CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 977

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3977K977QK1795QnonsynAaaCaa1150031150020.9999915648-5650
ORF1ab/nsp3977K977QK1795QnonsynAaACaG11500310.000008695435648-5650
ORF1ab/nsp3977K977KK1795KsynaaAaaG1060106015648-5650
ORF1ab/nsp3977K977TK1795TnonsynaAaaCa53353315648-5650
ORF1ab/nsp3977K977RK1795RnonsynaAaaGa66620.9393945648-5650
ORF1ab/nsp3977K977RK1795RnonsynaAAaGG6640.06060615648-5650
ORF1ab/nsp3977K977EK1795EnonsynAaaGaa383815648-5650
ORF1ab/nsp3977K977NK1795NnonsynaaAaaC31160.5161295648-5650
ORF1ab/nsp3977K977NK1795NnonsynaaAaaT31150.4838715648-5650
ORF1ab/nsp3977K977delK1795deldelAAA---272715648-5650
ORF1ab/nsp3977K977IK1795InonsynaAaaTa212115648-5650
ORF1ab/nsp3977K977CK1795CnonsynAAATGC2215648-5650
ORF1ab/nsp3977K977DK1795DnonsynAaAGaC1115648-5650

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3977K977QAaaCaa115002115003All0.021995
ORF1ab/nsp3977K977QAaACaG1115003All0
ORF1ab/nsp3977K977QAaaCaa6318763187P.10.995447
ORF1ab/nsp3977K977QAaaCaa2081220812P.1.140.994837
ORF1ab/nsp3977K977QAaaCaa61676167P.1.170.997574
ORF1ab/nsp3977K977QAaaCaa42754275P.1.150.993262
ORF1ab/nsp3977K977QAaaCaa37023702P.1.100.997575
ORF1ab/nsp3977K977QAaaCaa31233123P.1.70.997126
ORF1ab/nsp3977K977QAaaCaa30143014P.1.10.957433
ORF1ab/nsp3977K977QAaaCaa26312631P.1.160.984287
ORF1ab/nsp3977K977QAaaCaa19591959P.1.120.948209
ORF1ab/nsp3977K977QAaaCaa11001100P.1.130.98832
ORF1ab/nsp3977K977KaaAaaG10601060All0.000203
ORF1ab/nsp3977K977QAaaCaa10281028P.1.17.10.899388
ORF1ab/nsp3977K977QAaaCaa10241024P.1.41
ORF1ab/nsp3977K977QAaaCaa862862P.1.20.996532
ORF1ab/nsp3977K977TaAaaCa533533All0.000102
ORF1ab/nsp3977K977QAaaCaa514514P.1.61
ORF1ab/nsp3977K977TaAaaCa435435B.1.20.00383
ORF1ab/nsp3977K977KaaAaaG388388AY.430.001719
ORF1ab/nsp3977K977KaaAaaG354354B.1.4290.008329
ORF1ab/nsp3977K977QAaaCaa209209P.1.81
ORF1ab/nsp3977K977QAaaCaa208208P.1.91
ORF1ab/nsp3977K977QAaaCaa188188B.1.6300.984293
ORF1ab/nsp3977K977QAaaCaa152152B.1.1.70.000136
ORF1ab/nsp3977K977QAaaCaa121122B.10.001108
ORF1ab/nsp3977K977QAaACaG1122B.10.000009
ORF1ab/nsp3977K977QAaaCaa114114P.1.10.10.926829
ORF1ab/nsp3977K977QAaaCaa9898P.1.111
ORF1ab/nsp3977K977QAaaCaa8282B.1.10.001488
ORF1ab/nsp3977K977TaAaaCa8080B.1.5960.006971
ORF1ab/nsp3977K977QAaaCaa7272AY.9.20.002645
ORF1ab/nsp3977K977RaAaaGa6266All0.000012
