CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 752

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3752V752VV1570VsyngtGgtA755462180.823144973-4975
ORF1ab/nsp3752V752VV1570VsyngtGgtT755413310.1761984973-4975
ORF1ab/nsp3752V752VV1570VsyngtGgtC755450.0006619014973-4975
ORF1ab/nsp3752V752LV1570LnonsynGtgTtg2272170.9559474973-4975
ORF1ab/nsp3752V752LV1570LnonsynGtgCtg227100.04405294973-4975
ORF1ab/nsp3752V752IV1570InonsynGtGAtA1061050.9905664973-4975
ORF1ab/nsp3752V752IV1570InonsynGtGAtT10610.009433964973-4975
ORF1ab/nsp3752V752MV1570MnonsynGtgAtg575714973-4975
ORF1ab/nsp3752V752delV1570deldelGTG---393914973-4975
ORF1ab/nsp3752V752AV1570AnonsyngTggCg353514973-4975
ORF1ab/nsp3752V752GV1570GnonsyngTggGg19180.9473684973-4975
ORF1ab/nsp3752V752GV1570GnonsyngTGgGT1910.05263164973-4975
ORF1ab/nsp3752V752EV1570EnonsyngTggAg3314973-4975
ORF1ab/nsp3752V752del1V1570del1delGtGAt-3314973-4975
ORF1ab/nsp3752V752RV1570RnonsynGTgAGg2214973-4975
ORF1ab/nsp3752V752del2V1570del2delgTGg--210.54973-4975
ORF1ab/nsp3752V752del2V1570del2delGTg--g210.54973-4975
ORF1ab/nsp3752V752SV1570SnonsynGTGAGT1114973-4975

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3752V752VgtGgtA62187554All0.001189
ORF1ab/nsp3752V752VgtGgtT13317554All0.000255
ORF1ab/nsp3752V752VgtGgtC57554All0.000001
ORF1ab/nsp3752V752VgtGgtA57405741AY.46.60.41447
ORF1ab/nsp3752V752VgtGgtT15741AY.46.60.000072
ORF1ab/nsp3752V752VgtGgtT459606B.1.1.70.000411
ORF1ab/nsp3752V752VgtGgtA145606B.1.1.70.00013
ORF1ab/nsp3752V752VgtGgtC2606B.1.1.70.000002
ORF1ab/nsp3752V752VgtGgtT376376B.1.3510.011177
ORF1ab/nsp3752V752LGtgTtg217227All0.000042
ORF1ab/nsp3752V752LGtgCtg10227All0.000002
ORF1ab/nsp3752V752VgtGgtT161202AY.40.000251
ORF1ab/nsp3752V752VgtGgtA41202AY.40.000064
ORF1ab/nsp3752V752LGtgTtg107107AY.40.000167
ORF1ab/nsp3752V752IGtGAtA105106All0.00002
ORF1ab/nsp3752V752IGtGAtT1106All0
ORF1ab/nsp3752V752IGtGAtA105105AY.46.60.007582
ORF1ab/nsp3752V752VgtGgtT5296B.1.617.20.000196
ORF1ab/nsp3752V752VgtGgtA4396B.1.617.20.000162
ORF1ab/nsp3752V752VgtGgtC196B.1.617.20.000004
ORF1ab/nsp3752V752VgtGgtA3964AY.1030.000242
ORF1ab/nsp3752V752VgtGgtT2564AY.1030.000155
ORF1ab/nsp3752V752MGtgAtg5757All0.000011
ORF1ab/nsp3752V752VgtGgtT5656B.1.36.290.028971
ORF1ab/nsp3752V752VgtGgtA4547AY.440.000274
ORF1ab/nsp3752V752VgtGgtT247AY.440.000012
ORF1ab/nsp3752V752delGTG---3939All0.000007
ORF1ab/nsp3752V752AgTggCg3535All0.000007
ORF1ab/nsp3752V752VgtGgtA2032B.1.20.000176
ORF1ab/nsp3752V752VgtGgtT1232B.1.20.000106
