CoV-GLUE Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 458

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORF	CodonNum	Mut	ORF1abMut	MutType	RefCodon	MutCodon	AACount	CodonCount	CodonProp	Genome Position
ORF1ab/nsp3	458	I458T	I1276T	nonsyn	aTc	aCc	2158	2156	0.999073	4091-4093
ORF1ab/nsp3	458	I458T	I1276T	nonsyn	aTC	aCA	2158	1	0.000463392	4091-4093
ORF1ab/nsp3	458	I458T	I1276T	nonsyn	aTC	aCT	2158	1	0.000463392	4091-4093
ORF1ab/nsp3	458	I458I	I1276I	syn	atC	atT	1512	1494	0.988095	4091-4093
ORF1ab/nsp3	458	I458I	I1276I	syn	atC	atA	1512	18	0.0119048	4091-4093
ORF1ab/nsp3	458	I458V	I1276V	nonsyn	Atc	Gtc	186	186	1	4091-4093
ORF1ab/nsp3	458	I458N	I1276N	nonsyn	aTc	aAc	139	139	1	4091-4093
ORF1ab/nsp3	458	I458S	I1276S	nonsyn	aTc	aGc	76	76	1	4091-4093
ORF1ab/nsp3	458	I458F	I1276F	nonsyn	Atc	Ttc	50	50	1	4091-4093
ORF1ab/nsp3	458	I458del	I1276del	del	ATC	---	25	25	1	4091-4093
ORF1ab/nsp3	458	I458L	I1276L	nonsyn	AtC	CtG	23	18	0.782609	4091-4093
ORF1ab/nsp3	458	I458L	I1276L	nonsyn	Atc	Ctc	23	5	0.217391	4091-4093
ORF1ab/nsp3	458	I458del2	I1276del2	del	ATc	--c	2	1	0.5	4091-4093
ORF1ab/nsp3	458	I458del2	I1276del2	del	aTC	a--	2	1	0.5	4091-4093
ORF1ab/nsp3	458	I458M	I1276M	nonsyn	atC	atG	1	1	1	4091-4093
ORF1ab/nsp3	458	I458del1	I1276del1	del	aTc	a-c	1	1	1	4091-4093

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORF	CodonNum	Mut	RefCodon	MutCodon	CodonCount	AACount	Lineage	LineageCodonProp
ORF1ab/nsp3	458	I458T	aTc	aCc	2156	2158	All	0.000412
ORF1ab/nsp3	458	I458T	aTC	aCT	1	2158	All	0
ORF1ab/nsp3	458	I458T	aTC	aCA	1	2158	All	0
ORF1ab/nsp3	458	I458I	atC	atT	1494	1512	All	0.000286
ORF1ab/nsp3	458	I458I	atC	atA	18	1512	All	0.000003
ORF1ab/nsp3	458	I458T	aTc	aCc	1063	1063	B.1.1.7	0.000952
ORF1ab/nsp3	458	I458T	aTc	aCc	288	288	AY.4.2	0.006246
ORF1ab/nsp3	458	I458I	atC	atT	257	257	B.1.1.7	0.00023
ORF1ab/nsp3	458	I458T	aTc	aCc	246	246	AY.4	0.000383
ORF1ab/nsp3	458	I458I	atC	atT	236	236	AY.4	0.000367
ORF1ab/nsp3	458	I458V	Atc	Gtc	186	186	All	0.000036
ORF1ab/nsp3	458	I458N	aTc	aAc	139	139	All	0.000027
ORF1ab/nsp3	458	I458N	aTc	aAc	136	136	B.1.1.7	0.000122
ORF1ab/nsp3	458	I458I	atC	atT	134	134	B.1.525	0.015164
ORF1ab/nsp3	458	I458I	atC	atT	127	127	B.1.381	0.992188
ORF1ab/nsp3	458	I458I	atC	atT	96	96	B.1.526	0.002256
ORF1ab/nsp3	458	I458T	aTc	aCc	91	91	B.1.617.2	0.000343
ORF1ab/nsp3	458	I458V	Atc	Gtc	82	82	AY.4	0.000128
ORF1ab/nsp3	458	I458I	atC	atT	79	79	AY.26	0.002237
ORF1ab/nsp3	458	I458S	aTc	aGc	76	76	All	0.000015
ORF1ab/nsp3	458	I458I	atC	atT	54	56	B.1.2	0.000475
ORF1ab/nsp3	458	I458I	atC	atA	2	56	B.1.2	0.000018
ORF1ab/nsp3	458	I458F	Atc	Ttc	50	50	All	0.00001
ORF1ab/nsp3	458	I458T	aTc	aCc	48	48	AY.43	0.000213
ORF1ab/nsp3	458	I458V	Atc	Gtc	45	45	B.1.1.7	0.00004
ORF1ab/nsp3	458	I458I	atC	atT	45	45	B.1.617.2	0.000169
ORF1ab/nsp3	458	I458F	Atc	Ttc	43	43	B.1.177.11	0.073005
ORF1ab/nsp3	458	I458T	aTc	aCc	38	38	B.1	0.000348
ORF1ab/nsp3	458	I458I	atC	atT	36	37	AY.43	0.000159
ORF1ab/nsp3	458	I458I	atC	atA	1	37	AY.43	0.000004
ORF1ab/nsp3	458	I458T	aTc	aCc	37	37	AY.7.1	0.00417
ORF1ab/nsp3	458	I458I	atC	atT	33	33	B.1.1.328	0.559322
ORF1ab/nsp3	458	I458I	atC	atT	32	32	AY.44	0.000195
ORF1ab/nsp3	458	I458T	aTc	aCc	32	32	P.1	0.000504
ORF1ab/nsp3	458	I458S	aTc	aGc	31	31	AY.9.2	0.001139
ORF1ab/nsp3	458	I458I	atC	atT	31	31	P.1	0.000488
ORF1ab/nsp3	458	I458T	aTc	aCc	28	28	B.1.1.70	0.00955
ORF1ab/nsp3	458	I458T	aTc	aCc	28	28	B.1.2	0.000247
