CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 81

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp381E81DE899DnonsyngaGgaT4324290.9930562960-2962
ORF1ab/nsp381E81DE899DnonsyngaGgaC43230.006944442960-2962
ORF1ab/nsp381E81EE899EsyngaGgaA15015012960-2962
ORF1ab/nsp381E81GE899GnonsyngAggGg98940.9591842960-2962
ORF1ab/nsp381E81GE899GnonsyngAGgGT9820.02040822960-2962
ORF1ab/nsp381E81GE899GnonsyngAGgGC9810.01020412960-2962
ORF1ab/nsp381E81GE899GnonsyngAGgGA9810.01020412960-2962
ORF1ab/nsp381E81delE899deldelGAG---444412960-2962
ORF1ab/nsp381E81AE899AnonsyngAggCg161612960-2962
ORF1ab/nsp381E81VE899VnonsyngAggTg12110.9166672960-2962
ORF1ab/nsp381E81VE899VnonsyngAGgTT1210.08333332960-2962
ORF1ab/nsp381E81KE899KnonsynGagAag111112960-2962
ORF1ab/nsp381E81XE899XnonsynGagTag1190.8181822960-2962
ORF1ab/nsp381E81del1E899del1delgAgg-g1150.4545452960-2962
ORF1ab/nsp381E81del1E899del1delgAGgG-1130.2727272960-2962
ORF1ab/nsp381E81XE899XnonsynGAGTGA1120.1818182960-2962
ORF1ab/nsp381E81del1E899del1delgaGga-1120.1818182960-2962
ORF1ab/nsp381E81del1E899del1delGAg-Tg1110.09090912960-2962
ORF1ab/nsp381E81RE899RnonsynGAGAGA420.52960-2962
ORF1ab/nsp381E81RE899RnonsynGAgCGg410.252960-2962
ORF1ab/nsp381E81RE899RnonsynGAgAGg410.252960-2962
ORF1ab/nsp381E81CE899CnonsynGAGTGT2212960-2962
ORF1ab/nsp381E81del2E899del2delgAGg--2212960-2962
ORF1ab/nsp381E81QE899QnonsynGagCag2212960-2962
ORF1ab/nsp381E81SE899SnonsynGAGAGT2212960-2962
ORF1ab/nsp381E81YE899YnonsynGaGTaC1112960-2962
ORF1ab/nsp381E81ME899MnonsynGAgATg1112960-2962

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp381E81DgaGgaT429432All0.000082
ORF1ab/nsp381E81DgaGgaC3432All0.000001
ORF1ab/nsp381E81EgaGgaA150150All0.000029
ORF1ab/nsp381E81DgaGgaT109110B.1.1.70.000098
ORF1ab/nsp381E81DgaGgaC1110B.1.1.70.000001
ORF1ab/nsp381E81GgAggGg9498All0.000018
ORF1ab/nsp381E81GgAGgGT298All0
ORF1ab/nsp381E81GgAGgGA198All0
ORF1ab/nsp381E81GgAGgGC198All0
ORF1ab/nsp381E81GgAggGg4848B.1.1.70.000043
ORF1ab/nsp381E81delGAG---4444All0.000008
ORF1ab/nsp381E81DgaGgaT4042B.1.617.20.000151
ORF1ab/nsp381E81DgaGgaC242B.1.617.20.000008
ORF1ab/nsp381E81DgaGgaT3030AY.40.000047
ORF1ab/nsp381E81EgaGgaA2626B.1.2890.069149
ORF1ab/nsp381E81EgaGgaA2424B.1.3510.000713
ORF1ab/nsp381E81DgaGgaT2222B.1.177.610.956522
