CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 764

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3764Q764HQ1582HnonsyncaAcaC383738150.9942665009-5011
ORF1ab/nsp3764Q764HQ1582HnonsyncaAcaT3837220.005733655009-5011
ORF1ab/nsp3764Q764RQ1582RnonsyncAacGa2742730.996355009-5011
ORF1ab/nsp3764Q764RQ1582RnonsyncAAcGG27410.003649645009-5011
ORF1ab/nsp3764Q764LQ1582LnonsyncAacTa16216215009-5011
ORF1ab/nsp3764Q764QQ1582QsyncaAcaG16016015009-5011
ORF1ab/nsp3764Q764KQ1582KnonsynCaaAaa10410415009-5011
ORF1ab/nsp3764Q764delQ1582deldelCAA---808015009-5011
ORF1ab/nsp3764Q764XQ1582XnonsynCaaTaa464615009-5011
ORF1ab/nsp3764Q764YQ1582YnonsynCaATaC1090.95009-5011
ORF1ab/nsp3764Q764YQ1582YnonsynCaATaT1010.15009-5011
ORF1ab/nsp3764Q764PQ1582PnonsyncAacCa4415009-5011
ORF1ab/nsp3764Q764EQ1582EnonsynCaaGaa4415009-5011
ORF1ab/nsp3764Q764del1Q1582del1delCAATG-410.255009-5011
ORF1ab/nsp3764Q764del1Q1582del1delcaAca-410.255009-5011
ORF1ab/nsp3764Q764del1Q1582del1delCaa-aa410.255009-5011
ORF1ab/nsp3764Q764del1Q1582del1delcAac-a410.255009-5011
ORF1ab/nsp3764Q764del2Q1582del2delCAAT--210.55009-5011
ORF1ab/nsp3764Q764del2Q1582del2delcAAc--210.55009-5011
ORF1ab/nsp3764Q764GQ1582GnonsynCAAGGG1115009-5011

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3764Q764HcaAcaC38153837All0.00073
ORF1ab/nsp3764Q764HcaAcaT223837All0.000004
ORF1ab/nsp3764Q764HcaAcaC33133315B.1.3110.909665
ORF1ab/nsp3764Q764HcaAcaT23315B.1.3110.000549
ORF1ab/nsp3764Q764RcAacGa273274All0.000052
ORF1ab/nsp3764Q764RcAAcGG1274All0
ORF1ab/nsp3764Q764HcaAcaC209210B.10.001914
ORF1ab/nsp3764Q764HcaAcaT1210B.10.000009
ORF1ab/nsp3764Q764LcAacTa162162All0.000031
ORF1ab/nsp3764Q764QcaAcaG160160All0.000031
ORF1ab/nsp3764Q764RcAacGa125125AY.40.000195
ORF1ab/nsp3764Q764KCaaAaa104104All0.00002
ORF1ab/nsp3764Q764HcaAcaC9494B.1.1190.989474
ORF1ab/nsp3764Q764delCAA---8080All0.000015
ORF1ab/nsp3764Q764LcAacTa6868AY.440.000414
ORF1ab/nsp3764Q764QcaAcaG5959B.1.1.70.000053
ORF1ab/nsp3764Q764HcaAcaC5757B.1.4440.904762
ORF1ab/nsp3764Q764KCaaAaa5151AY.250.000307
ORF1ab/nsp3764Q764XCaaTaa4646All0.000009
ORF1ab/nsp3764Q764RcAacGa3434B.1.1.70.00003
ORF1ab/nsp3764Q764RcAacGa2929AY.440.000177
ORF1ab/nsp3764Q764LcAacTa2424AY.1030.000149
ORF1ab/nsp3764Q764delCAA---2424B.1.1.70.000021
ORF1ab/nsp3764Q764QcaAcaG2121B.1.617.20.000079
ORF1ab/nsp3764Q764HcaAcaC1220AY.40.000019
ORF1ab/nsp3764Q764HcaAcaT820AY.40.000012
ORF1ab/nsp3764Q764KCaaAaa1919AY.10.007519
