CoV-GLUEGenomeCountriesLineagesMutationsInsertionsDeletionsUpdated:

CoV-GLUE | Mutations | Mutation

CoV-GLUE Mutation: ORF = ORF1ab/nsp2 : Mut = V571L

Details of the codons used for the mutation across all lineages (CodonProp is the proportion each codon is used for this AA mutation):

ORFCodonNumMutORF1abMutMutTypeRefCodonMutCodonAACountCodonCountCodonPropGenome Position
ORF1ab/nsp2571V571LV751LnonsynGtgTtg500850020.9988022516-2518
ORF1ab/nsp2571V571LV751LnonsynGtgCtg500840.0007987222516-2518
ORF1ab/nsp2571V571LV751LnonsynGtGCtT500820.0003993612516-2518

Details of the mutation V571L within lineages (LineageCodonProp is the proportion the codon is observed at, at this particular site, on each lineage):

ORFCodonNumMutRefCodonMutCodonCodonCountAACountLineageLineageCodonProp
ORF1ab/nsp2571V571LGtgTtg50025008All0.000957
ORF1ab/nsp2571V571LGtgCtg45008All0.000001
ORF1ab/nsp2571V571LGtGCtT25008All0
ORF1ab/nsp2571V571LGtgTtg24392439B.1.5610.968241
ORF1ab/nsp2571V571LGtgTtg18561857AY.40.002889
ORF1ab/nsp2571V571LGtgCtg11857AY.40.000002
ORF1ab/nsp2571V571LGtgTtg148148B.1.617.20.000557
ORF1ab/nsp2571V571LGtgTtg145145B.1.1.70.00013
ORF1ab/nsp2571V571LGtgTtg9494B.10.000861
ORF1ab/nsp2571V571LGtgTtg4747B.1.177.860.008622
ORF1ab/nsp2571V571LGtgTtg3030AY.750.001681
ORF1ab/nsp2571V571LGtgTtg2222AY.1020.000583
ORF1ab/nsp2571V571LGtgTtg1616B.1.20.000141
ORF1ab/nsp2571V571LGtgTtg1313B.1.1.2220.002652
ORF1ab/nsp2571V571LGtgTtg1010AY.1200.000372
ORF1ab/nsp2571V571LGtgTtg99B.1.360.001313
ORF1ab/nsp2571V571LGtgTtg88AY.1030.00005
ORF1ab/nsp2571V571LGtgTtg88AY.430.000035
ORF1ab/nsp2571V571LGtgTtg78B.1.10.000127
ORF1ab/nsp2571V571LGtgCtg18B.1.10.000018
ORF1ab/nsp2571V571LGtgTtg88B.1.1600.00025
ORF1ab/nsp2571V571LGtgTtg77AY.420.000282
ORF1ab/nsp2571V571LGtgTtg66AY.1190.000212
ORF1ab/nsp2571V571LGtgTtg66AY.410.001764
ORF1ab/nsp2571V571LGtgTtg66B.1.1.4160.00543
ORF1ab/nsp2571V571LGtgTtg66B.1.5750.00182
ORF1ab/nsp2571V571LGtgTtg66P.10.000095
ORF1ab/nsp2571V571LGtgTtg55B.1.1770.000066
ORF1ab/nsp2571V571LGtgTtg55B.1.2810.108696
ORF1ab/nsp2571V571LGtgTtg55B.1.5820.002453
ORF1ab/nsp2571V571LGtgTtg55B.1.6180.020161
ORF1ab/nsp2571V571LGtgTtg44AY.390.000099
ORF1ab/nsp2571V571LGtgTtg44AY.460.000416
ORF1ab/nsp2571V571LGtgTtg44B.1.1.270.022599
ORF1ab/nsp2571V571LGtgTtg44B.1.36.100.019139
ORF1ab/nsp2571V571LGtgTtg23AY.250.000012
ORF1ab/nsp2571V571LGtgCtg13AY.250.000006
ORF1ab/nsp2571V571LGtgTtg33AY.330.0002
ORF1ab/nsp2571V571LGtgTtg33AY.910.002191