ORF1ab/nsp3	458	I458del	ATC	---	25	25	All	0.000005
ORF1ab/nsp3	458	I458L	AtC	CtG	18	23	All	0.000003
ORF1ab/nsp3	458	I458L	Atc	Ctc	5	23	All	0.000001
ORF1ab/nsp3	458	I458I	atC	atT	22	22	AY.103	0.000137
ORF1ab/nsp3	458	I458I	atC	atT	21	21	B.1	0.000192
ORF1ab/nsp3	458	I458I	atC	atT	19	19	B.1.1	0.000345
ORF1ab/nsp3	458	I458I	atC	atT	18	18	AY.25	0.000108
ORF1ab/nsp3	458	I458T	aTc	aCc	18	18	AY.47	0.00056
ORF1ab/nsp3	458	I458T	aTc	aCc	16	16	C.37	0.001857
ORF1ab/nsp3	458	I458T	aTc	aCc	15	15	AY.29	0.000237
ORF1ab/nsp3	458	I458I	atC	atT	14	14	A.2.5.1	0.067308
ORF1ab/nsp3	458	I458T	aTc	aCc	14	14	AY.44	0.000085
ORF1ab/nsp3	458	I458T	aTc	aCc	13	13	B.1.177	0.000171
ORF1ab/nsp3	458	I458S	aTc	aGc	12	12	AY.4	0.000019
ORF1ab/nsp3	458	I458T	aTc	aCc	12	12	B.1.1.153	0.013143
ORF1ab/nsp3	458	I458I	atC	atT	12	12	B.1.177	0.000158
ORF1ab/nsp3	458	I458I	atC	atT	11	11	AY.33	0.000735
ORF1ab/nsp3	458	I458I	atC	atT	11	11	B.1.1.37	0.002122
ORF1ab/nsp3	458	I458I	atC	atT	11	11	B.1.427	0.000555
ORF1ab/nsp3	458	I458V	Atc	Gtc	11	11	B.1.617.2	0.000041
ORF1ab/nsp3	458	I458T	aTc	aCc	10	10	AY.25	0.00006
ORF1ab/nsp3	458	I458T	aTc	aCc	10	10	B.1.1	0.000181
ORF1ab/nsp3	458	I458T	aTc	aCc	10	10	B.1.177.42	0.008945
ORF1ab/nsp3	458	I458I	atC	atT	9	9	AY.102	0.000239
ORF1ab/nsp3	458	I458L	AtC	CtG	9	9	B.1.1.7	0.000008
ORF1ab/nsp3	458	I458T	aTc	aCc	8	8	AY.9	0.000541
ORF1ab/nsp3	458	I458I	atC	atT	8	8	B.1.177.86	0.001468
ORF1ab/nsp3	458	I458L	AtC	CtG	8	8	B.1.525	0.000905
ORF1ab/nsp3	458	I458T	aTc	aCc	8	8	B.1.609	0.003835
ORF1ab/nsp3	458	I458T	aTc	aCc	7	7	AY.103	0.000043
ORF1ab/nsp3	458	I458del	ATC	---	7	7	B.1.1.7	0.000006
ORF1ab/nsp3	458	I458S	aTc	aGc	7	7	B.1.2	0.000062
ORF1ab/nsp3	458	I458I	atC	atA	7	7	Q.1	0.000884
ORF1ab/nsp3	458	I458I	atC	atT	6	6	AY.14	0.000528
ORF1ab/nsp3	458	I458T	aTc	aCc	6	6	AY.35	0.001398
ORF1ab/nsp3	458	I458T	aTc	aCc	6	6	AY.39	0.000148
ORF1ab/nsp3	458	I458I	atC	atT	6	6	AY.46	0.000624
ORF1ab/nsp3	458	I458I	atC	atT	6	6	AY.9.2	0.00022
ORF1ab/nsp3	458	I458T	aTc	aCc	5	5	AY.102	0.000133
ORF1ab/nsp3	458	I458V	Atc	Gtc	5	5	AY.14	0.00044
ORF1ab/nsp3	458	I458T	aTc	aCc	5	5	AY.3	0.00005
ORF1ab/nsp3	458	I458I	atC	atT	5	5	AY.54	0.000477
ORF1ab/nsp3	458	I458I	atC	atT	5	5	B.1.177.72	0.016949
ORF1ab/nsp3	458	I458I	atC	atT	5	5	B.1.177.81	0.000947
ORF1ab/nsp3	458	I458I	atC	atT	5	5	B.1.351	0.000149
ORF1ab/nsp3	458	I458I	atC	atT	5	5	B.1.438.1	0.000536
ORF1ab/nsp3	458	I458I	atC	atT	4	4	AY.120	0.000149
ORF1ab/nsp3	458	I458I	atC	atT	4	4	AY.20	0.000155
ORF1ab/nsp3	458	I458S	aTc	aGc	4	4	B.1.1.170	0.004988
ORF1ab/nsp3	458	I458T	aTc	aCc	4	4	B.1.1.176	0.001757
ORF1ab/nsp3	458	I458T	aTc	aCc	4	4	B.1.1.41	0.025316
ORF1ab/nsp3	458	I458I	atC	atT	4	4	Q.8	0.00066
ORF1ab/nsp3	458	I458V	Atc	Gtc	3	3	AY.103	0.000019
ORF1ab/nsp3	458	I458T	aTc	aCc	3	3	AY.106	0.001005
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.119	0.000106
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.3	0.00003
ORF1ab/nsp3	458	I458V	Atc	Gtc	3	3	AY.39	0.000074
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.39	0.000074
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.4.2	0.000065
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.5	0.000062
ORF1ab/nsp3	458	I458T	aTc	aCc	3	3	AY.5	0.000062
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.6	0.000123
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.61	0.000314
ORF1ab/nsp3	458	I458I	atC	atT	3	3	AY.74	0.000347
