CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 737

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3737N737DN1555DnonsynAatGat387738750.9994844928-4930
ORF1ab/nsp3737N737DN1555DnonsynAaTGaC387720.0005158634928-4930
ORF1ab/nsp3737N737NN1555NsynaaTaaC1360136014928-4930
ORF1ab/nsp3737N737SN1555SnonsynaAtaGt1731710.9884394928-4930
ORF1ab/nsp3737N737SN1555SnonsynaATaGC17320.01156074928-4930
ORF1ab/nsp3737N737TN1555TnonsynaAtaCt1401370.9785714928-4930
ORF1ab/nsp3737N737TN1555TnonsynaATaCC14030.02142864928-4930
ORF1ab/nsp3737N737delN1555deldelAAT---616114928-4930
ORF1ab/nsp3737N737YN1555YnonsynAatTat24220.9166674928-4930
ORF1ab/nsp3737N737YN1555YnonsynAaTTaC2420.08333334928-4930
ORF1ab/nsp3737N737KN1555KnonsynaaTaaG23210.9130434928-4930
ORF1ab/nsp3737N737KN1555KnonsynaaTaaA2320.08695654928-4930
ORF1ab/nsp3737N737VN1555VnonsynAATGTC730.4285714928-4930
ORF1ab/nsp3737N737VN1555VnonsynAATGTA720.2857144928-4930
ORF1ab/nsp3737N737VN1555VnonsynAAtGTt720.2857144928-4930
ORF1ab/nsp3737N737HN1555HnonsynAatCat540.84928-4930
ORF1ab/nsp3737N737HN1555HnonsynAaTCaC510.24928-4930
ORF1ab/nsp3737N737FN1555FnonsynAAtTTt420.54928-4930
ORF1ab/nsp3737N737FN1555FnonsynAATTTC420.54928-4930
ORF1ab/nsp3737N737EN1555EnonsynAaTGaA3314928-4930
ORF1ab/nsp3737N737XN1555XnonsynAaTTaA3314928-4930
ORF1ab/nsp3737N737RN1555RnonsynAAtCGt320.6666674928-4930
ORF1ab/nsp3737N737RN1555RnonsynaATaGA310.3333334928-4930
ORF1ab/nsp3737N737LN1555LnonsynAATTTA2214928-4930
ORF1ab/nsp3737N737GN1555GnonsynAATGGA210.54928-4930
ORF1ab/nsp3737N737PN1555PnonsynAAtCCt210.54928-4930
ORF1ab/nsp3737N737PN1555PnonsynAATCCC210.54928-4930
ORF1ab/nsp3737N737GN1555GnonsynAAtGGt210.54928-4930
ORF1ab/nsp3737N737CN1555CnonsynAAtTGt1114928-4930
ORF1ab/nsp3737N737del1N1555del1delAat-at1114928-4930
ORF1ab/nsp3737N737IN1555InonsynaAtaTt1114928-4930

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3737N737DAatGat38753877All0.000741
ORF1ab/nsp3737N737DAaTGaC23877All0
ORF1ab/nsp3737N737DAatGat35373537AY.60.145472
ORF1ab/nsp3737N737NaaTaaC13601360All0.00026
ORF1ab/nsp3737N737NaaTaaC10751075AY.40.001673
ORF1ab/nsp3737N737SaAtaGt171173All0.000033
ORF1ab/nsp3737N737SaATaGC2173All0
ORF1ab/nsp3737N737TaAtaCt137140All0.000026
ORF1ab/nsp3737N737TaATaCC3140All0.000001
ORF1ab/nsp3737N737DAatGat127127B.1.617.20.000478
ORF1ab/nsp3737N737TaAtaCt8282AY.4.30.069024
ORF1ab/nsp3737N737DAatGat6868AY.30.000676
ORF1ab/nsp3737N737NaaTaaC6363B.1.1770.00083
ORF1ab/nsp3737N737delAAT---6161All0.000012
ORF1ab/nsp3737N737SaAtaGt4545B.1.177.590.725806
ORF1ab/nsp3737N737TaAtaCt4343B.1.177.70.007089
