CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 923

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3923L923LL1741LsynttAttG331832790.9882465486-5488
ORF1ab/nsp3923L923LL1741LsynTtaCta3318390.01175415486-5488
ORF1ab/nsp3923L923VL1741VnonsynTtaGta11711715486-5488
ORF1ab/nsp3923L923delL1741deldelTTA---262615486-5488
ORF1ab/nsp3923L923SL1741SnonsyntTatCa121215486-5488
ORF1ab/nsp3923L923IL1741InonsynTtaAta8815486-5488
ORF1ab/nsp3923L923FL1741FnonsynttAttT8815486-5488
ORF1ab/nsp3923L923XL1741XnonsyntTatGa640.6666675486-5488
ORF1ab/nsp3923L923XL1741XnonsyntTatAa620.3333335486-5488
ORF1ab/nsp3923L923CL1741CnonsyntTAtGT2215486-5488
ORF1ab/nsp3923L923PL1741PnonsynTTACCT1115486-5488
ORF1ab/nsp3923L923del1L1741del1delTTa-Ca1115486-5488
ORF1ab/nsp3923L923GL1741GnonsynTTaGGa1115486-5488

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3923L923LttAttG32793318All0.000627
ORF1ab/nsp3923L923LTtaCta393318All0.000007
ORF1ab/nsp3923L923LttAttG19261926A.2.50.961078
ORF1ab/nsp3923L923LttAttG619619A.2.5.20.97327
ORF1ab/nsp3923L923LttAttG208208A.2.5.11
ORF1ab/nsp3923L923VTtaGta117117All0.000022
ORF1ab/nsp3923L923VTtaGta113113AY.1030.000702
ORF1ab/nsp3923L923LttAttG8787A.2.5.30.896907
ORF1ab/nsp3923L923LttAttG6667AY.250.000397
ORF1ab/nsp3923L923LTtaCta167AY.250.000006
ORF1ab/nsp3923L923LttAttG4040B.1.4270.00202
ORF1ab/nsp3923L923LttAttG3535B.1.2430.002435
ORF1ab/nsp3923L923LttAttG3232AY.440.000195
ORF1ab/nsp3923L923LttAttG2929AY.470.000902
ORF1ab/nsp3923L923LttAttG2228B.1.1.70.00002
ORF1ab/nsp3923L923LTtaCta628B.1.1.70.000005
ORF1ab/nsp3923L923delTTA---2626All0.000005
ORF1ab/nsp3923L923LttAttG2626AY.40.00004
ORF1ab/nsp3923L923LttAttG2424B.1.3510.000713
ORF1ab/nsp3923L923LttAttG1821B.1.20.000158
ORF1ab/nsp3923L923LTtaCta321B.1.20.000026
ORF1ab/nsp3923L923LttAttG1414AY.200.000544
ORF1ab/nsp3923L923LttAttG1314B.1.617.20.000049
ORF1ab/nsp3923L923LTtaCta114B.1.617.20.000004
ORF1ab/nsp3923L923LttAttG1313AY.1180.000814
ORF1ab/nsp3923L923LttAttG1313C.370.001509
ORF1ab/nsp3923L923StTatCa1212All0.000002
ORF1ab/nsp3923L923LTtaCta611B.1.10.000109
ORF1ab/nsp3923L923LttAttG511B.1.10.000091
ORF1ab/nsp3923L923FttAttT88All0.000002
ORF1ab/nsp3923L923ITtaAta88All0.000002
ORF1ab/nsp3923L923LttAttG88AY.50.000165
ORF1ab/nsp3923L923delTTA---88B.1.1.70.000007
ORF1ab/nsp3923L923XtTatGa46All0.000001
ORF1ab/nsp3923L923XtTatAa26All0
ORF1ab/nsp3923L923LttAttG56B.1.4290.000118
