CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 357

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3357L357FL1175FnonsynttAttT131513090.9954373788-3790
ORF1ab/nsp3357L357FL1175FnonsynttAttC131560.004562743788-3790
ORF1ab/nsp3357L357LL1175LsynTtaCta4193310.7899763788-3790
ORF1ab/nsp3357L357LL1175LsynttAttG419870.2076373788-3790
ORF1ab/nsp3357L357LL1175LsynTtACtC41910.002386633788-3790
ORF1ab/nsp3357L357IL1175InonsynTtaAta626213788-3790
ORF1ab/nsp3357L357VL1175VnonsynTtaGta45430.9555563788-3790
ORF1ab/nsp3357L357VL1175VnonsynTtAGtG4520.04444443788-3790
ORF1ab/nsp3357L357delL1175deldelTTA---414113788-3790
ORF1ab/nsp3357L357SL1175SnonsyntTatCa14100.7142863788-3790
ORF1ab/nsp3357L357SL1175SnonsyntTAtCT1430.2142863788-3790
ORF1ab/nsp3357L357SL1175SnonsyntTAtCG1410.07142863788-3790
ORF1ab/nsp3357L357del1L1175del1delTta-ta13110.8461543788-3790
ORF1ab/nsp3357L357del1L1175del1delTtANt-1310.07692313788-3790
ORF1ab/nsp3357L357del1L1175del1delttAtt-1310.07692313788-3790
ORF1ab/nsp3357L357XL1175XnonsyntTatGa420.53788-3790
ORF1ab/nsp3357L357XL1175XnonsyntTatAa420.53788-3790
ORF1ab/nsp3357L357CL1175CnonsyntTAtGT2213788-3790
ORF1ab/nsp3357L357AL1175AnonsynTTAGCG210.53788-3790
ORF1ab/nsp3357L357AL1175AnonsynTTaGCa210.53788-3790
ORF1ab/nsp3357L357YL1175YnonsyntTAtAT1113788-3790
ORF1ab/nsp3357L357GL1175GnonsynTTaGGa1113788-3790

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3357L357FttAttT13091315All0.00025
ORF1ab/nsp3357L357FttAttC61315All0.000001
ORF1ab/nsp3357L357FttAttT11111111B.1.1.3480.884554
ORF1ab/nsp3357L357LTtaCta331419All0.000063
ORF1ab/nsp3357L357LttAttG87419All0.000017
ORF1ab/nsp3357L357LTtACtC1419All0
ORF1ab/nsp3357L357LTtaCta224224B.1.1.3851
ORF1ab/nsp3357L357FttAttT6970B.1.10.001252
ORF1ab/nsp3357L357FttAttC170B.1.10.000018
ORF1ab/nsp3357L357ITtaAta6262All0.000012
ORF1ab/nsp3357L357ITtaAta5454AY.50.001115
ORF1ab/nsp3357L357VTtaGta4345All0.000008
ORF1ab/nsp3357L357VTtAGtG245All0
ORF1ab/nsp3357L357delTTA---4141All0.000008
ORF1ab/nsp3357L357LTtaCta3340B.10.000302
ORF1ab/nsp3357L357LttAttG740B.10.000064
ORF1ab/nsp3357L357FttAttT3636AY.620.015686
ORF1ab/nsp3357L357FttAttT2829B.10.000256
ORF1ab/nsp3357L357FttAttC129B.10.000009
ORF1ab/nsp3357L357VTtaGta2626B.1.20.000229
ORF1ab/nsp3357L357StTatCa1014All0.000002
ORF1ab/nsp3357L357StTAtCT314All0.000001
ORF1ab/nsp3357L357StTAtCG114All0