ORF1ab/nsp3737N737SaAtaGt4141B.1.1.70.000037
ORF1ab/nsp3737N737NaaTaaC3131B.1.1.70.000028
ORF1ab/nsp3737N737DAatGat2626AY.50.000537
ORF1ab/nsp3737N737YAatTat2224All0.000004
ORF1ab/nsp3737N737YAaTTaC224All0
ORF1ab/nsp3737N737delAAT---2424B.1.1.70.000021
ORF1ab/nsp3737N737KaaTaaG2123All0.000004
ORF1ab/nsp3737N737KaaTaaA223All0
ORF1ab/nsp3737N737NaaTaaC2121B.1.1.5280.100962
ORF1ab/nsp3737N737NaaTaaC1919AY.430.000084
ORF1ab/nsp3737N737DAatGat1919B.1.1.70.000017
ORF1ab/nsp3737N737SaAtaGt1818AY.250.000108
ORF1ab/nsp3737N737NaaTaaC1717B.1.617.20.000064
ORF1ab/nsp3737N737DAatGat1515AY.420.000603
ORF1ab/nsp3737N737DAatGat1414AY.40.000022
ORF1ab/nsp3737N737SaAtaGt1414B.1.177.600.003058
ORF1ab/nsp3737N737DAatGat1111AY.430.000049
ORF1ab/nsp3737N737NaaTaaC1111AY.46.50.002183
ORF1ab/nsp3737N737NaaTaaC1010N.60.070922
ORF1ab/nsp3737N737NaaTaaC99AY.250.000054
ORF1ab/nsp3737N737NaaTaaC99B.1.3670.007132
ORF1ab/nsp3737N737KaaTaaG88AY.260.000226
ORF1ab/nsp3737N737VAATGTC37All0.000001
ORF1ab/nsp3737N737VAATGTA27All0
ORF1ab/nsp3737N737VAAtGTt27All0
ORF1ab/nsp3737N737NaaTaaC77AY.1030.000043
ORF1ab/nsp3737N737VAAtGTt260.111111
ORF1ab/nsp3737N737VAATGTC260.111111
ORF1ab/nsp3737N737VAATGTA260.111111
ORF1ab/nsp3737N737SaAtaGt66AY.430.000027
ORF1ab/nsp3737N737SaAtaGt66P.10.000095
ORF1ab/nsp3737N737DAatGat66P.10.000095
ORF1ab/nsp3737N737HAatCat45All0.000001
ORF1ab/nsp3737N737HAaTCaC15All0
ORF1ab/nsp3737N737DAatGat55AY.440.00003
ORF1ab/nsp3737N737NaaTaaC55B.10.000046
ORF1ab/nsp3737N737NaaTaaC55B.1.5260.000118
ORF1ab/nsp3737N737NaaTaaC55P.1.150.001162
ORF1ab/nsp3737N737FAATTTC240.111111
ORF1ab/nsp3737N737FAAtTTt240.111111
ORF1ab/nsp3737N737FAAtTTt24All0
ORF1ab/nsp3737N737FAATTTC24All0
ORF1ab/nsp3737N737NaaTaaC44AY.440.000024
ORF1ab/nsp3737N737DAatGat44AY.580.00363
ORF1ab/nsp3737N737SaAtaGt44AY.750.000224
ORF1ab/nsp3737N737SaAtaGt44AY.9.10.000335
ORF1ab/nsp3737N737SaAtaGt34B.10.000027
ORF1ab/nsp3737N737SaATaGC14B.10.000009
ORF1ab/nsp3737N737NaaTaaC44B.1.1.340.052632
ORF1ab/nsp3737N737NaaTaaC44B.1.1.5190.000159
ORF1ab/nsp3737N737YAatTat44B.1.1.70.000004
ORF1ab/nsp3737N737delAAT---44B.1.1770.000053
ORF1ab/nsp3737N737XAaTTaA33All0.000001
ORF1ab/nsp3737N737EAaTGaA33All0.000001
ORF1ab/nsp3737N737RAAtCGt23All0
ORF1ab/nsp3737N737RaATaGA13All0
ORF1ab/nsp3737N737DAatGat33AY.1060.001005
ORF1ab/nsp3737N737TaAtaCt33AY.260.000085
ORF1ab/nsp3737N737NaaTaaC33AY.290.000047
ORF1ab/nsp3737N737delAAT---33AY.430.000013
ORF1ab/nsp3737N737DAatGat33AY.670.001393
ORF1ab/nsp3737N737SaAtaGt33B.1.10.000054
ORF1ab/nsp3737N737DAatGat33B.1.10.000054
ORF1ab/nsp3737N737NaaTaaC33B.1.1.390.001529
