CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp3 : CodonNum = 1230 & Codon = tTt

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp31230S1230FS2048FnonsyntCttTt34945349440.9999716407-6409

Details of the mutation no within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp31230S1230FtCttTt3494434945All0.006683
ORF1ab/nsp31230S1230FtCttTt2371923719AY.1200.881846
ORF1ab/nsp31230S1230FtCttTt34243425AY.40.005329
ORF1ab/nsp31230S1230FtCttTt30063006AY.120.10.965008
ORF1ab/nsp31230S1230FtCttTt20012001AY.120.2.10.99701
ORF1ab/nsp31230S1230FtCttTt704704AY.120.20.904884
ORF1ab/nsp31230S1230FtCttTt549549AY.1030.003409
ORF1ab/nsp31230S1230FtCttTt387387B.1.617.20.001457
ORF1ab/nsp31230S1230FtCttTt314314B.1.1.70.000281
ORF1ab/nsp31230S1230FtCttTt152152B.10.001392
ORF1ab/nsp31230S1230FtCttTt8080B.1.1770.001053
ORF1ab/nsp31230S1230FtCttTt6161AY.30.000607
ORF1ab/nsp31230S1230FtCttTt4949AY.320.026092
ORF1ab/nsp31230S1230FtCttTt3838AY.1190.001342
ORF1ab/nsp31230S1230FtCttTt3636AY.4.20.000781
ORF1ab/nsp31230S1230FtCttTt3333AY.430.000146
ORF1ab/nsp31230S1230FtCttTt2929Q.10.003663
ORF1ab/nsp31230S1230FtCttTt2323B.1.4290.000541
ORF1ab/nsp31230S1230FtCttTt1919AY.1020.000504
ORF1ab/nsp31230S1230FtCttTt1616AY.260.000453
ORF1ab/nsp31230S1230FtCttTt1616AY.390.000395
ORF1ab/nsp31230S1230FtCttTt1515AY.440.000091
ORF1ab/nsp31230S1230FtCttTt1414AY.4.50.001505
ORF1ab/nsp31230S1230FtCttTt1414B.1.5260.000329
ORF1ab/nsp31230S1230FtCttTt1212AY.90.000811
ORF1ab/nsp31230S1230FtCttTt1111AY.50.000227
ORF1ab/nsp31230S1230FtCttTt1111AY.60.000452
ORF1ab/nsp31230S1230FtCttTt1111B.1.1.1650.169231
ORF1ab/nsp31230S1230FtCttTt99AY.460.000937
ORF1ab/nsp31230S1230FtCttTt88AY.1000.000368
ORF1ab/nsp31230S1230FtCttTt77AY.250.000042
ORF1ab/nsp31230S1230FtCttTt77B.1.20.000062
ORF1ab/nsp31230S1230FtCttTt66B.1.10.000109
ORF1ab/nsp31230S1230FtCttTt66B.1.2400.001293
ORF1ab/nsp31230S1230FtCttTt66B.1.3510.000178
ORF1ab/nsp31230S1230FtCttTt66P.10.000095
ORF1ab/nsp31230S1230FtCttTt55AY.230.000349
ORF1ab/nsp31230S1230FtCttTt55AY.420.000201
ORF1ab/nsp31230S1230FtCttTt55AY.46.10.005133
ORF1ab/nsp31230S1230FtCttTt55AY.750.00028
ORF1ab/nsp31230S1230FtCttTt55B.1.1.5190.000199
ORF1ab/nsp31230S1230FtCttTt55B.1.2390.006105
ORF1ab/nsp31230S1230FtCttTt44AY.1170.000338
ORF1ab/nsp31230S1230FtCttTt44AY.450.000487
ORF1ab/nsp31230S1230FtCttTt44AY.540.000381
ORF1ab/nsp31230S1230FtCttTt44AY.790.004843
ORF1ab/nsp31230S1230FtCttTt44B.1.243.10.088889
ORF1ab/nsp31230S1230FtCttTt44B.1.6090.001918
ORF1ab/nsp31230S1230FtCttTt33AY.1060.001005
ORF1ab/nsp31230S1230FtCttTt33AY.470.000093
ORF1ab/nsp31230S1230FtCttTt33AY.920.000862
ORF1ab/nsp31230S1230FtCttTt33AY.99.20.000276
ORF1ab/nsp31230S1230FtCttTt33B.1.360.000438
ORF1ab/nsp31230S1230FtCttTt22AY.1100.000225