ORF1ab/nsp3923L923LTtaCta16B.1.4290.000024
ORF1ab/nsp3923L923LttAttG55A.20.003309
ORF1ab/nsp3923L923LttAttG55AY.1030.000031
ORF1ab/nsp3923L923LttAttG45B.10.000037
ORF1ab/nsp3923L923LTtaCta15B.10.000009
ORF1ab/nsp3923L923LttAttG55B.1.5960.000436
ORF1ab/nsp3923L923FttAttT440.222222
ORF1ab/nsp3923L923LttAttG44P.10.000063
ORF1ab/nsp3923L923LttAttG33AY.30.00003
ORF1ab/nsp3923L923LTtaCta33AY.330.0002
ORF1ab/nsp3923L923LttAttG33AY.39.10.000119
ORF1ab/nsp3923L923delTTA---33AY.40.000005
ORF1ab/nsp3923L923LTtaCta33AY.99.20.000276
ORF1ab/nsp3923L923LttAttG33B.1.1770.00004
ORF1ab/nsp3923L923XtTatGa220.111111
ORF1ab/nsp3923L923CtTAtGT220.111111
ORF1ab/nsp3923L923LttAttG22A0.000774
ORF1ab/nsp3923L923CtTAtGT22All0
ORF1ab/nsp3923L923LttAttG12AY.1020.000027
ORF1ab/nsp3923L923LTtaCta12AY.1020.000027
ORF1ab/nsp3923L923LTtaCta22AY.4.20.000043
ORF1ab/nsp3923L923LttAttG22AY.420.00008
ORF1ab/nsp3923L923LTtaCta12AY.430.000004
ORF1ab/nsp3923L923LttAttG12AY.430.000004
ORF1ab/nsp3923L923LttAttG22AY.610.00021
ORF1ab/nsp3923L923LTtaCta12B0.000128
ORF1ab/nsp3923L923LttAttG12B0.000128
ORF1ab/nsp3923L923LTtaCta22B.1.1.1340.022727
ORF1ab/nsp3923L923LttAttG22B.1.1.2650.006309
ORF1ab/nsp3923L923LttAttG22B.1.1.4160.00181
ORF1ab/nsp3923L923LttAttG22B.1.1570.00597
ORF1ab/nsp3923L923LttAttG22B.1.2390.002442
ORF1ab/nsp3923L923LttAttG22B.1.2580.000133
ORF1ab/nsp3923L923delTTA---22B.1.360.000292
ORF1ab/nsp3923L923delTTA---22B.1.617.20.000008
ORF1ab/nsp3923L923ITtaAta22D.20.00015
ORF1ab/nsp3923L923LttAttG11A.10.000282
ORF1ab/nsp3923L923delTTA---11A.2.20.001689
ORF1ab/nsp3923L923XtTatGa11A.2.40.003367
ORF1ab/nsp3923L923LttAttG11A.2.40.003367
ORF1ab/nsp3923L923ITtaAta11A.290.005319
ORF1ab/nsp3923L923PTTACCT11All0
ORF1ab/nsp3923L923GTTaGGa11All0
ORF1ab/nsp3923L923del1TTa-Ca11All0
ORF1ab/nsp3923L923FttAttT11AY.1030.000006
ORF1ab/nsp3923L923StTatCa11AY.1030.000006
ORF1ab/nsp3923L923LttAttG11AY.1070.000466
ORF1ab/nsp3923L923LttAttG11AY.1080.001103
ORF1ab/nsp3923L923delTTA---11AY.1080.001103
ORF1ab/nsp3923L923del1TTa-Ca11AY.1190.000035
ORF1ab/nsp3923L923LTtaCta11AY.230.00007
ORF1ab/nsp3923L923FttAttT11AY.250.000006
ORF1ab/nsp3923L923PTTACCT11AY.260.000028
ORF1ab/nsp3923L923StTatCa11AY.260.000028
ORF1ab/nsp3923L923delTTA---11AY.260.000028
ORF1ab/nsp3923L923LttAttG11AY.260.000028
ORF1ab/nsp3923L923StTatCa11AY.30.00001
ORF1ab/nsp3923L923LttAttG11AY.390.000025
ORF1ab/nsp3923L923ITtaAta11AY.440.000006
ORF1ab/nsp3923L923LttAttG11AY.450.000122