ORF1ab/nsp2571V571LGtgTtg33B.1.4970.000944
ORF1ab/nsp2571V571LGtGCtT220.111111
ORF1ab/nsp2571V571LGtgTtg22AY.140.000176
ORF1ab/nsp2571V571LGtgTtg22AY.4.20.000043
ORF1ab/nsp2571V571LGtgTtg22AY.440.000012
ORF1ab/nsp2571V571LGtgTtg22AY.540.000191
ORF1ab/nsp2571V571LGtgTtg22AY.60.000082
ORF1ab/nsp2571V571LGtgTtg22AY.650.001066
ORF1ab/nsp2571V571LGtgTtg22AY.740.000231
ORF1ab/nsp2571V571LGtgTtg22B.1.1390.001466
ORF1ab/nsp2571V571LGtgTtg22B.1.2320.001075
ORF1ab/nsp2571V571LGtgTtg22B.1.3110.000549
ORF1ab/nsp2571V571LGtgTtg22B.1.3510.000059
ORF1ab/nsp2571V571LGtgTtg22B.1.36.380.003284
ORF1ab/nsp2571V571LGtgTtg22B.1.4290.000047
ORF1ab/nsp2571V571LGtgTtg22B.1.438.10.000215
ORF1ab/nsp2571V571LGtgTtg22B.1.5550.044444
ORF1ab/nsp2571V571LGtgTtg22B.1.5710.019417
ORF1ab/nsp2571V571LGtgTtg11A.60.005128
ORF1ab/nsp2571V571LGtgTtg11AY.16.10.00047
ORF1ab/nsp2571V571LGtgTtg11AY.230.00007
ORF1ab/nsp2571V571LGtgTtg11AY.260.000028
ORF1ab/nsp2571V571LGtgTtg11AY.34.10.00051
ORF1ab/nsp2571V571LGtgTtg11AY.4.50.000107
ORF1ab/nsp2571V571LGtgTtg11AY.46.50.000198
ORF1ab/nsp2571V571LGtgTtg11AY.50.000021
ORF1ab/nsp2571V571LGtgTtg11AY.5.40.000277
ORF1ab/nsp2571V571LGtgTtg11AY.800.001129
ORF1ab/nsp2571V571LGtgTtg11B.1.1.2140.000055
ORF1ab/nsp2571V571LGtgTtg11B.1.1.3060.000438
ORF1ab/nsp2571V571LGtgCtg11B.1.1.4590.015385
ORF1ab/nsp2571V571LGtgTtg11B.1.177.200.001517
ORF1ab/nsp2571V571LGtgTtg11B.1.2430.00007
ORF1ab/nsp2571V571LGtgTtg11B.1.2470.014925
ORF1ab/nsp2571V571LGtgTtg11B.1.36.180.00042
ORF1ab/nsp2571V571LGtgTtg11B.1.36.390.002217
ORF1ab/nsp2571V571LGtgTtg11B.1.3690.000285
ORF1ab/nsp2571V571LGtgTtg11B.1.3960.000706
ORF1ab/nsp2571V571LGtgTtg11B.1.429.10.012048
ORF1ab/nsp2571V571LGtgTtg11B.1.4600.017857
ORF1ab/nsp2571V571LGtgTtg11B.1.466.20.000391
ORF1ab/nsp2571V571LGtgTtg11B.1.5260.000024
ORF1ab/nsp2571V571LGtgTtg11B.1.6100.003546
ORF1ab/nsp2571V571LGtgTtg11P.1.70.000319
ORF1ab/nsp2571V571LGtgTtg11Q.30.000145

CoV-GLUE is still in development. CoV-GLUE was originally developed as part of COG-UK by Josh Singer using the GLUE framework at the MRC-University of Glasgow Centre for Virus Research (CVR). In 2021 it was redeveloped by Richard Orton to scale to the millions of genome sequences available. We acknowledge support from the MRC (MC_UU_12014/12), WT (220977/Z/20/Z) and UKRI G2P (MR/W005611/1). Please contact Richard Orton with any queries: Richard.Orton@glasgow.ac.uk

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