ORF1ab/nsp3764Q764QcaAcaG1818B.1.1.2140.000998
ORF1ab/nsp3764Q764HcaAcaC1516B.1.20.000132
ORF1ab/nsp3764Q764HcaAcaT116B.1.20.000009
ORF1ab/nsp3764Q764HcaAcaC1215B.1.1.70.000011
ORF1ab/nsp3764Q764HcaAcaT315B.1.1.70.000003
ORF1ab/nsp3764Q764LcAacTa1414B.1.10.000254
ORF1ab/nsp3764Q764RcAacGa1313B.1.2320.006985
ORF1ab/nsp3764Q764delCAA---1212B.10.00011
ORF1ab/nsp3764Q764QcaAcaG1111AY.850.004699
ORF1ab/nsp3764Q764XCaaTaa1111B.1.1.70.00001
ORF1ab/nsp3764Q764RcAacGa1111B.1.617.20.000041
ORF1ab/nsp3764Q764YCaATaC910All0.000002
ORF1ab/nsp3764Q764YCaATaT110All0
ORF1ab/nsp3764Q764QcaAcaG1010AY.40.000016
ORF1ab/nsp3764Q764XCaaTaa1010B.10.000092
ORF1ab/nsp3764Q764YCaATaC910B.1.3110.002471
ORF1ab/nsp3764Q764YCaATaT110B.1.3110.000275
ORF1ab/nsp3764Q764KCaaAaa99AY.40.000014
ORF1ab/nsp3764Q764LcAacTa99AY.570.005906
ORF1ab/nsp3764Q764HcaAcaC99B.1.5170.003843
ORF1ab/nsp3764Q764HcaAcaC88B.1.177.810.001515
ORF1ab/nsp3764Q764HcaAcaC88B.1.5960.000697
ORF1ab/nsp3764Q764RcAacGa67B.10.000055
ORF1ab/nsp3764Q764RcAAcGG17B.10.000009
ORF1ab/nsp3764Q764RcAacGa66AY.1180.000376
ORF1ab/nsp3764Q764HcaAcaC56AY.30.00005
ORF1ab/nsp3764Q764HcaAcaT16AY.30.00001
ORF1ab/nsp3764Q764QcaAcaG66AY.4.20.00013
ORF1ab/nsp3764Q764HcaAcaC66AY.420.000241
ORF1ab/nsp3764Q764HcaAcaC66B.1.177.730.003398
ORF1ab/nsp3764Q764LcAacTa66B.1.20.000053
ORF1ab/nsp3764Q764LcAacTa55AY.40.000008
ORF1ab/nsp3764Q764HcaAcaT55AY.440.00003
ORF1ab/nsp3764Q764QcaAcaG55B.10.000046
ORF1ab/nsp3764Q764HcaAcaC55B.1.10.000091
ORF1ab/nsp3764Q764RcAacGa55B.1.2580.000333
ORF1ab/nsp3764Q764LcAacTa55P.10.000079
ORF1ab/nsp3764Q764PcAacCa44All0.000001
ORF1ab/nsp3764Q764ECaaGaa44All0.000001
ORF1ab/nsp3764Q764del1CAATG-14All0
ORF1ab/nsp3764Q764del1caAca-14All0
ORF1ab/nsp3764Q764del1Caa-aa14All0
ORF1ab/nsp3764Q764del1cAac-a14All0
ORF1ab/nsp3764Q764KCaaAaa44AY.4.50.00043
ORF1ab/nsp3764Q764RcAacGa44AY.420.000161
ORF1ab/nsp3764Q764HcaAcaC44AY.430.000018
ORF1ab/nsp3764Q764delCAA---44B.1.10.000073
ORF1ab/nsp3764Q764KCaaAaa44B.1.1.4330.005698
ORF1ab/nsp3764Q764KCaaAaa44B.1.1.70.000004
ORF1ab/nsp3764Q764LcAacTa44B.1.1.70.000004
ORF1ab/nsp3764Q764delCAA---44B.1.1770.000053
ORF1ab/nsp3764Q764RcAacGa44B.1.177.790.009368
ORF1ab/nsp3764Q764HcaAcaC44B.1.3490.002859
ORF1ab/nsp3764Q764HcaAcaC33AY.100.00159
ORF1ab/nsp3764Q764LcAacTa33AY.200.000117
ORF1ab/nsp3764Q764RcAacGa33AY.30.00003
ORF1ab/nsp3764Q764LcAacTa33AY.340.000291
ORF1ab/nsp3764Q764XCaaTaa33AY.40.000005