ORF1ab/nsp3737N737KaaTaaG33B.1.1.70.000003
ORF1ab/nsp3737N737NaaTaaC33B.1.177.810.000568
ORF1ab/nsp3737N737NaaTaaC33B.1.2210.000213
ORF1ab/nsp3737N737NaaTaaC33B.1.36.70.012
ORF1ab/nsp3737N737YAatTat33B.1.617.20.000011
ORF1ab/nsp3737N737NaaTaaC33P.10.000047
ORF1ab/nsp3737N737LAATTTA220.111111
ORF1ab/nsp3737N737XAaTTaA220.111111
ORF1ab/nsp3737N737YAaTTaC220.111111
ORF1ab/nsp3737N737EAaTGaA220.111111
ORF1ab/nsp3737N737DAaTGaC220.111111
ORF1ab/nsp3737N737NaaTaaC22A.2.30.009479
ORF1ab/nsp3737N737NaaTaaC22A.2.50.000998
ORF1ab/nsp3737N737LAATTTA22All0
ORF1ab/nsp3737N737PAAtCCt12All0
ORF1ab/nsp3737N737PAATCCC12All0
ORF1ab/nsp3737N737GAAtGGt12All0
ORF1ab/nsp3737N737GAATGGA12All0
ORF1ab/nsp3737N737NaaTaaC22AY.1000.000092
ORF1ab/nsp3737N737DAatGat22AY.1080.002205
ORF1ab/nsp3737N737DAatGat22AY.1110.000366
ORF1ab/nsp3737N737YAatTat22AY.116.10.000623
ORF1ab/nsp3737N737YAatTat22AY.250.000012
ORF1ab/nsp3737N737DAatGat22AY.390.000049
ORF1ab/nsp3737N737SaAtaGt22AY.390.000049
ORF1ab/nsp3737N737delAAT---22AY.40.000003
ORF1ab/nsp3737N737TaAtaCt22AY.40.000003
ORF1ab/nsp3737N737SaAtaGt22AY.40.000003
ORF1ab/nsp3737N737NaaTaaC22AY.46.40.000329
ORF1ab/nsp3737N737DAatGat22AY.470.000062
ORF1ab/nsp3737N737SaAtaGt22AY.470.000062
ORF1ab/nsp3737N737NaaTaaC22AY.50.000041
ORF1ab/nsp3737N737YAatTat22AY.98.10.000097
ORF1ab/nsp3737N737HAatCat12B.10.000009
ORF1ab/nsp3737N737HAaTCaC12B.10.000009
ORF1ab/nsp3737N737PAATCCC12B.10.000009
ORF1ab/nsp3737N737PAAtCCt12B.10.000009
ORF1ab/nsp3737N737NaaTaaC22B.1.10.000036
ORF1ab/nsp3737N737GAATGGA12B.1.10.000018
ORF1ab/nsp3737N737GAAtGGt12B.1.10.000018
ORF1ab/nsp3737N737NaaTaaC22B.1.1.370.000386
ORF1ab/nsp3737N737RAAtCGt22B.1.1.70.000002
ORF1ab/nsp3737N737NaaTaaC22B.1.20.000018
ORF1ab/nsp3737N737NaaTaaC22B.1.3510.000059
ORF1ab/nsp3737N737delAAT---22B.1.360.000292
ORF1ab/nsp3737N737SaAtaGt22B.1.4290.000047
ORF1ab/nsp3737N737YAatTat22B.1.4990.002101
ORF1ab/nsp3737N737delAAT---22B.1.6190.001742
ORF1ab/nsp3737N737SaAtaGt22P.1.140.000096
ORF1ab/nsp3737N737TaATaCC11A0.000387
ORF1ab/nsp3737N737delAAT---11A0.000387
ORF1ab/nsp3737N737delAAT---11A.2.20.001689
ORF1ab/nsp3737N737NaaTaaC11A.23.10.000704
ORF1ab/nsp3737N737DAatGat11A.23.10.000704
ORF1ab/nsp3737N737IaAtaTt11All0
ORF1ab/nsp3737N737CAAtTGt11All0
ORF1ab/nsp3737N737del1Aat-at11All0
ORF1ab/nsp3737N737DAatGat11AY.1000.000046
ORF1ab/nsp3737N737KaaTaaG11AY.1030.000006
ORF1ab/nsp3737N737SaAtaGt11AY.1130.000142
ORF1ab/nsp3737N737DAatGat11AY.1130.000142
ORF1ab/nsp3737N737DAatGat11AY.1140.000231
ORF1ab/nsp3737N737DAatGat11AY.1190.000035
ORF1ab/nsp3737N737SaAtaGt11AY.1190.000035