ORF1ab/nsp381E81DgaGgaT2121AY.150.046667
ORF1ab/nsp381E81DgaGgaT2121AY.430.000093
ORF1ab/nsp381E81AgAggCg1616All0.000003
ORF1ab/nsp381E81DgaGgaT1616AY.750.000896
ORF1ab/nsp381E81DgaGgaT1515AY.1050.009646
ORF1ab/nsp381E81EgaGgaA1414AY.30.000139
ORF1ab/nsp381E81EgaGgaA1313B.1.1.70.000012
ORF1ab/nsp381E81DgaGgaT1313P.10.000205
ORF1ab/nsp381E81VgAggTg1112All0.000002
ORF1ab/nsp381E81VgAGgTT112All0
ORF1ab/nsp381E81GgAggGg1212AY.40.000019
ORF1ab/nsp381E81DgaGgaT1212AY.9.10.001005
ORF1ab/nsp381E81KGagAag1111All0.000002
ORF1ab/nsp381E81XGagTag911All0.000002
ORF1ab/nsp381E81del1gAgg-g511All0.000001
ORF1ab/nsp381E81del1gAGgG-311All0.000001
ORF1ab/nsp381E81XGAGTGA211All0
ORF1ab/nsp381E81del1gaGga-211All0
ORF1ab/nsp381E81del1GAg-Tg111All0
ORF1ab/nsp381E81GgAggGg88AY.1030.00005
ORF1ab/nsp381E81EgaGgaA88B.10.000073
ORF1ab/nsp381E81delGAG---88B.1.1.70.000007
ORF1ab/nsp381E81DgaGgaT88B.1.177.150.005047
ORF1ab/nsp381E81EgaGgaA88B.1.20.00007
ORF1ab/nsp381E81DgaGgaT77AY.440.000043
ORF1ab/nsp381E81KGagAag77B.1.1.70.000006
ORF1ab/nsp381E81DgaGgaT66B.1.1.3020.012448
ORF1ab/nsp381E81DgaGgaT66B.1.3670.004754
ORF1ab/nsp381E81DgaGgaT66B.1.621.10.003035
ORF1ab/nsp381E81DgaGgaT55B.1.1770.000066
ORF1ab/nsp381E81DgaGgaT55B.1.258.170.00052
ORF1ab/nsp381E81EgaGgaA55P.10.000079
ORF1ab/nsp381E81EgaGgaA440.222222
ORF1ab/nsp381E81RGAGAGA24All0
ORF1ab/nsp381E81RGAgAGg14All0
ORF1ab/nsp381E81RGAgCGg14All0
ORF1ab/nsp381E81DgaGgaT44AY.1020.000106
ORF1ab/nsp381E81DgaGgaT44AY.1030.000025
ORF1ab/nsp381E81DgaGgaT44AY.250.000024
ORF1ab/nsp381E81EgaGgaA44AY.39.20.006163
ORF1ab/nsp381E81EgaGgaA44AY.430.000018
ORF1ab/nsp381E81AgAggCg44AY.50.000083
ORF1ab/nsp381E81DgaGgaT44B.1.10.000073
ORF1ab/nsp381E81EgaGgaA44B.1.160.290.016878
ORF1ab/nsp381E81DgaGgaT44B.1.20.000035
ORF1ab/nsp381E81DgaGgaT44B.1.3690.001141
ORF1ab/nsp381E81AgAggCg44B.1.617.20.000015
ORF1ab/nsp381E81DgaGgaT33AY.1170.000254
ORF1ab/nsp381E81DgaGgaT33AY.9.20.00011
ORF1ab/nsp381E81delGAG---33B.10.000027
ORF1ab/nsp381E81delGAG---33B.1.1.330.001263
ORF1ab/nsp381E81EgaGgaA33B.1.1.340.039474
ORF1ab/nsp381E81DgaGgaT33B.1.5260.000071
ORF1ab/nsp381E81delGAG---33B.1.617.20.000011
ORF1ab/nsp381E81EgaGgaA33B.1.617.20.000011
ORF1ab/nsp381E81GgAggGg33B.1.6280.001057
