CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 526

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3526T526IT1344InonsynaCaaTa2565256514295-4297
ORF1ab/nsp3526T526RT1344RnonsynaCaaGa67367314295-4297
ORF1ab/nsp3526T526TT1344TsynacAacG4223570.8459724295-4297
ORF1ab/nsp3526T526TT1344TsynacAacT422340.08056874295-4297
ORF1ab/nsp3526T526TT1344TsynacAacC422310.07345974295-4297
ORF1ab/nsp3526T526AT1344AnonsynAcaGca16516514295-4297
ORF1ab/nsp3526T526delT1344deldelACA---454514295-4297
ORF1ab/nsp3526T526KT1344KnonsynaCaaAa181814295-4297
ORF1ab/nsp3526T526LT1344LnonsynACaCTa8814295-4297
ORF1ab/nsp3526T526ST1344SnonsynAcaTca530.64295-4297
ORF1ab/nsp3526T526ST1344SnonsynAcATcT510.24295-4297
ORF1ab/nsp3526T526ST1344SnonsynaCAaGT510.24295-4297
ORF1ab/nsp3526T526PT1344PnonsynAcaCca3314295-4297
ORF1ab/nsp3526T526del1T1344del1delaCaa-a210.54295-4297
ORF1ab/nsp3526T526del1T1344del1delAcA-cT210.54295-4297
ORF1ab/nsp3526T526GT1344GnonsynACaGGa1114295-4297
ORF1ab/nsp3526T526XT1344XnonsynACaTGa1114295-4297
ORF1ab/nsp3526T526CT1344CnonsynACATGT1114295-4297
ORF1ab/nsp3526T526NT1344NnonsynaCAaAC1114295-4297

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3526T526IaCaaTa25652565All0.000491
ORF1ab/nsp3526T526IaCaaTa11911191B.1.1.70.001066
ORF1ab/nsp3526T526RaCaaGa673673All0.000129
ORF1ab/nsp3526T526RaCaaGa659659A.2.50.328842
ORF1ab/nsp3526T526IaCaaTa443443B.1.617.20.001668
ORF1ab/nsp3526T526TacAacG357422All0.000068
ORF1ab/nsp3526T526TacAacT34422All0.000007
ORF1ab/nsp3526T526TacAacC31422All0.000006
ORF1ab/nsp3526T526IaCaaTa334334AY.4.20.007244
ORF1ab/nsp3526T526AAcaGca165165All0.000032
ORF1ab/nsp3526T526TacAacG100100AY.4.50.010749
ORF1ab/nsp3526T526IaCaaTa7979AY.980.006241
ORF1ab/nsp3526T526IaCaaTa7878AY.30.000776
ORF1ab/nsp3526T526IaCaaTa5656AY.1130.007974
ORF1ab/nsp3526T526TacAacG5454AY.1060.018084
ORF1ab/nsp3526T526IaCaaTa5454AY.40.000084
ORF1ab/nsp3526T526AAcaGca5353AY.440.000323
ORF1ab/nsp3526T526delACA---4545All0.000009
ORF1ab/nsp3526T526TacAacG2042B.1.1.70.000018
ORF1ab/nsp3526T526TacAacC1542B.1.1.70.000013
ORF1ab/nsp3526T526TacAacT742B.1.1.70.000006
ORF1ab/nsp3526T526TacAacG3636B.1.1.4081
ORF1ab/nsp3526T526TacAacG1830AY.40.000028
ORF1ab/nsp3526T526TacAacT830AY.40.000012
ORF1ab/nsp3526T526TacAacC430AY.40.000006
ORF1ab/nsp3526T526AAcaGca2929B.1.617.20.000109
ORF1ab/nsp3526T526IaCaaTa2828B.1.10.000508
ORF1ab/nsp3526T526TacAacG2727B.1.10.00049
ORF1ab/nsp3526T526AAcaGca2727B.1.1.70.000024
ORF1ab/nsp3526T526IaCaaTa2626AY.98.10.001259
ORF1ab/nsp3526T526IaCaaTa2020AY.430.000089
