CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 217 & Codon = aAt

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp3217T217NT1035NnonsynaCtaAt636313368-3370

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp3217T217NaCtaAt6363All0.000012
ORF1ab/nsp3217T217NaCtaAt2424B.1.1.70.000021
ORF1ab/nsp3217T217NaCtaAt1313B.1.617.20.000049
ORF1ab/nsp3217T217NaCtaAt55AY.40.000008
ORF1ab/nsp3217T217NaCtaAt44B.1.1.2530.010025
ORF1ab/nsp3217T217NaCtaAt33AY.30.00003
ORF1ab/nsp3217T217NaCtaAt33AY.4.40.001227
ORF1ab/nsp3217T217NaCtaAt22B.10.000018
ORF1ab/nsp3217T217NaCtaAt22B.1.20.000018
ORF1ab/nsp3217T217NaCtaAt22B.1.466.20.000782
ORF1ab/nsp3217T217NaCtaAt22B.1.6210.000177
ORF1ab/nsp3217T217NaCtaAt11A0.000387
ORF1ab/nsp3217T217NaCtaAt11AY.1030.000006
ORF1ab/nsp3217T217NaCtaAt11P.10.000016

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

CoV-GLUE uses sequence data from GISAID. GISAID data provided via this web application is subject to GISAID's Terms and Conditions.