ORF1ab/nsp3977K977RaAAaGG466All0.000001
ORF1ab/nsp3977K977KaaAaaG5454B.1.1.70.000048
ORF1ab/nsp3977K977QAaaCaa4545B.1.2410.036526
ORF1ab/nsp3977K977KaaAaaG4141AY.40.000064
ORF1ab/nsp3977K977KaaAaaG4141AY.50.000847
ORF1ab/nsp3977K977EAaaGaa3838All0.000007
ORF1ab/nsp3977K977NaaAaaC1631All0.000003
ORF1ab/nsp3977K977NaaAaaT1531All0.000003
ORF1ab/nsp3977K977QAaaCaa2929C.370.003366
ORF1ab/nsp3977K977QAaaCaa2929P.1.31
ORF1ab/nsp3977K977RaAaaGa2828B.1.1.70.000025
ORF1ab/nsp3977K977delAAA---2727All0.000005
ORF1ab/nsp3977K977QAaaCaa2424P.1.10.21
ORF1ab/nsp3977K977KaaAaaG2323A.2.40.077441
ORF1ab/nsp3977K977IaAaaTa2121All0.000004
ORF1ab/nsp3977K977QAaaCaa2121B.1.1.5280.100962
ORF1ab/nsp3977K977KaaAaaG1919B.1.617.20.000072
ORF1ab/nsp3977K977IaAaaTa1717B.1.1.70.000015
ORF1ab/nsp3977K977EAaaGaa1616B.1.1.70.000014
ORF1ab/nsp3977K977QAaaCaa1616B.1.617.20.00006
ORF1ab/nsp3977K977KaaAaaG1313AY.260.000368
ORF1ab/nsp3977K977KaaAaaG1313B.1.1420.037681
ORF1ab/nsp3977K977QAaaCaa1313P.1.51
ORF1ab/nsp3977K977RaAaaGa1212AY.5.30.004049
ORF1ab/nsp3977K977KaaAaaG1212AY.860.009959
ORF1ab/nsp3977K977delAAA---1212B.1.1.70.000011
ORF1ab/nsp3977K977KaaAaaG1111AY.30.000109
ORF1ab/nsp3977K977QAaaCaa1010A.2.50.00499
ORF1ab/nsp3977K977QAaaCaa99B.1.1.280.002801
ORF1ab/nsp3977K977QAaaCaa88AY.260.000226
ORF1ab/nsp3977K977QAaaCaa88C.37.10.020942
ORF1ab/nsp3977K977KaaAaaG77AY.1020.000186
ORF1ab/nsp3977K977QAaaCaa77AY.430.000031
ORF1ab/nsp3977K977KaaAaaG77B.10.000064
ORF1ab/nsp3977K977TaAaaCa66AY.1130.000854
ORF1ab/nsp3977K977QAaaCaa66AY.250.000036
ORF1ab/nsp3977K977KaaAaaG66AY.390.000148
ORF1ab/nsp3977K977QAaaCaa66AY.40.000009
ORF1ab/nsp3977K977EAaaGaa66AY.430.000027
ORF1ab/nsp3977K977QAaaCaa66AY.440.000037
ORF1ab/nsp3977K977KaaAaaG66AY.440.000037
ORF1ab/nsp3977K977KaaAaaG66AY.470.000187
ORF1ab/nsp3977K977QAaaCaa66B.1.1770.000079
ORF1ab/nsp3977K977QAaaCaa66B.1.4160.007614
ORF1ab/nsp3977K977NaaAaaC66B.1.5750.00182
ORF1ab/nsp3977K977KaaAaaG66B.1.6270.012121
ORF1ab/nsp3977K977NaaAaaT55B.1.1.70.000004
ORF1ab/nsp3977K977QAaaCaa55B.1.4290.000118
ORF1ab/nsp3977K977QAaaCaa55B.1.5260.000118
ORF1ab/nsp3977K977QAaaCaa55B.1.6210.000443
ORF1ab/nsp3977K977TaAaaCa44AY.440.000024
ORF1ab/nsp3977K977QAaaCaa44B0.000511
ORF1ab/nsp3977K977KaaAaaG44B.1.10.000073
ORF1ab/nsp3977K977QAaaCaa44B.1.1.5070.034783
ORF1ab/nsp3977K977RaAaaGa44B.1.2210.000284