ORF1ab/nsp3526T526IaCaaTa2020B.1.20.000176
ORF1ab/nsp3526T526KaCaaAa1818All0.000003
ORF1ab/nsp3526T526delACA---1717B.1.1.70.000015
ORF1ab/nsp3526T526IaCaaTa1515B.1.1770.000198
ORF1ab/nsp3526T526TacAacG1515B.1.4270.000757
ORF1ab/nsp3526T526IaCaaTa1313B.1.1.2220.002652
ORF1ab/nsp3526T526IaCaaTa1212AY.250.000072
ORF1ab/nsp3526T526IaCaaTa1212B.10.00011
ORF1ab/nsp3526T526TacAacG1111AY.39.10.000436
ORF1ab/nsp3526T526IaCaaTa1111AY.440.000067
ORF1ab/nsp3526T526IaCaaTa1111AY.46.60.000794
ORF1ab/nsp3526T526AAcaGca1010AY.1020.000265
ORF1ab/nsp3526T526IaCaaTa1010AY.1030.000062
ORF1ab/nsp3526T526TacAacG1010P.10.000158
ORF1ab/nsp3526T526IaCaaTa99AY.1170.000761
ORF1ab/nsp3526T526IaCaaTa99D.20.000675
ORF1ab/nsp3526T526LACaCTa88All0.000002
ORF1ab/nsp3526T526TacAacG48AY.1030.000025
ORF1ab/nsp3526T526TacAacT48AY.1030.000025
ORF1ab/nsp3526T526IaCaaTa88B.1.3110.002197
ORF1ab/nsp3526T526TacAacG78B.1.617.20.000026
ORF1ab/nsp3526T526TacAacC18B.1.617.20.000004
ORF1ab/nsp3526T526IaCaaTa77AY.1020.000186
ORF1ab/nsp3526T526delACA---77AY.40.000011
ORF1ab/nsp3526T526TacAacG77AY.430.000031
ORF1ab/nsp3526T526IaCaaTa77AY.450.000852
ORF1ab/nsp3526T526IaCaaTa77Q.80.001154
ORF1ab/nsp3526T526TacAacG66B.1.3510.000178
ORF1ab/nsp3526T526SAcaTca35All0.000001
ORF1ab/nsp3526T526SAcATcT15All0
ORF1ab/nsp3526T526SaCAaGT15All0
ORF1ab/nsp3526T526IaCaaTa55AY.1000.00023
ORF1ab/nsp3526T526KaCaaAa55B.1.4290.000118
ORF1ab/nsp3526T526IaCaaTa55B.1.5260.000118
ORF1ab/nsp3526T526TacAacT55B.1.6370.000365
ORF1ab/nsp3526T526LACaCTa440.222222
ORF1ab/nsp3526T526IaCaaTa44AY.1050.002572
ORF1ab/nsp3526T526IaCaaTa44AY.200.000155
ORF1ab/nsp3526T526AAcaGca44AY.40.000006
ORF1ab/nsp3526T526IaCaaTa44AY.470.000124
ORF1ab/nsp3526T526IaCaaTa44AY.610.000419
ORF1ab/nsp3526T526TacAacG34AY.840.001312
ORF1ab/nsp3526T526TacAacT14AY.840.000437
ORF1ab/nsp3526T526TacAacC24B.1.1.2140.000111
ORF1ab/nsp3526T526TacAacT24B.1.1.2140.000111
ORF1ab/nsp3526T526KaCaaAa44B.1.5260.000094
ORF1ab/nsp3526T526IaCaaTa44B.1.6210.000354
ORF1ab/nsp3526T526PAcaCca33All0.000001
ORF1ab/nsp3526T526TacAacG23AY.250.000012
ORF1ab/nsp3526T526TacAacC13AY.250.000006
ORF1ab/nsp3526T526TacAacG13AY.30.00001
ORF1ab/nsp3526T526TacAacC13AY.30.00001
ORF1ab/nsp3526T526TacAacT13AY.30.00001
ORF1ab/nsp3526T526IaCaaTa33AY.390.000074
ORF1ab/nsp3526T526delACA---33AY.4.50.000322
ORF1ab/nsp3526T526AAcaGca33AY.430.000013
ORF1ab/nsp3526T526SAcaTca13AY.840.000437
ORF1ab/nsp3526T526SaCAaGT13AY.840.000437
ORF1ab/nsp3526T526SAcATcT13AY.840.000437
ORF1ab/nsp3526T526TacAacG33B.10.000027