ORF1ab/nsp3752V752VgtGgtA1425AY.430.000062
ORF1ab/nsp3752V752VgtGgtT1125AY.430.000049
ORF1ab/nsp3752V752VgtGgtA2323AY.300.009102
ORF1ab/nsp3752V752LGtgTtg1622B.1.1.70.000014
ORF1ab/nsp3752V752LGtgCtg622B.1.1.70.000005
ORF1ab/nsp3752V752GgTggGg1819All0.000003
ORF1ab/nsp3752V752GgTGgGT119All0
ORF1ab/nsp3752V752VgtGgtT1919B.1.380.612903
ORF1ab/nsp3752V752delGTG---1717B.1.1.70.000015
ORF1ab/nsp3752V752VgtGgtT1616P.10.000252
ORF1ab/nsp3752V752VgtGgtA1313AY.960.026971
ORF1ab/nsp3752V752VgtGgtA1111AY.1190.000388
ORF1ab/nsp3752V752AgTggCg1111B.1.20.000097
ORF1ab/nsp3752V752LGtgTtg1010AY.470.000311
ORF1ab/nsp3752V752VgtGgtT510B.10.000046
ORF1ab/nsp3752V752VgtGgtA410B.10.000037
ORF1ab/nsp3752V752VgtGgtC110B.10.000009
ORF1ab/nsp3752V752VgtGgtT1010B.1.1.2840.001074
ORF1ab/nsp3752V752LGtgTtg1010B.1.617.20.000038
ORF1ab/nsp3752V752MGtgAtg99B.1.1770.000119
ORF1ab/nsp3752V752LGtgTtg99B.1.20.000079
ORF1ab/nsp3752V752VgtGgtT99B.1.6370.000658
ORF1ab/nsp3752V752LGtgTtg88AY.4.20.000174
ORF1ab/nsp3752V752VgtGgtA88AY.460.000833
ORF1ab/nsp3752V752VgtGgtT88AY.9.20.000294
ORF1ab/nsp3752V752VgtGgtT88B.1.1.2970.017897
ORF1ab/nsp3752V752MGtgAtg88B.1.1.70.000007
ORF1ab/nsp3752V752VgtGgtA88B.1.258.170.000832
ORF1ab/nsp3752V752VgtGgtA47AY.39.10.000158
ORF1ab/nsp3752V752VgtGgtT37AY.39.10.000119
ORF1ab/nsp3752V752LGtgTtg77B.1.10.000127
ORF1ab/nsp3752V752AgTggCg77B.1.1.330.002946
ORF1ab/nsp3752V752VgtGgtT77Q.80.001154
ORF1ab/nsp3752V752VgtGgtT56AY.30.00005
ORF1ab/nsp3752V752VgtGgtA16AY.30.00001
ORF1ab/nsp3752V752VgtGgtT56AY.450.000608
ORF1ab/nsp3752V752VgtGgtA16AY.450.000122
ORF1ab/nsp3752V752VgtGgtA66AY.920.001724
ORF1ab/nsp3752V752VgtGgtT46B.1.1.5190.000159
ORF1ab/nsp3752V752VgtGgtA26B.1.1.5190.000079
ORF1ab/nsp3752V752VgtGgtT45AY.250.000024
ORF1ab/nsp3752V752VgtGgtA15AY.250.000006
ORF1ab/nsp3752V752VgtGgtA35AY.390.000074
ORF1ab/nsp3752V752VgtGgtT25AY.390.000049
ORF1ab/nsp3752V752LGtgTtg55AY.430.000022
ORF1ab/nsp3752V752VgtGgtA55AY.740.000578
ORF1ab/nsp3752V752MGtgAtg55B.1.3510.000149
ORF1ab/nsp3752V752MGtgAtg55B.1.4290.000118
ORF1ab/nsp3752V752VgtGgtT55B.1.5260.000118
ORF1ab/nsp3752V752MGtgAtg44AY.40.000006
ORF1ab/nsp3752V752MGtgAtg44AY.440.000024
ORF1ab/nsp3752V752VgtGgtT34AY.50.000062
ORF1ab/nsp3752V752VgtGgtA14AY.50.000021
ORF1ab/nsp3752V752VgtGgtT44AY.98.10.000194
ORF1ab/nsp3752V752MGtgAtg44B.10.000037
ORF1ab/nsp3752V752VgtGgtT24B.1.10.000036
ORF1ab/nsp3752V752VgtGgtA24B.1.10.000036
ORF1ab/nsp3752V752VgtGgtT44B.1.360.000584
ORF1ab/nsp3752V752VgtGgtT44B.1.5250.000453