ORF1ab/nsp31230S1230FtCttTt22AY.200.000078
ORF1ab/nsp31230S1230FtCttTt22AY.3.10.000171
ORF1ab/nsp31230S1230FtCttTt22AY.39.10.000079
ORF1ab/nsp31230S1230FtCttTt22AY.5.30.000675
ORF1ab/nsp31230S1230FtCttTt22AY.680.000547
ORF1ab/nsp31230S1230FtCttTt22AY.840.000875
ORF1ab/nsp31230S1230FtCttTt22B.1.1.2050.007435
ORF1ab/nsp31230S1230FtCttTt22B.1.1.3060.000877
ORF1ab/nsp31230S1230FtCttTt22B.1.1.700.000682
ORF1ab/nsp31230S1230FtCttTt22B.1.1100.00905
ORF1ab/nsp31230S1230FtCttTt22B.1.2580.000133
ORF1ab/nsp31230S1230FtCttTt22B.1.466.20.000782
ORF1ab/nsp31230S1230FtCttTt22B.1.6210.000177
ORF1ab/nsp31230S1230FtCttTt22B.1.80.003945
ORF1ab/nsp31230S1230FtCttTt22Q.80.00033
ORF1ab/nsp31230S1230FtCttTt110.055556
ORF1ab/nsp31230S1230FtCttTt11AY.1210.000135
ORF1ab/nsp31230S1230FtCttTt11AY.140.000088
ORF1ab/nsp31230S1230FtCttTt11AY.290.000016
ORF1ab/nsp31230S1230FtCttTt11AY.370.000316
ORF1ab/nsp31230S1230FtCttTt11AY.380.000499
ORF1ab/nsp31230S1230FtCttTt11AY.5.40.000277
ORF1ab/nsp31230S1230FtCttTt11AY.520.000814
ORF1ab/nsp31230S1230FtCttTt11AY.550.000917
ORF1ab/nsp31230S1230FtCttTt11AY.560.001605
ORF1ab/nsp31230S1230FtCttTt11AY.580.000907
ORF1ab/nsp31230S1230FtCttTt11AY.620.000436
ORF1ab/nsp31230S1230FtCttTt11AY.7.10.000113
ORF1ab/nsp31230S1230FtCttTt11AY.930.000273
ORF1ab/nsp31230S1230FtCttTt11AY.980.000079
ORF1ab/nsp31230S1230FtCttTt11AY.98.10.000048
ORF1ab/nsp31230S1230FtCttTt11B0.000128
ORF1ab/nsp31230S1230FtCttTt11B.1.1.280.000311
ORF1ab/nsp31230S1230FtCttTt11B.1.1.330.000421
ORF1ab/nsp31230S1230FtCttTt11B.1.1.340.013158
ORF1ab/nsp31230S1230FtCttTt11B.1.1.3480.000796
ORF1ab/nsp31230S1230FtCttTt11B.1.1.4160.000905
ORF1ab/nsp31230S1230FtCttTt11B.1.1.460.004367
ORF1ab/nsp31230S1230FtCttTt11B.1.1600.000031
ORF1ab/nsp31230S1230FtCttTt11B.1.1640.014925
ORF1ab/nsp31230S1230FtCttTt11B.1.177.860.000183
ORF1ab/nsp31230S1230FtCttTt11B.1.2140.003663
ORF1ab/nsp31230S1230FtCttTt11B.1.258.170.000104
ORF1ab/nsp31230S1230FtCttTt11B.1.351.30.000876
ORF1ab/nsp31230S1230FtCttTt11B.1.3610.001289
ORF1ab/nsp31230S1230FtCttTt11B.1.3750.00082
ORF1ab/nsp31230S1230FtCttTt11B.1.4590.004082
ORF1ab/nsp31230S1230FtCttTt11B.1.5250.000113
ORF1ab/nsp31230S1230FtCttTt11B.1.5740.002151
ORF1ab/nsp31230S1230FtCttTt11B.1.5950.000261
ORF1ab/nsp31230S1230FtCttTt11B.1.5990.00365
ORF1ab/nsp31230S1230FtCttTt11B.1.617.10.000129
ORF1ab/nsp31230S1230FtCttTt11B.610.005747
ORF1ab/nsp31230S1230FtCttTt11C.370.000116
ORF1ab/nsp31230S1230FtCttTt11D.20.000075
ORF1ab/nsp31230S1230FtCttTt11P.1.10.000318
ORF1ab/nsp31230S1230FtCttTt11P.1.60.001946
ORF1ab/nsp31230S1230FtCttTt11R.10.00009
ORF1ab/nsp31230S1230FtCttTt11W.10.008696

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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