CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 457

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3457D457DD1275DsyngaCgaT73573514088-4090
ORF1ab/nsp3457D457ND1275NnonsynGacAac1471460.9931974088-4090
ORF1ab/nsp3457D457ND1275NnonsynGaCAaT14710.006802724088-4090
ORF1ab/nsp3457D457GD1275GnonsyngAcgGc37360.9729734088-4090
ORF1ab/nsp3457D457GD1275GnonsyngACgGT3710.0270274088-4090
ORF1ab/nsp3457D457AD1275AnonsyngAcgCc32310.968754088-4090
ORF1ab/nsp3457D457AD1275AnonsyngACgCA3210.031254088-4090
ORF1ab/nsp3457D457YD1275YnonsynGacTac282814088-4090
ORF1ab/nsp3457D457delD1275deldelGAC---242414088-4090
ORF1ab/nsp3457D457ED1275EnonsyngaCgaA15130.8666674088-4090
ORF1ab/nsp3457D457ED1275EnonsyngaCgaG1520.1333334088-4090
ORF1ab/nsp3457D457HD1275HnonsynGacCac3314088-4090
ORF1ab/nsp3457D457SD1275SnonsynGAcAGc210.54088-4090
ORF1ab/nsp3457D457SD1275SnonsynGACAGT210.54088-4090
ORF1ab/nsp3457D457VD1275VnonsyngAcgTc1114088-4090

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3457D457DgaCgaT735735All0.000141
ORF1ab/nsp3457D457NGacAac146147All0.000028
ORF1ab/nsp3457D457NGaCAaT1147All0
ORF1ab/nsp3457D457DgaCgaT104104B.1.1.70.000093
ORF1ab/nsp3457D457DgaCgaT6767B.1.617.20.000252
ORF1ab/nsp3457D457DgaCgaT5959AY.40.000092
ORF1ab/nsp3457D457DgaCgaT4040P.10.00063
ORF1ab/nsp3457D457GgAcgGc3637All0.000007
ORF1ab/nsp3457D457GgACgGT137All0
ORF1ab/nsp3457D457AgAcgCc3132All0.000006
ORF1ab/nsp3457D457AgACgCA132All0
ORF1ab/nsp3457D457DgaCgaT3232B.1.1061
ORF1ab/nsp3457D457NGacAac3131B.1.10.000562
ORF1ab/nsp3457D457DgaCgaT3030AY.50.000619
ORF1ab/nsp3457D457DgaCgaT2929B.1.10.000526
ORF1ab/nsp3457D457YGacTac2828All0.000005
ORF1ab/nsp3457D457DgaCgaT2828AY.440.00017
ORF1ab/nsp3457D457delGAC---2424All0.000005
ORF1ab/nsp3457D457DgaCgaT2424AY.430.000106
ORF1ab/nsp3457D457DgaCgaT2323AY.750.001289
ORF1ab/nsp3457D457DgaCgaT2323B.1.20.000203
ORF1ab/nsp3457D457DgaCgaT2121AY.1000.000966
ORF1ab/nsp3457D457AgAcgCc1717AY.740.001966
ORF1ab/nsp3457D457NGacAac1616AY.250.000096
ORF1ab/nsp3457D457DgaCgaT1616AY.30.000159
ORF1ab/nsp3457D457EgaCgaA1315All0.000002
ORF1ab/nsp3457D457EgaCgaG215All0
ORF1ab/nsp3457D457DgaCgaT1515B.10.000137
ORF1ab/nsp3457D457NGacAac1515B.1.20.000132
ORF1ab/nsp3457D457NGacAac1414AY.750.000784
ORF1ab/nsp3457D457DgaCgaT1212AY.250.000072
ORF1ab/nsp3457D457DgaCgaT1212B.1.2390.014652
ORF1ab/nsp3457D457DgaCgaT1111AY.1020.000292
ORF1ab/nsp3457D457DgaCgaT1111B.1.5250.001245
ORF1ab/nsp3457D457GgAcgGc1010AY.40.000016
ORF1ab/nsp3457D457NGacAac1010B.1.1.70.000009
ORF1ab/nsp3457D457DgaCgaT1010B.1.5260.000235