ORF1ab/nsp3	458	I458T	aTc	aCc	3	3	AY.87	0.002498
ORF1ab/nsp3	458	I458del	ATC	---	3	3	B.1	0.000027
ORF1ab/nsp3	458	I458I	atC	atT	3	3	B.1.1.214	0.000166
ORF1ab/nsp3	458	I458T	aTc	aCc	3	3	B.1.1.432	0.003797
ORF1ab/nsp3	458	I458S	aTc	aGc	3	3	B.1.1.7	0.000003
ORF1ab/nsp3	458	I458I	atC	atT	3	3	B.1.160	0.000094
ORF1ab/nsp3	458	I458S	aTc	aGc	3	3	B.1.160	0.000094
ORF1ab/nsp3	458	I458I	atC	atA	2	3	B.1.177.60	0.000437
ORF1ab/nsp3	458	I458I	atC	atT	1	3	B.1.177.60	0.000218
ORF1ab/nsp3	458	I458I	atC	atT	3	3	B.1.192	0.027778
ORF1ab/nsp3	458	I458S	aTc	aGc	3	3	B.1.243	0.000209
ORF1ab/nsp3	458	I458I	atC	atT	3	3	B.1.243	0.000209
ORF1ab/nsp3	458	I458T	aTc	aCc	3	3	B.1.351	0.000089
ORF1ab/nsp3	458	I458T	aTc	aCc	3	3	B.1.526	0.000071
ORF1ab/nsp3	458	I458I	atC	atT	3	3	B.1.596	0.000261
ORF1ab/nsp3	458	I458I	atC	atT	3	3	B.1.625	0.007059
ORF1ab/nsp3	458	I458T	aTC	aCT	1	2		0.055556
ORF1ab/nsp3	458	I458T	aTc	aCc	1	2		0.055556
ORF1ab/nsp3	458	I458del2	ATc	--c	1	2	All	0
ORF1ab/nsp3	458	I458del2	aTC	a--	1	2	All	0
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	AY.100	0.000092
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	AY.116	0.000574
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	AY.117	0.000169
ORF1ab/nsp3	458	I458I	atC	atT	2	2	AY.12	0.000632
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	AY.120.2.1	0.000997
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	AY.23.1	0.000835
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	AY.26	0.000057
ORF1ab/nsp3	458	I458I	atC	atT	2	2	AY.29.1	0.000441
ORF1ab/nsp3	458	I458I	atC	atT	2	2	AY.34	0.000194
ORF1ab/nsp3	458	I458V	Atc	Gtc	2	2	AY.4.2	0.000043
ORF1ab/nsp3	458	I458L	Atc	Ctc	2	2	AY.4.2	0.000043
ORF1ab/nsp3	458	I458F	Atc	Ttc	2	2	AY.44	0.000012
ORF1ab/nsp3	458	I458V	Atc	Gtc	2	2	AY.44	0.000012
ORF1ab/nsp3	458	I458I	atC	atT	2	2	AY.45	0.000243
ORF1ab/nsp3	458	I458V	Atc	Gtc	2	2	AY.5	0.000041
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	AY.61	0.00021
ORF1ab/nsp3	458	I458I	atC	atT	2	2	AY.9.1	0.000167
ORF1ab/nsp3	458	I458V	Atc	Gtc	2	2	AY.9.2	0.000073
ORF1ab/nsp3	458	I458V	Atc	Gtc	2	2	B.1.1.28	0.000622
ORF1ab/nsp3	458	I458I	atC	atT	2	2	B.1.1.28	0.000622
ORF1ab/nsp3	458	I458I	atC	atT	2	2	B.1.1.382	0.071429
ORF1ab/nsp3	458	I458I	atC	atT	2	2	B.1.1.486	0.003155
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	B.1.139	0.001466
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	B.1.169	0.029851
ORF1ab/nsp3	458	I458V	Atc	Gtc	2	2	B.1.221	0.000142
ORF1ab/nsp3	458	I458V	Atc	Gtc	2	2	B.1.351	0.000059
ORF1ab/nsp3	458	I458I	atC	atT	2	2	B.1.351.2	0.000605
ORF1ab/nsp3	458	I458I	atC	atT	2	2	B.1.36	0.000292
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	B.1.367	0.001585
ORF1ab/nsp3	458	I458T	aTc	aCc	1	2	B.1.369	0.000285
ORF1ab/nsp3	458	I458I	atC	atA	1	2	B.1.369	0.000285
ORF1ab/nsp3	458	I458T	aTC	aCA	1	2	B.1.369	0.000285
ORF1ab/nsp3	458	I458I	atC	atT	1	2	B.1.369	0.000285
ORF1ab/nsp3	458	I458I	atC	atT	2	2	B.1.408	0.00738
ORF1ab/nsp3	458	I458T	aTc	aCc	2	2	B.1.617.1	0.000258
ORF1ab/nsp3	458	I458S	aTc	aGc	2	2	B.1.617.2	0.000008
ORF1ab/nsp3	458	I458S	aTc	aGc	2	2	B.1.628	0.000705
ORF1ab/nsp3	458	I458S	aTc	aGc	2	2	C.14	0.008658
ORF1ab/nsp3	458	I458I	atC	atT	2	2	C.37	0.000232
ORF1ab/nsp3	458	I458I	atC	atT	2	2	P.1.14	0.000096
ORF1ab/nsp3	458	I458I	atC	atT	2	2	P.1.7	0.000639
ORF1ab/nsp3	458	I458I	atC	atT	1	1		0.055556
ORF1ab/nsp3	458	I458I	atC	atT	1	1	A.1	0.000282