ORF1ab/nsp381E81RGAGAGA220.111111
ORF1ab/nsp381E81SGAGAGT220.111111
ORF1ab/nsp381E81delGAG---220.111111
ORF1ab/nsp381E81XGAGTGA220.111111
ORF1ab/nsp381E81CGAGTGT220.111111
ORF1ab/nsp381E81DgaGgaT22AD.20.000438
ORF1ab/nsp381E81CGAGTGT22All0
ORF1ab/nsp381E81SGAGAGT22All0
ORF1ab/nsp381E81QGagCag22All0
ORF1ab/nsp381E81del2gAGg--22All0
ORF1ab/nsp381E81DgaGgaT22AY.100.00106
ORF1ab/nsp381E81EgaGgaA22AY.1030.000012
ORF1ab/nsp381E81DgaGgaT22AY.1190.000071
ORF1ab/nsp381E81EgaGgaA22AY.250.000012
ORF1ab/nsp381E81DgaGgaT22AY.260.000057
ORF1ab/nsp381E81DgaGgaT22AY.290.000032
ORF1ab/nsp381E81VgAggTg22AY.30.00002
ORF1ab/nsp381E81EgaGgaA22AY.3.10.000171
ORF1ab/nsp381E81EgaGgaA22AY.40.000003
ORF1ab/nsp381E81delGAG---22AY.430.000009
ORF1ab/nsp381E81VgAggTg22AY.430.000009
ORF1ab/nsp381E81EgaGgaA22AY.450.000243
ORF1ab/nsp381E81DgaGgaT22AY.50.000041
ORF1ab/nsp381E81EgaGgaA22AY.540.000191
ORF1ab/nsp381E81DgaGgaT22AY.980.000158
ORF1ab/nsp381E81XGagTag22B.1.10.000036
ORF1ab/nsp381E81delGAG---22B.1.10.000036
ORF1ab/nsp381E81DgaGgaT22B.1.1.2690.002706
ORF1ab/nsp381E81delGAG---22B.1.1.3480.001592
ORF1ab/nsp381E81GgAggGg12B.1.1.470.005348
ORF1ab/nsp381E81GgAGgGT12B.1.1.470.005348
ORF1ab/nsp381E81delGAG---22B.1.177.540.001213
ORF1ab/nsp381E81DgaGgaT22B.1.177.820.000955
ORF1ab/nsp381E81del1gAgg-g22B.1.20.000018
ORF1ab/nsp381E81GgAGgGA12B.1.20.000009
ORF1ab/nsp381E81GgAGgGC12B.1.20.000009
ORF1ab/nsp381E81DgaGgaT22B.1.4250.005988
ORF1ab/nsp381E81DgaGgaT22B.1.4290.000047
ORF1ab/nsp381E81EgaGgaA22B.1.5820.000981
ORF1ab/nsp381E81VgAggTg12B.1.617.20.000004
ORF1ab/nsp381E81VgAGgTT12B.1.617.20.000004
ORF1ab/nsp381E81DgaGgaT22B.1.6210.000177
ORF1ab/nsp381E81XGagTag22B.60.00182
ORF1ab/nsp381E81DgaGgaT22D.20.00015
ORF1ab/nsp381E81delGAG---22N.60.014184
ORF1ab/nsp381E81delGAG---22P.10.000032
ORF1ab/nsp381E81EgaGgaA22Q.10.000253
ORF1ab/nsp381E81MGAgATg11All0
ORF1ab/nsp381E81YGaGTaC11All0
ORF1ab/nsp381E81del2gAGg--11AY.1000.000046
ORF1ab/nsp381E81XGagTag11AY.1020.000027
ORF1ab/nsp381E81EgaGgaA11AY.1020.000027
ORF1ab/nsp381E81VgAggTg11AY.1030.000006
ORF1ab/nsp381E81del1gAGgG-11AY.1030.000006
ORF1ab/nsp381E81del1gAgg-g11AY.1130.000142
ORF1ab/nsp381E81DgaGgaT11AY.1140.000231
ORF1ab/nsp381E81GgAGgGT11AY.1200.000037
ORF1ab/nsp381E81DgaGgaT11AY.130.000161