ORF1ab/nsp3457D457NGacAac99AY.4.20.000195
ORF1ab/nsp3457D457YGacTac99B.10.000082
ORF1ab/nsp3457D457GgAcgGc99B.1.1.70.000008
ORF1ab/nsp3457D457DgaCgaT88P.1.160.002993
ORF1ab/nsp3457D457delGAC---77B.1.1.70.000006
ORF1ab/nsp3457D457DgaCgaT66AY.1030.000037
ORF1ab/nsp3457D457DgaCgaT66B.1.1.3720.004132
ORF1ab/nsp3457D457DgaCgaT66B.1.36.290.003104
ORF1ab/nsp3457D457DgaCgaT66B.1.910.012448
ORF1ab/nsp3457D457DgaCgaT55AY.390.000124
ORF1ab/nsp3457D457DgaCgaT55AY.470.000156
ORF1ab/nsp3457D457EgaCgaA45B.1.1.70.000004
ORF1ab/nsp3457D457EgaCgaG15B.1.1.70.000001
ORF1ab/nsp3457D457DgaCgaT55B.1.1.700.001705
ORF1ab/nsp3457D457DgaCgaT55B.1.3510.000149
ORF1ab/nsp3457D457DgaCgaT55B.1.5240.007032
ORF1ab/nsp3457D457NGacAac44AY.39.10.000158
ORF1ab/nsp3457D457NGacAac44AY.440.000024
ORF1ab/nsp3457D457DgaCgaT44AY.740.000463
ORF1ab/nsp3457D457DgaCgaT44AY.98.10.000194
ORF1ab/nsp3457D457NGacAac44B.1.1.2630.006231
ORF1ab/nsp3457D457DgaCgaT44B.1.1600.000125
ORF1ab/nsp3457D457GgAcgGc44B.1.2580.000266
ORF1ab/nsp3457D457DgaCgaT330.166667
ORF1ab/nsp3457D457HGacCac33All0.000001
ORF1ab/nsp3457D457NGacAac33AY.1030.000019
ORF1ab/nsp3457D457AgAcgCc33AY.1030.000019
ORF1ab/nsp3457D457DgaCgaT33AY.1190.000106
ORF1ab/nsp3457D457DgaCgaT33AY.16.10.00141
ORF1ab/nsp3457D457DgaCgaT33AY.330.0002
ORF1ab/nsp3457D457AgAcgCc33AY.40.000005
ORF1ab/nsp3457D457delGAC---33B.10.000027
ORF1ab/nsp3457D457DgaCgaT33B.1.1.5190.000119
ORF1ab/nsp3457D457NGacAac33B.1.1600.000094
ORF1ab/nsp3457D457NGacAac33B.1.1770.00004
ORF1ab/nsp3457D457GgAcgGc33B.1.177.820.001432
ORF1ab/nsp3457D457AgAcgCc33B.1.20.000026
ORF1ab/nsp3457D457DgaCgaT33B.1.258.110.001189
ORF1ab/nsp3457D457DgaCgaT33B.1.351.30.002629
ORF1ab/nsp3457D457DgaCgaT33B.1.36.180.001261
ORF1ab/nsp3457D457DgaCgaT33B.1.4270.000151
ORF1ab/nsp3457D457NGacAac33B.1.617.20.000011
ORF1ab/nsp3457D457DgaCgaT33D.20.000225
ORF1ab/nsp3457D457YGacTac33D.20.000225
ORF1ab/nsp3457D457SGACAGT120.055556
ORF1ab/nsp3457D457NGacAac120.055556
ORF1ab/nsp3457D457GgACgGT120.055556
ORF1ab/nsp3457D457NGaCAaT120.055556
ORF1ab/nsp3457D457SGAcAGc120.055556
ORF1ab/nsp3457D457GgAcgGc120.055556
ORF1ab/nsp3457D457SGAcAGc12All0
ORF1ab/nsp3457D457SGACAGT12All0
ORF1ab/nsp3457D457DgaCgaT22AY.1200.000074
ORF1ab/nsp3457D457DgaCgaT22AY.200.000078
ORF1ab/nsp3457D457DgaCgaT22AY.29.10.000441
ORF1ab/nsp3457D457NGacAac22AY.30.00002
ORF1ab/nsp3457D457EgaCgaA22AY.390.000049
ORF1ab/nsp3457D457DgaCgaT22AY.39.10.000079
ORF1ab/nsp3457D457EgaCgaA22AY.40.000003
ORF1ab/nsp3457D457YGacTac22AY.40.000003
ORF1ab/nsp3457D457NGacAac22AY.40.000003