ORF1ab/nsp3764Q764LcAacTa33AY.4.20.000065
ORF1ab/nsp3764Q764QcaAcaG33AY.430.000013
ORF1ab/nsp3764Q764QcaAcaG33AY.440.000018
ORF1ab/nsp3764Q764RcAacGa33B.1.1.3110.001074
ORF1ab/nsp3764Q764RcAacGa33B.1.1770.00004
ORF1ab/nsp3764Q764ECaaGaa33B.1.3510.000089
ORF1ab/nsp3764Q764HcaAcaC33B.1.4000.001287
ORF1ab/nsp3764Q764HcaAcaC33B.1.4280.003061
ORF1ab/nsp3764Q764XCaaTaa33D.20.000225
ORF1ab/nsp3764Q764delCAA---220.111111
ORF1ab/nsp3764Q764QcaAcaG22A.10.000564
ORF1ab/nsp3764Q764del2CAAT--12All0
ORF1ab/nsp3764Q764del2cAAc--12All0
ORF1ab/nsp3764Q764KCaaAaa22AY.1030.000012
ORF1ab/nsp3764Q764HcaAcaC22AY.250.000012
ORF1ab/nsp3764Q764delCAA---22AY.250.000012
ORF1ab/nsp3764Q764QcaAcaG22AY.390.000049
ORF1ab/nsp3764Q764KCaaAaa22AY.390.000049
ORF1ab/nsp3764Q764delCAA---22AY.40.000003
ORF1ab/nsp3764Q764XCaaTaa22AY.440.000012
ORF1ab/nsp3764Q764KCaaAaa22AY.440.000012
ORF1ab/nsp3764Q764HcaAcaC22AY.750.000112
ORF1ab/nsp3764Q764RcAacGa22AY.90.000135
ORF1ab/nsp3764Q764HcaAcaC22AY.9.20.000073
ORF1ab/nsp3764Q764HcaAcaC22B0.000256
ORF1ab/nsp3764Q764XCaaTaa22B0.000256
ORF1ab/nsp3764Q764KCaaAaa22B.10.000018
ORF1ab/nsp3764Q764LcAacTa22B.10.000018
ORF1ab/nsp3764Q764HcaAcaC22B.1.1.480.005747
ORF1ab/nsp3764Q764QcaAcaG22B.1.1770.000026
ORF1ab/nsp3764Q764QcaAcaG22B.1.20.000018
ORF1ab/nsp3764Q764LcAacTa22B.1.2430.000139
ORF1ab/nsp3764Q764HcaAcaC22B.1.3240.00321
ORF1ab/nsp3764Q764delCAA---22B.1.360.000292
ORF1ab/nsp3764Q764QcaAcaG22B.1.4290.000047
ORF1ab/nsp3764Q764HcaAcaC22B.1.5950.000522
ORF1ab/nsp3764Q764RcAacGa22B.1.5960.000174
ORF1ab/nsp3764Q764LcAacTa22B.1.617.20.000008
ORF1ab/nsp3764Q764delCAA---22B.1.617.20.000008
ORF1ab/nsp3764Q764KCaaAaa22B.1.617.20.000008
ORF1ab/nsp3764Q764QcaAcaG22D.20.00015
ORF1ab/nsp3764Q764RcAacGa22P.10.000032
ORF1ab/nsp3764Q764LcAacTa22P.1.20.002312
ORF1ab/nsp3764Q764QcaAcaG22P.30.00319
ORF1ab/nsp3764Q764delCAA---11A0.000387
ORF1ab/nsp3764Q764delCAA---11A.2.20.001689
ORF1ab/nsp3764Q764QcaAcaG11A.2.40.003367
ORF1ab/nsp3764Q764HcaAcaC11A.2.40.003367
ORF1ab/nsp3764Q764RcAacGa11AE.80.000489
ORF1ab/nsp3764Q764GCAAGGG11All0
ORF1ab/nsp3764Q764LcAacTa11AY.1020.000027
ORF1ab/nsp3764Q764RcAacGa11AY.1030.000006
ORF1ab/nsp3764Q764delCAA---11AY.1110.000183
ORF1ab/nsp3764Q764RcAacGa11AY.230.00007
ORF1ab/nsp3764Q764XCaaTaa11AY.250.000006
ORF1ab/nsp3764Q764QcaAcaG11AY.250.000006
ORF1ab/nsp3764Q764QcaAcaG11AY.290.000016
ORF1ab/nsp3764Q764LcAacTa11AY.290.000016