ORF1ab/nsp3752V752MGtgAtg44P.10.000063
ORF1ab/nsp3752V752VgtGgtA44P.1.150.000929
ORF1ab/nsp3752V752VgtGgtT44P.1.170.000647
ORF1ab/nsp3752V752del1GtGAt-33All0.000001
ORF1ab/nsp3752V752EgTggAg33All0.000001
ORF1ab/nsp3752V752VgtGgtA33AY.1000.000138
ORF1ab/nsp3752V752VgtGgtA23AY.1020.000053
ORF1ab/nsp3752V752VgtGgtT13AY.1020.000027
ORF1ab/nsp3752V752LGtgTtg33AY.1030.000019
ORF1ab/nsp3752V752VgtGgtT23AY.230.000139
ORF1ab/nsp3752V752VgtGgtA13AY.230.00007
ORF1ab/nsp3752V752VgtGgtT23AY.330.000134
ORF1ab/nsp3752V752VgtGgtA13AY.330.000067
ORF1ab/nsp3752V752LGtgTtg33AY.390.000074
ORF1ab/nsp3752V752VgtGgtA33AY.4.20.000065
ORF1ab/nsp3752V752VgtGgtA33AY.900.002053
ORF1ab/nsp3752V752GgTggGg33B.10.000027
ORF1ab/nsp3752V752AgTggCg33B.1.1.250.001706
ORF1ab/nsp3752V752AgTggCg33B.1.1.70.000003
ORF1ab/nsp3752V752del1GtGAt-33B.1.1.70.000003
ORF1ab/nsp3752V752LGtgTtg33B.1.1770.00004
ORF1ab/nsp3752V752VgtGgtT23B.1.617.10.000258
ORF1ab/nsp3752V752VgtGgtA13B.1.617.10.000129
ORF1ab/nsp3752V752LGtgCtg220.111111
ORF1ab/nsp3752V752GgTGgGT120.055556
ORF1ab/nsp3752V752GgTggGg120.055556
ORF1ab/nsp3752V752RGTgAGg22All0
ORF1ab/nsp3752V752del2GTg--g12All0
ORF1ab/nsp3752V752del2gTGg--12All0
ORF1ab/nsp3752V752VgtGgtT22AY.1130.000285
ORF1ab/nsp3752V752VgtGgtT12AY.1170.000085
ORF1ab/nsp3752V752VgtGgtA12AY.1170.000085
ORF1ab/nsp3752V752VgtGgtT22AY.1200.000074
ORF1ab/nsp3752V752MGtgAtg22AY.250.000012
ORF1ab/nsp3752V752VgtGgtT22AY.410.000588
ORF1ab/nsp3752V752LGtgTtg22AY.420.00008
ORF1ab/nsp3752V752LGtgTtg22AY.46.60.000144
ORF1ab/nsp3752V752VgtGgtT22AY.470.000062
ORF1ab/nsp3752V752VgtGgtA22AY.850.000854
ORF1ab/nsp3752V752LGtgTtg22B.10.000018
ORF1ab/nsp3752V752VgtGgtT22B.1.1.4580.083333
ORF1ab/nsp3752V752GgTggGg22B.1.1.5190.000079
ORF1ab/nsp3752V752GgTggGg22B.1.1.70.000002
ORF1ab/nsp3752V752LGtgTtg22B.1.1040.00738
ORF1ab/nsp3752V752delGTG---22B.1.1770.000026
ORF1ab/nsp3752V752VgtGgtA22B.1.2430.000139
ORF1ab/nsp3752V752VgtGgtT22B.1.2470.029851
ORF1ab/nsp3752V752VgtGgtT22B.1.351.10.076923
ORF1ab/nsp3752V752delGTG---22B.1.360.000292
ORF1ab/nsp3752V752GgTggGg22B.1.4290.000047
ORF1ab/nsp3752V752VgtGgtT12B.1.4290.000024
ORF1ab/nsp3752V752VgtGgtA12B.1.4290.000024
ORF1ab/nsp3752V752VgtGgtT22B.1.5680.002222
ORF1ab/nsp3752V752LGtgTtg22P.10.000032
ORF1ab/nsp3752V752EgTggAg110.055556
ORF1ab/nsp3752V752IGtGAtT110.055556
ORF1ab/nsp3752V752SGTGAGT110.055556
ORF1ab/nsp3752V752RGTgAGg110.055556
ORF1ab/nsp3752V752MGtgAtg110.055556
ORF1ab/nsp3752V752VgtGgtT110.055556