ORF1ab/nsp3737N737DAatGat11AY.1200.000037
ORF1ab/nsp3737N737KaaTaaA11AY.1200.000037
ORF1ab/nsp3737N737DAatGat11AY.140.000088
ORF1ab/nsp3737N737NaaTaaC11AY.200.000039
ORF1ab/nsp3737N737DAatGat11AY.230.00007
ORF1ab/nsp3737N737TaAtaCt11AY.240.000431
ORF1ab/nsp3737N737DAatGat11AY.250.000006
ORF1ab/nsp3737N737NaaTaaC11AY.260.000028
ORF1ab/nsp3737N737TaATaCC11AY.30.00001
ORF1ab/nsp3737N737KaaTaaG11AY.30.00001
ORF1ab/nsp3737N737delAAT---11AY.30.00001
ORF1ab/nsp3737N737SaAtaGt11AY.30.00001
ORF1ab/nsp3737N737NaaTaaC11AY.3.10.000085
ORF1ab/nsp3737N737DAatGat11AY.310.018519
ORF1ab/nsp3737N737NaaTaaC11AY.390.000025
ORF1ab/nsp3737N737YAatTat11AY.40.000002
ORF1ab/nsp3737N737KaaTaaG11AY.40.000002
ORF1ab/nsp3737N737HAatCat11AY.40.000002
ORF1ab/nsp3737N737NaaTaaC11AY.4.20.000022
ORF1ab/nsp3737N737YAatTat11AY.4.20.000022
ORF1ab/nsp3737N737YAatTat11AY.4.50.000107
ORF1ab/nsp3737N737TaAtaCt11AY.420.00004
ORF1ab/nsp3737N737NaaTaaC11AY.420.00004
ORF1ab/nsp3737N737TaAtaCt11AY.430.000004
ORF1ab/nsp3737N737SaAtaGt11AY.440.000006
ORF1ab/nsp3737N737KaaTaaG11AY.440.000006
ORF1ab/nsp3737N737CAAtTGt11AY.440.000006
ORF1ab/nsp3737N737TaATaCC11AY.440.000006
ORF1ab/nsp3737N737SaAtaGt11AY.450.000122
ORF1ab/nsp3737N737DAatGat11AY.450.000122
ORF1ab/nsp3737N737DAatGat11AY.460.000104
ORF1ab/nsp3737N737NaaTaaC11AY.460.000104
ORF1ab/nsp3737N737delAAT---11AY.46.20.000635
ORF1ab/nsp3737N737TaAtaCt11AY.46.20.000635
ORF1ab/nsp3737N737DAatGat11AY.46.60.000072
ORF1ab/nsp3737N737KaaTaaG11AY.50.000021
ORF1ab/nsp3737N737DAatGat11AY.5.30.000337
ORF1ab/nsp3737N737DAatGat11AY.520.000814
ORF1ab/nsp3737N737NaaTaaC11AY.590.00053
ORF1ab/nsp3737N737YAatTat11AY.60.000041
ORF1ab/nsp3737N737NaaTaaC11AY.60.000041
ORF1ab/nsp3737N737SaAtaGt11AY.620.000436
ORF1ab/nsp3737N737delAAT---11AY.670.000464
ORF1ab/nsp3737N737SaAtaGt11AY.75.10.00018
ORF1ab/nsp3737N737NaaTaaC11AY.910.00073
ORF1ab/nsp3737N737KaaTaaG11AY.920.000287
ORF1ab/nsp3737N737DAatGat11AY.930.000273
ORF1ab/nsp3737N737delAAT---11AY.940.000443
ORF1ab/nsp3737N737delAAT---11AY.990.001049
ORF1ab/nsp3737N737DAatGat11AY.990.001049
ORF1ab/nsp3737N737SaAtaGt11AY.99.20.000092
ORF1ab/nsp3737N737delAAT---11B.10.000009
ORF1ab/nsp3737N737DAatGat11B.10.000009
ORF1ab/nsp3737N737EAaTGaA11B.1.10.000018
ORF1ab/nsp3737N737KaaTaaA11B.1.10.000018
ORF1ab/nsp3737N737RaATaGA11B.1.10.000018
ORF1ab/nsp3737N737delAAT---11B.1.1.1390.022727
ORF1ab/nsp3737N737NaaTaaC11B.1.1.1410.002012
ORF1ab/nsp3737N737delAAT---11B.1.1.1420.017544
ORF1ab/nsp3737N737YAatTat11B.1.1.1710.003676
ORF1ab/nsp3737N737DAatGat11B.1.1.250.000569
ORF1ab/nsp3737N737SaAtaGt11B.1.1.3010.001179