ORF1ab/nsp3457D457DgaCgaT22AY.4.20.000043
ORF1ab/nsp3457D457YGacTac22AY.430.000009
ORF1ab/nsp3457D457DgaCgaT22AY.640.00119
ORF1ab/nsp3457D457DgaCgaT22AY.980.000158
ORF1ab/nsp3457D457YGacTac22B0.000256
ORF1ab/nsp3457D457DgaCgaT22B.1.1.1530.002191
ORF1ab/nsp3457D457DgaCgaT22B.1.1.2070.002364
ORF1ab/nsp3457D457YGacTac22B.1.1.70.000002
ORF1ab/nsp3457D457AgAcgCc22B.1.1.70.000002
ORF1ab/nsp3457D457DgaCgaT22B.1.1770.000026
ORF1ab/nsp3457D457NGacAac22B.1.177.720.00678
ORF1ab/nsp3457D457GgAcgGc22B.1.20.000018
ORF1ab/nsp3457D457DgaCgaT22B.1.2430.000139
ORF1ab/nsp3457D457DgaCgaT22B.1.2580.000133
ORF1ab/nsp3457D457DgaCgaT22B.1.4290.000047
ORF1ab/nsp3457D457DgaCgaT22B.1.4990.002101
ORF1ab/nsp3457D457DgaCgaT22B.1.6370.000146
ORF1ab/nsp3457D457DgaCgaT22C.36.30.001134
ORF1ab/nsp3457D457NGacAac22P.10.000032
ORF1ab/nsp3457D457YGacTac11A0.000387
ORF1ab/nsp3457D457VgAcgTc11All0
ORF1ab/nsp3457D457GgAcgGc11AY.1000.000046
ORF1ab/nsp3457D457NGacAac11AY.1020.000027
ORF1ab/nsp3457D457NGacAac11AY.1080.001103
ORF1ab/nsp3457D457DgaCgaT11AY.110.001339
ORF1ab/nsp3457D457DgaCgaT11AY.1160.000287
ORF1ab/nsp3457D457NGacAac11AY.1170.000085
ORF1ab/nsp3457D457delGAC---11AY.1200.000037
ORF1ab/nsp3457D457DgaCgaT11AY.1210.000135
ORF1ab/nsp3457D457DgaCgaT11AY.140.000088
ORF1ab/nsp3457D457DgaCgaT11AY.230.00007
ORF1ab/nsp3457D457DgaCgaT11AY.290.000016
ORF1ab/nsp3457D457DgaCgaT11AY.3.10.000085
ORF1ab/nsp3457D457NGacAac11AY.300.000396
ORF1ab/nsp3457D457DgaCgaT11AY.340.000097
ORF1ab/nsp3457D457HGacCac11AY.40.000002
ORF1ab/nsp3457D457delGAC---11AY.40.000002
ORF1ab/nsp3457D457EgaCgaG11AY.4.20.000022
ORF1ab/nsp3457D457NGacAac11AY.420.00004
ORF1ab/nsp3457D457YGacTac11AY.440.000006
ORF1ab/nsp3457D457AgAcgCc11AY.440.000006
ORF1ab/nsp3457D457EgaCgaA11AY.440.000006
ORF1ab/nsp3457D457DgaCgaT11AY.450.000122
ORF1ab/nsp3457D457delGAC---11AY.46.60.000072
ORF1ab/nsp3457D457NGacAac11AY.480.000465
ORF1ab/nsp3457D457EgaCgaA11AY.50.000021
ORF1ab/nsp3457D457DgaCgaT11AY.5.40.000277
ORF1ab/nsp3457D457DgaCgaT11AY.500.000799
ORF1ab/nsp3457D457DgaCgaT11AY.530.000288
ORF1ab/nsp3457D457delGAC---11AY.670.000464
ORF1ab/nsp3457D457DgaCgaT11AY.840.000437
ORF1ab/nsp3457D457DgaCgaT11AY.850.000427
ORF1ab/nsp3457D457DgaCgaT11AY.930.000273
ORF1ab/nsp3457D457NGacAac11AY.950.000761
ORF1ab/nsp3457D457DgaCgaT11B0.000128
ORF1ab/nsp3457D457GgAcgGc11B.10.000009
ORF1ab/nsp3457D457AgACgCA11B.10.000009
ORF1ab/nsp3457D457YGacTac11B.1.10.000018
ORF1ab/nsp3457D457DgaCgaT11B.1.1.1760.000439
ORF1ab/nsp3457D457DgaCgaT11B.1.1.2160.00089
ORF1ab/nsp3457D457DgaCgaT11B.1.1.2550.00303