ORF1ab/nsp3752V752delGTG---11A0.000387
ORF1ab/nsp3752V752delGTG---11A.2.20.001689
ORF1ab/nsp3752V752SGTGAGT11All0
ORF1ab/nsp3752V752LGtgTtg11AY.1000.000046
ORF1ab/nsp3752V752LGtgTtg11AY.1020.000027
ORF1ab/nsp3752V752EgTggAg11AY.1030.000006
ORF1ab/nsp3752V752MGtgAtg11AY.1030.000006
ORF1ab/nsp3752V752VgtGgtT11AY.1060.000335
ORF1ab/nsp3752V752AgTggCg11AY.1170.000085
ORF1ab/nsp3752V752LGtgTtg11AY.1200.000037
ORF1ab/nsp3752V752MGtgAtg11AY.1200.000037
ORF1ab/nsp3752V752VgtGgtT11AY.20.000356
ORF1ab/nsp3752V752LGtgTtg11AY.200.000039
ORF1ab/nsp3752V752VgtGgtA11AY.220.002092
ORF1ab/nsp3752V752LGtgTtg11AY.240.000431
ORF1ab/nsp3752V752MGtgAtg11AY.30.00001
ORF1ab/nsp3752V752LGtgTtg11AY.330.000067
ORF1ab/nsp3752V752LGtgTtg11AY.39.10.00004
ORF1ab/nsp3752V752delGTG---11AY.40.000002
ORF1ab/nsp3752V752AgTggCg11AY.40.000002
ORF1ab/nsp3752V752VgtGgtA11AY.420.00004
ORF1ab/nsp3752V752LGtgTtg11AY.440.000006
ORF1ab/nsp3752V752VgtGgtA11AY.46.10.001027
ORF1ab/nsp3752V752LGtgTtg11AY.480.000465
ORF1ab/nsp3752V752VgtGgtT11AY.570.000656
ORF1ab/nsp3752V752VgtGgtT11AY.60.000041
ORF1ab/nsp3752V752MGtgAtg11AY.60.000041
ORF1ab/nsp3752V752AgTggCg11AY.610.000105
ORF1ab/nsp3752V752VgtGgtT11AY.610.000105
ORF1ab/nsp3752V752EgTggAg11AY.620.000436
ORF1ab/nsp3752V752VgtGgtA11AY.620.000436
ORF1ab/nsp3752V752LGtgTtg11AY.620.000436
ORF1ab/nsp3752V752VgtGgtA11AY.7.10.000113
ORF1ab/nsp3752V752LGtgTtg11AY.740.000116
ORF1ab/nsp3752V752VgtGgtT11AY.770.001127
ORF1ab/nsp3752V752VgtGgtT11AY.780.001541
ORF1ab/nsp3752V752VgtGgtA11AY.880.000884
ORF1ab/nsp3752V752MGtgAtg11AY.920.000287
ORF1ab/nsp3752V752VgtGgtA11AY.930.000273
ORF1ab/nsp3752V752LGtgTtg11AY.980.000079
ORF1ab/nsp3752V752VgtGgtA11AY.99.20.000092
ORF1ab/nsp3752V752AgTggCg11AY.99.20.000092
ORF1ab/nsp3752V752LGtgTtg11B0.000128
ORF1ab/nsp3752V752VgtGgtA11B0.000128
ORF1ab/nsp3752V752del2gTGg--11B.10.000009
ORF1ab/nsp3752V752RGTgAGg11B.10.000009
ORF1ab/nsp3752V752AgTggCg11B.10.000009
ORF1ab/nsp3752V752MGtgAtg11B.1.10.000018
ORF1ab/nsp3752V752AgTggCg11B.1.10.000018
ORF1ab/nsp3752V752VgtGgtT11B.1.1.1010.01
ORF1ab/nsp3752V752delGTG---11B.1.1.1390.022727
ORF1ab/nsp3752V752delGTG---11B.1.1.1420.017544
ORF1ab/nsp3752V752GgTggGg11B.1.1.2200.001859
ORF1ab/nsp3752V752MGtgAtg11B.1.1.2510.007937
ORF1ab/nsp3752V752VgtGgtA11B.1.1.2940.001266
ORF1ab/nsp3752V752VgtGgtT11B.1.1.3040.002809
ORF1ab/nsp3752V752VgtGgtT11B.1.1.3060.000438
ORF1ab/nsp3752V752VgtGgtT11B.1.1.4130.006897
ORF1ab/nsp3752V752LGtgTtg11B.1.1.440.00241
ORF1ab/nsp3752V752LGtgTtg11B.1.1470.000756
