CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 44

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp344V44VV862VsyngtTgtC5895210.884552849-2851
ORF1ab/nsp344V44VV862VsyngtTgtA589420.07130732849-2851
ORF1ab/nsp344V44VV862VsyngtTgtG589260.04414262849-2851
ORF1ab/nsp344V44IV862InonsynGttAtt27327312849-2851
ORF1ab/nsp344V44FV862FnonsynGttTtt97960.9896912849-2851
ORF1ab/nsp344V44FV862FnonsynGtTTtC9710.01030932849-2851
ORF1ab/nsp344V44GV862GnonsyngTtgGt43250.5813952849-2851
ORF1ab/nsp344V44GV862GnonsyngTTgGC43170.3953492849-2851
ORF1ab/nsp344V44GV862GnonsyngTTgGA4310.02325582849-2851
ORF1ab/nsp344V44delV862deldelGTT---383812849-2851
ORF1ab/nsp344V44LV862LnonsynGttCtt33280.8484852849-2851
ORF1ab/nsp344V44LV862LnonsynGtTCtG3320.06060612849-2851
ORF1ab/nsp344V44LV862LnonsynGtTCtC3320.06060612849-2851
ORF1ab/nsp344V44LV862LnonsynGtTTtG3310.0303032849-2851
ORF1ab/nsp344V44DV862DnonsyngTtgAt222212849-2851
ORF1ab/nsp344V44AV862AnonsyngTtgCt141412849-2851
ORF1ab/nsp344V44del1V862del1delGtt-tt6612849-2851
ORF1ab/nsp344V44SV862SnonsynGTtAGt540.82849-2851
ORF1ab/nsp344V44SV862SnonsynGTTTCG510.22849-2851
ORF1ab/nsp344V44NV862NnonsynGTtAAt3312849-2851
ORF1ab/nsp344V44EV862EnonsyngTTgAG1112849-2851
ORF1ab/nsp344V44HV862HnonsynGTtCAt1112849-2851
ORF1ab/nsp344V44QV862QnonsynGTTCAG1112849-2851

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp344V44VgtTgtC521589All0.0001
ORF1ab/nsp344V44VgtTgtA42589All0.000008
ORF1ab/nsp344V44VgtTgtG26589All0.000005
ORF1ab/nsp344V44IGttAtt273273All0.000052
ORF1ab/nsp344V44VgtTgtC179179AY.4.20.003882
ORF1ab/nsp344V44VgtTgtC8998B.1.1.70.00008
ORF1ab/nsp344V44VgtTgtA698B.1.1.70.000005
ORF1ab/nsp344V44VgtTgtG398B.1.1.70.000003
ORF1ab/nsp344V44FGttTtt9697All0.000018
ORF1ab/nsp344V44FGtTTtC197All0
ORF1ab/nsp344V44IGttAtt8686B.1.1.5190.003415
ORF1ab/nsp344V44VgtTgtC5281AY.40.000081
ORF1ab/nsp344V44VgtTgtG1781AY.40.000026
ORF1ab/nsp344V44VgtTgtA1281AY.40.000019
ORF1ab/nsp344V44VgtTgtC4747B.1.6210.00416
ORF1ab/nsp344V44GgTtgGt2543All0.000005
ORF1ab/nsp344V44GgTTgGC1743All0.000003
ORF1ab/nsp344V44GgTTgGA143All0
ORF1ab/nsp344V44delGTT---3838All0.000007
ORF1ab/nsp344V44IGttAtt3636B.1.1.3550.553846
ORF1ab/nsp344V44LGttCtt2833All0.000005
ORF1ab/nsp344V44LGtTCtC233All0
ORF1ab/nsp344V44LGtTCtG233All0
ORF1ab/nsp344V44LGtTTtG133All0
ORF1ab/nsp344V44IGttAtt2828B.1.1770.000369
ORF1ab/nsp344V44VgtTgtC2323AY.1030.000143
ORF1ab/nsp344V44DgTtgAt2222All0.000004
ORF1ab/nsp344V44FGttTtt2121AY.1030.00013
ORF1ab/nsp344V44VgtTgtC2020AY.250.00012
ORF1ab/nsp344V44VgtTgtC1419B.1.617.20.000053
ORF1ab/nsp344V44VgtTgtA319B.1.617.20.000011