ORF1ab/nsp3737N737HAatCat11B.1.1.3710.010417
ORF1ab/nsp3737N737NaaTaaC11B.1.1.3950.055556
ORF1ab/nsp3737N737delAAT---11B.1.1.4090.002833
ORF1ab/nsp3737N737KaaTaaG11B.1.1.5190.00004
ORF1ab/nsp3737N737IaAtaTt11B.1.1.70.000001
ORF1ab/nsp3737N737delAAT---11B.1.1570.002985
ORF1ab/nsp3737N737NaaTaaC11B.1.1600.000031
ORF1ab/nsp3737N737delAAT---11B.1.1600.000031
ORF1ab/nsp3737N737SaAtaGt11B.1.1770.000013
ORF1ab/nsp3737N737TaAtaCt11B.1.177.100.000878
ORF1ab/nsp3737N737SaAtaGt11B.1.177.120.000152
ORF1ab/nsp3737N737SaAtaGt11B.1.177.170.000821
ORF1ab/nsp3737N737SaAtaGt11B.1.177.210.000076
ORF1ab/nsp3737N737NaaTaaC11B.1.177.430.001477
ORF1ab/nsp3737N737delAAT---11B.1.177.500.004695
ORF1ab/nsp3737N737delAAT---11B.1.177.540.000606
ORF1ab/nsp3737N737delAAT---11B.1.177.630.002703
ORF1ab/nsp3737N737delAAT---11B.1.177.870.000728
ORF1ab/nsp3737N737XAaTTaA11B.1.20.000009
ORF1ab/nsp3737N737KaaTaaG11B.1.20.000009
ORF1ab/nsp3737N737YAatTat11B.1.20.000009
ORF1ab/nsp3737N737DAatGat11B.1.20.000009
ORF1ab/nsp3737N737delAAT---11B.1.2100.002132
ORF1ab/nsp3737N737NaaTaaC11B.1.2310.032258
ORF1ab/nsp3737N737NaaTaaC11B.1.2340.000132
ORF1ab/nsp3737N737YAatTat11B.1.2400.000216
ORF1ab/nsp3737N737DAatGat11B.1.2580.000067
ORF1ab/nsp3737N737NaaTaaC11B.1.258.110.000396
ORF1ab/nsp3737N737KaaTaaG11B.1.2890.00266
ORF1ab/nsp3737N737delAAT---11B.1.3190.003049
ORF1ab/nsp3737N737del1Aat-at11B.1.3360.002439
ORF1ab/nsp3737N737DAatGat11B.1.360.000146
ORF1ab/nsp3737N737SaAtaGt11B.1.360.000146
ORF1ab/nsp3737N737delAAT---11B.1.4090.000781
ORF1ab/nsp3737N737SaATaGC11B.1.4150.014286
ORF1ab/nsp3737N737NaaTaaC11B.1.5250.000113
ORF1ab/nsp3737N737SaAtaGt11B.1.5260.000024
ORF1ab/nsp3737N737NaaTaaC11B.1.6000.005848
ORF1ab/nsp3737N737delAAT---11B.1.617.10.000129
ORF1ab/nsp3737N737NaaTaaC11B.1.617.10.000129
ORF1ab/nsp3737N737KaaTaaG11B.1.617.20.000004
ORF1ab/nsp3737N737SaAtaGt11B.1.617.20.000004
ORF1ab/nsp3737N737VAATGTC11B.1.617.20.000004
ORF1ab/nsp3737N737TaAtaCt11B.1.617.20.000004
ORF1ab/nsp3737N737delAAT---11B.1.617.20.000004
ORF1ab/nsp3737N737HAatCat11B.1.617.20.000004
ORF1ab/nsp3737N737DAatGat11B.1.6210.000089
ORF1ab/nsp3737N737NaaTaaC11B.1.6210.000089
ORF1ab/nsp3737N737NaaTaaC11B.1.621.10.000506
ORF1ab/nsp3737N737SaAtaGt11B.1.6280.000352
ORF1ab/nsp3737N737DAatGat11B.1.6370.000073
ORF1ab/nsp3737N737delAAT---11B.150.017544
ORF1ab/nsp3737N737DAatGat11D.20.000075
ORF1ab/nsp3737N737delAAT---11P.10.000016
ORF1ab/nsp3737N737TaAtaCt11P.10.000016
ORF1ab/nsp3737N737NaaTaaC11P.1.120.000484
ORF1ab/nsp3737N737DAatGat11P.1.70.000319
ORF1ab/nsp3737N737NaaTaaC11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.