ORF1ab/nsp3923L923LttAttG11AY.460.000104
ORF1ab/nsp3923L923VTtaGta11AY.50.000021
ORF1ab/nsp3923L923delTTA---11AY.660.00107
ORF1ab/nsp3923L923StTatCa11AY.680.000274
ORF1ab/nsp3923L923LttAttG11AY.690.000187
ORF1ab/nsp3923L923StTatCa11AY.750.000056
ORF1ab/nsp3923L923ITtaAta11AY.820.001357
ORF1ab/nsp3923L923delTTA---11AY.99.10.001553
ORF1ab/nsp3923L923StTatCa11B.10.000009
ORF1ab/nsp3923L923delTTA---11B.10.000009
ORF1ab/nsp3923L923VTtaGta11B.10.000009
ORF1ab/nsp3923L923XtTatAa11B.10.000009
ORF1ab/nsp3923L923FttAttT11B.10.000009
ORF1ab/nsp3923L923StTatCa11B.1.10.000018
ORF1ab/nsp3923L923StTatCa11B.1.1.10.000327
ORF1ab/nsp3923L923delTTA---11B.1.1.1420.017544
ORF1ab/nsp3923L923LttAttG11B.1.1.2160.00089
ORF1ab/nsp3923L923LttAttG11B.1.1.2200.001859
ORF1ab/nsp3923L923FttAttT11B.1.1.2440.015385
ORF1ab/nsp3923L923LTtaCta11B.1.1.250.000569
ORF1ab/nsp3923L923VTtaGta11B.1.1.3980.003226
ORF1ab/nsp3923L923LttAttG11B.1.1.4070.041667
ORF1ab/nsp3923L923VTtaGta11B.1.1.4090.002833
ORF1ab/nsp3923L923LttAttG11B.1.1.630.000386
ORF1ab/nsp3923L923ITtaAta11B.1.1.70.000001
ORF1ab/nsp3923L923LttAttG11B.1.1600.000031
ORF1ab/nsp3923L923XtTatAa11B.1.1600.000031
ORF1ab/nsp3923L923delTTA---11B.1.1600.000031
ORF1ab/nsp3923L923ITtaAta11B.1.177.230.003236
ORF1ab/nsp3923L923LttAttG11B.1.177.40.000211
ORF1ab/nsp3923L923StTatCa11B.1.177.40.000211
ORF1ab/nsp3923L923delTTA---11B.1.20.000009
ORF1ab/nsp3923L923StTatCa11B.1.20.000009
ORF1ab/nsp3923L923ITtaAta11B.1.20.000009
ORF1ab/nsp3923L923XtTatGa11B.1.2430.00007
ORF1ab/nsp3923L923StTatCa11B.1.2580.000067
ORF1ab/nsp3923L923LttAttG11B.1.258.170.000104
ORF1ab/nsp3923L923delTTA---11B.1.3190.003049
ORF1ab/nsp3923L923LttAttG11B.1.3380.008621
ORF1ab/nsp3923L923LttAttG11B.1.360.000146
ORF1ab/nsp3923L923GTTaGGa11B.1.4620.007246
ORF1ab/nsp3923L923LttAttG11B.1.5610.000397
ORF1ab/nsp3923L923LTtaCta11B.1.5760.000907
ORF1ab/nsp3923L923LttAttG11B.1.5800.004065
ORF1ab/nsp3923L923LTtaCta11B.1.5810.009434
ORF1ab/nsp3923L923LttAttG11B.1.5950.000261
ORF1ab/nsp3923L923LttAttG11B.1.6210.000089
ORF1ab/nsp3923L923LttAttG11B.1.6280.000352
ORF1ab/nsp3923L923delTTA---11B.150.017544
ORF1ab/nsp3923L923LttAttG11B.520.010101
ORF1ab/nsp3923L923StTatCa11D.20.000075
ORF1ab/nsp3923L923LTtaCta11P.1.100.000269
ORF1ab/nsp3923L923LTtaCta11P.1.150.000232
ORF1ab/nsp3923L923LTtaCta11P.1.50.076923
ORF1ab/nsp3923L923LttAttG11P.1.70.000319

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.