ORF1ab/nsp3752V752delGTG---11B.1.1570.002985
ORF1ab/nsp3752V752VgtGgtT11B.1.1600.000031
ORF1ab/nsp3752V752delGTG---11B.1.1600.000031
ORF1ab/nsp3752V752LGtgCtg11B.1.1600.000031
ORF1ab/nsp3752V752VgtGgtT11B.1.1770.000013
ORF1ab/nsp3752V752VgtGgtA11B.1.177.210.000076
ORF1ab/nsp3752V752delGTG---11B.1.177.540.000606
ORF1ab/nsp3752V752delGTG---11B.1.177.630.002703
ORF1ab/nsp3752V752AgTggCg11B.1.177.870.000728
ORF1ab/nsp3752V752MGtgAtg11B.1.20.000009
ORF1ab/nsp3752V752delGTG---11B.1.20.000009
ORF1ab/nsp3752V752GgTggGg11B.1.20.000009
ORF1ab/nsp3752V752VgtGgtA11B.1.2210.000071
ORF1ab/nsp3752V752GgTggGg11B.1.2320.000537
ORF1ab/nsp3752V752LGtgTtg11B.1.2360.002053
ORF1ab/nsp3752V752GgTggGg11B.1.2430.00007
ORF1ab/nsp3752V752LGtgTtg11B.1.3050.002151
ORF1ab/nsp3752V752LGtgTtg11B.1.3110.000275
ORF1ab/nsp3752V752del2GTg--g11B.1.3110.000275
ORF1ab/nsp3752V752delGTG---11B.1.3190.003049
ORF1ab/nsp3752V752VgtGgtC11B.1.3320.003497
ORF1ab/nsp3752V752VgtGgtT11B.1.3330.010526
ORF1ab/nsp3752V752AgTggCg11B.1.3490.000715
ORF1ab/nsp3752V752VgtGgtT11B.1.36.350.002604
ORF1ab/nsp3752V752delGTG---11B.1.4090.000781
ORF1ab/nsp3752V752delGTG---11B.1.4150.014286
ORF1ab/nsp3752V752MGtgAtg11B.1.4160.001269
ORF1ab/nsp3752V752VgtGgtT11B.1.4270.00005
ORF1ab/nsp3752V752GgTggGg11B.1.4270.00005
ORF1ab/nsp3752V752LGtgTtg11B.1.4290.000024
ORF1ab/nsp3752V752GgTggGg11B.1.5100.026316
ORF1ab/nsp3752V752GgTggGg11B.1.5610.000397
ORF1ab/nsp3752V752LGtgTtg11B.1.5740.002151
ORF1ab/nsp3752V752VgtGgtT11B.1.5760.000907
ORF1ab/nsp3752V752VgtGgtA11B.1.5960.000087
ORF1ab/nsp3752V752LGtgTtg11B.1.5960.000087
ORF1ab/nsp3752V752LGtgTtg11B.1.617.10.000129
ORF1ab/nsp3752V752delGTG---11B.1.617.10.000129
ORF1ab/nsp3752V752delGTG---11B.1.617.20.000004
ORF1ab/nsp3752V752MGtgAtg11B.1.617.20.000004
ORF1ab/nsp3752V752AgTggCg11B.1.617.20.000004
ORF1ab/nsp3752V752delGTG---11B.1.6210.000089
ORF1ab/nsp3752V752LGtgCtg11B.1.6250.002353
ORF1ab/nsp3752V752LGtgTtg11B.1.6280.000352
ORF1ab/nsp3752V752delGTG---11B.150.017544
ORF1ab/nsp3752V752LGtgTtg11B.400.000364
ORF1ab/nsp3752V752VgtGgtT11B.550.00295
ORF1ab/nsp3752V752LGtgTtg11B.60.00091
ORF1ab/nsp3752V752GgTggGg11C.390.018868
ORF1ab/nsp3752V752LGtgTtg11D.20.000075
ORF1ab/nsp3752V752delGTG---11P.10.000016
ORF1ab/nsp3752V752AgTggCg11P.10.000016
ORF1ab/nsp3752V752MGtgAtg11P.1.10.000318
ORF1ab/nsp3752V752VgtGgtA11P.1.140.000048
ORF1ab/nsp3752V752AgTggCg11P.1.140.000048
ORF1ab/nsp3752V752VgtGgtT11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.