CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 1251 & Codon = acA

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31251T1251TT2069TsynacCacA21704180.1926276470-6472

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31251T1251TacCacA4182170All0.00008
ORF1ab/nsp31251T1251TacCacA167698B.1.1.70.00015
ORF1ab/nsp31251T1251TacCacA10116AY.40.000016
ORF1ab/nsp31251T1251TacCacA65109B.1.617.20.000245
ORF1ab/nsp31251T1251TacCacA1102B.1.20.000009
ORF1ab/nsp31251T1251TacCacA265AY.99.20.000184
ORF1ab/nsp31251T1251TacCacA1553AY.440.000091
ORF1ab/nsp31251T1251TacCacA3745AY.1020.000981
ORF1ab/nsp31251T1251TacCacA938AY.250.000054
ORF1ab/nsp31251T1251TacCacA638AY.390.000148
ORF1ab/nsp31251T1251TacCacA526B.10.000046
ORF1ab/nsp31251T1251TacCacA123AY.46.60.000072
ORF1ab/nsp31251T1251TacCacA122AY.1030.000006
ORF1ab/nsp31251T1251TacCacA1520B.1.1770.000198
ORF1ab/nsp31251T1251TacCacA818AY.430.000035
ORF1ab/nsp31251T1251TacCacA516B.1.177.770.003631
ORF1ab/nsp31251T1251TacCacA914B.1.10.000163
ORF1ab/nsp31251T1251TacCacA1313AY.80.007879
ORF1ab/nsp31251T1251TacCacA313B.1.4290.000071
ORF1ab/nsp31251T1251TacCacA68AY.330.000401
ORF1ab/nsp31251T1251TacCacA15AY.230.00007
ORF1ab/nsp31251T1251TacCacA15B.1.5260.000024
ORF1ab/nsp31251T1251TacCacA14AY.420.00004
ORF1ab/nsp31251T1251TacCacA24B.1.1.2940.002532
ORF1ab/nsp31251T1251TacCacA44B.1.1.500.002716
ORF1ab/nsp31251T1251TacCacA13AY.450.000122
ORF1ab/nsp31251T1251TacCacA33AY.540.000286
ORF1ab/nsp31251T1251TacCacA13B.1.177.600.000218
ORF1ab/nsp31251T1251TacCacA13B.1.2210.000071
ORF1ab/nsp31251T1251TacCacA23B.1.3510.000059
ORF1ab/nsp31251T1251TacCacA33B.1.3620.004622
ORF1ab/nsp31251T1251TacCacA22AY.1170.000169
ORF1ab/nsp31251T1251TacCacA12AY.460.000104
ORF1ab/nsp31251T1251TacCacA12AY.550.000917
ORF1ab/nsp31251T1251TacCacA12AY.750.000056
ORF1ab/nsp31251T1251TacCacA110.055556
ORF1ab/nsp31251T1251TacCacA11AY.110.001339
ORF1ab/nsp31251T1251TacCacA11AY.1180.000063
ORF1ab/nsp31251T1251TacCacA11AY.1210.000135
ORF1ab/nsp31251T1251TacCacA11AY.34.10.00051
ORF1ab/nsp31251T1251TacCacA11AY.470.000031
ORF1ab/nsp31251T1251TacCacA11B0.000128
ORF1ab/nsp31251T1251TacCacA11B.1.1.250.000569
ORF1ab/nsp31251T1251TacCacA11B.1.1.390.00051
ORF1ab/nsp31251T1251TacCacA11B.1.1.700.000341
ORF1ab/nsp31251T1251TacCacA11B.1.1640.014925
ORF1ab/nsp31251T1251TacCacA11B.1.177.350.000691
ORF1ab/nsp31251T1251TacCacA11B.1.177.560.000668
ORF1ab/nsp31251T1251TacCacA11C.400.027778
ORF1ab/nsp31251T1251TacCacA11Q.10.000126

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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