ORF1ab/nsp3977K977QAaaCaa44B.1.6370.000292
ORF1ab/nsp3977K977KaaAaaG33A.2.50.001497
ORF1ab/nsp3977K977EAaaGaa33AA.40.027273
ORF1ab/nsp3977K977QAaaCaa33AY.230.000209
ORF1ab/nsp3977K977QAaaCaa33AY.610.000314
ORF1ab/nsp3977K977QAaaCaa33AY.75.10.000541
ORF1ab/nsp3977K977QAaaCaa33AY.99.20.000276
ORF1ab/nsp3977K977NaaAaaC33B.1.1.370.000579
ORF1ab/nsp3977K977QAaaCaa33B.1.1.3720.002066
ORF1ab/nsp3977K977KaaAaaG33B.1.1770.00004
ORF1ab/nsp3977K977EAaaGaa33B.1.177.100.002634
ORF1ab/nsp3977K977QAaaCaa33B.1.177.70.000495
ORF1ab/nsp3977K977QAaaCaa33B.1.20.000026
ORF1ab/nsp3977K977KaaAaaG33B.1.5610.001191
ORF1ab/nsp3977K977QAaaCaa33B.1.5960.000261
ORF1ab/nsp3977K977NaaAaaT33B.1.617.20.000011
ORF1ab/nsp3977K977KaaAaaG33P.20.00056
ORF1ab/nsp3977K977CAAATGC22All0
ORF1ab/nsp3977K977KaaAaaG22AY.250.000012
ORF1ab/nsp3977K977QAaaCaa22AY.30.00002
ORF1ab/nsp3977K977QAaaCaa22AY.390.000049
ORF1ab/nsp3977K977KaaAaaG22AY.4.20.000043
ORF1ab/nsp3977K977QAaaCaa22AY.470.000062
ORF1ab/nsp3977K977QAaaCaa22AY.620.000871
ORF1ab/nsp3977K977RaAaaGa22AY.670.000929
ORF1ab/nsp3977K977KaaAaaG22AY.980.000158
ORF1ab/nsp3977K977QAaaCaa22B.1.1.2200.003717
ORF1ab/nsp3977K977QAaaCaa22B.1.1.4090.005666
ORF1ab/nsp3977K977IaAaaTa22B.1.1.5190.000079
ORF1ab/nsp3977K977QAaaCaa22B.1.1.5190.000079
ORF1ab/nsp3977K977NaaAaaT22B.1.1.5190.000079
ORF1ab/nsp3977K977QAaaCaa22B.1.1.540.006042
ORF1ab/nsp3977K977CAAATGC22B.1.1.70.000002
ORF1ab/nsp3977K977NaaAaaC22B.1.1770.000026
ORF1ab/nsp3977K977QAaaCaa22B.1.177.730.001133
ORF1ab/nsp3977K977QAaaCaa22B.1.3110.000549
ORF1ab/nsp3977K977QAaaCaa22B.1.3490.00143
ORF1ab/nsp3977K977RaAaaGa22B.1.3510.000059
ORF1ab/nsp3977K977delAAA---22B.1.360.000292
ORF1ab/nsp3977K977KaaAaaG22B.1.4680.011429
ORF1ab/nsp3977K977KaaAaaG22B.1.5960.000174
ORF1ab/nsp3977K977QAaaCaa22B.1.6230.001073
ORF1ab/nsp3977K977QAaaCaa22B.1.6360.013423
ORF1ab/nsp3977K977NaaAaaC22B.400.000729
ORF1ab/nsp3977K977EAaaGaa11A0.000387
ORF1ab/nsp3977K977KaaAaaG11A0.000387
ORF1ab/nsp3977K977QAaaCaa11A.2.20.001689
ORF1ab/nsp3977K977delAAA---11A.2.20.001689
ORF1ab/nsp3977K977DAaAGaC11All0
ORF1ab/nsp3977K977NaaAaaT11AY.1000.000046
ORF1ab/nsp3977K977QAaaCaa11AY.1000.000046
ORF1ab/nsp3977K977QAaaCaa11AY.1020.000027
ORF1ab/nsp3977K977QAaaCaa11AY.1030.000006
ORF1ab/nsp3977K977KaaAaaG11AY.1140.000231
ORF1ab/nsp3977K977KaaAaaG11AY.1180.000063
ORF1ab/nsp3977K977RaAAaGG11AY.1190.000035