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	A.2.5	0.000499
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	A.5	0.001923
ORF1ab/nsp3	458	I458del1	aTc	a-c	1	1	All	0
ORF1ab/nsp3	458	I458M	atC	atG	1	1	All	0
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AU.3	0.00211
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.10	0.00053
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.101	0.00049
ORF1ab/nsp3	458	I458L	Atc	Ctc	1	1	AY.103	0.000006
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.108	0.001103
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.110	0.000113
ORF1ab/nsp3	458	I458S	aTc	aGc	1	1	AY.110	0.000113
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.113	0.000142
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.116	0.000287
ORF1ab/nsp3	458	I458S	aTc	aGc	1	1	AY.117	0.000085
ORF1ab/nsp3	458	I458del	ATC	---	1	1	AY.120	0.000037
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.120.1	0.000321
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.121	0.000135
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.121	0.000135
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.13	0.000161
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.13	0.000161
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.13	0.000161
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.15	0.002222
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.20	0.000039
ORF1ab/nsp3	458	I458S	aTc	aGc	1	1	AY.20	0.000039
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.23	0.00007
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.23	0.00007
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.24	0.000431
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.24	0.000431
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.26	0.000028
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.29	0.000016
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.32	0.000532
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.34	0.000097
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.37	0.000316
ORF1ab/nsp3	458	I458L	Atc	Ctc	1	1	AY.39	0.000025
ORF1ab/nsp3	458	I458del	ATC	---	1	1	AY.4	0.000002
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.4.4	0.000409
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.4.5	0.000107
ORF1ab/nsp3	458	I458S	aTc	aGc	1	1	AY.43	0.000004
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.43	0.000004
ORF1ab/nsp3	458	I458S	aTc	aGc	1	1	AY.44	0.000006
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.46	0.000104
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.46.2	0.000635
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.46.4	0.000165
ORF1ab/nsp3	458	I458del	ATC	---	1	1	AY.46.6	0.000072
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.5.4	0.000277
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.53	0.000288
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	AY.57	0.000656
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.59	0.00053
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.6	0.000041
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.62	0.000436
ORF1ab/nsp3	458	I458del	ATC	---	1	1	AY.67	0.000464
ORF1ab/nsp3	458	I458I	atC	atA	1	1	AY.67	0.000464
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.75.1	0.00018
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.86	0.00083