ORF1ab/nsp344V44VgtTgtG219B.1.617.20.000008
ORF1ab/nsp344V44VgtTgtC1616B.10.000147
ORF1ab/nsp344V44AgTtgCt1414All0.000003
ORF1ab/nsp344V44VgtTgtC1414AY.1140.003235
ORF1ab/nsp344V44IGttAtt1414B.10.000128
ORF1ab/nsp344V44LGttCtt1414B.1.1650.166667
ORF1ab/nsp344V44IGttAtt1212B.1.5270.044444
ORF1ab/nsp344V44IGttAtt1212B.1.5311
ORF1ab/nsp344V44IGttAtt1212B.1.617.20.000045
ORF1ab/nsp344V44GgTTgGC611A0.002322
ORF1ab/nsp344V44GgTtgGt511A0.001935
ORF1ab/nsp344V44IGttAtt1111AY.3.10.000938
ORF1ab/nsp344V44FGttTtt1111AY.40.000017
ORF1ab/nsp344V44FGttTtt1010B.1.1.70.000009
ORF1ab/nsp344V44VgtTgtA1010B.1.5960.000871
ORF1ab/nsp344V44LGttCtt99B.1.1.2140.000499
ORF1ab/nsp344V44IGttAtt88AY.40.000012
ORF1ab/nsp344V44GgTtgGt48B0.000511
ORF1ab/nsp344V44GgTTgGC48B0.000511
ORF1ab/nsp344V44DgTtgAt88B.1.1.70.000007
ORF1ab/nsp344V44IGttAtt77AY.1020.000186
ORF1ab/nsp344V44VgtTgtC77AY.1160.002007
ORF1ab/nsp344V44DgTtgAt77B.1.5250.000792
ORF1ab/nsp344V44del1Gtt-tt66All0.000001
ORF1ab/nsp344V44FGttTtt66AY.60.000247
ORF1ab/nsp344V44del1Gtt-tt66B.10.000055
ORF1ab/nsp344V44FGttTtt66B.10.000055
ORF1ab/nsp344V44FGttTtt66B.400.002186
ORF1ab/nsp344V44VgtTgtC55A0.001935
ORF1ab/nsp344V44SGTtAGt45All0.000001
ORF1ab/nsp344V44SGTTTCG15All0
ORF1ab/nsp344V44FGttTtt55AY.250.00003
ORF1ab/nsp344V44VgtTgtC55AY.370.00158
ORF1ab/nsp344V44VgtTgtC55AY.470.000156
ORF1ab/nsp344V44delGTT---55B.10.000046
ORF1ab/nsp344V44delGTT---55B.1.1.70.000004
ORF1ab/nsp344V44delGTT---440.222222
ORF1ab/nsp344V44IGttAtt440.222222
ORF1ab/nsp344V44GgTtgGt440.222222
ORF1ab/nsp344V44SGTtAGt440.222222
ORF1ab/nsp344V44LGtTCtC240.111111
ORF1ab/nsp344V44LGttCtt240.111111
ORF1ab/nsp344V44VgtTgtC44AY.140.000352
ORF1ab/nsp344V44VgtTgtC44AY.30.00004
ORF1ab/nsp344V44FGttTtt44AY.430.000018
ORF1ab/nsp344V44IGttAtt44AY.440.000024
ORF1ab/nsp344V44VgtTgtC44B0.000511
ORF1ab/nsp344V44GgTtgGt34B.10.000027
ORF1ab/nsp344V44GgTTgGC14B.10.000009
ORF1ab/nsp344V44VgtTgtC44B.1.1.4480.00813
ORF1ab/nsp344V44AgTtgCt44B.1.1.70.000004
ORF1ab/nsp344V44VgtTgtC34B.1.20.000026
ORF1ab/nsp344V44VgtTgtA14B.1.20.000009
ORF1ab/nsp344V44FGttTtt44B.1.617.20.000015
ORF1ab/nsp344V44NGTtAAt33All0.000001
ORF1ab/nsp344V44IGttAtt33AY.30.00003
ORF1ab/nsp344V44delGTT---33B.1.1.330.001263
ORF1ab/nsp344V44delGTT---33B.1.1.3480.002389
ORF1ab/nsp344V44IGttAtt33B.1.1.70.000003
ORF1ab/nsp344V44FGttTtt33B.1.177.580.003995
ORF1ab/nsp344V44IGttAtt33B.1.6210.000266
ORF1ab/nsp344V44FGttTtt33P.10.000047
ORF1ab/nsp344V44VgtTgtC220.111111
ORF1ab/nsp344V44GgTTgGC12A.2.40.003367
ORF1ab/nsp344V44GgTtgGt12A.2.40.003367
ORF1ab/nsp344V44GgTTgGC22A.2.50.000998
