC99B.1.1.3160.008326
ORF1ab/nsp31431A1431AgcTgcA99B.1.1.3830.5625
ORF1ab/nsp31431A1431AgcTgcC99B.1.617.20.000034
ORF1ab/nsp31431A1431AgcTgcC88AY.40.000012
ORF1ab/nsp31431A1431AgcTgcC45AY.430.000018
ORF1ab/nsp31431A1431AgcTgcG15AY.430.000004
ORF1ab/nsp31431A1431AgcTgcC34AY.390.000074
ORF1ab/nsp31431A1431AgcTgcG14AY.390.000025
ORF1ab/nsp31431A1431AgcTgcC34AY.440.000018
ORF1ab/nsp31431A1431AgcTgcG14AY.440.000006
ORF1ab/nsp31431A1431AgcTgcG44AY.46.50.000794
ORF1ab/nsp31431A1431AgcTgcC34B.1.1770.00004
ORF1ab/nsp31431A1431AgcTgcG14B.1.1770.000013
ORF1ab/nsp31431A1431AgcTgcC33AY.250.000018
ORF1ab/nsp31431A1431AgcTgcA120.055556
ORF1ab/nsp31431A1431AgcTgcC120.055556
ORF1ab/nsp31431A1431AgcTgcA12AY.1030.000006
ORF1ab/nsp31431A1431AgcTgcC12AY.1030.000006
ORF1ab/nsp31431A1431AgcTgcC22AY.1210.000271
ORF1ab/nsp31431A1431AgcTgcC22AY.460.000208
ORF1ab/nsp31431A1431AgcTgcG22B.1.1890.008584
ORF1ab/nsp31431A1431AgcTgcG22B.1.466.20.000782
ORF1ab/nsp31431A1431AgcTgcG11A.2.40.003367
ORF1ab/nsp31431A1431AgcTgcG11AY.1020.000027
ORF1ab/nsp31431A1431AgcTgcC11AY.1080.001103
ORF1ab/nsp31431A1431AgcTgcC11AY.1190.000035
ORF1ab/nsp31431A1431AgcTgcG11AY.160.00038
ORF1ab/nsp31431A1431AgcTgcC11AY.230.00007
ORF1ab/nsp31431A1431AgcTgcC11AY.3.10.000085
ORF1ab/nsp31431A1431AgcTgcC11AY.330.000067
ORF1ab/nsp31431A1431AgcTgcC11AY.420.00004
ORF1ab/nsp31431A1431AgcTgcA11AY.50.000021
ORF1ab/nsp31431A1431AgcTgcC11AY.670.000464
ORF1ab/nsp31431A1431AgcTgcA11AY.700.000209
ORF1ab/nsp31431A1431AgcTgcG11AY.80.000606
ORF1ab/nsp31431A1431AgcTgcC11AY.850.000427
ORF1ab/nsp31431A1431AgcTgcC11AY.9.10.000084
ORF1ab/nsp31431A1431AgcTgcG11AY.980.000079
ORF1ab/nsp31431A1431AgcTgcC11B.1.1.2070.001182
ORF1ab/nsp31431A1431AgcTgcA11B.1.1.250.000569
ORF1ab/nsp31431A1431AgcTgcC11B.1.1.2690.001353
ORF1ab/nsp31431A1431AgcTgcG11B.1.1.3690.000446
ORF1ab/nsp31431A1431AgcTgcC11B.1.1.4420.018519
ORF1ab/nsp31431A1431AgcTgcC11B.1.1.5190.00004
ORF1ab/nsp31431A1431AgcTgcC11B.1.1530.018868
ORF1ab/nsp31431A1431AgcTgcG11B.1.1600.000031
ORF1ab/nsp31431A1431AgcTgcA11B.1.177.350.000691
ORF1ab/nsp31431A1431AgcTgcG11B.1.177.540.000606
ORF1ab/nsp31431A1431AgcTgcC11B.1.2430.00007
ORF1ab/nsp31431A1431AgcTgcC11B.1.3510.00003
ORF1ab/nsp31431A1431AgcTgcC11B.1.4040.001302
ORF1ab/nsp31431A1431AgcTgcA11B.1.4270.00005
ORF1ab/nsp31431A1431AgcTgcC11B.1.4290.000024
ORF1ab/nsp31431A1431AgcTgcC11B.1.5260.000024
ORF1ab/nsp31431A1431AgcTgcC11B.1.5960.000087
ORF1ab/nsp31431A1431AgcTgcG11P.1.10.000318
ORF1ab/nsp31431A1431AgcTgcC11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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