ORF1ab/nsp3977K977KaaAaaG11AY.1190.000035
ORF1ab/nsp3977K977QAaaCaa11AY.1190.000035
ORF1ab/nsp3977K977QAaaCaa11AY.120.20.001285
ORF1ab/nsp3977K977KaaAaaG11AY.130.000161
ORF1ab/nsp3977K977TaAaaCa11AY.180.010101
ORF1ab/nsp3977K977QAaaCaa11AY.20.000356
ORF1ab/nsp3977K977KaaAaaG11AY.230.00007
ORF1ab/nsp3977K977NaaAaaT11AY.230.00007
ORF1ab/nsp3977K977EAaaGaa11AY.230.00007
ORF1ab/nsp3977K977TaAaaCa11AY.250.000006
ORF1ab/nsp3977K977RaAAaGG11AY.250.000006
ORF1ab/nsp3977K977EAaaGaa11AY.280.00189
ORF1ab/nsp3977K977NaaAaaT11AY.30.00001
ORF1ab/nsp3977K977KaaAaaG11AY.300.000396
ORF1ab/nsp3977K977RaAaaGa11AY.330.000067
ORF1ab/nsp3977K977QAaaCaa11AY.340.000097
ORF1ab/nsp3977K977delAAA---11AY.350.000233
ORF1ab/nsp3977K977EAaaGaa11AY.350.000233
ORF1ab/nsp3977K977KaaAaaG11AY.39.10.00004
ORF1ab/nsp3977K977RaAaaGa11AY.40.000002
ORF1ab/nsp3977K977RaAaaGa11AY.410.000294
ORF1ab/nsp3977K977RaAAaGG11AY.420.00004
ORF1ab/nsp3977K977KaaAaaG11AY.420.00004
ORF1ab/nsp3977K977QAaaCaa11AY.420.00004
ORF1ab/nsp3977K977delAAA---11AY.430.000004
ORF1ab/nsp3977K977TaAaaCa11AY.430.000004
ORF1ab/nsp3977K977NaaAaaC11AY.440.000006
ORF1ab/nsp3977K977QAaaCaa11AY.450.000122
ORF1ab/nsp3977K977delAAA---11AY.460.000104
ORF1ab/nsp3977K977NaaAaaC11AY.46.50.000198
ORF1ab/nsp3977K977QAaaCaa11AY.46.60.000072
ORF1ab/nsp3977K977RaAaaGa11AY.50.000021
ORF1ab/nsp3977K977RaAAaGG11AY.5.40.000277
ORF1ab/nsp3977K977KaaAaaG11AY.590.00053
ORF1ab/nsp3977K977KaaAaaG11AY.640.000595
ORF1ab/nsp3977K977delAAA---11AY.710.000475
ORF1ab/nsp3977K977QAaaCaa11AY.710.000475
ORF1ab/nsp3977K977QAaaCaa11AY.740.000116
ORF1ab/nsp3977K977KaaAaaG11AY.740.000116
ORF1ab/nsp3977K977RaAaaGa11AY.750.000056
ORF1ab/nsp3977K977QAaaCaa11AY.750.000056
ORF1ab/nsp3977K977delAAA---11AY.75.10.00018
ORF1ab/nsp3977K977QAaaCaa11AY.840.000437
ORF1ab/nsp3977K977KaaAaaG11AY.99.20.000092
ORF1ab/nsp3977K977delAAA---11B.10.000009
ORF1ab/nsp3977K977TaAaaCa11B.10.000009
ORF1ab/nsp3977K977RaAaaGa11B.10.000009
ORF1ab/nsp3977K977EAaaGaa11B.10.000009
ORF1ab/nsp3977K977QAaaCaa11B.1.1.1210.002427
ORF1ab/nsp3977K977delAAA---11B.1.1.1420.017544
ORF1ab/nsp3977K977QAaaCaa11B.1.1.1980.001468
ORF1ab/nsp3977K977QAaaCaa11B.1.1.2410.00207
ORF1ab/nsp3977K977delAAA---11B.1.1.3150.008475
ORF1ab/nsp3977K977KaaAaaG11B.1.1.3690.000446
ORF1ab/nsp3977K977RaAaaGa11B.1.1.3970.002252
ORF1ab/nsp3977K977RaAaaGa11B.1.1.5190.00004