ORF1ab/nsp3357L357del1Tta-ta1113All0.000002
ORF1ab/nsp3357L357del1ttAtt-113All0
ORF1ab/nsp3357L357del1TtANt-113All0
ORF1ab/nsp3357L357LTtaCta1213B.1.10.000218
ORF1ab/nsp3357L357LttAttG113B.1.10.000018
ORF1ab/nsp3357L357LttAttG99AY.250.000054
ORF1ab/nsp3357L357LttAttG89AY.30.00008
ORF1ab/nsp3357L357LTtaCta19AY.30.00001
ORF1ab/nsp3357L357LttAttG99AY.430.00004
ORF1ab/nsp3357L357LTtaCta88AY.1200.000297
ORF1ab/nsp3357L357LttAttG88AY.120.10.002568
ORF1ab/nsp3357L357LttAttG88AY.40.000012
ORF1ab/nsp3357L357FttAttT88B.1.1.3070.020253
ORF1ab/nsp3357L357LTtaCta48B.1.1.70.000004
ORF1ab/nsp3357L357LttAttG48B.1.1.70.000004
ORF1ab/nsp3357L357FttAttT88P.1.150.001859
ORF1ab/nsp3357L357delTTA---77B.1.1.70.000006
ORF1ab/nsp3357L357LttAttG77B.1.1110.008226
ORF1ab/nsp3357L357LTtaCta66AY.98.10.000291
ORF1ab/nsp3357L357VTtaGta66B.1.1.70.000005
ORF1ab/nsp3357L357del1Tta-ta66P.10.000095
ORF1ab/nsp3357L357delTTA---55B.10.000046
ORF1ab/nsp3357L357LTtaCta55B.1.1.2200.009294
ORF1ab/nsp3357L357LTtaCta55B.1.1600.000156
ORF1ab/nsp3357L357LTtaCta45B.1.1770.000053
ORF1ab/nsp3357L357LttAttG15B.1.1770.000013
ORF1ab/nsp3357L357delTTA---55B.1.20.000044
ORF1ab/nsp3357L357StTAtCT240.111111
ORF1ab/nsp3357L357StTAtCG140.055556
ORF1ab/nsp3357L357StTatCa140.055556
ORF1ab/nsp3357L357XtTatAa24All0
ORF1ab/nsp3357L357XtTatGa24All0
ORF1ab/nsp3357L357LttAttG24AY.1030.000012
ORF1ab/nsp3357L357LTtaCta24AY.1030.000012
ORF1ab/nsp3357L357LTtaCta24AY.1190.000071
ORF1ab/nsp3357L357LttAttG24AY.1190.000071
ORF1ab/nsp3357L357FttAttT44B.1.1.4170.010811
ORF1ab/nsp3357L357LTtaCta44B.1.20.000035
ORF1ab/nsp3357L357FttAttT44B.1.617.20.000015
ORF1ab/nsp3357L357FttAttT44P.10.000063
ORF1ab/nsp3357L357LttAttG34P.10.000047
ORF1ab/nsp3357L357LTtaCta14P.10.000016
ORF1ab/nsp3357L357FttAttT230.111111
ORF1ab/nsp3357L357LttAttG130.055556
ORF1ab/nsp3357L357LTtaCta130.055556
ORF1ab/nsp3357L357LTtACtC130.055556
ORF1ab/nsp3357L357FttAttC130.055556
ORF1ab/nsp3357L357delTTA---33AY.40.000005
ORF1ab/nsp3357L357VTtaGta33AY.40.000005
ORF1ab/nsp3357L357LTtaCta33AY.440.000018
ORF1ab/nsp3357L357FttAttT33B.1.1.1800.032258
ORF1ab/nsp3357L357FttAttT33B.1.1.2690.00406
ORF1ab/nsp3357L357VTtaGta33B.1.177.110.005093
ORF1ab/nsp3357L357LttAttG33B.1.617.20.000011
ORF1ab/nsp3357L357LttAttG33B.430.042857
ORF1ab/nsp3357L357CtTAtGT220.111111
ORF1ab/nsp3357L357ATTaGCa120.055556