ORF1ab/nsp3764Q764RcAacGa11AY.290.000016
ORF1ab/nsp3764Q764LcAacTa11AY.30.00001
ORF1ab/nsp3764Q764del2cAAc--11AY.30.00001
ORF1ab/nsp3764Q764HcaAcaT11AY.370.000316
ORF1ab/nsp3764Q764LcAacTa11AY.390.000025
ORF1ab/nsp3764Q764XCaaTaa11AY.390.000025
ORF1ab/nsp3764Q764RcAacGa11AY.39.10.00004
ORF1ab/nsp3764Q764delCAA---11AY.4.50.000107
ORF1ab/nsp3764Q764HcaAcaC11AY.4.50.000107
ORF1ab/nsp3764Q764KCaaAaa11AY.420.00004
ORF1ab/nsp3764Q764delCAA---11AY.430.000004
ORF1ab/nsp3764Q764RcAacGa11AY.430.000004
ORF1ab/nsp3764Q764PcAacCa11AY.440.000006
ORF1ab/nsp3764Q764HcaAcaC11AY.460.000104
ORF1ab/nsp3764Q764LcAacTa11AY.460.000104
ORF1ab/nsp3764Q764HcaAcaC11AY.46.50.000198
ORF1ab/nsp3764Q764XCaaTaa11AY.46.60.000072
ORF1ab/nsp3764Q764HcaAcaC11AY.470.000031
ORF1ab/nsp3764Q764LcAacTa11AY.470.000031
ORF1ab/nsp3764Q764RcAacGa11AY.470.000031
ORF1ab/nsp3764Q764RcAacGa11AY.60.000041
ORF1ab/nsp3764Q764QcaAcaG11AY.600.000938
ORF1ab/nsp3764Q764LcAacTa11AY.670.000464
ORF1ab/nsp3764Q764RcAacGa11AY.750.000056
ORF1ab/nsp3764Q764delCAA---11AY.75.10.00018
ORF1ab/nsp3764Q764del1Caa-aa11AY.90.000068
ORF1ab/nsp3764Q764RcAacGa11AY.9.20.000037
ORF1ab/nsp3764Q764KCaaAaa11AY.9.20.000037
ORF1ab/nsp3764Q764LcAacTa11AY.960.002075
ORF1ab/nsp3764Q764delCAA---11AY.99.10.001553
ORF1ab/nsp3764Q764GCAAGGG11B0.000128
ORF1ab/nsp3764Q764QcaAcaG11B.1.10.000018
ORF1ab/nsp3764Q764KCaaAaa11B.1.10.000018
ORF1ab/nsp3764Q764RcAacGa11B.1.10.000018
ORF1ab/nsp3764Q764delCAA---11B.1.1.1390.022727
ORF1ab/nsp3764Q764RcAacGa11B.1.1.140.017241
ORF1ab/nsp3764Q764delCAA---11B.1.1.1420.017544
ORF1ab/nsp3764Q764XCaaTaa11B.1.1.1740.003378
ORF1ab/nsp3764Q764delCAA---11B.1.1.2180.007692
ORF1ab/nsp3764Q764delCAA---11B.1.1.3150.008475
ORF1ab/nsp3764Q764delCAA---11B.1.1.370.000193
ORF1ab/nsp3764Q764HcaAcaC11B.1.1.4160.000905
ORF1ab/nsp3764Q764HcaAcaC11B.1.1.4500.034483
ORF1ab/nsp3764Q764QcaAcaG11B.1.1.4860.001577
ORF1ab/nsp3764Q764delCAA---11B.1.1.700.000341
ORF1ab/nsp3764Q764delCAA---11B.1.1400.018868
ORF1ab/nsp3764Q764HcaAcaC11B.1.1770.000013
ORF1ab/nsp3764Q764XCaaTaa11B.1.1770.000013
ORF1ab/nsp3764Q764RcAacGa11B.1.177.210.000076
ORF1ab/nsp3764Q764delCAA---11B.1.177.540.000606
ORF1ab/nsp3764Q764RcAacGa11B.1.177.600.000218
ORF1ab/nsp3764Q764delCAA---11B.1.177.620.001192
ORF1ab/nsp3764Q764delCAA---11B.1.177.630.002703
ORF1ab/nsp3764Q764HcaAcaC11B.1.177.650.000665
ORF1ab/nsp3764Q764delCAA---11B.1.177.680.015152
ORF1ab/nsp3764Q764RcAacGa11B.1.20.000009
