CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : Mut = A1381V

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31381A1381VA2199VnonsyngCagTa8498400.9893996860-6862
ORF1ab/nsp31381A1381VA2199VnonsyngCAgTT84980.009422856860-6862
ORF1ab/nsp31381A1381VA2199VnonsyngCAgTG84910.001177866860-6862

Details of the mutation A1381V within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31381A1381VgCagTa840849All0.000161
ORF1ab/nsp31381A1381VgCAgTT8849All0.000002
ORF1ab/nsp31381A1381VgCAgTG1849All0
ORF1ab/nsp31381A1381VgCagTa146153B.1.1.70.000131
ORF1ab/nsp31381A1381VgCAgTT7153B.1.1.70.000006
ORF1ab/nsp31381A1381VgCagTa8080AY.420.003218
ORF1ab/nsp31381A1381VgCagTa7373B.1.1.3290.280769
ORF1ab/nsp31381A1381VgCagTa6868B.1.1.100.075808
ORF1ab/nsp31381A1381VgCagTa6767AY.30.000666
ORF1ab/nsp31381A1381VgCagTa3131AY.40.000048
ORF1ab/nsp31381A1381VgCagTa2929B.1.177.600.006335
ORF1ab/nsp31381A1381VgCagTa2323AY.440.00014
ORF1ab/nsp31381A1381VgCagTa2222AY.1110.004029
ORF1ab/nsp31381A1381VgCagTa1919AY.1030.000118
ORF1ab/nsp31381A1381VgCagTa1818L.40.9
ORF1ab/nsp31381A1381VgCagTa1717AY.250.000102
ORF1ab/nsp31381A1381VgCagTa1616P.10.000252
ORF1ab/nsp31381A1381VgCagTa1515B.10.000137
ORF1ab/nsp31381A1381VgCagTa1515B.1.617.20.000056
ORF1ab/nsp31381A1381VgCagTa1414AY.430.000062
ORF1ab/nsp31381A1381VgCagTa1414B.1.20.000123
ORF1ab/nsp31381A1381VgCagTa1414B.1.2430.000974
ORF1ab/nsp31381A1381VgCagTa1213B.1.10.000218
ORF1ab/nsp31381A1381VgCAgTT113B.1.10.000018
ORF1ab/nsp31381A1381VgCagTa1010AY.200.000389
ORF1ab/nsp31381A1381VgCagTa99P.1.150.002091
ORF1ab/nsp31381A1381VgCagTa88AY.850.003417
ORF1ab/nsp31381A1381VgCagTa88AY.99.20.000737
ORF1ab/nsp31381A1381VgCagTa77B.1.970.179487
ORF1ab/nsp31381A1381VgCagTa55AY.9.20.000184
ORF1ab/nsp31381A1381VgCagTa55B.1.1.5190.000199
ORF1ab/nsp31381A1381VgCagTa55B.1.5260.000118
ORF1ab/nsp31381A1381VgCagTa44AY.1020.000106
ORF1ab/nsp31381A1381VgCagTa44AY.1170.000338
ORF1ab/nsp31381A1381VgCagTa44B.1.1.10.001307
ORF1ab/nsp31381A1381VgCagTa44B.1.1.4320.005063
ORF1ab/nsp31381A1381VgCagTa44B.1.5250.000453
ORF1ab/nsp31381A1381VgCagTa33B.1.2210.000213
ORF1ab/nsp31381A1381VgCagTa33C.370.000348
ORF1ab/nsp31381A1381VgCagTa33D.20.000225
ORF1ab/nsp31381A1381VgCagTa220.111111
ORF1ab/nsp31381A1381VgCagTa22AY.1000.000092
ORF1ab/nsp31381A1381VgCagTa22AY.1180.000125
ORF1ab/nsp31381A1381VgCagTa22AY.1190.000071
ORF1ab/nsp31381A1381VgCagTa22AY.1200.000074
ORF1ab/nsp31381A1381VgCagTa22AY.190.002281
ORF1ab/nsp31381A1381VgCagTa22AY.270.000129
ORF1ab/nsp31381A1381VgCagTa22AY.390.000049
ORF1ab/nsp31381A1381VgCagTa22B.1.1.2140.000111
ORF1ab/nsp31381A1381VgCagTa22B.1.2410.001623
ORF1ab/nsp31381A1381VgCagTa22B.1.2580.000133
ORF1ab/nsp31381A1381VgCagTa22B.1.258.170.000208
ORF1ab/nsp31381A1381VgCagTa22B.1.5960.000174
ORF1ab/nsp31381A1381VgCagTa11A0.000387
ORF1ab/nsp31381A1381VgCagTa11AD.20.000219
ORF1ab/nsp31381A1381VgCagTa11AY.1070.000466
ORF1ab/nsp31381A1381VgCagTa11AY.1090.00074
ORF1ab/nsp31381A1381VgCagTa11AY.230.00007
ORF1ab/nsp31381A1381VgCagTa11AY.290.000016
ORF1ab/nsp31381A1381VgCagTa11AY.320.000532
ORF1ab/nsp31381A1381VgCagTa11AY.340.000097
ORF1ab/nsp31381A1381VgCagTa11AY.4.20.000022
ORF1ab/nsp31381A1381VgCagTa11AY.470.000031
ORF1ab/nsp31381A1381VgCagTa11AY.480.000465
ORF1ab/nsp31381A1381VgCagTa11AY.50.000021
ORF1ab/nsp31381A1381VgCagTa11AY.740.000116
ORF1ab/nsp31381A1381VgCagTa11AY.790.001211
ORF1ab/nsp31381A1381VgCagTa11AY.840.000437
ORF1ab/nsp31381A1381VgCagTa11AY.90.000068
ORF1ab/nsp31381A1381VgCagTa11B.1.1.280.000311
ORF1ab/nsp31381A1381VgCagTa11B.1.1.2940.001266
ORF1ab/nsp31381A1381VgCagTa11B.1.1.3810.04
ORF1ab/nsp31381A1381VgCagTa11B.1.1.390.00051
ORF1ab/nsp31381A1381VgCagTa11B.1.2350.002519
ORF1ab/nsp31381A1381VgCagTa11B.1.3490.000715
ORF1ab/nsp31381A1381VgCagTa11B.1.3510.00003
ORF1ab/nsp31381A1381VgCagTa11B.1.3960.000706
ORF1ab/nsp31381A1381VgCagTa11B.1.4270.00005
ORF1ab/nsp31381A1381VgCagTa11B.1.4290.000024
ORF1ab/nsp31381A1381VgCagTa11B.1.466.20.000391
ORF1ab/nsp31381A1381VgCagTa11B.1.4690.00361
ORF1ab/nsp31381A1381VgCagTa11B.1.5880.00091
ORF1ab/nsp31381A1381VgCagTa11B.1.6120.002653
ORF1ab/nsp31381A1381VgCAgTG11B.1.617.10.000129
ORF1ab/nsp31381A1381VgCagTa11B.1.621.10.000506
ORF1ab/nsp31381A1381VgCagTa11C.360.000911
ORF1ab/nsp31381A1381VgCagTa11P.1.130.000898
ORF1ab/nsp31381A1381VgCagTa11Q.10.000126
ORF1ab/nsp31381A1381VgCagTa11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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