ORF1ab/nsp344V44GgTTgGC12A.50.001923
ORF1ab/nsp344V44GgTtgGt12A.50.001923
ORF1ab/nsp344V44IGttAtt22AY.1180.000125
ORF1ab/nsp344V44VgtTgtC22AY.1200.000074
ORF1ab/nsp344V44VgtTgtA12AY.200.000039
ORF1ab/nsp344V44VgtTgtC12AY.200.000039
ORF1ab/nsp344V44FGttTtt22AY.290.000032
ORF1ab/nsp344V44IGttAtt22AY.330.000134
ORF1ab/nsp344V44IGttAtt22AY.4.20.000043
ORF1ab/nsp344V44IGttAtt22AY.430.000009
ORF1ab/nsp344V44IGttAtt22AY.450.000243
ORF1ab/nsp344V44GgTtgGt22B.1.10.000036
ORF1ab/nsp344V44FGttTtt22B.1.1.4290.009217
ORF1ab/nsp344V44IGttAtt22B.1.20.000018
ORF1ab/nsp344V44GgTTgGA12B.1.20.000009
ORF1ab/nsp344V44GgTtgGt12B.1.20.000009
ORF1ab/nsp344V44DgTtgAt22B.1.2210.000142
ORF1ab/nsp344V44NGTtAAt22B.1.2210.000142
ORF1ab/nsp344V44IGttAtt22B.1.2210.000142
ORF1ab/nsp344V44IGttAtt22B.1.3510.000059
ORF1ab/nsp344V44VgtTgtC22B.1.4160.002538
ORF1ab/nsp344V44delGTT---22B.1.4240.016129
ORF1ab/nsp344V44delGTT---22B.1.4290.000047
ORF1ab/nsp344V44LGtTCtG12B.1.4290.000024
ORF1ab/nsp344V44VgtTgtC12B.1.4290.000024
ORF1ab/nsp344V44LGttCtt12B.1.4290.000024
ORF1ab/nsp344V44VgtTgtG12B.1.4290.000024
ORF1ab/nsp344V44AgTtgCt22B.1.5250.000226
ORF1ab/nsp344V44FGttTtt22C.370.000232
ORF1ab/nsp344V44delGTT---22N.60.014184
ORF1ab/nsp344V44delGTT---22P.10.000032
ORF1ab/nsp344V44VgtTgtC12P.10.000016
ORF1ab/nsp344V44VgtTgtA12P.10.000016
ORF1ab/nsp344V44NGTtAAt110.055556
ORF1ab/nsp344V44DgTtgAt110.055556
ORF1ab/nsp344V44VgtTgtC11A.20.000662
ORF1ab/nsp344V44GgTTgGC11A.20.000662
ORF1ab/nsp344V44VgtTgtC11A.2.40.003367
ORF1ab/nsp344V44DgTtgAt11A.2.40.003367
ORF1ab/nsp344V44VgtTgtC11A.50.001923
ORF1ab/nsp344V44HGTtCAt11All0
ORF1ab/nsp344V44EgTTgAG11All0
ORF1ab/nsp344V44QGTTCAG11All0
ORF1ab/nsp344V44IGttAtt11AY.1160.000287
ORF1ab/nsp344V44VgtTgtG11AY.116.10.000311
ORF1ab/nsp344V44IGttAtt11AY.1190.000035
ORF1ab/nsp344V44GgTtgGt11AY.160.00038
ORF1ab/nsp344V44VgtTgtC11AY.16.10.00047
ORF1ab/nsp344V44VgtTgtC11AY.290.000016
ORF1ab/nsp344V44delGTT---11AY.30.00001
ORF1ab/nsp344V44IGttAtt11AY.340.000097
ORF1ab/nsp344V44FGttTtt11AY.390.000025
ORF1ab/nsp344V44VgtTgtC11AY.390.000025
ORF1ab/nsp344V44IGttAtt11AY.390.000025
ORF1ab/nsp344V44AgTtgCt11AY.40.000002
ORF1ab/nsp344V44FGttTtt11AY.4.20.000022
ORF1ab/nsp344V44FGttTtt11AY.410.000294
ORF1ab/nsp344V44LGtTCtG11AY.430.000004
ORF1ab/nsp344V44VgtTgtA11AY.430.000004
ORF1ab/nsp344V44AgTtgCt11AY.440.000006
ORF1ab/nsp344V44delGTT---11AY.440.000006
ORF1ab/nsp344V44VgtTgtA11AY.450.000122
ORF1ab/nsp344V44VgtTgtC11AY.460.000104
ORF1ab/nsp344V44FGttTtt11AY.50.000021
ORF1ab/nsp344V44IGttAtt11AY.540.000095
ORF1ab/nsp344V44delGTT---11AY.60.000041