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.9	0.000068
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.9.1	0.000084
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.9.2	0.000037
ORF1ab/nsp3	458	I458I	atC	atT	1	1	AY.98	0.000079
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	AY.99.2	0.000092
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B	0.000128
ORF1ab/nsp3	458	I458S	aTc	aGc	1	1	B.1	0.000009
ORF1ab/nsp3	458	I458F	Atc	Ttc	1	1	B.1.1	0.000018
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.1.1	0.000327
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.180	0.010753
ORF1ab/nsp3	458	I458F	Atc	Ttc	1	1	B.1.1.194	0.00495
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.1.222	0.000204
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.1.231	0.003096
ORF1ab/nsp3	458	I458I	atC	atA	1	1	B.1.1.237	0.005405
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.27	0.00565
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.277	0.000759
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.1.284	0.000107
ORF1ab/nsp3	458	I458I	atC	atA	1	1	B.1.1.284	0.000107
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.1.285	0.006536
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.1.29	0.010309
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.306	0.000438
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.318	0.000302
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.1.333	0.001076
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.372	0.000689
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.1.377	0.001381
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.389	0.006061
ORF1ab/nsp3	458	I458N	aTc	aAc	1	1	B.1.1.448	0.002033
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.448	0.002033
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.1.1.519	0.00004
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.1.63	0.000386
ORF1ab/nsp3	458	I458F	Atc	Ttc	1	1	B.1.1.7	0.000001
ORF1ab/nsp3	458	I458del2	ATc	--c	1	1	B.1.1.7	0.000001
ORF1ab/nsp3	458	I458S	aTc	aGc	1	1	B.1.1.70	0.000341
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.128	0.000635
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.177	0.000013
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.177.12	0.000152
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.1.177.16	0.000664
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.177.4	0.000211
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.1.177.4	0.000211
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.177.44	0.000519
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.177.7	0.000165
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.177.73	0.000566
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.177.75	0.001041
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.177.77	0.000726
ORF1ab/nsp3	458	I458M	atC	atG	1	1	B.1.2	0.000009
ORF1ab/nsp3	458	I458del2	aTC	a--	1	1	B.1.2	0.000009
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.2	0.000009
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.1.221	0.000071
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.237	0.004975
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.239	0.001221
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.239	0.001221
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.240	0.000216
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.243	0.00007