ORF1ab/nsp3526T526AAcaGca33B.1.20.000026
ORF1ab/nsp3526T526TacAacC23B.1.20.000018
ORF1ab/nsp3526T526TacAacT13B.1.20.000009
ORF1ab/nsp3526T526TacAacC33B.1.258.170.000312
ORF1ab/nsp3526T526IaCaaTa33P.1.160.001122
ORF1ab/nsp3526T526TacAacG33P.30.004785
ORF1ab/nsp3526T526PAcaCca220.111111
ORF1ab/nsp3526T526RaCaaGa22A0.000774
ORF1ab/nsp3526T526IaCaaTa22A.2.5.20.003145
ORF1ab/nsp3526T526del1aCaa-a12All0
ORF1ab/nsp3526T526del1AcA-cT12All0
ORF1ab/nsp3526T526IaCaaTa22AY.1060.00067
ORF1ab/nsp3526T526IaCaaTa22AY.1180.000125
ORF1ab/nsp3526T526IaCaaTa22AY.230.000139
ORF1ab/nsp3526T526AAcaGca22AY.250.000012
ORF1ab/nsp3526T526IaCaaTa22AY.39.10.000079
ORF1ab/nsp3526T526KaCaaAa22AY.40.000003
ORF1ab/nsp3526T526LACaCTa22AY.430.000009
ORF1ab/nsp3526T526AAcaGca22AY.530.000575
ORF1ab/nsp3526T526IaCaaTa22AY.960.004149
ORF1ab/nsp3526T526IaCaaTa22AY.99.20.000184
ORF1ab/nsp3526T526KaCaaAa22B0.000256
ORF1ab/nsp3526T526delACA---22B.10.000018
ORF1ab/nsp3526T526IaCaaTa22B.1.1.1610.007067
ORF1ab/nsp3526T526TacAacG22B.1.1.3980.006452
ORF1ab/nsp3526T526TacAacG12B.1.1600.000031
ORF1ab/nsp3526T526TacAacC12B.1.1600.000031
ORF1ab/nsp3526T526delACA---22B.1.1770.000026
ORF1ab/nsp3526T526IaCaaTa22B.1.177.210.000153
ORF1ab/nsp3526T526IaCaaTa22B.1.177.730.001133
ORF1ab/nsp3526T526AAcaGca22B.1.360.000292
ORF1ab/nsp3526T526IaCaaTa22B.1.36.80.002
ORF1ab/nsp3526T526IaCaaTa22B.1.4270.000101
ORF1ab/nsp3526T526TacAacG22B.1.4290.000047
ORF1ab/nsp3526T526IaCaaTa22B.1.5090.001732
ORF1ab/nsp3526T526TacAacG22B.1.5250.000226
ORF1ab/nsp3526T526AAcaGca22B.1.5260.000047
ORF1ab/nsp3526T526IaCaaTa22B.1.5960.000174
ORF1ab/nsp3526T526RaCaaGa22B.1.6160.04878
ORF1ab/nsp3526T526delACA---22B.1.617.20.000008
ORF1ab/nsp3526T526IaCaaTa22P.10.000032
ORF1ab/nsp3526T526AAcaGca22P.1.120.000968
ORF1ab/nsp3526T526GACaGGa11A.2.50.000499
ORF1ab/nsp3526T526IaCaaTa11AD.20.000219
ORF1ab/nsp3526T526GACaGGa11All0
ORF1ab/nsp3526T526XACaTGa11All0
ORF1ab/nsp3526T526CACATGT11All0
ORF1ab/nsp3526T526NaCAaAC11All0
ORF1ab/nsp3526T526RaCaaGa11AY.1030.000006
ORF1ab/nsp3526T526AAcaGca11AY.1030.000006
ORF1ab/nsp3526T526IaCaaTa11AY.1070.000466
ORF1ab/nsp3526T526KaCaaAa11AY.1080.001103
ORF1ab/nsp3526T526TacAacG11AY.1110.000183
ORF1ab/nsp3526T526TacAacG11AY.1140.000231
ORF1ab/nsp3526T526TacAacG11AY.1180.000063
ORF1ab/nsp3526T526TacAacG11AY.1200.000037
ORF1ab/nsp3526T526IaCaaTa11AY.1200.000037
ORF1ab/nsp3526T526TacAacG11AY.200.000039
ORF1ab/nsp3526T526KaCaaAa11AY.260.000028
ORF1ab/nsp3526T526TacAacG11AY.260.000028
ORF1ab/nsp3526T526TacAacG11AY.290.000016
ORF1ab/nsp3526T526AAcaGca11AY.30.00001