ORF1ab/nsp381E81DgaGgaT11AY.190.00114
ORF1ab/nsp381E81EgaGgaA11AY.200.000039
ORF1ab/nsp381E81XGagTag11AY.230.00007
ORF1ab/nsp381E81KGagAag11AY.250.000006
ORF1ab/nsp381E81delGAG---11AY.250.000006
ORF1ab/nsp381E81delGAG---11AY.260.000028
ORF1ab/nsp381E81DgaGgaT11AY.270.000065
ORF1ab/nsp381E81AgAggCg11AY.290.000016
ORF1ab/nsp381E81GgAggGg11AY.290.000016
ORF1ab/nsp381E81del1gaGga-11AY.30.00001
ORF1ab/nsp381E81DgaGgaT11AY.30.00001
ORF1ab/nsp381E81DgaGgaT11AY.34.10.00051
ORF1ab/nsp381E81DgaGgaT11AY.380.000499
ORF1ab/nsp381E81EgaGgaA11AY.390.000025
ORF1ab/nsp381E81GgAggGg11AY.390.000025
ORF1ab/nsp381E81QGagCag11AY.40.000002
ORF1ab/nsp381E81KGagAag11AY.40.000002
ORF1ab/nsp381E81AgAggCg11AY.40.000002
ORF1ab/nsp381E81GgAggGg11AY.4.50.000107
ORF1ab/nsp381E81DgaGgaT11AY.410.000294
ORF1ab/nsp381E81delGAG---11AY.420.00004
ORF1ab/nsp381E81YGaGTaC11AY.440.000006
ORF1ab/nsp381E81GgAggGg11AY.440.000006
ORF1ab/nsp381E81EgaGgaA11AY.440.000006
ORF1ab/nsp381E81AgAggCg11AY.440.000006
ORF1ab/nsp381E81del1gAgg-g11AY.440.000006
ORF1ab/nsp381E81delGAG---11AY.460.000104
ORF1ab/nsp381E81DgaGgaT11AY.46.20.000635
ORF1ab/nsp381E81DgaGgaT11AY.540.000095
ORF1ab/nsp381E81GgAggGg11AY.60.000041
ORF1ab/nsp381E81GgAggGg11AY.670.000464
ORF1ab/nsp381E81EgaGgaA11AY.690.000187
ORF1ab/nsp381E81GgAggGg11AY.750.000056
ORF1ab/nsp381E81del1gAGgG-11AY.790.001211
ORF1ab/nsp381E81EgaGgaA11AY.9.10.000084
ORF1ab/nsp381E81AgAggCg11AY.98.10.000048
ORF1ab/nsp381E81delGAG---11AY.990.001049
ORF1ab/nsp381E81delGAG---11AZ.20.000821
ORF1ab/nsp381E81del2gAGg--11B0.000128
ORF1ab/nsp381E81del1gaGga-11B.10.000009
ORF1ab/nsp381E81GgAggGg11B.10.000009
ORF1ab/nsp381E81RGAgCGg11B.10.000009
ORF1ab/nsp381E81DgaGgaT11B.10.000009
ORF1ab/nsp381E81EgaGgaA11B.1.10.000018
ORF1ab/nsp381E81DgaGgaT11B.1.1.2160.00089
ORF1ab/nsp381E81GgAggGg11B.1.1.2220.000204
ORF1ab/nsp381E81GgAggGg11B.1.1.250.000569
ORF1ab/nsp381E81GgAggGg11B.1.1.3180.000302
ORF1ab/nsp381E81EgaGgaA11B.1.1.3720.000689
ORF1ab/nsp381E81DgaGgaT11B.1.1.3760.005952
ORF1ab/nsp381E81VgAggTg11B.1.1.390.00051
ORF1ab/nsp381E81DgaGgaT11B.1.1.4640.001473
ORF1ab/nsp381E81DgaGgaT11B.1.1.470.005348
ORF1ab/nsp381E81DgaGgaT11B.1.1.500.000679
ORF1ab/nsp381E81AgAggCg11B.1.1.70.000001
ORF1ab/nsp381E81del1gAgg-g11B.1.1.70.000001