ORF1ab/nsp3357L357VTtAGtG120.055556
ORF1ab/nsp3357L357VTtaGta120.055556
ORF1ab/nsp3357L357ATTAGCG120.055556
ORF1ab/nsp3357L357FttAttT22A.2.5.30.020619
ORF1ab/nsp3357L357CtTAtGT22All0
ORF1ab/nsp3357L357ATTaGCa12All0
ORF1ab/nsp3357L357ATTAGCG12All0
ORF1ab/nsp3357L357FttAttT22AY.160.000759
ORF1ab/nsp3357L357ITtaAta22AY.250.000012
ORF1ab/nsp3357L357LTtaCta22B.1.1.1290.018349
ORF1ab/nsp3357L357FttAttT22B.1.1.1740.006757
ORF1ab/nsp3357L357FttAttT22B.1.1.3720.001377
ORF1ab/nsp3357L357StTAtCT12B.1.1.4090.002833
ORF1ab/nsp3357L357StTatCa12B.1.1.4090.002833
ORF1ab/nsp3357L357StTatCa22B.1.1.70.000002
ORF1ab/nsp3357L357LTtaCta22B.1.160.120.012821
ORF1ab/nsp3357L357LttAttG22B.1.160.280.005848
ORF1ab/nsp3357L357delTTA---22B.1.5960.000174
ORF1ab/nsp3357L357ITtaAta22B.1.617.20.000008
ORF1ab/nsp3357L357delTTA---22B.1.6210.000177
ORF1ab/nsp3357L357LttAttG22B.30.001661
ORF1ab/nsp3357L357delTTA---22P.1.120.000968
ORF1ab/nsp3357L357del1Tta-ta22P.1.140.000096
ORF1ab/nsp3357L357LttAttG11A0.000387
ORF1ab/nsp3357L357GTTaGGa11All0
ORF1ab/nsp3357L357YtTAtAT11All0
ORF1ab/nsp3357L357LttAttG11AY.1130.000142
ORF1ab/nsp3357L357LTtaCta11AY.1140.000231
ORF1ab/nsp3357L357FttAttT11AY.1210.000135
ORF1ab/nsp3357L357LTtaCta11AY.140.000088
ORF1ab/nsp3357L357FttAttC11AY.290.000016
ORF1ab/nsp3357L357VTtaGta11AY.30.00001
ORF1ab/nsp3357L357XtTatAa11AY.40.000002
ORF1ab/nsp3357L357FttAttT11AY.40.000002
ORF1ab/nsp3357L357ITtaAta11AY.40.000002
ORF1ab/nsp3357L357LTtaCta11AY.4.20.000022
ORF1ab/nsp3357L357LTtaCta11AY.4.2.10.000149
ORF1ab/nsp3357L357delTTA---11AY.4.50.000107
ORF1ab/nsp3357L357delTTA---11AY.430.000004
ORF1ab/nsp3357L357del1Tta-ta11AY.440.000006
ORF1ab/nsp3357L357StTatCa11AY.440.000006
ORF1ab/nsp3357L357LttAttG11AY.450.000122
ORF1ab/nsp3357L357LTtaCta11AY.510.000909
ORF1ab/nsp3357L357VTtaGta11AY.530.000288
ORF1ab/nsp3357L357ITtaAta11AY.650.000533
ORF1ab/nsp3357L357StTatCa11AY.800.001129
ORF1ab/nsp3357L357FttAttT11AY.910.00073
ORF1ab/nsp3357L357XtTatGa11B0.000128
ORF1ab/nsp3357L357LttAttG11B0.000128
ORF1ab/nsp3357L357VTtAGtG11B.10.000009
ORF1ab/nsp3357L357del1Tta-ta11B.10.000009
ORF1ab/nsp3357L357ITtaAta11B.10.000009
ORF1ab/nsp3357L357delTTA---11B.1.10.000018
ORF1ab/nsp3357L357StTatCa11B.1.1.10.000327
ORF1ab/nsp3357L357FttAttT11B.1.1.100.001115
ORF1ab/nsp3357L357FttAttT11B.1.1.1710.003676
ORF1ab/nsp3357L357LTtaCta11B.1.1.1980.001468