ORF1ab/nsp3526T526IaCaaTa11AY.3.10.000085
ORF1ab/nsp3526T526TacAacT11AY.3.10.000085
ORF1ab/nsp3526T526AAcaGca11AY.300.000396
ORF1ab/nsp3526T526IaCaaTa11AY.330.000067
ORF1ab/nsp3526T526TacAacG11AY.360.000148
ORF1ab/nsp3526T526AAcaGca11AY.390.000025
ORF1ab/nsp3526T526RaCaaGa11AY.40.000002
ORF1ab/nsp3526T526TacAacG11AY.4.20.000022
ORF1ab/nsp3526T526AAcaGca11AY.4.20.000022
ORF1ab/nsp3526T526IaCaaTa11AY.4.50.000107
ORF1ab/nsp3526T526SAcaTca11AY.420.00004
ORF1ab/nsp3526T526IaCaaTa11AY.420.00004
ORF1ab/nsp3526T526TacAacG11AY.420.00004
ORF1ab/nsp3526T526PAcaCca11AY.430.000004
ORF1ab/nsp3526T526RaCaaGa11AY.440.000006
ORF1ab/nsp3526T526KaCaaAa11AY.440.000006
ORF1ab/nsp3526T526TacAacG11AY.440.000006
ORF1ab/nsp3526T526AAcaGca11AY.450.000122
ORF1ab/nsp3526T526AAcaGca11AY.460.000104
ORF1ab/nsp3526T526delACA---11AY.46.20.000635
ORF1ab/nsp3526T526IaCaaTa11AY.50.000021
ORF1ab/nsp3526T526AAcaGca11AY.5.40.000277
ORF1ab/nsp3526T526IaCaaTa11AY.540.000095
ORF1ab/nsp3526T526IaCaaTa11AY.590.00053
ORF1ab/nsp3526T526TacAacG11AY.60.000041
ORF1ab/nsp3526T526AAcaGca11AY.60.000041
ORF1ab/nsp3526T526TacAacT11AY.610.000105
ORF1ab/nsp3526T526IaCaaTa11AY.620.000436
ORF1ab/nsp3526T526IaCaaTa11AY.650.000533
ORF1ab/nsp3526T526AAcaGca11AY.650.000533
ORF1ab/nsp3526T526IaCaaTa11AY.7.10.000113
ORF1ab/nsp3526T526IaCaaTa11AY.720.001361
ORF1ab/nsp3526T526AAcaGca11AY.750.000056
ORF1ab/nsp3526T526LACaCTa11AY.75.10.00018
ORF1ab/nsp3526T526CACATGT11AY.840.000437
ORF1ab/nsp3526T526XACaTGa11AY.840.000437
ORF1ab/nsp3526T526RaCaaGa11AY.840.000437
ORF1ab/nsp3526T526AAcaGca11AY.850.000427
ORF1ab/nsp3526T526TacAacG11AY.9.20.000037
ORF1ab/nsp3526T526delACA---11AY.990.001049
ORF1ab/nsp3526T526TacAacG11AY.990.001049
ORF1ab/nsp3526T526AAcaGca11B.10.000009
ORF1ab/nsp3526T526delACA---11B.1.10.000018
ORF1ab/nsp3526T526RaCaaGa11B.1.10.000018
ORF1ab/nsp3526T526LACaCTa11B.1.10.000018
ORF1ab/nsp3526T526AAcaGca11B.1.1.10.000327
ORF1ab/nsp3526T526TacAacG11B.1.1.100.001115
ORF1ab/nsp3526T526TacAacG11B.1.1.1280.007092
ORF1ab/nsp3526T526TacAacT11B.1.1.1480.008772
ORF1ab/nsp3526T526TacAacG11B.1.1.1710.003676
ORF1ab/nsp3526T526IaCaaTa11B.1.1.1860.003436
ORF1ab/nsp3526T526IaCaaTa11B.1.1.2400.004695
ORF1ab/nsp3526T526AAcaGca11B.1.1.2730.006757
ORF1ab/nsp3526T526IaCaaTa11B.1.1.280.000311
ORF1ab/nsp3526T526TacAacG11B.1.1.2940.001266
ORF1ab/nsp3526T526IaCaaTa11B.1.1.3170.000412
ORF1ab/nsp3526T526AAcaGca11B.1.1.3180.000302
ORF1ab/nsp3526T526IaCaaTa11B.1.1.3680.003086
ORF1ab/nsp3526T526IaCaaTa11B.1.1.3690.000446