ORF1ab/nsp344V44SGTTTCG11AY.670.000464
ORF1ab/nsp344V44VgtTgtA11AY.750.000056
ORF1ab/nsp344V44VgtTgtG11AY.860.00083
ORF1ab/nsp344V44AgTtgCt11AY.90.000068
ORF1ab/nsp344V44delGTT---11AY.9.20.000037
ORF1ab/nsp344V44FGttTtt11AY.930.000273
ORF1ab/nsp344V44GgTtgGt11AY.980.000079
ORF1ab/nsp344V44FGttTtt11B0.000128
ORF1ab/nsp344V44LGttCtt11B.10.000009
ORF1ab/nsp344V44DgTtgAt11B.10.000009
ORF1ab/nsp344V44AgTtgCt11B.10.000009
ORF1ab/nsp344V44delGTT---11B.1.10.000018
ORF1ab/nsp344V44LGttCtt11B.1.10.000018
ORF1ab/nsp344V44FGttTtt11B.1.10.000018
ORF1ab/nsp344V44IGttAtt11B.1.1.1610.003534
ORF1ab/nsp344V44VgtTgtC11B.1.1.1710.003676
ORF1ab/nsp344V44VgtTgtC11B.1.1.2220.000204
ORF1ab/nsp344V44AgTtgCt11B.1.1.250.000569
ORF1ab/nsp344V44VgtTgtA11B.1.1.3160.000925
ORF1ab/nsp344V44IGttAtt11B.1.1.4090.002833
ORF1ab/nsp344V44delGTT---11B.1.1.4160.000905
ORF1ab/nsp344V44VgtTgtA11B.1.1.4290.004608
ORF1ab/nsp344V44FGtTTtC11B.1.1.500.000679
ORF1ab/nsp344V44VgtTgtA11B.1.1.500.000679
ORF1ab/nsp344V44VgtTgtC11B.1.1.5250.005464
ORF1ab/nsp344V44IGttAtt11B.1.1.700.000341
ORF1ab/nsp344V44delGTT---11B.1.1.700.000341
ORF1ab/nsp344V44VgtTgtC11B.1.1270.002198
ORF1ab/nsp344V44GgTtgGt11B.1.1600.000031
ORF1ab/nsp344V44VgtTgtA11B.1.1600.000031
ORF1ab/nsp344V44IGttAtt11B.1.1600.000031
ORF1ab/nsp344V44VgtTgtC11B.1.1770.000013
ORF1ab/nsp344V44IGttAtt11B.1.177.320.00135
ORF1ab/nsp344V44VgtTgtA11B.1.177.480.003125
ORF1ab/nsp344V44delGTT---11B.1.177.510.004566
ORF1ab/nsp344V44VgtTgtG11B.1.177.870.000728
ORF1ab/nsp344V44FGttTtt11B.1.221.40.004167
ORF1ab/nsp344V44FGttTtt11B.1.2340.000132
ORF1ab/nsp344V44DgTtgAt11B.1.3110.000275
ORF1ab/nsp344V44AgTtgCt11B.1.3380.008621
ORF1ab/nsp344V44FGttTtt11B.1.351.50.0006
ORF1ab/nsp344V44FGttTtt11B.1.360.000146
ORF1ab/nsp344V44VgtTgtC11B.1.36.100.004785
ORF1ab/nsp344V44IGttAtt11B.1.36.210.00216
ORF1ab/nsp344V44GgTTgGC11B.1.3750.00082
ORF1ab/nsp344V44DgTtgAt11B.1.4290.000024
ORF1ab/nsp344V44QGTTCAG11B.1.4290.000024
ORF1ab/nsp344V44EgTTgAG11B.1.4290.000024
ORF1ab/nsp344V44HGTtCAt11B.1.4290.000024
ORF1ab/nsp344V44VgtTgtC11B.1.4700.001404
ORF1ab/nsp344V44delGTT---11B.1.5610.000397
ORF1ab/nsp344V44VgtTgtC11B.1.617.10.000129
ORF1ab/nsp344V44LGtTTtG11B.1.617.20.000004
ORF1ab/nsp344V44GgTtgGt11B.1.617.20.000004
ORF1ab/nsp344V44AgTtgCt11B.1.6360.006711
ORF1ab/nsp344V44delGTT---11B.570.015152
ORF1ab/nsp344V44IGttAtt11C.170.055556
ORF1ab/nsp344V44AgTtgCt11D.20.000075
ORF1ab/nsp344V44IGttAtt11P.10.000016
ORF1ab/nsp344V44VgtTgtC11P.1.100.000269
ORF1ab/nsp344V44IGttAtt11P.1.140.000048
ORF1ab/nsp344V44VgtTgtC11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.