ORF1ab/nsp3357L357FttAttT11B.1.1.1980.001468
ORF1ab/nsp3357L357FttAttT11B.1.1.2200.001859
ORF1ab/nsp3357L357LTtaCta11B.1.1.250.000569
ORF1ab/nsp3357L357FttAttT11B.1.1.280.000311
ORF1ab/nsp3357L357LTtaCta11B.1.1.3050.003861
ORF1ab/nsp3357L357delTTA---11B.1.1.330.000421
ORF1ab/nsp3357L357LTtaCta11B.1.1.390.00051
ORF1ab/nsp3357L357FttAttT11B.1.1.3980.003226
ORF1ab/nsp3357L357FttAttT11B.1.1.4090.002833
ORF1ab/nsp3357L357XtTatAa11B.1.1.4090.002833
ORF1ab/nsp3357L357YtTAtAT11B.1.1.4090.002833
ORF1ab/nsp3357L357FttAttT11B.1.1.4160.000905
ORF1ab/nsp3357L357FttAttT11B.1.1.4420.018519
ORF1ab/nsp3357L357del1ttAtt-11B.1.1.460.004367
ORF1ab/nsp3357L357FttAttT11B.1.1.4620.008621
ORF1ab/nsp3357L357FttAttT11B.1.1.5140.038462
ORF1ab/nsp3357L357LTtaCta11B.1.1.5190.00004
ORF1ab/nsp3357L357del1Tta-ta11B.1.1.70.000001
ORF1ab/nsp3357L357ITtaAta11B.1.1.70.000001
ORF1ab/nsp3357L357FttAttT11B.1.1.890.006061
ORF1ab/nsp3357L357delTTA---11B.1.1600.000031
ORF1ab/nsp3357L357StTatCa11B.1.1770.000013
ORF1ab/nsp3357L357FttAttC11B.1.177.450.000381
ORF1ab/nsp3357L357FttAttT11B.1.20.000009
ORF1ab/nsp3357L357StTatCa11B.1.20.000009
ORF1ab/nsp3357L357delTTA---11B.1.2180.005155
ORF1ab/nsp3357L357LttAttG11B.1.2210.000071
ORF1ab/nsp3357L357VTtaGta11B.1.2220.001692
ORF1ab/nsp3357L357XtTatGa11B.1.3320.003497
ORF1ab/nsp3357L357delTTA---11B.1.360.000146
ORF1ab/nsp3357L357FttAttT11B.1.3960.000706
ORF1ab/nsp3357L357del1TtANt-11B.1.4290.000024
ORF1ab/nsp3357L357delTTA---11B.1.4290.000024
ORF1ab/nsp3357L357LttAttG11B.1.4360.001029
ORF1ab/nsp3357L357StTatCa11B.1.466.20.000391
ORF1ab/nsp3357L357delTTA---11B.1.5260.000024
ORF1ab/nsp3357L357FttAttT11B.1.5350.028571
ORF1ab/nsp3357L357FttAttC11B.1.5640.000426
ORF1ab/nsp3357L357delTTA---11B.1.5950.000261
ORF1ab/nsp3357L357FttAttT11B.1.6090.000479
ORF1ab/nsp3357L357delTTA---11B.1.617.20.000004
ORF1ab/nsp3357L357LTtaCta11B.1.6210.000089
ORF1ab/nsp3357L357VTtaGta11B.1.6270.00202
ORF1ab/nsp3357L357delTTA---11B.4.40.018868
ORF1ab/nsp3357L357delTTA---11B.570.015152
ORF1ab/nsp3357L357delTTA---11N.60.007092
ORF1ab/nsp3357L357delTTA---11P.10.000016
ORF1ab/nsp3357L357GTTaGGa11P.10.000016
ORF1ab/nsp3357L357FttAttT11P.1.120.000484
ORF1ab/nsp3357L357LttAttG11P.1.140.000048
ORF1ab/nsp3357L357FttAttT11P.1.160.000374
ORF1ab/nsp3357L357LTtaCta11Q.40.000455

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.