ORF1ab/nsp3526T526IaCaaTa11B.1.1.3890.006061
ORF1ab/nsp3526T526TacAacG11B.1.1.4320.001266
ORF1ab/nsp3526T526IaCaaTa11B.1.1.4340.000349
ORF1ab/nsp3526T526delACA---11B.1.1.5190.00004
ORF1ab/nsp3526T526IaCaaTa11B.1.1.5190.00004
ORF1ab/nsp3526T526TacAacG11B.1.1.5190.00004
ORF1ab/nsp3526T526AAcaGca11B.1.1.5190.00004
ORF1ab/nsp3526T526IaCaaTa11B.1.1.5260.003546
ORF1ab/nsp3526T526IaCaaTa11B.1.1.570.011494
ORF1ab/nsp3526T526RaCaaGa11B.1.1.70.000001
ORF1ab/nsp3526T526AAcaGca11B.1.1.700.000341
ORF1ab/nsp3526T526AAcaGca11B.1.1.80.003584
ORF1ab/nsp3526T526del1AcA-cT11B.1.1390.000733
ORF1ab/nsp3526T526delACA---11B.1.1600.000031
ORF1ab/nsp3526T526TacAacT11B.1.1770.000013
ORF1ab/nsp3526T526AAcaGca11B.1.177.210.000076
ORF1ab/nsp3526T526IaCaaTa11B.1.177.330.001645
ORF1ab/nsp3526T526TacAacG11B.1.177.430.001477
ORF1ab/nsp3526T526IaCaaTa11B.1.177.540.000606
ORF1ab/nsp3526T526delACA---11B.1.177.560.000668
ORF1ab/nsp3526T526TacAacG11B.1.177.600.000218
ORF1ab/nsp3526T526delACA---11B.1.177.860.000183
ORF1ab/nsp3526T526KaCaaAa11B.1.20.000009
ORF1ab/nsp3526T526SAcaTca11B.1.2210.000071
ORF1ab/nsp3526T526IaCaaTa11B.1.2210.000071
ORF1ab/nsp3526T526RaCaaGa11B.1.2340.000132
ORF1ab/nsp3526T526TacAacC11B.1.2360.002053
ORF1ab/nsp3526T526IaCaaTa11B.1.2400.000216
ORF1ab/nsp3526T526IaCaaTa11B.1.2650.001271
ORF1ab/nsp3526T526IaCaaTa11B.1.3260.007576
ORF1ab/nsp3526T526IaCaaTa11B.1.3400.004292
ORF1ab/nsp3526T526RaCaaGa11B.1.3560.001727
ORF1ab/nsp3526T526delACA---11B.1.360.000146
ORF1ab/nsp3526T526AAcaGca11B.1.36.210.00216
ORF1ab/nsp3526T526AAcaGca11B.1.36.290.000517
ORF1ab/nsp3526T526delACA---11B.1.4150.014286
ORF1ab/nsp3526T526RaCaaGa11B.1.4290.000024
ORF1ab/nsp3526T526IaCaaTa11B.1.4290.000024
ORF1ab/nsp3526T526AAcaGca11B.1.4290.000024
ORF1ab/nsp3526T526IaCaaTa11B.1.438.10.000107
ORF1ab/nsp3526T526AAcaGca11B.1.466.20.000391
ORF1ab/nsp3526T526NaCAaAC11B.1.4700.001404
ORF1ab/nsp3526T526TacAacT11B.1.5090.000866
ORF1ab/nsp3526T526IaCaaTa11B.1.5250.000113
ORF1ab/nsp3526T526del1aCaa-a11B.1.5820.000491
ORF1ab/nsp3526T526AAcaGca11B.1.5950.000261
ORF1ab/nsp3526T526TacAacG11B.1.617.10.000129
ORF1ab/nsp3526T526KaCaaAa11B.1.617.20.000004
ORF1ab/nsp3526T526RaCaaGa11B.1.6230.000536
ORF1ab/nsp3526T526IaCaaTa11B.1.6370.000073
ORF1ab/nsp3526T526delACA---11B.570.015152
ORF1ab/nsp3526T526delACA---11B.610.005747
ORF1ab/nsp3526T526AAcaGca11C.370.000116
ORF1ab/nsp3526T526IaCaaTa11P.20.000187
ORF1ab/nsp3526T526IaCaaTa11Q.10.000126
ORF1ab/nsp3526T526IaCaaTa11Q.70.001111
ORF1ab/nsp3526T526delACA---11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.