ORF1ab/nsp381E81VgAggTg11B.1.1.70.000001
ORF1ab/nsp381E81QGagCag11B.1.1.70.000001
ORF1ab/nsp381E81EgaGgaA11B.1.1390.000733
ORF1ab/nsp381E81AgAggCg11B.1.1770.000013
ORF1ab/nsp381E81DgaGgaT11B.1.177.210.000076
ORF1ab/nsp381E81AgAggCg11B.1.177.520.001757
ORF1ab/nsp381E81VgAggTg11B.1.177.650.000665
ORF1ab/nsp381E81delGAG---11B.1.20.000009
ORF1ab/nsp381E81XGagTag11B.1.20.000009
ORF1ab/nsp381E81RGAgAGg11B.1.20.000009
ORF1ab/nsp381E81MGAgATg11B.1.20.000009
ORF1ab/nsp381E81DgaGgaT11B.1.2340.000132
ORF1ab/nsp381E81DgaGgaT11B.1.2350.002519
ORF1ab/nsp381E81DgaGgaT11B.1.2390.001221
ORF1ab/nsp381E81GgAggGg11B.1.2400.000216
ORF1ab/nsp381E81delGAG---11B.1.3490.000715
ORF1ab/nsp381E81XGagTag11B.1.3510.00003
ORF1ab/nsp381E81GgAggGg11B.1.3510.00003
ORF1ab/nsp381E81VgAggTg11B.1.360.000146
ORF1ab/nsp381E81AgAggCg11B.1.360.000146
ORF1ab/nsp381E81del1GAg-Tg11B.1.36.180.00042
ORF1ab/nsp381E81DgaGgaT11B.1.36.80.001
ORF1ab/nsp381E81DgaGgaT11B.1.3960.000706
ORF1ab/nsp381E81KGagAag11B.1.3980.002976
ORF1ab/nsp381E81delGAG---11B.1.416.10.001563
ORF1ab/nsp381E81XGagTag11B.1.4290.000024
ORF1ab/nsp381E81delGAG---11B.1.4290.000024
ORF1ab/nsp381E81EgaGgaA11B.1.438.10.000107
ORF1ab/nsp381E81GgAggGg11B.1.466.20.000391
ORF1ab/nsp381E81GgAggGg11B.1.5170.000427
ORF1ab/nsp381E81GgAggGg11B.1.5240.001406
ORF1ab/nsp381E81EgaGgaA11B.1.5260.000024
ORF1ab/nsp381E81GgAggGg11B.1.5260.000024
ORF1ab/nsp381E81EgaGgaA11B.1.5320.006211
ORF1ab/nsp381E81DgaGgaT11B.1.5610.000397
ORF1ab/nsp381E81delGAG---11B.1.5610.000397
ORF1ab/nsp381E81delGAG---11B.1.5770.000687
ORF1ab/nsp381E81DgaGgaT11B.1.617.10.000129
ORF1ab/nsp381E81del1gAGgG-11B.1.617.20.000004
ORF1ab/nsp381E81GgAggGg11B.1.617.20.000004
ORF1ab/nsp381E81KGagAag11B.1.617.20.000004
ORF1ab/nsp381E81EgaGgaA11B.1.619.10.000641
ORF1ab/nsp381E81GgAggGg11B.1.6300.005236
ORF1ab/nsp381E81VgAggTg11B.1.6370.000073
ORF1ab/nsp381E81DgaGgaT11B.1.9.50.005682
ORF1ab/nsp381E81delGAG---11C.170.055556
ORF1ab/nsp381E81GgAggGg11C.370.000116
ORF1ab/nsp381E81EgaGgaA11N.50.001767
ORF1ab/nsp381E81GgAggGg11P.1.150.000232
ORF1ab/nsp381E81DgaGgaT11P.1.170.000162
ORF1ab/nsp381E81DgaGgaT11P.30.001595
ORF1ab/nsp381E81DgaGgaT11Q.10.000126
ORF1ab/nsp381E81GgAggGg11Q.80.000165

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.