ORF1ab/nsp3457D457DgaCgaT11B.1.1.3170.000412
ORF1ab/nsp3457D457DgaCgaT11B.1.1.3480.000796
ORF1ab/nsp3457D457NGacAac11B.1.1.390.00051
ORF1ab/nsp3457D457DgaCgaT11B.1.1.4340.000349
ORF1ab/nsp3457D457DgaCgaT11B.1.1.4480.002033
ORF1ab/nsp3457D457delGAC---11B.1.1.5190.00004
ORF1ab/nsp3457D457HGacCac11B.1.1.70.000001
ORF1ab/nsp3457D457DgaCgaT11B.1.1390.000733
ORF1ab/nsp3457D457AgAcgCc11B.1.1600.000031
ORF1ab/nsp3457D457GgAcgGc11B.1.1770.000013
ORF1ab/nsp3457D457YGacTac11B.1.1770.000013
ORF1ab/nsp3457D457delGAC---11B.1.177.160.000664
ORF1ab/nsp3457D457delGAC---11B.1.177.40.000211
ORF1ab/nsp3457D457YGacTac11B.1.177.70.000165
ORF1ab/nsp3457D457DgaCgaT11B.1.177.750.001041
ORF1ab/nsp3457D457DgaCgaT11B.1.177.810.000189
ORF1ab/nsp3457D457NGacAac11B.1.177.830.001481
ORF1ab/nsp3457D457DgaCgaT11B.1.1950.005025
ORF1ab/nsp3457D457YGacTac11B.1.20.000009
ORF1ab/nsp3457D457EgaCgaA11B.1.2060.000816
ORF1ab/nsp3457D457DgaCgaT11B.1.214.20.0006
ORF1ab/nsp3457D457delGAC---11B.1.2210.000071
ORF1ab/nsp3457D457NGacAac11B.1.2220.001692
ORF1ab/nsp3457D457NGacAac11B.1.2340.000132
ORF1ab/nsp3457D457DgaCgaT11B.1.2400.000216
ORF1ab/nsp3457D457NGacAac11B.1.2400.000216
ORF1ab/nsp3457D457VgAcgTc11B.1.2400.000216
ORF1ab/nsp3457D457NGacAac11B.1.3490.000715
ORF1ab/nsp3457D457NGacAac11B.1.3510.00003
ORF1ab/nsp3457D457delGAC---11B.1.360.000146
ORF1ab/nsp3457D457DgaCgaT11B.1.4090.000781
ORF1ab/nsp3457D457delGAC---11B.1.4290.000024
ORF1ab/nsp3457D457DgaCgaT11B.1.4330.003195
ORF1ab/nsp3457D457DgaCgaT11B.1.4410.009615
ORF1ab/nsp3457D457NGacAac11B.1.5260.000024
ORF1ab/nsp3457D457GgAcgGc11B.1.5440.006024
ORF1ab/nsp3457D457YGacTac11B.1.5810.009434
ORF1ab/nsp3457D457EgaCgaA11B.1.5960.000087
ORF1ab/nsp3457D457NGacAac11B.1.6090.000479
ORF1ab/nsp3457D457GgAcgGc11B.1.617.20.000004
ORF1ab/nsp3457D457EgaCgaA11B.1.617.20.000004
ORF1ab/nsp3457D457YGacTac11B.1.6230.000536
ORF1ab/nsp3457D457GgAcgGc11B.1.6370.000073
ORF1ab/nsp3457D457delGAC---11B.570.015152
ORF1ab/nsp3457D457DgaCgaT11C.370.000116
ORF1ab/nsp3457D457NGacAac11C.370.000116
ORF1ab/nsp3457D457NGacAac11D.20.000075
ORF1ab/nsp3457D457HGacCac11D.20.000075
ORF1ab/nsp3457D457delGAC---11P.10.000016
ORF1ab/nsp3457D457AgAcgCc11P.10.000016
ORF1ab/nsp3457D457GgAcgGc11P.10.000016
ORF1ab/nsp3457D457DgaCgaT11P.1.140.000048
ORF1ab/nsp3457D457DgaCgaT11P.1.150.000232
ORF1ab/nsp3457D457DgaCgaT11P.20.000187
ORF1ab/nsp3457D457delGAC---11R.10.00009
ORF1ab/nsp3457D457DgaCgaT11R.10.00009
ORF1ab/nsp3457D457delGAC---11U.30.003861

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.