ORF1ab/nsp3	458	I458F	Atc	Ttc	1	1	B.1.258.17	0.000104
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.324	0.001605
ORF1ab/nsp3	458	I458I	atC	atA	1	1	B.1.332	0.003497
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.1.36	0.000146
ORF1ab/nsp3	458	I458N	aTc	aAc	1	1	B.1.36.10	0.004785
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.36.17	0.000494
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.367	0.000792
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.371	0.001122
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.389	0.001002
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.404	0.001302
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.416	0.001269
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.422	0.000812
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.427	0.00005
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.1.429	0.000024
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.429	0.000024
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.429	0.000024
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.438.1	0.000107
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.459	0.004082
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.466.2	0.000391
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.466.2	0.000391
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.497	0.000315
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.524	0.001406
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.575	0.000303
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	B.1.577	0.000687
ORF1ab/nsp3	458	I458del1	aTc	a-c	1	1	B.1.580	0.004065
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.595	0.000261
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.612	0.002653
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.617.1	0.000129
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.1.617.2	0.000004
ORF1ab/nsp3	458	I458N	aTc	aAc	1	1	B.1.617.2	0.000004
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.621	0.000089
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.1.621.1	0.000506
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.625	0.002353
ORF1ab/nsp3	458	I458L	AtC	CtG	1	1	B.1.636	0.006711
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	B.1.637	0.000073
ORF1ab/nsp3	458	I458I	atC	atT	1	1	B.3	0.000831
ORF1ab/nsp3	458	I458del	ATC	---	1	1	B.57	0.015152
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	C.36.3	0.000567
ORF1ab/nsp3	458	I458V	Atc	Gtc	1	1	C.37	0.000116
ORF1ab/nsp3	458	I458I	atC	atT	1	1	D.2	0.000075
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	D.2	0.000075
ORF1ab/nsp3	458	I458F	Atc	Ttc	1	1	P.1	0.000016
ORF1ab/nsp3	458	I458del	ATC	---	1	1	P.1	0.000016
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	P.1.10	0.000269
ORF1ab/nsp3	458	I458I	atC	atT	1	1	P.1.10	0.000269
ORF1ab/nsp3	458	I458I	atC	atT	1	1	P.1.12	0.000484
ORF1ab/nsp3	458	I458I	atC	atA	1	1	P.1.15	0.000232
ORF1ab/nsp3	458	I458L	Atc	Ctc	1	1	P.1.15	0.000232
ORF1ab/nsp3	458	I458I	atC	atT	1	1	Q.6	0.006623
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	Q.8	0.000165
ORF1ab/nsp3	458	I458I	atC	atT	1	1	R.1	0.00009
ORF1ab/nsp3	458	I458del	ATC	---	1	1	R.1	0.00009
ORF1ab/nsp3	458	I458T	aTc	aCc	1	1	R.1	0.00009
ORF1ab/nsp3	458	I458del	ATC	---	1	1	U.3	0.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.