ORF1ab/nsp3764Q764del1CAATG-11B.1.20.000009
ORF1ab/nsp3764Q764PcAacCa11B.1.20.000009
ORF1ab/nsp3764Q764XCaaTaa11B.1.20.000009
ORF1ab/nsp3764Q764HcaAcaC11B.1.2060.000816
ORF1ab/nsp3764Q764XCaaTaa11B.1.2060.000816
ORF1ab/nsp3764Q764HcaAcaC11B.1.2340.000132
ORF1ab/nsp3764Q764HcaAcaC11B.1.2410.000812
ORF1ab/nsp3764Q764XCaaTaa11B.1.2430.00007
ORF1ab/nsp3764Q764RcAacGa11B.1.2430.00007
ORF1ab/nsp3764Q764HcaAcaC11B.1.2650.001271
ORF1ab/nsp3764Q764del1cAac-a11B.1.2650.001271
ORF1ab/nsp3764Q764HcaAcaC11B.1.2930.0125
ORF1ab/nsp3764Q764QcaAcaG11B.1.3110.000275
ORF1ab/nsp3764Q764delCAA---11B.1.3190.003049
ORF1ab/nsp3764Q764LcAacTa11B.1.3510.00003
ORF1ab/nsp3764Q764RcAacGa11B.1.36.160.001425
ORF1ab/nsp3764Q764delCAA---11B.1.36.180.00042
ORF1ab/nsp3764Q764QcaAcaG11B.1.36.180.00042
ORF1ab/nsp3764Q764XCaaTaa11B.1.3750.00082
ORF1ab/nsp3764Q764XCaaTaa11B.1.3960.000706
ORF1ab/nsp3764Q764delCAA---11B.1.4090.000781
ORF1ab/nsp3764Q764delCAA---11B.1.4150.014286
ORF1ab/nsp3764Q764HcaAcaC11B.1.4270.00005
ORF1ab/nsp3764Q764PcAacCa11B.1.4290.000024
ORF1ab/nsp3764Q764HcaAcaC11B.1.4290.000024
ORF1ab/nsp3764Q764HcaAcaC11B.1.4530.003236
ORF1ab/nsp3764Q764RcAacGa11B.1.466.20.000391
ORF1ab/nsp3764Q764XCaaTaa11B.1.5260.000024
ORF1ab/nsp3764Q764HcaAcaC11B.1.5580.004566
ORF1ab/nsp3764Q764XCaaTaa11B.1.5730.006098
ORF1ab/nsp3764Q764HcaAcaC11B.1.5820.000491
ORF1ab/nsp3764Q764XCaaTaa11B.1.5820.000491
ORF1ab/nsp3764Q764delCAA---11B.1.5960.000087
ORF1ab/nsp3764Q764RcAacGa11B.1.6000.005848
ORF1ab/nsp3764Q764HcaAcaC11B.1.6020.006536
ORF1ab/nsp3764Q764XCaaTaa11B.1.6060.006024
ORF1ab/nsp3764Q764HcaAcaC11B.1.6090.000479
ORF1ab/nsp3764Q764RcAacGa11B.1.6090.000479
ORF1ab/nsp3764Q764HcaAcaC11B.1.6120.002653
ORF1ab/nsp3764Q764delCAA---11B.1.617.10.000129
ORF1ab/nsp3764Q764QcaAcaG11B.1.617.10.000129
ORF1ab/nsp3764Q764HcaAcaC11B.1.617.20.000004
ORF1ab/nsp3764Q764ECaaGaa11B.1.617.20.000004
ORF1ab/nsp3764Q764XCaaTaa11B.1.617.20.000004
ORF1ab/nsp3764Q764del2CAAT--11B.1.617.20.000004
ORF1ab/nsp3764Q764del1caAca-11B.1.6210.000089
ORF1ab/nsp3764Q764RcAacGa11B.1.6370.000073
ORF1ab/nsp3764Q764delCAA---11B.150.017544
ORF1ab/nsp3764Q764delCAA---11C.370.000116
ORF1ab/nsp3764Q764LcAacTa11D.20.000075
ORF1ab/nsp3764Q764PcAacCa11P.10.000016
ORF1ab/nsp3764Q764QcaAcaG11Q.10.000126
ORF1ab/nsp3764Q764HcaAcaC11Q.80.000165
ORF1ab/nsp3764Q764HcaAcaC11W.40.001351

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.