ORF1ab/nsp3977K977RaAaaGa11B.1.1600.000031
ORF1ab/nsp3977K977QAaaCaa11B.1.1700.00431
ORF1ab/nsp3977K977TaAaaCa11B.1.1770.000013
ORF1ab/nsp3977K977EAaaGaa11B.1.177.570.000281
ORF1ab/nsp3977K977QAaaCaa11B.1.177.860.000183
ORF1ab/nsp3977K977QAaaCaa11B.1.1790.003759
ORF1ab/nsp3977K977EAaaGaa11B.1.20.000009
ORF1ab/nsp3977K977IaAaaTa11B.1.20.000009
ORF1ab/nsp3977K977KaaAaaG11B.1.20.000009
ORF1ab/nsp3977K977TaAaaCa11B.1.2060.000816
ORF1ab/nsp3977K977QAaaCaa11B.1.2140.003663
ORF1ab/nsp3977K977QAaaCaa11B.1.2210.000071
ORF1ab/nsp3977K977RaAaaGa11B.1.221.40.004167
ORF1ab/nsp3977K977IaAaaTa11B.1.2340.000132
ORF1ab/nsp3977K977KaaAaaG11B.1.2390.001221
ORF1ab/nsp3977K977TaAaaCa11B.1.3110.000275
ORF1ab/nsp3977K977delAAA---11B.1.3190.003049
ORF1ab/nsp3977K977QAaaCaa11B.1.3320.003497
ORF1ab/nsp3977K977KaaAaaG11B.1.3510.00003
ORF1ab/nsp3977K977QAaaCaa11B.1.3510.00003
ORF1ab/nsp3977K977KaaAaaG11B.1.360.000146
ORF1ab/nsp3977K977QAaaCaa11B.1.3690.000285
ORF1ab/nsp3977K977QAaaCaa11B.1.3750.00082
ORF1ab/nsp3977K977EAaaGaa11B.1.3750.00082
ORF1ab/nsp3977K977EAaaGaa11B.1.3850.010638
ORF1ab/nsp3977K977KaaAaaG11B.1.3960.000706
ORF1ab/nsp3977K977QAaaCaa11B.1.4150.014286
ORF1ab/nsp3977K977KaaAaaG11B.1.4270.00005
ORF1ab/nsp3977K977KaaAaaG11B.1.4740.001901
ORF1ab/nsp3977K977KaaAaaG11B.1.4970.000315
ORF1ab/nsp3977K977RaAaaGa11B.1.4990.00105
ORF1ab/nsp3977K977QAaaCaa11B.1.5030.002488
ORF1ab/nsp3977K977RaAaaGa11B.1.5240.001406
ORF1ab/nsp3977K977QAaaCaa11B.1.5330.009615
ORF1ab/nsp3977K977TaAaaCa11B.1.5740.002151
ORF1ab/nsp3977K977QAaaCaa11B.1.5820.000491
ORF1ab/nsp3977K977KaaAaaG11B.1.5950.000261
ORF1ab/nsp3977K977NaaAaaC11B.1.5960.000087
ORF1ab/nsp3977K977KaaAaaG11B.1.6020.006536
ORF1ab/nsp3977K977NaaAaaT11B.1.6090.000479
ORF1ab/nsp3977K977RaAaaGa11B.1.617.20.000004
ORF1ab/nsp3977K977EAaaGaa11B.1.617.20.000004
ORF1ab/nsp3977K977delAAA---11B.1.617.20.000004
ORF1ab/nsp3977K977QAaaCaa11B.1.6200.000946
ORF1ab/nsp3977K977KaaAaaG11B.1.6210.000089
ORF1ab/nsp3977K977KaaAaaG11B.1.621.10.000506
ORF1ab/nsp3977K977NaaAaaT11B.1.6370.000073
ORF1ab/nsp3977K977QAaaCaa11B.1.930.000934
ORF1ab/nsp3977K977delAAA---11B.150.017544
ORF1ab/nsp3977K977DAaAGaC11C.350.000774
ORF1ab/nsp3977K977QAaaCaa11C.350.000774
ORF1ab/nsp3977K977delAAA---11C.370.000116
ORF1ab/nsp3977K977KaaAaaG11D.20.000075
ORF1ab/nsp3977K977RaAaaGa11P.20.000187

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.